Recurrent Miscarriage Support Thread 24 - tests, treatment, trying again.

[Brummiegirl15]

New thread for us if it's worked on phone! Will paste stats

Morgan my tests were all totally clear too and it's hard.

I'm 5 weeks today so hoping the cyclogest will do it's job.

Hi annie, I'm in Edinburgh. I thought from your username that you might be in Scotland
sounds like a good list as a starter. My understanding (which could be wrong!) is that the testing on the embryo would tell you about any chromosomal issues, including both translocations (which could be genetically passed down) and any of the main trisomies (mostly random) so if it came back normal then i think it's time to look at other causes. (Although as I am basing this on zero medical knowledge please do check its right).
The number of chromosomally normal embryos increases with increasing number of mc (as there is more likely to be a different cause), so i would definitely not stand for crap consultants speaking out of their arses. Glad you are going for the erpc and hopeful that you will get a result from the tests on the embryo. It may strengthen your case for looking at other causes.

Big hugs for getting through this weekend. Hope your dh is home with you now. X

annie I think your plan is a good one. I think often doctors do us a disservice by glossing over results, maybe to spare us a painful discussion, but it leaves us unclear what has actually been tested.
Karyotyping on you and DH would be done on a blood sample from each of you. In most cases any chromosome problems in the embryo wouldn't be passed on by one of you but arise spontaneously in the egg/sperm, or in the early stages of the embryo.
Testing on products of conception can mean two things. It's common for tissue to be tested ( histology - examined under microscope) to rule out molar pregnancy, less common to have cytogenetics or karyotyping of foetal tissues to establish if it was a chromosome defect or not. I think you need to clarify exactly what was tested and get a better answer than 'it was fine'.

morgan having no clear reason and therefore no clear plan is hard, even if it does leave you with a good chance of success. can you talk them into following the Coventry protocol for normal NK cells (progesterone from day 21 and heparin injections once you know sac is in the uterus)? aspirin with no diagnosed clotting defect is frowned upon by Coventry and St Mary's and can actually increase the MC rate.

Hi morgan, sorry the tests have not been able to find an answer. It's a horrible feeling to go again not knowing what is wrong. What nk testing did they do? I take it it wasn't unk? Would it be worth trying Coventry? Fwiw i also had horrendous hyperemesis /morning sickness with dd and don't feel i have a lack of progesterone yet have been diagnosed with high unk by Coventry and the treatment includes progesterone. I asked the prof about this and he said it may still help. Hope the private appt is more fruitful

congratulations longest and welcome to the world Beautiful Beth.

annie that's a very thorough list and I think you're doing all the right things, it's just a shame you're not getting the professional support you deserve. with regards to being Rhesus negative am I right in thinking you are given an anti d injection after a miscarriage?

twilight I second what everyone else is saying, sick leave for miscarriage is pregnancy related and shouldn't be counted.

I know how you're feeling towards work. I got a text message this morning saying 'when are you coming back'. it's quite handy having DH on the same team. He's reiterated again that I'm not coming back to do the same job, that I will be on medication prior to conception and the side effects of it. Apparently they were under the impression I just needed a bit of counselling! I'm trying really hard to get this idea of 'letting colleagues down' out of my head, it's not my fault they're short staffed. And I've had colleagues on restricted duties for, what I consider, much lesser reasons and they never felt bad about it so why do I?

Sorry to rant, just so pissed off with it all and a job I wanted to go for is going to come out next week so where do I stand if I'm being dealt with by occupational health. Miscarriage is ruining my life.

Hello to everyone, hope you're all as well as you can be and good luck to all the ladies with scans coming up

Just leaping in to give some good news before the champagne comes out. DP got a promotion and raise today, he is now a Director and for once we feel as though it's not all soon and gloom around here. It's a small company so I'm not sure what the patties will be but he thinks it could be around 10k. I'm so happy.

In other news I seem to be having creamy CM towards the end of my cycle which generally doesn't happen unless something exciting has happened. I'm not going to test as I just can't think it's possible right now but I feel a tiny tiny tiny small bit hopeful

*what the pay rise will be

Congratulations (on both counts) seb maybe the worm has turned for you!

That's fab news Sebs pleased you've had some good news for a change.

Keep us posted on anything else!!!

Annie, rh- won't cause mc AFAIK, but you may be given anti d after a mc, especially if you have had bleeding/surgery. I was given anti d numerous times in my 3rd trimester with Scott due to all the bleeds, and they can also test your blood to see whether you need it due to having the antibodies (can't remember the name of the test, sorry). As it turns out, Scott is also rh-, so dh must be a carrier in his recessive gene, so all those injections were for nothing But the issues come in later pg, so routine precautionary anti d wouldnt be given for RMC, except after it had happened to help protect you for next time. Apparently its not possible to give anti d to overdose levels, so there's no problem in multiple doses over time (I got it weekly at one point). I'd say, always mention your rh- status, but I wouldn't think its a cause.

Sebs

Wow great news Sebs - you were due a bit of good news :)

Laughed out loud at the shit a few pounds - I need to shit three stone before I get married...more if this pregnancy progresses.

Xx

I've become boring. Had to bail out of a VIP bar launch tonight as I'm so exhausted.

That is so unlike me. Hate how crap I feel and then feel guilty

longest massive congratulations. I hope you are all well. Xxx

Great news sebs, and you were definitely due some.

Tiredness is good brummie three Cheers for feeling crap!

Hi all.

Sorry to butt in and jump on here but March girl recommended it as we are both on another thread about the Response Research Trial.

Bit about me... I'm 31, ttc #1 since February 2014.
MMC in may 2015 at 11+6. Measured at 6+4.
Mmc in October at 9+5 measured around the same.
Mc in January at 5+2.

Referred to the rmc..first appointment at the end of April (after they cancelled the first without notifying me! ), bloods taken and came back clear. I signed up to the Response trial and I'm now on Cd28 of the our 1st cycle ttc since signing up for the trial, 2nd cycle since mc3.

Had bfn all week and have pretty much given up hope now that we've caught this cycle (currently 10-12 dpo). :( Feeling a little disheartened and finding these groups a great support!

Welcome kazz, nice to see you over this side

Thanks for the pointer! There's no way I can catch up with everyone on here!

Welcome Kazz, glad to joined us over here as well!

Sebs, congrats on dh's job news & let us know what happens on the other front ??

Brummie, sure you don't mind missing the vip event in the circumstances. What did you decide about this weekend's trip?

It's fine kazz, we don't expect you to catch up. We're on our 24th thread already! (Soon to be 25th). Things move pretty fast but there's a cheat sheet on page 1 (the second one on that page) that will help you work out who everyone is.

Hi there kaz - always sorry to hear of more newbies, but more than happy to lend an arm for support - sorry you are experiencing this in your life just now, maybe we can accompany you (and all of us) to a happy ending!

Longest Amazing!!!! Hope you're beaming from ear to ear and not too exhausted to appreciate cuddles!

twilight I can't believe your line manager , I'm sure they're not allowed to count it as sick leave. I had similar at my school.

Annie did they never suggest IUI? That's what I moved onto after my 6 rounds of clomid. It sounds like we've had some similar experiences. My first mc was after a clomid bfp and my second after an iui bfp. I've never managed a natural bfp though. I'm also RH- ( Snoopy they only need to give you the anti-d once the placenta has taken over, so with my early mc's I never had an injection). A further round of iui failed and then an ivf round. I've got two frosties of dubious quality waiting until I've got my nk cells results. I've got factor V leiden thrombophilia (diagnosed by the rmc after mc 2) but my consultant didn't think that was the cause of my mc's. I think my problems are more related to my uneven cycle - ov around cd21 then lp of 7 days.

Morgan I'm sorry you didn't get an answer . I know exactly what it's like to be told they can't find a reason.

Fingers crossed that wull be the case for everyone! :)

Hi kazz, welcome .

My Dad has got worse again. His chest is bad. The doctor is worried as it's still congested and hasn't responded to the antibiotics. He thinks it's aspiration so is putting him on diuretics and intravenious feed . I'm worried this is more to do with the MSA and he's losing more of his life . Going over to visit tomorrow.