To think it will be revealed WLI cause physical aging

[Tuliptana]

Obviously the pictures of Kelly Osbourne are both sad and terrifying.

But a few women i know have also used this method for weight loss and their skin has lost elasticity. They look at least 10 years older. Is this side effect being under played?

Back during Covid lockdown I took the opportunity to focus on my weight, ate in a deficit, did my exercise, managed my carb intake, followed all the advice. Ended up with gallstones, a severe gallbladder infection, pancreatitis ,5 nights in hospital and an emergency surgery.

Weight loss is a trigger for gallstones, ironically so is weight gain.

It’s amazing how many people are concerned about our health isn’t it? People who didn’t care when we were morbidly obese. But now are terribly worried.

Any rapid weight loss can lead to gallstones. It’s irrelevant how you lose it. Nor is this an unexpected and new side effect.

Is this satire?

It’s a bit “My chain smoking ex-husband who works in the ski injury fracture clinic says he would never play golf as it’s too dangerous”.

Oh mate. Embarrassing!

Which is why maintenance dosing is available and exactly what I am doing. I work for the nhs and a lot of my colleagues who are at the very top of their clinical career are on wlis alongside me.

If she’s only a little bit overweight @GoneBackToTheWorld then she wouldn’t meet the prescribing criteria and so taking an anti-obesity medication when you’re not obese would be an odd choice. Never mind the apocryphal tales of all the patients piling the weight back on as soon as they stop. I do wonder why diabetics would stop taking a GLP1 if it’s controlling their blood sugars though. Seems a bit unusual to me.

If she’s “a little bit overweight” then she wouldn’t be prescribed them so I’m relieved to hear that, as a nurse, she’s not planning to go down the black market route.

And when is the medical establishment going to fund your professional research into the subject?

The speed of the loss is potentially an issue, if you loose slowly but steadily your skin can adjust to a certain extent.

If she's in a diabetes clinic, why are her patients coming off the jabs, they're prescribed for diabetes? My OH wont come off his, hes been on them for nearly 20 years.

In terms of weight loss whats her solution to losing weight then, her own and society at large (no pun intended). Just to stay fat in case you put the weight back on?

Being overweight makes you look older. Always.

We've decided that an investment in my health is worth every penny. I'm not in a clinical trial. I'm just on a normal private prescription with a supplier that supports long term tailored maintenance

Massive weight loss is ageing.
Being significantly underweight is ageing.
Being significantly overweight is ageing.

Who is that provider please if you don’t mind me asking?

I use oushk but there's lots of options of regulated pharmacies offering maintenance at monj.co.uk/mounjaro-maintenance-pharmacies/

Yep. Add age to any of the differentials and it’s maximising the effect.

Oh bore off.

It sounds like you know fuck all op. But it’s always fun to do a bit of speculative scare mongering mixed in with moral superiority isn’t it? I’m not sure you really know anyone who is on wli.

And there is no elephant in the room. Just another tedious load of crap from on op who hasn’t bothered to come back to their own thread for hours.

🥱

How are you defining longevity data?

Early GLP-1s started human trials in the 90s - 25 years of safer data is usually considered compelling.

Seriously, you extrapolate from people looking older because they have lost facial fat......to WLI making doing something bad to internal organs...(which dont have skin incidentally).

As well as losing facial fat, people on WLI will also lose visceral fat.

Visceral fat is the very worst most dangerous kind which coats internal organs. High visceral fat is an indicator of likely early death due to Type 2 diabetes, heart disease, stroke, high blood pressure, cancer, dementia, Alzheimer's and many others.

In reducing it, people on WLI are preserving their internal organs and increasing their life expectancy.

Not as much as visceral fat will.