To think it will be revealed WLI cause physical aging

[Tuliptana]

Obviously the pictures of Kelly Osbourne are both sad and terrifying.

But a few women i know have also used this method for weight loss and their skin has lost elasticity. They look at least 10 years older. Is this side effect being under played?

Since WLI have come along Ive never read so many opinions and apparent 'facts' about how losing weight will shorten your life, because of course fatties will nearly always lose weight the 'wrong' way, Cambridge diet, calorie counting, SW, WW, keto, low carb, low fat, we're just all wrong all round.

So now WLI are the new 'wrong' way to lose weight hastening our demise much much faster than a nice thick cloak of yellow fat around our internal organs ever will

Well I have been using WLI for about 10 months. Have lost about 2 stone and feel so much fitter ie not breathless walking up hills,joints not painful etc .
Yes my neck has aged ,but can deal with that over looking fat !

Well I lost 8 stone and have been told a huge amount of times how I haven’t just lost weight but about 20 years. My health is back to where it was 20 years ago in terms of blood pressure, cholesterol etc.. so I have no regrets and plan to stay on it.

Actually, there is more to it than that. I was listening to a plastic surgeon talking about the difference in the internal tissue of people on WLI. It's more "friable" I think he said. Other general surgeons he'd talked to had also encountered this when operating on internal organs. It has a markedly different texture and strength and is difficult to operate on.

Obese people get osteoporosis you know, my friend is one of them.

https://pmc.ncbi.nlm.nih.gov/articles/PMC5183727/

Women of a certain age who lose weight fast commonly suffer skin sagging.

Kelly O has been on injections the public can't get in the UK (Ozempic) and both she and Sharon have claimed that their ability to eat has been permanently/long term affected by it.

I know they've been through a lot this year but Kelly has to be either telling the truth about her inability to eat or is still on the injections because God love her she looks really ill.

She looks older than her Mum at 41.

It's really very sad.

I think it looks worse on her because she didn't have much to lose.

It's clearly gone too far, in her case.

Please leave these women alone. Stop attacking their appearance. Use one of the millions of other people on them. If you need someone famous try Serena Williams. Sharon is elderly, she’s previously suffered cancer, she’s grieving, Kelly has never once said ghe drugs rendered her unable to eat, she’s asking people to leave her alone, her father died and she’s struggling.

shame on you. Absolute shame of it.

I can't find a single reference to back this up.

You didn't look very far, this took me one search to find.

pmc.ncbi.nlm.nih.gov/articles/PMC10213739/

That's a letter to editor. I was looking for a peer reviewed paper. It appears to be about intestinal issues

Also being obese is a major risk in surgeries

I found it in one minute, I'll bet there's more. It's in the archive of the National Library of Medicine. It's a bit much to write it off as a "letter to the editor" as of it was the Daily Mail, when it contains two pages of detail, charts and graphs and ends with a warning to medics to look out for problems with the small intestine in humans on GLPs.

That is true but GLPs are not the only way of addressing that problem, it isn't an either/or issue.

Sure they said this.

I think it is your response to that poster that is the sort of reason the WLI are getting pushback though.

As I see it, they are an option, and for people who have very real health issues and plenty of reasons the weight loss is hard - and it CAN be complicated; I have good friends who have had weight battles and I am fully on their side that there wasn't an easy fix through traditional weight loss methods - I think they are a godsend.

However, not everybody's situation is the same, and for many people, especially with only a little to lose, diet and exercise can actually work and, as I see it, should be the first line of attack. It is the idea that that is now somehow outdated and ridiculous that I think people see as the dark side of the WLI.

I just think everyone should make their decisions based on their situation - and we can never really judge that from the outside.

It is the polarised positions - it is cheating, they are absolutely too dangerous regardless of the user's current obesity-related dangers vs they are essential and anyone who raises even the slightest misgiving is simply a jealous naysayer who has zero understanding of science - that are likely to lead to an unhealthy discussion around them.

The truth, as ever, is likely to sit somewhere in the middle: they can be useful in the right circumstances where clear benefit outweighs any misgivings.

But I don't think poo-pooing healthy diet and exercise is a reasonable standpoint.

Did you bother to read the link?

It has nothing to do with surgeons observations on operating on humans internal organs and everything to do with GLPs increasing intestinal length in rats and mice.

Something which has NOT been observed in humans.

It’s taken me 18 months to lose 29kgs on Mounjaro and if it had aged me (it hadn’t) I couldnt have cared less now that Im no longer on BP medication, pre diabetes medication and statins. My blood results are at the fantastic side of normal and I think it means my internal organs are working really well. Saggy skin, I’m 68, is a tiny price to pay for all of the health benefits that’s come with my weight loss.

Oh yes that simple. Ignore research, the studies on obesity, of the physiological and hormonal changes it causes.

Ignore the body changes obesity caused that makes weight loss almost impossible for so may people.

A MN has spoken and shared the never before shared knowledge that all you need to do is be in a calorie deficit .

Whodathunk?!

Coming up next she shares how alcoholics should just drink less, smokers should just not smoke and junkies should just not take drugs.

And for investors just but low, sell high and you will make money.

SIMPLE!

Currently in the states I am told you are advised to stop the medication a month before surgery is this the case ?

Nobody poopoos healthy diet and exercise.

You still need to do both on GLPs. But the WLI simply removes the physiological impacts that makes this nigh on impossible for most people with obesity.

My DM, T2 diabetic, obese for most of her life is now in the final stage of vascular dementia. Part of my motivation for getting my own diabetes under control and lose weight was to try to avoid dementia.

Dementia is hell, not just for the sufferer but also for their family. As it progresses, the person you love disappears. The person you are left with may be fearful, angry, vicious, violent. My DM has been through all of these. Now all we have left is a barely recogniseable person, doubly incontinent, mostly asleep. No quality of life. If my dog was like this I would have him pts but humans have to suffer on.

I am taking mounjaro and doing what I can to avoid my DCs having to watch me go the same way.

Where I am it’s one week as it supposedly keeps you safer during a general anaesthetic - seemingly your intestine isn’t so full and there’s less chance of swelling your own vomit. But I’m sure someone else can explain it better than I have.