To think it will be revealed WLI cause physical aging

[Tuliptana]

Obviously the pictures of Kelly Osbourne are both sad and terrifying.

But a few women i know have also used this method for weight loss and their skin has lost elasticity. They look at least 10 years older. Is this side effect being under played?

Where are all these people getting WLI?

Just to understand the question properly, what do you mean by physical aging?

Skin sagging or looking gaunt is common for any method of weight loss where a significant amount of weight is lost. It isn’t an indicator of other ‘aging’ happening within the body.

Effects on internal organs can be measured by blood tests etc so they would be well known about already.

They might still be learning about very long term effects but the Osbournes/most other celebs wouldn’t have been on it for long enough yet to get those anyway.

I have lost over 7 stones on WLI with still around 4-5 stones to go.

Without a doubt I look older than I did but that is because I have lost the weight which was puffing out my skin. I dont look old for my age, I am looking my age (59).

Internally I will have lost a lot of fat which will have surrounded my organs. This is a good thing.

it looks more like extreme buccal facial lipo not (just) ozempic. Super thin women, even those dealing with anorexia don't necessarily have skeletal faces until they're really seriously unwell. Think of Victoria Beckham, she's been teeny tiny but never looked quite like that although obviously everyone loses fat in different places.

VB also has a lot of facial filler though TBF

Oh what twaddle.

Looking older due to loose skin is not the same as 'physically aging'.

Looking older is a problem encountered by anyone losing too much weight, whatever method they use.

I have lost 29kg on WLI, but on low doses, slowly over a year and have been going to the gym 4 times a week and doing lots of weights/strength work.

I look much younger than my age, and don't have lots of loose skin. Indeed I am starting to look quite lean and a little defined, exactly how you would expect someone who works out regularly to look.

Using Boditrax machines my metabolic age is 15 years younger than my actual age

People with cash and access to less than reputable private prescribers have always been able to buy their drugs of choice.

A friend of mine lost 9 stone This was before the WLI. He didn't look much older after due to saggy skin etc

Im talking about who are buying it online and are lying about their BMI. This is a huge market but if not monitored by a qualified doctor, who knows what damage is being done.
They wont be getting regular blood tests .

I agree with PP, I think you're conflating cosmetic ageing with physiological ageing. There is overwhelming evidence that these drugs improve heart health, reduce cancer risk etc. It's the severe reduction of fat in the face that makes some users look older.

You also can't claim that that's the reason why Kelly O looks frail. She's still deep in grieving her dad's death and there's obviously a lot going on with her now. I think it's pretty bad taste to start a thread invoking her name for the basis of your argument.

Oh for god sake, let fat people lose weight at they see fit and stop being so judgey. It’s tiresome.

Many (majority) of people use WLIs as a tool alongside healthy habits - nutrition, weight training etc.

Of course, a minority abuse them.

Sorry but no if it starts a discussion and stops young women abusing weight loss medication that was never developed for them , then it might just save a few lives.

Its almost as if no one wamts to talk about the elephant in the room..

There is overwhelming evidence that these drugs improve heart health, reduce cancer risk etc.

It’s too soon for there to be overwhelming evidence of anything long term. I won’t be around to see it but I suspect it’ll be a health scandal in 30/40 years.

People who are lying about their BMI, not telling their GP they are on WLI only have themselves to blame.

I agree. DH aged terribly while on Mounjaro. Yes he lost the weight but he looked really ill. He stopped taking them and has put some weight back on but his face has still aged from what it was before

But then it is not the WLI themselves that are causing the physical signs of aging, it’s the abuse of WLI by people that don’t need them. Stopping the abuse of unnecessary medication is a different issue. I’m saying for the vast majority of people the benefits outweigh the risks (my GP certainly thinks so).

If people are taking extreme measures then that is a different issue, I’m not seeing this in real life (although you may be).

Totally agree. It will be like the silicone breast implants x 10 000. Mainly due to the ease of getting hold of it.

I’m not sure you can use the Osbornes as a good example as they’re practically made of plastic these days and so there’s not much natural left to look at regardless of WLI.

I do think sadly that WLI are going to be revealed as a medical scandal in 5/10 years time when the real longer term health effects become apparent.

As it is the impact on the pancreas and gall bladder is already known and I personally already know two people who ended up in hospital because of the jabs, and both of whom now need gall bladder removals and have pancreas damage.

But nobody who is doing well on the jabs wants to hear that, because if you’re desperate to lose weight, you’re given an out and you take it and do well on it, then it’s not a message you want to hear that you’re likely doing yourself other damage in the process.

It’s understandable, and nobody should be judged for wanting the jabs if they’re seriously obese.

But that doesn’t mean that the effects should be discarded.

It’s like any medication, it’s a fact of benefit vs risk, and IMO it’s only a matter of time before it becomes apparent that the risks outweigh the benefits in many instances and the criteria become more tightened.

But if he had lost the same amount of weight without monjauro it would have same effect surely

Obesity also causes accelerated / premature cellular aging. So what’s your point?

Save lives? You wot?

As the saying goes, at a certain age you can either have a nice face or a nice arse. Thin is more ageing to look at.

How would a GLP1 medication cause internal organs aging, I would love for you to discuss your reasoning behind this and how you think this is physiologically happening.

Of course the physical aging look makes sense as it would with any rapid weightloss - have you never seen any (sad) photos of people suffering from anorexia, a teenager can look like they are in their 40s.

Don't pretend this is some altruistic move on your part. You're using her current appearance to hammer her. Jesus, haven't we had enough of women tearing women apart over their looks by now? It was so obvious watching her at the BRITS that her frailty isn't about WLI. She's BROKEN by grief.

This. People on WLI who are under 35 look young and fresh… because they are.