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IVF cycle buddies June/July

441 replies

Hobbes39 · 30/05/2017 12:09

Hi! I'm hoping that this is 3rd time lucky for us... due to start process for my first Frozen transfer in June, with the actual transfer being in July... anyone want to join me on the journey? We have 2 unsuccessful fresh cycles behind us, and I have this one single little embryo from the last cycle sitting in the freezer waiting for me. It's a 3BB and all my hopes are pinned on it being the one!
We have unexplained secondary infertility, have a DS who will be 4 in August, and I've just turned 40, so time isn't on our side... so I'm now waiting for my period to start (due in about 10-14 days, although my cycles are mucked up since our ivf failed in April)... but once it comes i will be down regged to them do transfer early July I think! Fingers crossed we get lucky this time...!

OP posts:

Hopes2bmom · 14/06/2017 19:04

Hello Fox23,

Thank you and good to know you all! This gives so much of emotional support during this stressful phase, happy I got here, how is it going with you?


Fox23 · 14/06/2017 19:22

For me stress hasn't set in yet, or reality of it. So, I agree, this is a great place. Personally, besides my hubby, nobody knows I'm on this journey. It's to avoid disappointment. So, sometimes I feel like I'm losing it by keeping it in. What went wrong last time? You said this is your 2nd cycle?


79Karen · 14/06/2017 19:36

Hi Fox for me once we had an appointment at the fertility clinic everything seemed to move really quickly, but everything up to that point was so slow and long winded. Hopefully you can start soon.


Hopes2bmom · 14/06/2017 19:36

Exactly the same here! My hubby and I are only aware of all these, it's secret to the rest of the world. The clinic has not given the exact reason for the failure 😔 As I told you we have sperm issues and went in to icsi , out of 11 eggs 6 fertilised , 3 made it to blast and out of them they put back one very good top grade hatching blast in, based on age and the first attempt they only put one blast 😔unfortunately the other 2 were arrested at that stage and did not make to freeze. But nothing worked, bfn. They said it could be an implantation failure. This time around we did an endometrial biopsy (scratch) to make the layer more receptive and to fine if I have any anti immune issue, and dna fragmentation test for my husband , our results were pretty good, nothing to worry , they have asked me to take a steroid called prednisolone to suppress the anti immune cells a very less dose though. How nice it would be if the clinic can tell us the exact reason for the failure, they just work on probabilities after all our emotional / physical/ financial stress!


Fox23 · 14/06/2017 20:06

hopes2bmom - good luck tomorrow with your scan! You must feel beside yourself! I would be sooo anxious.

Karen- what's the latest with you? I'm just getting to know everybody. Sorry if I missed your previous posts.

My appointment is on 20th, next Tuesday. I already catch myself counting days. Silly really.


Ozzyboo · 14/06/2017 22:48

Welcome fox & hopes, & the biggest good luck to you both on your journey!
I am 29 and had one failed cycle which ended in chemical pregnancy in march. This group was such a great help to me as like you both, it's only really me & OH who know about it! Counting down the days is SO not silly.. I promise you, you are not the only one! I'm counting down the days till next AF (17 days) till I can call and start my 2nd round with one of my Frosties!
How is everyone else? Hope all those DR are getting on ok with injections x


Hopes2bmom · 15/06/2017 12:07

Went for a baseline scan on cd1 today, the scan was all good, the endometrium is lil thick than expected so then want me to bleed today and start my stims tomorrow, they want me to shed it with more bleed today. The blood works were also done, I would get the results in few hours, if all goes well, I'm all set to start stims tomorrow!!


79Karen · 15/06/2017 12:51

That's good news Hopes glad you managed to get some clarification from your clinic. Good luck for the stims stage.

Quick question, do you still carry on with the burserlin during stims?


Hopes2bmom · 15/06/2017 13:26

Hello Karen,
Thanks, yes I need to continue buserlin but reduce my dose, I am taking the nasal spray and not injections. I have been taking 2 sniffs 4 times a day , from tomyit will be 1 sniff 4 times a day, haveto continue till my next scan then I ll get to know when to stop.


geeup · 15/06/2017 13:42

Sorry am so behind on this thread! Yes you continue buserlin during stims. I didn't reduce dose either. Stayed the same.
No news from me. Am downregging and waiting for my breakthrough bleed. No sign so far but suspect it'll be late like last time...


79Karen · 15/06/2017 13:53

Hi Gee I'm the same though I've been told to finished by current course of the pill, last one today, so I expect AF will be here around the weekend? Have my baseline scan booked for 26th


Hopes2bmom · 15/06/2017 13:54

Hey gee up,
How far are you through the dr? I started spotting very light around 12 days post the buserlin commencement. Then got my full bleed yesterday.


geeup · 15/06/2017 14:09

I've only been downregging for 6 days so suspect it'll be quite a while till AF shows up! It may be even longer as my last cycle before this one was really long (40 something days!) after my failed IVF cycle and I either didn't ovulate or ovulated really late (around CD20) this time so god knows when I'll bleed. I'm not on the pill either so not sure if that would've helped.
It's so odd placing your entire hormonal system in the doctors hands!


LoPl · 15/06/2017 14:47

Gosh so many newbies. Hello Katherine, pumpkin James! Fox and Hopes2 and good luck!

I'm gearing up now for cycle 3. Had initial consultation yesterday with new clinic - and they agreed with my old clinic that I'm not mad to do another cycle despite my previous crappy results. Basically, my results are at odds with my stats (i.e. age, AMH levels, BMI). I'm taking this as a funny sort of good news.

So, Dr suggested doing a long protocol this time - think this means a nasal spray for about a week before AF shows up at. Does this sound right?


79Karen · 15/06/2017 15:40

Hi LoPI sorry if you've mentioned this before, if you don't mind me asking, what are your anomalies with your age, AMH and bmi?


LoPl · 15/06/2017 16:25

No props Karen. Its does sound rather cryptic reading it back.

I'm 37 with AMH 16.1 and healthy BMI. My first AFC was 17 and my second was 10. So basically, they would expect me to produce around 10 eggs at EC. I got 8 eggs (6 mature) on first go, so under the expectations but not awful. However, I only got one egg on the 2nd cycle... which really doesn't seem to stack up. Talked to three consultants about this now, who have all been surprised/perplexed by my low numbers. So, going again, with the hope that cycle 2 was just really shit luck. Dr this week did suggest I continue to take Co-Enzyme Q-10, as there are some studies suggest this may help. And they are trying long protocol to see if they can get more follicles to grow at consistent rate. Fingers crossed...


79Karen · 15/06/2017 18:23

Thanks -LoPI I wonder what happen with your 2nd cycle? I can see how you were left a bit confused by it all. Your numbers aren't dissimilar to mine and I'm on long protocol (1st cycle) i don't know what factors are used to determine protocol though? I've read a few things about Q-10 and I've got a supplement with a small amount in it, thought it wouldn't do any harm


Fox23 · 15/06/2017 18:36

Hi all, reading this makes me feel like a newbie in advanced language class!!! Lol
Good luck Hopes, fingers crossed Smile
Ladies, I admire your strength, sound like most of you are going through this 2nd or 3rd time!


Goodluckjonathan76 · 16/06/2017 11:30

Hi ladies, can I join? Due to start our first cycle of IVF at the beginning of July after TTC for 18 months and 6 failed IUIs. We are unexplained to but think age is playing a part (I am 41 next month and DH is 47). We have 2 kids each from previous relationships but none together. We've put off IVF for as long as possible but re-did my AMH last week and it has dropped from 8.9 last October to 4.6 (!) so we can't delay any further. My AFC was 10. I didn't know that the AFC predicts the number of eggs they expect to collect. Is that right? Also, lots of people seem to have transfers at 3 days rather than 5 days - anyone know why they transfer at 5 days instead of 3?
How does everyone feel going into IVF? I feel very apprehensive but starting to feel a tiny bit excited. Guess it's best to assume that it isn't going to work, especially first cycle. Hard to go into it thinking that.
Good luck all!


GirlcalledJames · 16/06/2017 11:41

What our clinic told us was that at 5 days it's easier to judge the quality, so if there is more than one candidate it makes sense to let them grow longer to see if quality differences emerge. If at three days it's clear which to transfer, or if the quality is low in gereral, they put them back then, because they will do better in the uterus.
Although they already knew for our first try that it would be a 5dt the day after the pickup. I don't know if that was because there were 5 of them?
My best friend got pregant first try with a 3 day transfer of a grade C so it doesn't mean it won't work.
My AF is several days late now so wondering when these injections will finally start!


Hopes2bmom · 16/06/2017 13:34

When it's a 5days transfer , the embryo is already a blastocyst which has a lot more chances of conception, so in my clinic if the response to the stims is not as expected which ended up with lesser eggs and poor fertilisation and also they consider the age factor to go for a 3dt, mostly they prefer 5dt


Hobbes39 · 17/06/2017 16:40

Hi! God I'm so behind on this thread - good to have new people join though! Welcome & best of luck to you all! Hope everyone is doing ok today?
LoPI - think I said before, but your numbers are a bit better but v similar to mine - my clinic didn't even entertain the idea of doing a short protocol for me, said they have better success rates for my stats with long protocol, and while I too 'underperformed' we did at least get reasonable numbers, if not great. It's so frustrating that they don't know why some people just don't respond as well... arg! I'm interested that you've been told cq10 might help, will have to ask my clinic about that if we have to go through a fresh cycle again.
GoodluckJ - to add to what others have said re transfer day - basically if you don't have many eggs (less than 5) you are much more likely to have a 2 or 3 day transfer as while tech is improving all the time, they still feel your body is probably the best 'incubator'. Also, i had 5 eggs fertilise last time and had a 3 day transfer as there were 2 obviously better than the others, so it was clear which ones to put back. However, if you have a few to choose from and they all look similar at day 3 then they will almost certainly take them on to day 5 as then the quality of them will be come clearer and also I believe a lot arrest between day 3 & 5 and the theory is if they survive to day 5 then your chances of success are higher.
how's everyone finding the down regging? I am drinking as much water as I can but still getting headaches all the time, and just as I thought hmm period was finished it seems to have started up again 🙄. I'm looking forward to a week on Tuesday when I should get some HRT!

OP posts:

79Karen · 17/06/2017 17:50

I've gone and got a cracking headache this afternoon, my fault really though as been into London shopping and didn't really thinking about drinking, even in this heat! Trying to flood the system now I'm home


Fox23 · 17/06/2017 20:09

Agree Karen, it really was very hot today. Same here, from London. And I had work today. From your experience, how often do you have to take time off during the process? And how long notice do I get? I'm abit worried as although I'm a manager, I have a boss too, and I don't want to tell him yet.


Hobbes39 · 17/06/2017 20:48

Hi Fox - in terms of time off I think it depends on where you are in relation to your clinic, but you don't really need to take time off until the week of egg collection unless you are unable to fit scans in before work and just be a little late in potentially? It's a very personal thing, but if you can I would advise taking the week off from egg collection to embryo transfer, but only if you can be busy, not sit at home doing nothing... you will get a good idea of when egg collection will be after your first scan when you have started stims - so you can then book a window of time off (if you have the holidays) so that you don't need to tell work about it at all. You will need the day of egg collection off at least as you are likely to be groggy and tender afterwards and I think the advise that. You won't know until the next morning how things are looking in terms of when embryo transfer might be - it could be Day 2,3 or 5, which is why if you can I'd book that week off to cover all bases. Hope that makes sense and helps a bit? X

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