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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Death linked to Mounjaro

412 replies

suki1964 · 08/11/2024 01:18

https://www.bbc.co.uk/news/articles/cz6jg6nw2zeo

I am in no way knocking anyone who is using these drugs, seriously if I could use them I would. However Im throwing this up here because these drugs have only been tested and deemed safe on a small study - those who's BMI is above 30.

Susan McGowan looks into the camera smiling - she has blonde hair in a short bob, black-rimmed glasses and a light grey t-shirt

Nurse's death linked to weight-loss drug Mounjaro approved on NHS

Susan McGowan from North Lanarkshire died two weeks after taking the drug tirzepatide, brand name Mounjaro.

https://www.bbc.co.uk/news/articles/cz6jg6nw2zeo

OP posts:
Thread gallery
10
Novjaro · 10/11/2024 14:16

To all the naysayers and the ones saying obesity is a life choice, just get a grip. You’re probably the ones shoving fillers and Botox in your faces etc but I don’t care or judge because what you do with your body is literally none of my business. And vice versa.

Shrinkingapple · 10/11/2024 19:40

Sorry if this has been said before but I've been hearing that it isnt the mounjaro itself but the quick weight loss that comes with it.
This lady was only on her 2nd dose so surely isn't true for her ?

CustardCreams2 · 10/11/2024 19:47

This reply has been deleted

Message deleted by MNHQ. Here's a link to our Talk Guidelines.

IrisPallida · 10/11/2024 19:56

This reply has been deleted

Message deleted by MNHQ. Here's a link to our Talk Guidelines.

Please do 'attest'. What was your role in the trials exactly? Which country were you working in?

How old were you when the drug was first prescribed?

CustardCreams2 · 10/11/2024 20:00

I’m a uk qualified doctor working in the uk.

CustardCreams2 · 10/11/2024 20:00

I’m leaving this nasty thread.

SilenceInside · 10/11/2024 20:08

@Shrinkingapple I don't know what the "it" is that you're referring to? "It isn't the Mounjaro itself but the quick weight loss..." What is it that you're referring to?

IrisPallida · 10/11/2024 20:08

CustardCreams2 · 10/11/2024 20:00

I’m a uk qualified doctor working in the uk.

Lol. So you cannot attest, and you have no actual knowledge of the clinical trials...

MissCeltic · 10/11/2024 20:13

I can understand why people are worried but you just have to weigh up the risks. Pancreatitis is a rare side effect but a bigger side effect of obesity is stroke, heart attack etc.I would say more people will die of obesity rather than because they are on Mounjaro.

Wednesdaysdrag · 10/11/2024 20:22

CustardCreams2 · 10/11/2024 20:00

I’m leaving this nasty thread.

Really?

What was in the comment that got deleted?

Who is nasty? Was it you?

Shrinkingapple · 10/11/2024 20:41

@SilenceInside Pancreatitis

Jimmyneutronsforehead · 10/11/2024 20:46

Shrinkingapple · 10/11/2024 19:40

Sorry if this has been said before but I've been hearing that it isnt the mounjaro itself but the quick weight loss that comes with it.
This lady was only on her 2nd dose so surely isn't true for her ?

Mounjaro can affect the pancreas as it directly affects insulin regulation so can play more of an active role in the function or dysfunction of the organ. I don't think this should be denied and should be available information so users can make a fully informed decision about the medication they use.

It can also exacerbate asymptomatic pre existing pancreatitis. For example, my partner was admitted to hospital after his second dose of 2.5mg mounjaro for pancreatitis and he was told to stop taking this forever as well as anti-inflammatory drugs unless under close medical supervision but due to a long history of alcohol misuse in his younger years, it was coined that he has probably had a low, pre-existing pancreas inflammation that was made worse by the medication. This was treated on both an inpatient and outpatient basis.

Weightloss in general affects the gallbladder and pancreas and can lead to gallstones which again block the ducts to the pancreas.

Obesity can also lead to pancreas related illness as well as every other organ.

Because there are different kinds of pancreatitis, such as acute, alcohol induced, gallstones related, and chronic, and in some cases it can remain asymptomatic, then in the case of the nurse who has passed away I don't think it's incorrect to document that the medication was a contributing factor but unless she had her pancreas function checked prior to starting this medication, which is unlikely as it doesn't require these checks in the UK, then I don't think it's safe to say for sure that this was the sole cause of her pancreatitis.

GreyMember · 11/11/2024 12:32

Stop eating refined carbohydrates and your hunger will disappear because your body's natural signals will be restored. It is also very difficult to put on weight if you don't eat refined carbohydrates. You will also have an improved mood as refined carbs also dysregulate serotonin.

I warned against the extreme dangers of this medication some months ago. You need to understand that there is no long term data on this medication and just because you aren't dropping dead of multiple organ failure right away does not mean you are safe.

Stop fetishizing food and eat as you evolved to eat. I know it can be hard given that there is an entire industry around it but you have to. Big pharma loves obese people, it makes trillions from selling drugs for all of your ailments. Many of them (BP medications for example) do nothing aside from artificially bringing health markers down which long term do not even increase your lifespan.

GreyMember · 11/11/2024 12:41

And by the way, you cannot compare the risk of obesity to the risk of taking this weight loss injection because there is no long term data on the risk of injection.

Wednesdaysdrag · 11/11/2024 12:52

Can you stop lecturing people about something you have no clue of empathy about.

What do you mean you warned people? The companies who make it and the medical experts have been very explicit about the risks. Why would you need to warn people?

Why is there an assumption that people simply don’t understand? Rather than they don’t agree with your personal opinion.

and one who says things like ‘stop fetishising food’ or ‘stop eating simple carbs’ someone who is clued up on addictions problems or the complexity of the problem. And that’s fine to not understand. But I don’t know why some people seem to think they know more than someone actually taking it, more than people’s actual doctors (many of us have discussed with our doctors) and keep insist on sharing their derogatory opinions of people.

I really wonder if people do this to alcoholics, drug addicts, people with Anorexia on MN. It’s not actually helpful.

ViolaPlains · 11/11/2024 13:47

I'm not sure what the real point of this thread is and the real motivation behind starting it and then not engaging.

I've been taking Mounjaro since May. I think that at some point in the future a version of a weight loss drug will be in the water supply like fluoride.

SunQueen24 · 11/11/2024 13:59

I warned against the extreme dangers of this medication some months ago

To diabetics or just for weightloss? Because presumably the risk factors remain the same irrespective of the intended outcome.

@GreyMember

SunQueen24 · 11/11/2024 14:14

GreyMember · 11/11/2024 12:41

And by the way, you cannot compare the risk of obesity to the risk of taking this weight loss injection because there is no long term data on the risk of injection.

ahh so the doctors and scientists involved are doing this in error, are they?

Jimmyneutronsforehead · 11/11/2024 14:14

GreyMember · 11/11/2024 12:32

Stop eating refined carbohydrates and your hunger will disappear because your body's natural signals will be restored. It is also very difficult to put on weight if you don't eat refined carbohydrates. You will also have an improved mood as refined carbs also dysregulate serotonin.

I warned against the extreme dangers of this medication some months ago. You need to understand that there is no long term data on this medication and just because you aren't dropping dead of multiple organ failure right away does not mean you are safe.

Stop fetishizing food and eat as you evolved to eat. I know it can be hard given that there is an entire industry around it but you have to. Big pharma loves obese people, it makes trillions from selling drugs for all of your ailments. Many of them (BP medications for example) do nothing aside from artificially bringing health markers down which long term do not even increase your lifespan.

Edited

Thanks, you've cured me.

On a realistic note I'd love you to point me towards your linkedin page or other professional portfolio that makes you qualified to warn people of the risks, more so than the medical prescribers that actually do promote the risks and benefits to patients in order to make an informed decision.

To say food is fetishised is a huge, incorrect generalisation and oversimplification of long since recognised disease. It completely ignores medical background, poverty, socioeconomics, food availability etc.

There are many reasons why ghrelin and glp-1 may be disrupted in someone who is obese and whilst simple carbs can impact on blood sugars it's very dismissive of all of the other reasons that these hormones can be disrupted which then leads to obesity.

As soon as someone pushes the anti-pharma rhetoric they've lost their side of argument. There is money involved. We live in a capitalist society. It will always pay because obesity will always be a problem because as I mentioned before there are so many reasons that aren't just simple carbs for why people end up obese, but that doesn't negate the beneficial life changing impact these medications have.

I hope you don't take paracetamol because big pharma know they can always make money off people who have headaches. It can damage your liver so better not, eh. I mean people take it all the time and it's so easy to be misused because you can pick it up at your local pharmacy, and is really easy to accidentally overdose on.

Come on, be for real.

artificially bringing health markers down which long term do not even increase your lifespan.

Please please go do some research about how the metabolism works.

Are you saying we should stay fat? What are you getting at?

I think if you assume that people are only taking this medication to increase their lifespan and not really the quality of life that they have now then this is just a further demonstration that you don't really understand obesity.

For a lot of us, the organ damage is done. We're preventing it getting worse. Except we do know that actually these medications have a positive long term impact on cardiovascular health, inflammation, autoimmunity, visceral fat and liver function, and therefore we can compare this medication to remaining obese because remaining obese does not positively benefit any of this.

We should always collect new data and it should be peer reviewed. To pretend that this is a new medication that has not already been extensively safety tested, albeit in the diabetic population, is full on head in sand. There is no evidence that shows that the risks are higher for obese people outside of the diabetic population.

If you are obese and you don't want to take these drugs then you do not have to do it.

Those of us who are taking these drugs are well aware of the clinical data available, we're aware of the age of this drug and how long it's been introduced into this population of people, we're aware of the risks to us if we remain obese and we're aware of the astronomical costs of private prescriptions for this medication.

Thanks for warning us months ago though I guess. Certainly not patronising us at all.

NoTouch · 11/11/2024 14:18

ViolaPlains · 11/11/2024 13:47

I'm not sure what the real point of this thread is and the real motivation behind starting it and then not engaging.

I've been taking Mounjaro since May. I think that at some point in the future a version of a weight loss drug will be in the water supply like fluoride.

Can you imagine we currently did not have water fluoridation and they wanted to add it to the water now? There is no way it would be approved.

Not sure if you are joking, but weightloss drugs in the water supply will never happen!

ViolaPlains · 11/11/2024 14:42

NoTouch · 11/11/2024 14:18

Can you imagine we currently did not have water fluoridation and they wanted to add it to the water now? There is no way it would be approved.

Not sure if you are joking, but weightloss drugs in the water supply will never happen!

I’m totally serious - I don’t mean any time soon or with these drugs but some distant iteration. I genuinely think this is a turning point for obesity.

NoTouch · 11/11/2024 14:53

ViolaPlains · 11/11/2024 14:42

I’m totally serious - I don’t mean any time soon or with these drugs but some distant iteration. I genuinely think this is a turning point for obesity.

And what about the impact on 60-70% of the population that are not obese? Or the elderly that it would be dangerous to lose weight? Or babies and children? Or animals?

They all also drink water!

These drugs are a turning point for obesity, but never in public water.

SilenceInside · 11/11/2024 14:57

It's science fiction, it's not a serious idea worth debating. A more realistic future is one where the NHS can prescribe injections for anyone who needs them at prescription rates, so free for those that qualify.

Gruttenberg · 11/11/2024 15:37

MrsTerryPratchett · 08/11/2024 04:19

It's a personal decision.

Sort of.

I'm of the opinion that healthcare shouldn't be a business. No advertising, no insta-people, no discount codes. I think risk should be discussed with an actual HCP whose job is your health, and public health, not profit.

It makes me very uncomfortable to see the discounts and online pharmacies. I've had very important discussions with HCPs about whether or not to take various medications, for various medical issues, all of which are a balance with me and the HCP talking about risk, side effects, benefits, LT and SH gain and loss.

What's happening right now is not that.

I agree that healthcare shouldn't be a business. Unfortunately we're forced down the route of buying online, which is a risky business for those who are faking being heavier than they are. You could send a photo of anyone with a vague resemblance to a passport or driving license photo. I'd still pay but would much prefer the profits to be made by our GP surgeries in exchange for having properly administered prescriptions that would be nigh on impossible for anyone below the limits to get their hands on.