Death linked to Mounjaro

[suki1964]

https://www.bbc.co.uk/news/articles/cz6jg6nw2zeo

I am in no way knocking anyone who is using these drugs, seriously if I could use them I would. However Im throwing this up here because these drugs have only been tested and deemed safe on a small study - those who's BMI is above 30.

@zaffa The most interesting part of Frogget is that she is so keen that eat less and move more is the right answer but then openly admits that despite moving more and eating less herself she is not able to sustain a healthy weight and lose her own excess weight. 🤷‍♀️

Yes, as quite a few (or the same people?) naysayers have mentioned on other WLI threads. You'd think people would practice what they preach first.

I love your positivity and how you end your posts with Happy Jabbing! 😊

I agree with everything you have posted, as a 20 year experienced Biomedical Scientist Team Manager in Histopathology, I know how much the NHS is struggling with sheer workload increases. Ours has increased 33% in 2 years, yet we have strict budget constraints against hiring extra staff, even with labour elected we haven't had any extra staffing budget so far and our staff are very stressed and have frequent burnout, I regularly do benchwork as a manager rather than my management job, because of inadequate staffing and the impact on staff.

Obesity contributes to increased heart conditions, cancer, diabetes and the list goes on, which leads to a lot more workload, especially for pathology labs, so I welcome measures to reduce obesity and other pathologies, especially cancer.

I have been on mounjaro for 6 weeks myself, after I tried the body coach HIIT workouts for 6 weeks solid and lost 2kg. But I ended up eating a lot more food as it made me constantly hungry, due to burning more calories. I am also out of the house 12 hours a day due to work and commuting 80 miles a day, so found a rigorous exercise plan was difficult to maintain long term. I am prediabetic so mounjaro has really helped with reducing my abdominal fat, which exercise didn't do, and insulin resistance and curbing my constant hunger. I also have diabetes in my immediate family and due to my ethnicity, my BMI of 31 was much higher than the 27 BMI recommended for someone like myself for mounjaro prescription. I am now 29 bmi and no longer obese, but need to get down to 24 ideally.

As sad as it is to hear about users who react severely, and the recent nurse death, there is always a risk with any medication and when we fill in the forms for any medication, it is important to be honest and list any health conditions, as there are many contraindications for other medication use and mounjaro like any drug, can exacerbate certain health conditions.
We don't know the clinical history of the lady who passed away, nor do we know if she severely reacted to the drug or had an infection etc. There have also been cases of severe reactions and deaths implicated with the covid jab and any medication including routine painkillers.

Unfortunately this is the risk we take when we decide to put anything in our body and all drug clinical trials include many observed known side effects.

Some people can criticise others for using mounjaro, but we all have free choice and know the risks we are taking and the posters on here criticising and judging others for mounjaro shows serious character flaws of the acting out of a negative, unhappy person.

Well said @mysticmaiden2024 and I agree with the HAPPY JABBING from @Searchingforthelight ! It actually just makes me laugh especially as I know it must make the 'cult of doom-mongers' seethe.

Brilliant and informative post

@Wednesdaysdrag What is the point of parodying what I have said?
It isn't really worth continuing to post when whatever is said is systematically re-interpreted for the purposes of making it seem as unreasonable as possible.

Regarding laxative abuse, I did in fact respond to a post about that recently. It was a woman with a history of laxative abuse who had recently bought a new supply and was wondering whether to start using it or buy some weight loss injections instead. As I recall, several people came on to the thread telling her that WLI were a way forward for her, even though her bmi was only something like 26. Fortunately the thread was moved out of the WLI area into the disordered eating part of the site.

I wouldn't dream of posting anything at all on the support threads set up by and for people using WLI. But this is a thread started for discussion of concerns around the drugs - which can't be that unreasonable since the regulatory body with which online pharmacies must register is expressing its own concerns and devising new safeguards.

Parodying?

You posted about people seeming to have a victim mentally and tried to convince us it was compassionate concern. Tried to convince people it wasn’t judgment. It was compassion.

I have posted plenty of things from the thread that were judgements out and out judgement. But it’s clear you haven’t actually read the thread. So how did you come to your conclusion?

Thats thread is someone abusing laxatives. Not using them correctly. And you are being hugely misleading with your summary of that thread. So would you, if someone is taking them appropriately and being told they are harming women and children, are likely killing themselves, shouldn’t take them at all because other people have been harmed think that was good advice? Would you them people making those comments were compassionately concerned?

I have linked the thread here so people can actually read it.

www.mumsnet.com/talk/eating_disorders/5199262-please-dont-judge-weight-loss-jab-prescription-previous-ed?reply=139439126

@ReadWithScepticism just to clarify that thread says her bmi was 32, not 26 so yes actually she would be suitable if bmi was the only factor to consider.
HOWEVER WLI are not suitable for people with a history of an ED. The prescribers screen for it.
If people commit fraud to purchase this medicine by lying about their history, that is on them. But the prescriber writes to your GP, who would provide additional context and prevent prescribing.

The offensiveness of many people who are totally ill informed is off the scale..... So what do you expect?

My GP is on it.
The "concerned" pseudo experts on this thread whose interest in adverse drug reactions seems to be restricted to Mounjaro, a drug they don't take, should probably be giving her a good talking to.

We can only go on what we know at the time and there simply is not enough evidence or data in the long term about these drugs and the effect on non diabetic, normal sized individuals.

I mean at one point in time we thought talc was safe, smoking was good for you and thalidomide was a great cure for morning sickness.

I personally think taking this drug would slip me into disordered eating. It messes up your bowels anyway which sounds horrific. And I've read that some people are not eating much at all on it as they feel so sick. How do they get nutrients? Are they getting enough? Is there any data on that?

The fuss on this thread is because there isn't really a drug like this. We dont have post after post about trying to obtain statins or chemo do we?

I'd like to see it regulated to only people with huge BMI and only prescribed by a GP in person. And possibly in conjunction with diet and exercise advice.

Well I for one am very glad it's not up to you @Froggerz

The stupidity of mentioning talc, smoking and thalidomide is startling. None of those went through the appropriate research and trials and indeed the thalidomide scandal is exactly why drugs now go through much more rigorous testing regimes and monitoring that in previous decades.

This board reminds me of the political boards where people who have differing opinions are called stupid and their intelligence is mocked. Is that all you have?! I've seen no counter argument that is even a little bit sensible.

and only prescribed by a GP in person

So no one would be on it then. GPs to not have the time for this. Unless you mean people should pay non-NHS fees to see a GP, have private blood tests, pay for private prescriptions every month. On top of the hundreds of pounds per month for the actual medication. That will just make it financially impossible for many people whose lives would be saved. All because some people lie to suit themselves.

There tons of studies on people. Why would they do loads of studies on people it’s not designed for.

The woman in this story did have a high BMI. So how is normal sized people taking it relevant?

and most people taking it are not normal sized. They do have huge BMIs. So you now agree its restrictions are correct and it’s actually fine.

It’s is regulated for people with a BMI that will impact their health.

There’s lots of people that can prescribe all sorts of different medications. Why a GP precisely?

My GP prescribed me anti depressants without seeing me in person. The one I had, also had pancreatitis as a side effect. I actually arranged the phone call to discuss help with my weight. I was given antidepressants. No help with my weight. So do you think the whole thing should be overhauled. Only GPs can prescribe anything and everything needs an in person meeting?

Because that’s simply not going to happen.

I mean don’t get me wrong. I would be happy for the GP to prescribe it and have a monthly appointment. It would mean I saved money. And actually saw my gp face to face.

I am not against it. I just don’t think it will happen

@Froggerz I am saying your argument is stupid not that you are. I then went on to explain why it's a stupid argument quite clearly,

Laughing at the idea of GPs fitting in thousands of people every month for Mounjaro reviews.

How is this a cautionary tale? The woman had pancreatitis. The MJ is hardly the thing that did it.
she took 2 weeks worth of medication on the lowest possible dose of 2.5 mg which is not even therapeutic. She wasn’t messing with doses.
Just bad luck I guess, which is very very sad. However, she must have had other issues too or didn’t seek medical attention immediately in case she experienced any serious adverse effects.

But again why? You've decided it's not for you, that's your choice.
Why are you so obsessed with what other people are doing, given you are clear you don't want to?
And why are you concerned that 'normal sized' (I assume you mean healthy BMi here) people are taking it, when it is prescribed at an above healthy BMI?

I haven’t seen one valid point about why people are so ‘concerned’ about it.

Theres been lots of sensible counter arguments. It appears you either haven’t read them or purposely ignored them.

I went back and read the OP and the poster said she would use WLD if she met the criteria. She has not posted again.
I have searched a little further and there doesn't seem to be a history of the poster having any issue with this medication.
I don't think the thread was intended to fat bash at all. One could even say it was reporting a rare issue.

People are lying about their bmi…lots of people

you can clearly still get it at normal bmi as people talk about maintenance doses etc.

im “concerned” because someone died.

does that help?

The person that died, wasn’t a normal weight.

So normal weight people lying to take it aren’t relevant.

Pancreatitis is already a known risk. And people have to weigh up the risks themselves. It’s also a risk of tons of other medications that are prescribed without a face to face Gp appointment or face to face monitoring. Or blood tests. Or anything.

People also lie to get lots of these medications too. Do we stop prescribing them all because people do this?

You didn’t answer if you thing all medication should be face to face GP appointment only.

Yes sometimes people die whilst taking prescription medication. Unless there’s an inquest we have no idea of all the contributing factors.

On the other hand it’s improving the health of many people and having a very positive impact for them. It’s the same with any medication. There’s risks and it’s deciding if the risks outweigh the benefits. And the medical experts have agreed that for people with bmi over 30 (or under 30 if there’s additional medical issues or you are of certain ethnicities) it’s has been decided the benefit outweighs the risk.

Why do you believe you know better?

People are committing fraud. Just like when they may ring up the GP having made up pain so they can get prescription painkillers. That is on them. Those people need to take accountability. It doesn't mean the medication is at fault, it means that people are abusing it - much like any other drug user abuses a drug.
Drug and prescription medication abuse is a whole separate issue that needs to be invested in by the NHS and addressed.
It is incredibly sad that someone has died. i will leave it to the experts to determine what impact that terribly sad event has on the safety profile of this or any other medication. surely you would rather hear from an expert on this matter?

Do you not realise that even if this lady had sat in front of a GP and been prescribed it, it wouldn't have changed anything? She qualified for injectables. She took it as she was supposed to. Online prescribing isn't what killed her.