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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Death linked to Mounjaro

412 replies

suki1964 · 08/11/2024 01:18

https://www.bbc.co.uk/news/articles/cz6jg6nw2zeo

I am in no way knocking anyone who is using these drugs, seriously if I could use them I would. However Im throwing this up here because these drugs have only been tested and deemed safe on a small study - those who's BMI is above 30.

Susan McGowan looks into the camera smiling - she has blonde hair in a short bob, black-rimmed glasses and a light grey t-shirt

Nurse's death linked to weight-loss drug Mounjaro approved on NHS

Susan McGowan from North Lanarkshire died two weeks after taking the drug tirzepatide, brand name Mounjaro.

https://www.bbc.co.uk/news/articles/cz6jg6nw2zeo

OP posts:
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10
Wantitalltogoaway · 08/11/2024 13:23

SilenceInside · 08/11/2024 13:10

@Wantitalltogoaway I'm asking why it is that people like me fail to "stack them up" and fail to build these habits into our lives successfully? Every single time over the course of decades. Why does it break down for me, but not for you as a person at a healthy weight? Is it just a personal failing? Lack of sufficient mental strength?

I think only you can answer that?

SilenceInside · 08/11/2024 13:25

@Wantitalltogoaway so, where's the clearly viable alternative, if you have no actual advice for people in my situation?

Searchingforthelight · 08/11/2024 13:53

SilenceInside · 08/11/2024 13:25

@Wantitalltogoaway so, where's the clearly viable alternative, if you have no actual advice for people in my situation?

I believe that poster just wants to tell you off for not having their willpower

Like every other naysayers on these matters!

They are so ignorant- I am embarrassed for them

MrsSkylerWhite · 08/11/2024 13:56

gamerchick · Today 12:41

I take HRT so am used to people criticising my health choices, but I don't get triggered when people point out it's linked to breast cancer

Isn't there new research on that link? The original research is 30 yr old, apparently here are developments and the risk isn't as great as once thought.

Also, there are many different breast cancers. The link with increased risk was only associated with some variants.

Smallsalt · 08/11/2024 14:00

TorroFerney · 08/11/2024 12:57

I think you can get medication can't you if you are a problem drinker that makes you not want the booze so suppose that's similar. That must have side effects. And methadone for drug use and that stuff you paint on your nails to stop you biting them - one could argue they are all "cheating" as you could do those things without the drugs/painty stuff.

It's ok for alcoholics and drug users to get help apparently.
It's just fat people who are "cheats".
It's a truly pathetic outlook from people who are terrified of losing their "slim" kudos and clinging to their notion of somehow being better than over weight people .

SunQueen24 · 08/11/2024 14:02

Wantitalltogoaway · 08/11/2024 13:10

Of course some people are more predisposed than others, but we DO all know that you will not become obese if you don’t build and continue a habit of overeating.

What about environmental factors and your upbringing? Are overweight children, who become obese adults, just as accountable as an adult?

Smallsalt · 08/11/2024 14:03

gamerchick · 08/11/2024 12:17

Can you lie online to get this anti inflammatory drug which is then delivered to your house?

Yes.
It's possible to get the anti inflammatory drug through exactly the same process as getting mounjaro so you could lie .

SunQueen24 · 08/11/2024 14:05

doodleschnoodle · 08/11/2024 13:15

Andrew Jenkinson's work on leptin and ghrelin is really interesting about the role of hormones in metabology.

We talk about a willpower a lot when it comes to weight loss but he makes the point that a) hunger is one of the most primal urges we have. In extreme low cal experiments, participants literally had to be removed for threatening violence to themselves and others and that b) willpower is all very well, but not everyone is starting from the same baseline, and obese people often have shown remarkable willpower from a lifetime of dieting and restricting food in a way that some others haven't had to face. It's clear that 'just eat less and move more' is easy for some people and far more difficult for others, and it's not to do with willpower and may well be due to the way people's bodies work.

His books are very interesting. He himself is a bariatric surgery consultant so has seen a lot of obese people coming through his door and has actually listened to what they are saying.

His work and experience totally undermines people like @Wantitalltogoaway opinions, which they assert as fact, but some people are so ignorant they would rather believe they possess some sort of superiority than accept their opinions are unfounded.

CustardCreams2 · 08/11/2024 14:12

I always advise diet and exercise over quick fixes that don’t exist. Everyone is quick to jump at me quoting safety trials which are very new and not robust. There are risks to this method of weight loss.

JurassicPark4Eva · 08/11/2024 14:20

Wantitalltogoaway · 08/11/2024 12:52

But being morbidly obese isn’t like cancer or Parkinson’s which require certain drugs to control or cure them, some of which have risks or side effects.

Obesity isn’t a disease. It’s a lifestyle choice. There’s another way of treating it that - shock horror - doesn’t include drugs at all.

Wow, you've no clue at all have you?

Wednesdaysdrag · 08/11/2024 14:20

CustardCreams2 · 08/11/2024 14:12

I always advise diet and exercise over quick fixes that don’t exist. Everyone is quick to jump at me quoting safety trials which are very new and not robust. There are risks to this method of weight loss.

Which quick fix?

Who isn’t looking at diet and exercise?

Given you seem to advise a lot of people what profession are you?

CustardCreams2 · 08/11/2024 14:21

It’s true that obesity is a lifestyle choice, not a disease. There are actually vanishingly few medical conditions that cause obesity, especially when said conditions are treated. But again, they are actually incredibly rare. People need to eat less calories that is all.

BleachedJumper · 08/11/2024 14:24

CustardCreams2 · 08/11/2024 14:21

It’s true that obesity is a lifestyle choice, not a disease. There are actually vanishingly few medical conditions that cause obesity, especially when said conditions are treated. But again, they are actually incredibly rare. People need to eat less calories that is all.

And they are, with the aid of WLI, which also has some control of blood sugar levels.

JurassicPark4Eva · 08/11/2024 14:26

CustardCreams2 · 08/11/2024 14:21

It’s true that obesity is a lifestyle choice, not a disease. There are actually vanishingly few medical conditions that cause obesity, especially when said conditions are treated. But again, they are actually incredibly rare. People need to eat less calories that is all.

Have you considered addiction issues? Disordered eating? Which is a mental health issue.

Because that's what most of us who are very obese are actually dealing with. With no help to manage the mental gymnastics of having to eat as a human to live because you can't go cold on food for the rest of your life.

It's not a lifestyle choice.

Pinkbendyman · 08/11/2024 14:29

MrsTerryPratchett · 08/11/2024 04:19

It's a personal decision.

Sort of.

I'm of the opinion that healthcare shouldn't be a business. No advertising, no insta-people, no discount codes. I think risk should be discussed with an actual HCP whose job is your health, and public health, not profit.

It makes me very uncomfortable to see the discounts and online pharmacies. I've had very important discussions with HCPs about whether or not to take various medications, for various medical issues, all of which are a balance with me and the HCP talking about risk, side effects, benefits, LT and SH gain and loss.

What's happening right now is not that.

You raise a very good point regarding the ways in which WLI have been advertised, especially on social media.
I’ve been using Mounjaro since May and it has been life changing for me.
It’s disconcerting though, to hear how people have changed their weight, height, BMI and health conditions in order to buy WLI. Some of these people may already have an existing ED, for example.

CustardCreams2 · 08/11/2024 14:30

Wednesdaysdrag · 08/11/2024 14:20

Which quick fix?

Who isn’t looking at diet and exercise?

Given you seem to advise a lot of people what profession are you?

Medicine.

JurassicPark4Eva · 08/11/2024 14:31

CustardCreams2 · 08/11/2024 14:30

Medicine.

Cleaning in a care home doesn't make you a medically qualified expert in anything.

Anonymousess · 08/11/2024 14:37

It’s important to know if people are dying from this medication and how/why. Especially in a person who doesn’t seem to have pre-existing conditions aside from obesity; which will be the majority of people taking it on this forum. She was only was on the medication for 2 weeks and on the lowest dose. It absolutely was right for OP to post this article here and I’m surprised at the debate otherwise.

Susan is noted as having pancreatitis as a contributing cause of death, which is a high-profile side effect of Mounjaro. It’s possible the organ failure and sepsis were complications of a severe case of pancreatitis. This woman was a medical professional, she presumably had additional insight from her career and education to make an informed decision to take the medication, administer it safety, and when to seek medical help. She still died. It’s concerning. It’s not “one of those things”, it seems like an otherwise avoidable death.

It makes me cringe that much more now reading threads with people that aren’t taking the medication exactly as prescribed.

Wednesdaysdrag · 08/11/2024 14:38

CustardCreams2 · 08/11/2024 14:30

Medicine.

That answers nothing. Working in medicine means nothing.

I wonder why?

Honestly, you can’t be talking about MJ. Because you would know, working in medicine, that it’s not a quick fix. And that diet and exercise are a large part of success on MJ.

If you are talking about MJ, maybe you should educate yourself since it’s relevant to your job in medicine.

SunQueen24 · 08/11/2024 14:40

CustardCreams2 · 08/11/2024 14:21

It’s true that obesity is a lifestyle choice, not a disease. There are actually vanishingly few medical conditions that cause obesity, especially when said conditions are treated. But again, they are actually incredibly rare. People need to eat less calories that is all.

Would you say the same to an anorexic? And if not, why?

Mrsredlipstick · 08/11/2024 14:40

These issues do need to be reported but prior to this very sad situation no deaths had been attributed to Mounjaro. Semiglutinade had 23. Semiglutinade has a twenty year history.
What is not known here is the actual length of pancreatic disease. Invasive fact finding would be needed and perhaps the family didn't want that? I'd have to know. I recently lost a friend to pancreatic cancer. It had been present for years.
I am taking Wegovy but actually want the anti inflammatory benefits more. I have RA. I would do anything to walk unaided again.
I spent twenty years on Steriods that caused a five stone weight gain.
I actually proved it to my consultant that three months on those bastards but three stone on me. It had nowhere to go on a overweight but not obese person.
Many illnesses are treated with steriods because they are cheap. Not all illness is self inflicted. Cancer drugs also make people put on weight.
I think the chance for obese people to cut the abuse they suffer is what's making these options worth the risks.
Slim priveledge is real not a journalist's made up idea.

thisiswheretheseagullfliesaway · 08/11/2024 14:40

I've been waiting four years for surgery I started off at 7.5 stone. It turned out two of those years I'd been taken off the list in error. After the four years I ended up 16 stone by then I was too fat to operate on.

I have NF1, scoliosis, dural ectasia, pcos, adenomyosis, endometriosis and pernicious anemia and chronic anemia. My very bulky womb is being crushed by my deformed deformed pelvis it's excruciating and I often feel strong contractions as if I'm in labour. It's not always a simple as eating less and moving more. I regularly faint due to extreme blood loss which makes exercising the tiniest bit tricky.

For me the injections have been a literal life saver. I'm losing very slowly at around .5 to a 1 lb a week but it's going down. Three months in I've lost a stone. I'm getting my surgery early next year and I can begin to live again. It's a tool to help me which wouldn't be needed if the NHS hadn't have messed up.

As I said previously my stomach lining bled due to two aspirin it was so severe I almost died yet you can buy aspirin in the garage for a quid. Aspirin for my mum and thousand like her is a life saver and helps her stay alive.

FlappingMadly · 08/11/2024 14:42

I’m very sad for this poor lady and her family. Do we have all the facts? Presumably she was on 2.5. It seems very sudden.
When I was in the process of ordering the side effects mild snd severe were made clear - you had to click to show you’d read them. And then a leaflet with the pen when it arrives.

SilenceInside · 08/11/2024 14:43

@Anonymousess of course it's important to look at anyone who has died whilst taking Mounjaro or Wegovy. But the report is from the death certificate, not an inquest. We don't know anything else about this woman's medical history. It's far too little information to be making any definitive statements about additional risks of using these medications.

taxguru · 08/11/2024 14:48

CustardCreams2 · 08/11/2024 14:21

It’s true that obesity is a lifestyle choice, not a disease. There are actually vanishingly few medical conditions that cause obesity, especially when said conditions are treated. But again, they are actually incredibly rare. People need to eat less calories that is all.

Speaking as someone who has been morbidly obese for most of my life, I fully agree. My weight, as an adult, have fluctuated up and down many times between 13 and 25 stones. Weight increased due to over-eating, bingeing and lack of exercise every single time, due to busy lifestyle, stress, etc., but still over eating and lack of exercise for whatever underlying cause. Whenever I exercise more, eat more healthily, etc., I lose weight. Currently at my lowest for 40 years! That has been after many years of generally being more active, not bingeing too often, and making a conscious effort to eat smaller portions and be more mindful of what I was eating. None of it is easy. It's hard to make yourself walk 10,000 steps on a rainy day when you're stressed with work, a parent with dementia and a husband with cancer, but you just have to make yourself do it.