I like trying niche scents but a lot of my most loved perfumes are designer - J’Adore, Mon Guerlain, Black Opium, some of the Margiela Replicas and various others over the years. Like others have said, I think designer scents are often easier for work. J’Adore is my perfect office scent.
Even with niche, I seem to like ‘easier’ niche brands like Gallivant. Brands like Etat Libre D’Orange scare me!