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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Weight gain on mounjaro

232 replies

Polkadotdash · 17/01/2025 10:32

Any else experience this? I’m just starting my 4th week on 2.5mg. I lost a few pounds in my first week on it, but these are back on now. I’ve had no effects at all from the injections - good or bad. I’ve already bought the 5mg dose to start next week, but I’m starting to wonder if it’s worth the cost. I bought from a big online pharmacy so I’m assuming that I haven’t been sent a placebo or anything. But it’s really doing nothing for me, apart from costing me money! Am I alone in this?

OP posts:
Polkadotdash · 17/01/2025 23:31

mollymazda · 17/01/2025 23:19

😂😂. I am right! and poster after poster after poster has said exactly the same as me.

If you look back through the thread, you will see that people have challenged you.

But you’ve totally derailed it by making it all about you shouting ‘You’re fat because you eat too much’ at me. Thanks for that. So inspiring.

OP posts:
FlipYouCouldBeMe · 17/01/2025 23:32

Hang in there OP. Lots of people don't loose on 2.5mg. You might need 5 or even 7.5mg or more til you start to feel the effects. Good luck

Polkadotdash · 17/01/2025 23:33

FlipYouCouldBeMe · 17/01/2025 23:32

Hang in there OP. Lots of people don't loose on 2.5mg. You might need 5 or even 7.5mg or more til you start to feel the effects. Good luck

Thank you. I’m really hoping that I get some benefits from the next dose up.

OP posts:
mollymazda · 17/01/2025 23:34

This reply has been deleted

Message deleted by MNHQ. Here's a link to our Talk Guidelines.

oh for the love of god... you know what, i give up! swear at me, be angry at me, take it all out on me...

i do not doubt that enough people will come after i have gone and say exactly the same as i have.

YOU NEED TO COUNT CALORIES!!!

ThatEllie · 18/01/2025 00:23

Oh good grief, this is why I hate these online calculators. They’ll claim that a woman who is, for example, 5’2”, 48 years old, 12 stone and sedentary has a TDEE of 1900. So she eats that and then gains weight because her actual TDEE is closer to 1350. People don’t realize that these websites just care about the ad revenue from traffic and are not trustworthy sources of information.

Forget the 2200. Your TDEE is not that high unless you’ve forgotten to mention that you swim 4 km a day. Other than that, as others mentioned you will have to change your diet to reduce the carbs and both reduce and track calories. The ill feeling is partially due to your lunch and partially due to your brain/conditioning. Since you’re reluctant to change anything, perhaps start with reducing the lunch but adding another protein bar to help you feel full without as much of a spike/crash.

Weepixie · 18/01/2025 04:11

@ThatEllie hate the online calculators as much as you want. It will never change the fact they work for many millions of people the whole world over.

And as for people not realising blah blah blah blah - stop being ridiculous.

Weepixie · 18/01/2025 04:26

@RobinEllacotStrike

All weight loss on MJ are from calorie deficit & exercise. MJ doesn't itself make you lose weight- it creates conditions which encourage & support you to eat a lot less

Thats it in a nutshell Robin and hopefully the OP will concentrate on what you’ve said and be able to move forward on her journey.

InkHeart2024 · 18/01/2025 04:52

gimmemounjaro · 17/01/2025 21:00

Yes, this happened to me 🙋‍♀️

On 2.5mg, week 1, lost about 5lbs, week 2 lost 1lb, week 3 gained 1lb, week 4 gained 1lb. Ugh.

So I lost 4lbs in 4 weeks.

Then I went up to 5mg and lost more than that in the first 4 days. I lost 13lbs in 4 weeks on 5mg and have carried on losing steadily since, now nearly 4 stone down in 6.5 months. And that's including that first rubbish month on 2.5mg.

Keep going, give it a chance and see what happens when you get to a therapeutic dose.

But you didn't gain weight? You lost 4lbs in a month. The initial 6lbs wasn't all fat loss so over the next 2 weeks your body balanced out and at the end of the month you were 4lbs down. How could you have gained weight eating in a calorie deficit?

InkHeart2024 · 18/01/2025 04:56

ThatEllie · 18/01/2025 00:23

Oh good grief, this is why I hate these online calculators. They’ll claim that a woman who is, for example, 5’2”, 48 years old, 12 stone and sedentary has a TDEE of 1900. So she eats that and then gains weight because her actual TDEE is closer to 1350. People don’t realize that these websites just care about the ad revenue from traffic and are not trustworthy sources of information.

Forget the 2200. Your TDEE is not that high unless you’ve forgotten to mention that you swim 4 km a day. Other than that, as others mentioned you will have to change your diet to reduce the carbs and both reduce and track calories. The ill feeling is partially due to your lunch and partially due to your brain/conditioning. Since you’re reluctant to change anything, perhaps start with reducing the lunch but adding another protein bar to help you feel full without as much of a spike/crash.

Your 12 stone lady absolutely doesn't have a TDEE of 1350. I don't understand why people post this kind of thing. Those calculators are fairly accurate. Someone was claiming similar on another thread and I did the maths and to have a TDEE of 1400 at 12 stone a woman would have to be 4'6 and 78 years old.

TwirlyPineapple · 18/01/2025 05:02

The point of Mounjaro is that it allows people to eat at a deficit who couldn't do that before. Most people overeat either because they are "addicted" to food (aka food noise, cravings), they are genuinely hungrier than normal people or (this one is more contentious) their bodies don't process food in the same way. Mounjaro targets all those things by regulating the relevant hormones.

You say you eat 2,000 calories a day- why? If you're overweight then that is clearly overeating for your lifestyle/body. That is a lot of calories for a woman living an average lifestyle and if you're not eating junk then you must be eating large volumes of food. So examine why you do it. You say you don't have food noise, so is it hunger? That can be regulated with Mounjaro if you're patient.

If you actually can "eat less and move more" then you're right that Mounjaro won't do anything for you that you can't do yourself. The point is that the majority of overeaters can't eat less for the reasons I mentioned above.

InkHeart2024 · 18/01/2025 05:03

mollymazda · 17/01/2025 21:33

it does not make you feel fuller...

...what it does is suppress your appetite! so it makes you not want to eat as much!

but you have to learn to listen to the signals... you can still 'eat through' them! It makes you not want to eat! and i know its sounds the same but i assure you its not..

Um yes it does - it's literally one of the effects of Mounjaro that supports weight loss.

FallenRaingel · 18/01/2025 05:55

@Polkadotdash Try a couple of small changes for a week.

Swap out the protein bar of about 200kcals - assuming this is a Nakd or Nature Valley one with such high calories which means it's also high sugar for such a small amount (40g -55g bar) - with a Ufit high protein 500ml chocolate/salted caramel milkshake. Higher calories (300ish) but 50g protein and will fill you up more than a small bar. It's still portable.

Reduce the calories and still get 26g of protein by mixing half the shake with 250ml of unsweetened almond milk, or skimmed milk increases protein plus sugar.

If you aren't already, swap the cheese for a high protein, reduced fat variety. 50g regular cathedral city is 208kcals, 50g cathedral city high protein half fat is 136cals.

Weigh everything. Especially pasta, bread and cheese. Large portion 240g cooked pasta is 338kcals (362 wholewheat)
36g/40g slice wholemeal bread (without butter) is 79 to 93kcals.

Even if you don't count calories, weighing will help you be very aware of your portion sizes which should make it easier to reduce them.

Small changes make it easier and you won't feel like you're cutting anything but calories.

Shrinkingrose · 18/01/2025 06:27

Hey op.

do you understand that either your tdee is lower than you think or your calorie intake is higher than you think?

you understand you are gaining weight, this is clear. But you repeatedly post you know the cals and your tdee and how you’re 200 under. You seem unable to recognise you are not 200 under, as you’re gaining weight, so it is impossible. You must be over.

as said early for a pound a week, you’re 500 cals a day over, for 2 lbs. You will be a 1000 cals a day over.

so you need to try to work out, is your tdee wrong, or is your cals. Personally I’d say both, and you don’t eat and drink the exact same thing,24/7. It may differ in portion size, or you have treats you neck. Picking at stuff for example.

you may also be quite sendentary, and have a much lower tdee than you think.

the point remains you are very resistance to eating less, and you are not under eating, on this last point, it is not subjective but factual. You are gaining weight, so you’re not under eating. And you need to understand why you think you are, when you’re gaining weight and ate not.

kimchisauchio · 18/01/2025 06:49

Polkadotdash · 17/01/2025 23:31

If you look back through the thread, you will see that people have challenged you.

But you’ve totally derailed it by making it all about you shouting ‘You’re fat because you eat too much’ at me. Thanks for that. So inspiring.

But is “you’re fat because you eat too much” exactly not why you’ve selected mounjaru to help you achieve weight loss?

is rhere any other reason you can point to? Genuine question

kmreeve · 18/01/2025 07:02

Polkadotdash · 17/01/2025 17:02

Typical eating for the day goes like this:
breakfast - Greek yogurt, fruit, protein bar (weekends is toast)
lunch - pasta and vegetables and cheese on top/brown rice veg
snack - biscuit
dinner - cheese salad sandwich or hummus and salad wrap.
two cups of tea a day, one decaf coffee.
Diet Coke with lunch. Water in evening.

I’m really boring and I eat the same things all the time.

Thats 2000 cals. What can I cut from that? I say it’s carb heavy as I eat bread and pasta, no meat or fish.
What I had hoped MJ would do is make me eat smaller portions of things. If I have a smaller lunch, I’m more likely to snack in the afternoon or need to eat something on the way home from work as I feel faint. I thought MJ might help me crack that.
I eat my main meal at lunchtime as my commute is nearly two hours and it’s usually 8pm by the time I get home.

Your diet is poor. It’s carb and sugar heavy. While you say you don’t want to cut the daily calorie intake below 2000, you need to eat better within that. If I ate your daily food I would gain weight guaranteed. It’s not balanced, to processed and full of sugar.

I suspect you feel faint from sugar crashes. You need to work on properly fuelling your body, learning how food and the types of it effect the human body and then you’ll understand how MJ will “assist” you to “learn” these new habits and loose your weight.

LivingLaVidaBabyShower · 18/01/2025 07:12

Yes its happening to me.

I lost 2-3kg pm consistently from week 1 on wegovy. No real side effects.
Then I had to switch to MJ for boring reasons.

12 weeks a million sulphurous burps and the worst farts ever and i am the SAME fucking weight.

Going up to 7.5 next week pray for me.

On your own diet for easy swaps.
I would switch out protein bar for protein powder either mixed in the yoghurt or on the side - you can also get clear protein (its like a squash drink)
Id also leave the cheese out of the pasta and maybe swap out pasta some days and eat some lentils or get lentil / pea pasta which is more protein rich

Mollysay · 18/01/2025 08:14

To be honest from what you've said ie no food noise etc id use the money for a decent online coach (and actual dietician not a self certified nutritionist) and work on hitting macros and what keeps your satiated etc. MJ is great for some, and it'll probably 'kick in' for you on a high dose ie slow your digestion, sort out fullness hormones etc but dunno doesn't seem like it's most suitable.

Polkadotdash · 18/01/2025 09:08

kimchisauchio · 18/01/2025 06:49

But is “you’re fat because you eat too much” exactly not why you’ve selected mounjaru to help you achieve weight loss?

is rhere any other reason you can point to? Genuine question

If you’re asking why I’m fat and is it due to a medical condition, no.
I’m fat, because like most people who have a full time job and kids, I haven’t always had time to do all the things you need to do to not be fat. I haven’t always eaten small amounts, haven’t always not drunk much, haven’t always been exercising. I don’t cope well with stress and I’ve been on anti depressants for years to cope. And the fat has built up over time. Sometimes I’ve lost weight, but always put it back on. I’m currently the heaviest I’ve ever been and I’m sick of it. I have sleep apnoea and I'm anaemic too, so I’m very low on energy. Carrying around all this extra weight is not helping either of those so I need to lose weight to start fixing other stuff.

OP posts:
murraymcgill · 18/01/2025 09:14

@Polkadotdash hi im on 7.5 and I've lost 2st I keep putting on a few lbs lately which is frustrating as I'm eating the same so not sure how it's happening I'm paying 190 a month I can't afford that if it's not working

Weepixie · 18/01/2025 09:16

@Polkadotdash

thats a very honest post and I’m wondering if you could just throw caution to the wind and trust the people here to help you even for a couple of weeks. It can be so easy to get into a downward spiral when we’re feeling so upset with ourselves but we can help you if you’d just let go of the thoughts about your calorie intake and listen to us.

12purplepencils · 18/01/2025 09:21

Good luck OP. 2.5mg didn’t do much for me either but as the higher dose kicked in I have found exactly as you’re hoping. I can happily eat fewer calories in the day without feeling faint or ill or hungry. If I do then a small snack fills me up quickly. (Not that I actually count calories, have always tried to go off hunger signals but was expert at eating when I wasn’t hungry or having portions that were too big)

you might find you need to move to eating more frequently but smaller amounts.

i end up doing almost a version of intermittent fasting where on some days I don’t feel like eating, especially early on in the day.

I’m hopeful on your behalf!

Polkadotdash · 18/01/2025 09:29

Weepixie · 18/01/2025 09:16

@Polkadotdash

thats a very honest post and I’m wondering if you could just throw caution to the wind and trust the people here to help you even for a couple of weeks. It can be so easy to get into a downward spiral when we’re feeling so upset with ourselves but we can help you if you’d just let go of the thoughts about your calorie intake and listen to us.

Thanks. I started this thread just to see if others had experienced what I had with the entry dose of MJ. Everyone in real life who I know who has started on it has had immediate effects - good and bad - and has lost weight. They’ve talked about feeling so full up all the time and not being able to manage to eat anything other than a protein shake and a lettuce leaf. I’ve had no effect from it and I wanted to know if that was also others experience.
What it’s ended up with is a forensic examination of what I eat, how good my grasp of human biology and pharmaceuticals is and a load of assumptions about what I’m doing wrong. There has been some good stuff too about 2.5mg being a starter dose and to not expect anything yet.
Basically - I will be on the 5mg from next week. Maybe it will change my appetite, maybe it won’t. For some it does, for others it won’t. And that’s it really.

OP posts:
SnarkSideOfLife · 18/01/2025 09:30

So on 15mg this is what I ate yesterday

chicken salad sandwich (small bread roll)
chicken breast and half a sweet potato
a pear
a yogurt

didnt eat all the chicken breast as I was full. No desire to snack and wasn’t hungry. No idea what the calories were. I’m not saying it was the best example of healthy eating but it gives an idea of calories I guess.

before mounjaro I’d have been starving if that had been all I’d eaten.

Polkadotdash · 18/01/2025 09:31

@12purplepencils cheers for that. It’s really useful to know that I’m not alone in the no immediate effect group.

OP posts:
12purplepencils · 18/01/2025 09:34

Oh definitely! And still now I’ve never had that “had to force myself to eat” thing people speak of! But there have been some days I’ve forgotten to eat a meal (which for old me would have been unthinkable).

I can eat on it and I have still overeaten on occasion but then I do have binge eating tendencies. It has massively curbed them and I haven’t lost weight as fast as some but (about 2 stone in 6 months which for me is BMI from 35 to 30) but I’m happy with that and was a bit scared of shedding weight very rapidly.