Death linked to Mounjaro

[suki1964]

https://www.bbc.co.uk/news/articles/cz6jg6nw2zeo

I am in no way knocking anyone who is using these drugs, seriously if I could use them I would. However Im throwing this up here because these drugs have only been tested and deemed safe on a small study - those who's BMI is above 30.

@CocoDC That’s great, as you say, not everyone gets side effects from taking a medication so many ppl will have your experience.

In your opinion, what’s making MJ so effective for you? You already have a healthy, active lifestyle -does it improve auto immune conditions? We have auto immune conditions in my family so I’m curious.

In knots if laughter that @CustardCreams2 could possibly be a doctor.

Science-free and ignorant

Hilariously foolish statements

Nope you are not in medicine

From an actual medical consultant of many, many years

Even this one
Looking for 'medical conditions that caused obesity' like this would mean something

This goady poster is most certainly not in medicine!

@BruFord the drugs reduce inflammation and have been shown to help autoimmune disease such as RA.

The next big study is dementia.

That’s the issue.

Some people can’t make themselves just do it.

It’s amazing that you can. It’s great for you. But because you can it doesn’t mean everyone else can.

Binging less isn’t just something a lot of people can just do. It’s the equivalent of telling someone with anorexia ‘you just need to eat more. I was underweight and managed to just eat more so you can’

Even if they aren’t stressed with work, have a parent with dementia and a husband with cancer, they will likely have other things going on. Some people need the additional help to get to the place where they can eat less and move more.

No 2 people are the same. Even if they appear to be struggling with the same issues.

@Searchingforthelight@Searchingforthelight therapist, perhaps?

My medical PhD DD always has a good chuckle on that one.

@Mrsredlipstick If they also provide relief to rheumatoid arthritis sufferers, that would be amazing. My Mum suffered from RA (not weight-related, she was too thin tbh) and I dread being prone to it myself. It’s a horrible disease.

All of this is spot on

I want to add that the individual may have absolutely no additional stressors whatsoever, nothing additional going on in the background
No stressful job, difficult home life, parents with dementia or what have you

Some people (evidently, many people) simply need assistance to stop overeating

It's wonderful that this is now possible and many more people will regain their health

I look forward to it being available more widely within our NHS

It's really interesting, isn't it, and exciting to think of what the future will hold

Semaglutide was studied in mild cognitive disorder and mild Alzheimer's a few years back, before the ozempic rush. It's really interesting to see how this all pans out in years to come...

“You do realise that most people taking MJ are now able to eat less and move more, because they are taking MJ? It’s not a miracle drug. It doesn’t melt the fat with no effort. It helps people be able to move more and eat less. Consistently to improve their health.”

Rubbish - if this were true, you wouldn’t have celebrities in their droves parading their new bodies or people clambering to take this drug and defend it to the hilt, regardless of the safety concerns, as proved on this thread.

This drug is an easy option, reduces appetite (which certainly in some users causes even more unhealthy habits - you only have to read the posts on here of users surviving on next to nothing for days through lack of appetite caused by the drugs), and god knows what’s going to happen to the thousand of users in years to come who either can’t afford to pay anymore or the side effects become too great to stay on long term, when the weight just comes straight back on.

The argument that all drugs have risks and adverse side effects just don’t add up. I take several drugs to keep me alive everyday, I have no choice about this. These drugs treat illnesses that have nothing to do with lifestyle and I have to accept those risks because I’m between a rock and a hard place.

Taking a drug for weight loss that can cause death is just crazy and no different to going under the knife for plastic surgery. Of course being obese has health risks but this is through lifestyle choices which can be reversed with healthy choices and lifestyle changes, but losing weight and keeping it off is bloody hard work and takes time and effort and consistency but not anymore when there’s a wld to be had! And some posters on this thread clearly have their fingers in their ears singing Lala when it comes to the risks of these drugs.

Don't let scientific and medical get in the way of your daft rant!

Happy jabbing everyone- enjoy regaining your health

Ignore the ignorant like this poster

I feel like it has virtually cured my psoriatic arthritis.

It hasn't of course, but it's reduced pain and inflammation to the point that my joints feel and look normal. It has helped more than any of the horrible and quite dangerous immosuppresant drugs have been on.

It has also lowered my border line high blood pressure to the very healthy zone. And that was immediately, before I even lost any weight.

Oh and I am slim now all without a single dastardly side effect.

There are heart disease, strokes and dementia in my family tree and it has positive effects on all of these.

I would take it forever if I could.

@Finnulafishface nonsense, all of what you say. It's not a quick fix, it takes time and it takes a calorie deficit as with any other weight loss programme. The risk of regain is the same as any other weight loss programme.

I will be taking the injections for probably a year, to reach a healthy weight. That will take hard work, consistency and effort, which the injections will assist with. I am well aware of the risks, having done the obvious die diligence before making a decision about my health and my future. This one story does not change those risks.

@Smallsalt Yes, several drugs have been repurposed to treat diseases other than those that they were originally designed for. Tamoxifen, used to treat certain types of breast cancer, is one example.

If weight-loss drugs reduce inflammation and autoimmune conditions, they might be tweaked to target those conditions, which would be wonderful. RA and other forms of arthritis can strike anyone, regardless of their weight.

Nonsense, everything you do in life involves risk. A lot of those things could be done in a safer, but harder way.

Why would you ever drive anywhere when walking would probably be statistically safer? Why go on holiday, it would be much safer to stay at home? Life is not risk free. People that use Mounjaro, myself included, are willing to take the very small risk for greater benefit.

I'm very sad for this lady and her family, she only wanted to lose weight, as soon as I saw the news I knew that it would be jumped on and used as another stick to beat us with.

This type of ridiculous poster like @Finnulafishface fail to understand the scientific and medical evidence

They also haven't grasped that all of us taking WLI have capacity to consent to our own treatment
Part of that capacity is weighing up the risks versus the benefits

Why aren't they just as worried about, as a random example, gastric bleeds due to NSAIDS?

These meds have the ability to dramatically improve our nations health

Those who resent other people regaining their health are simply a nasty bunch

Happy jabbing, everyone!

@Finnulafishface
There are a number of doctors on here, none are WLD bashing.
As I said previously cancer drugs and steriods will increase body weight. Did you miss that? Please Google.
Fat shaming is disgusting however I hope you never develop a life threatening illness where you have to be treated with these drugs. They are horrific.

Taking a drug for weight loss that can cause death is just crazy and no different to going under the knife for plastic surgery.

You won’t like to hear I’ve had plastic surgery too then 🫢

It's very sad she has died

But

There are risks and possible side effects attached to every medicine

But there is no proof that it was mounjuro that caused /contributed of what happened her death

It is up to the person taking them to decide if worth the very small risk

2.5 is a starter dose and minuscule in the theme of things compared to 15

Oh are most people taking it celebrities?

Or are most people taking normal people who are obese?

Why would I be referencing celebrities in that post? What do they have to do with anything? Are you suggesting it shouldn’t be available because of celebrities.

What do you think will happen to users in future? You sound like the ‘everyone who takes the Covid vaccine will be dead in 18 months’ type person.
Maybe they will get cheaper? Or be able to get on an nhs prescription so more people can afford them and afford to stay on them should they need to. That will really piss people off won’t it. Being able to get it for the price of an nhs prescription. Overweight people taking up appointments for their check ins.

What do you believe the long term side effects will be? And what’s your basis?

It’s not a quick fix. And when people say that it proves they have no clue. Do you realise these drugs are also saving some people’s lives? Do you believe people taking antidepressants are just taking the quick fix?

You are entitled to your own opinions but it’s only an opinion, it’s not based on facts. It’s based on your own annoyed at obese people. can I ask why you spend so much time reading these boards to know what people are doing if you disagree with it?

No one has their fingers in their ears. We know the risks and benefits, far better than people like you.

Yawn. Same old nonsense.
And it’s not like any of the just move more and eat less - simples - brigade have any concern for us fatties taking mounjaro. It’s judgement but not concern for our health. Please just ignore the ones who like to wind up. They are enjoying it.

I saw this the other day- 3 year long trial data outcomes presented at an obesity conference.

In patients with pre diabetes, 13% of the placebo group went on to develop diabetes. In the group treated with mounjaro/tirzepatide, only 1.2% did.

95% of participants reverted from pre diabetes to normal blood glucose levels.

This is game changing in relation to preventing diabetes - one of the top 10 leading causes of death and amputations in the world

The experts are

Ooops posted too soon. Experts in the field know that obesity is a disease, and impacted by much more than just calories in calories out. I'm not talking about someone who just wants to loose 5-10 pounds. Actual sustained obesity is a chronic condition.

I agree about the unhealthy habits taking injectables makes you have. Agree that I’ve read several things about having so little appetite or feeling so sick you can’t eat. Look at Sharon osbourne. She says it’s messed her metabolism and she Can’t put weight on now. Loads of celebs look awful on it too. Scott disick looks bloody awful.

it’s not normal.

I reckon worst case we will discover these drugs are not what we think they are in 10-20 years, maybe causing more serious issues, like death and goodness knows what else. Maybe mental health issues or bone issues from lack of nutrition.

best case, we are opening ourselves up to more disordered eating, actual eating disorders, and a bunch of young people that can’t be arsed to educate themselves about diet/exercise because there’s a pill for that.

apart from some medication and some illnesses, being overweight is mostly a lifestyle choice.

And actually I think we still have an issue re education. People say “oh but I ate no calories and gained a pound”… lying to themselves…. It’s basic maths. I think people underestimate what they eat and forget to count things like drinks. They say things like “I just had a bowl of special k this morning” but actually that large bowl was a few hundred cals. 30g of cereal is teeny when you weigh it. I actually need to eat around 1200 cals a day to see the scale move. I’m perimenopausal and short.

Some more cautious people could say that pharma made obesity a “disease” so that it could “treat it” and ultimately make money. Lots of money.