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November Lockdown: Mibbes Aye Mibbes Naw

990 replies

BlueThursday · 31/10/2020 17:06

Thread 3!!!!

OP posts:
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WouldBeGood · 16/11/2020 14:57

I don’t think the figures show that that’s where the spread is though

dementedpixie · 16/11/2020 14:59

The highest positive cases are not school age children. Unless its the teachers?

BlueThursday · 16/11/2020 15:58

Crikey how did we get here so soon? Has the new thread been created?

OP posts:
Judystilldreamsofhorses · 16/11/2020 15:59

I'm in FE, not a school, and teaching remotely, nut I read earlier about huge proportions of pupils being off due to either being infected or isolating.

www.bbc.co.uk/news/uk-scotland-54958552

I guess if wee Johnny goes to school, and sits next to wee Jimmy who is positive but asymptomatic, then comes home and sits next to granny...

Y0uCann0tBeSer10us · 16/11/2020 16:30

I'm getting a bit frustrated with the way the media are presenting antibodies==immunity (and conversely no antibodies==no immunity). I've done a bit of immunology in my time and its not the least bit surprising that antibodies wane over time because that's what they usually do - they are proteins (albeit robust ones) with a half life and its not a good use of a body's resources to constantly keep topping up antibodies to every virus you've been exposed to in your life, ever. With mild infections, you might not need to generate much of an antibody response in the first place. What your immune system does instead (once it's dealt with a particular virus) is create memory T and B cells that would allow you to quickly mount a response to said virus should you encounter it again, meaning it will probably be less severe second time around. Vaccines do a similar thing. Neither of these necessarily mean you can't pass on an infection, but the hope would be that yours would be less severe than it otherwise might be (which is presumably why the vulnerable groups are the priority).

It drives me crazy that antibodies are being used to calculate what proportion of the population has been exposed (or at least this is how its presented) as its scientific nonsense!

icanboogieboogiewoogie · 16/11/2020 16:33

That was really helpful @Y0uCann0tBeSer10us, thanks!

WouldBeGood · 16/11/2020 16:34

Yes, @Y0uCannotBeSerious, thanks. So interesting.

anon444877 · 16/11/2020 17:06

Definitely, I'd fallen for the whole 'vaccines won't last because covid antibodies fall away after 3 months'. Given how badly economic data is reported I don't know why I'm surprised science is suffering a similar mistranslation!

Y0uCann0tBeSer10us · 16/11/2020 17:23

@anon444877 the quality of science reporting and general data handling has me tearing my hair out!

MissEliza · 16/11/2020 17:25

@Y0uCann0tBeSer10us

I'm getting a bit frustrated with the way the media are presenting antibodies==immunity (and conversely no antibodies==no immunity). I've done a bit of immunology in my time and its not the least bit surprising that antibodies wane over time because that's what they usually do - they are proteins (albeit robust ones) with a half life and its not a good use of a body's resources to constantly keep topping up antibodies to every virus you've been exposed to in your life, ever. With mild infections, you might not need to generate much of an antibody response in the first place. What your immune system does instead (once it's dealt with a particular virus) is create memory T and B cells that would allow you to quickly mount a response to said virus should you encounter it again, meaning it will probably be less severe second time around. Vaccines do a similar thing. Neither of these necessarily mean you can't pass on an infection, but the hope would be that yours would be less severe than it otherwise might be (which is presumably why the vulnerable groups are the priority).

It drives me crazy that antibodies are being used to calculate what proportion of the population has been exposed (or at least this is how its presented) as its scientific nonsense!

Thank you so much for this explanation. Professor Sikora keeps talking about this on Twitter so it's good to know what T cells are.
Y0uCann0tBeSer10us · 16/11/2020 18:01

@MissEliza there are various kinds of T cells. I’m not sure which type Prof. Sikora is referring to, but in addition to memory cells you also have killer cells that are actively involved in clearing an infection by killing infected cells. A complementary branch of the immune response if you like which can sometimes be more important than the antibody response, but one that is almost entirely absent from main stream reporting on immunity.

MissEliza · 16/11/2020 20:13

That's a good enough explanation for an ignoramus like me!

WouldBeGood · 16/11/2020 21:16

That’s why i love these threads. Is there a new one?

icanboogieboogiewoogie · 16/11/2020 21:18

New thread:

Fears For Tiers www.mumsnet.com/Talk/scotsnet/4081317-Fears-For-Tiers

WouldBeGood · 16/11/2020 21:33

Thanks

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