Blood type and side effects of vaccine?

[RedToothBrush]

Just a quick straw poll as we've been having this discussion at home and wondered if there might be something in it.

What blood type are you?
Did you get a lot of side effects from the vaccine?
Which vaccine did you have?

but mine was pzifer,
my dh and dd had oxford with tiredness side effect

DD: B+, AZ
Basically rubbish, but probably only for < 48 hours.
Sore throat, cough, sneezing, feverish (?), headache, nausea, spent most (of first/one) day in bed

A+ ( known from pregnancy notes )
AZ 1st dose : slight fever and chills about 24 hours after , sore arm for about five days . Period came early .

positive/negative also has a difference... I have found a 'worst' blood type to have... according to this very biased data collection exercise.

Come on RTB, say what you were thinking & if the data proves it.

@yeOldeTrout

positive/negative also has a difference... I have found a 'worst' blood type to have... according to this very biased data collection exercise.

Come on RTB, say what you were thinking & if the data proves it.

I've had a bit of a mad day. I WILL do some counting up either tonight or tomorrow when I get chance.

I haven't forgotten!

I am wondering if the Os will fair best. My quick first count up on Friday seemed to suggest that, but will look properly at it.

I'm knackered and just need a quite evening tonight though I'm afraid.

So the early research seemed to suggest that if you were blood type O or Rh neg you had some kind of natural immunity to covid - you were less likely to catch it in the first place and you were less likely to get severe covid.

Conversely if you were blood group A or AB you were more likely to get severe covid

Whats interesting on this thread is that Pfizer recipients are definitely reporting less symptoms. I've heard that AZ is worse for the first jab but ok for the second but the reverse is true for Pfizer, so its possible that the Pfizer recipients just haven't had a second dose.

The other thing thats noticable is the sheer number of ABs on here. Myself included, and why I started the thread (its on my maternity notes).

If blood type O is giving a sight protective effect and blood type A puts you at slightly higher risk then thats interesting (remember if you are blood type A you can either be effectively AA or AO so may have some protection from a recessive O gene.) The AAs and the ABs may be the unlucky ones with their immune systems working in different ways which aren't great with covid but you'd perhaps notice it more amongst the ABs slightly because half the blood type A would be better off AOs.

Blood type B is fairly uncommon in the UK (8% of the population) but they are seem to be under represented on this thread.
Blood type O is the most common blood group (38% of the population). Its about a 50/50 split between those who had AZ who had not much more than a sore arm and those who had flu symptoms, sickness or more.
Blood type A is 32% of the population. More of the A+ group seemed to feel more ill than the O group.
But yes the AB group - particularly the AB+ is definitely overrepresented (AB is 3% of the population). Notably there were only 3 ABs who had Pfizer - the rest were all AZ. And the AB+ seemed to be split 1/3 mild symptoms to 2/3 who felt a lot more ropey.

Now this isn't good methodology by any means and its certainly not a big sample, but it does give me some food for thought. What is going on with the ABs??!

Thanks to everyone who contributed. I really would like to see more research on this being done properly.

BO positive
Pfizer, had sore arm for a couple of days after both doses
Ps. I have also noticed, lots of AB in this thread!!

A negative - AZ - flu like symptoms for 24 hours then tiredness for three day, arm a bit sore

Me, O neg no issues at all.
Hubby O pos no issues at all
Two of my brothers both O pos no issues at all. All AZ.
Equally none of my friends of differing groups had any issues

I’ve (A-) had Sinopharm and Pzifer; DH (O+) has had Sinopharm and Moderna. Neither had any side effects with Sinopharm. I had a sore arm I couldn’t put pressure on for a few days with Pfizer; he had no side effects with Moderna. DS1 (A+) had Sinopharm and was a bit grouchy for a few days. DS2 (O+) had Sinopharm with no symptoms. DN (O+) had Moderna and had headaches for a few days.

B+, two doses of Pfizer, sore arm both times, no other side effects

B+ - Pfizer first dose, no side effects.

A+ AZ.
Zero side effects bar sore arm for 3 days

OH. Same. & No sore arm

A- (mid 40s) AZ not even a sore arm!

I'm O positive.
1st Pfizer, nothing, not even sore arm.
Hubby O ( not sure + or -)
Sore arm, no other side effects.

I'm AB- AZ - I had minor chills and felt a bit sick for six hours. Slept well the following week.

DH O+ AZ - had flu symptoms the following day

DD B+ Pfizer - absolutely nothing

Oh, forgot to say, DD has had second Pfizer vaccine

A+ AZ vaccine, and I'm 57. Felt a bit rough for about 24 hours after the first one, nothing major. After the second my arm was sore for longer.

Amongst friends, I've noticed the older they are the less side effects from the vaccine. Which is maybe due to a failing immune system? (Friends are in their 70s and 80s).

Me: A+ Pfizer - sore arm after first dose and 24 hours of flu symptoms after second

DH: O+ - AZ first dose, Pfizer second (hope this doesn’t break your spreadsheet 🤣) - sore arm after AZ and flu like symptoms after second dose (same as me).

@RedToothBrush - there has been research with statistically different Type 2 diabetes risk, and there is a connection between covid and diabetes.

www.medicalnewstoday.com/articles/287309#Women-with-blood-type-B+-at-35%-higher-risk-of-type-2-diabetes
The researchers found that women who were blood group B positive (B+) were 35% more likely to develop type 2 diabetes than those with blood group O-. Women with blood group AB+ were at 26% higher risk of type 2 diabetes, those with blood group A- were at 22% higher risk and those with blood group A+ were at 17% increased risk.

The team says their findings for blood groups O-, B- and AB- were not statistically significant.

A-Pfizer... Mild effects overnight (hot flushes, headache, generally grotty after 2nd vaccine
DH A+... AZ absolutely fine

However, the most recent research suggests research showing differences are coincidence based on small sample sizes: jamanetwork.com/journals/jamanetworkopen/fullarticle/2778155.

Bit of a zombie thread but I'll contribute if you want some stats to represent the B group @RedToothBrush

Me: B negative, AZ, chills and slight headache. Recently had Covid too which was very very mild - just the headache, earache and tiredness for a few days.

Dh: O negative, AZ, no reaction at all.

DD1: B negative, Pfizer, a bit tired and spaced out for a few days.

I should add that DD1 hasn't had her second jab yet!