From https://www.webmd.com/mental-health/addiction/cocaine-use-and-its-effects
"People who use cocaine often may also have more serious side effects and health problems, like:
Headaches
Convulsions and seizures
Heart disease, heart attack, and stroke
Mood problems
Sexual trouble
Lung damage
HIV or hepatitis if you inject it
Bowel decay if you swallow it
Loss of smell, nosebleeds, runny nose, and trouble swallowing, if you snort it
You may have strong cravings for the drug and the high it brings. But the more you use cocaine, the more your brain will adapt to it. You’ll need a stronger dose to feel the same high. This can lead to a dangerous addiction or overdose.
Stronger, more frequent doses can also cause long-term changes in your brain’s chemistry. Your body and mind begin to rely on the drug. This can make it harder for you to think, sleep, and recall things from memory. Your reaction time may be slower. And you’re at risk for more heart, stomach, and lung problems.
Giving up: Many people who are addicted to cocaine go through a phase called withdrawal when they first do this. Symptoms can include:
Depression
Anxiety
Fatigue
Trouble concentrating
Increased hunger
Cravings for the drug
Nightmares
Chills, nerve pain, muscle aches
A cocaine overdose is more difficult to treat. Physical signs include:
Increased sweating, body temperature, or heart rate
Trouble breathing
Chest pain
Nausea or vomiting
Confusion, seizures, tremors
Watch for these mental signs of overdose, too:
Anxiety
Panic
Paranoia
Hallucinations
Delirium
An overdose often leads to a stroke or heart attack. An ER doctor will test for those conditions and try to treat them first. They may also use medication to treat other complications you have."