My parents moved house when I was eighteen and off working abroad. I then returned and took up my uni place.
At the time, I felt very clearly that it was a rejection of me and my brother (they moved to a place which didn't have space for both of us, so very clearly saying "don't come back") I hated the new place they lived, didn't know anyone and didn't want to spend any time there. It was their decision, and I see their reasons. I hope they also understand my decisions as a result, ie: spending less time there.
The worst bit was that my parents seemed to want the best of both worlds -- for me to default to coming to theirs for holidays, christmas and birthdays like a child, but then "be an adult" when it suited them. So I would get guilt trips about "never coming home at the weekends" (why would I, it wasn't home) and the assumption was that I would come for all/most holidays and definitely christmas. They would make jolly jokes about me "turning up for a few weeks of getting my washing done and some decent food" as if I was unable to look after myself, but then in the same breath make it very clear that I wasn't to expect them to put a roof over my head when I finished studying because I was an adult now.
At the time, I found it very difficult, never considered their house home again, and even now find it annoying when my parents say things like "you're welcome to stay any time". The bit of me that's still 19 is like "You've changed your tune -- you couldn't get rid of me fast enough when I was young and didn't have any money".
Bottom line: make your decision. But be prepared for the impact, ie: your children will want to stay less.