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Share your dilemmas and get honest opinions from other Mumsnetters.

To wonder why they can’t make a Covid vaccine that actually fucking works?

218 replies

Capitane · 23/01/2023 17:45

Everyone I’ve known who’s had it/got it has been vaccinated and/or boosted.

There’s been two years in which to create a vaccine that actually works rather than just reduces symptoms, in some cases…

OP posts:
bronzepig · 23/01/2023 21:17

Florenz · 23/01/2023 21:15

There's no incentive for Big Pharma to create vaccines that work 100%, there's a lot more money in endless "new and improved" vaccines that slightly reduce the symptoms that they can sell to people/governments every year.

How do you square that with the fact there are vaccines that have 100% efficiacy?

Or the fact that in trials coronavirus vaccines showed almost 100% effectiveness?

Onnabugeisha · 23/01/2023 21:22

bronzepig · 23/01/2023 21:17

How do you square that with the fact there are vaccines that have 100% efficiacy?

Or the fact that in trials coronavirus vaccines showed almost 100% effectiveness?

There are no vaccines with 100% efficacy.
In the trials, the covid vaccine that showed the highest efficacy was the Pfizer one but they were measuring effectiveness to prevent death. Not hospitalisation. Not symptoms.

The goal of a vaccine isn’t to eliminate or reduce symptoms, but to reduce the severity of the disease enough so that you don’t de.

sst1234 · 23/01/2023 21:24

What would be the point? Big pharma already coined it in. Mission accomplished.

TheWildOrchid · 23/01/2023 21:25

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bronzepig · 23/01/2023 21:25

Onnabugeisha · 23/01/2023 21:22

There are no vaccines with 100% efficacy.
In the trials, the covid vaccine that showed the highest efficacy was the Pfizer one but they were measuring effectiveness to prevent death. Not hospitalisation. Not symptoms.

The goal of a vaccine isn’t to eliminate or reduce symptoms, but to reduce the severity of the disease enough so that you don’t de.

What do you mean?

Of course there are vaccines that have ~100% effectivness in preventing infection.

And here is the press statement from the sub study where 100% effectiveness in preventing infection was demonstrating regarding infection:

Vaccine was 100% effective in preventing COVID-19 cases in South Africa, where the B.1.351 lineage is prevalent

www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-confirm-high-efficacy-and-no-serious

As has been posted, these figures tend to wane in a real world setting, it doesn't mean they were lies though.

Onnabugeisha · 23/01/2023 21:26

sst1234 · 23/01/2023 21:24

What would be the point? Big pharma already coined it in. Mission accomplished.

Why shouldn’t they make a profit? Profit isn’t a bad thing. It’s only when people get greedy it becomes an issue. We are having strikes to get better pay for nurses and paramedics, why shouldn’t the research scientists and medicine manufacturers also make good money? They’re also saving lives. Millions of lives.

rockly · 23/01/2023 21:27

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As a working science I would say I'm not naive regarding trial data no...

As I said, these claims were not lies or untrue, they were based on the available evidence at the time.

More restraint and accurate reporting by politcians/governements etc would have been prudent however.

TheWildOrchid · 23/01/2023 21:28

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TheWildOrchid · 23/01/2023 21:30

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bronzepig · 23/01/2023 21:31

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I find it fascinating all these kinds of posts rage against Pfizer for some reason (ignoring J&J, moderna etc, despite the fact the vaccines developed by these companies show similar effectiveness, side effect profile etc).

Almost as if these claims are just being repeated from the large anti-vaccine disinformation groups who are weirdly focussed of Pfizer for reasons that I do not understand.

TheWildOrchid · 23/01/2023 21:36

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MysteryBelle · 23/01/2023 21:49

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As with all vaccines? Vaccines historically have always been meant to stop you getting it. That’s what a vaccine does. Not just lessen symptoms. The left recently changed the definition of the word vaccine. A significant number of people also have had terrible side effects from the Covid vaccines. My son’s pediatrician cautioned us that teen boys had a higher chance of getting an enlarged heart with the vaccine and so we decided not to let him get it. My husband was forced to get it for his job and he developed A-Fib right after, he’d always had a perfect heart and regular and low heart rate before. The nurse in charge of the other nurses at the ER said they’d seen ‘a lot’ of people coming in with vaccine induced afib and his cardiologist he had to go to told him it was the vaccine. My sister got it with no side effects that I know of. My brother got it and now gets rashes all the time. The point is, a significant number do have side effects as listed on the database that records them and it should be looked into.

The left also funded and concocted the virus. Fauci funded, with tax dollars, the man who developed the coronaviruses in the Wuhan lab, the very one which unleashed the covid 19 virus. This is fact, not my opinion, not a tin foil conspiracy theory. Look it up for yourselves and do your own research. Rand Paul in the USA Senate is just one of the people looking into this. I used to trust vaccines, now I don’t automatically trust the people making them anymore.

bronzepig · 23/01/2023 21:52

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You seem to be swerving the point that you only reference Pfizer, which indicates you're not thinking for yourself but simply copy pasting claims from those that are in the anti-vaccine industry.

Seasonal boosters for various vaccines is not a new concept.

As with all vaccines, a risk benefit analysis is conducted to establish which demographic groups it's worthwhile to offer them to. In the UK, a minority of people who are high risk are offered a booster.

chronictonic · 23/01/2023 21:53

haveyouopenedyourbowelstoday · 23/01/2023 18:11

I nursed throughout Covid. In the beginning people were literally coming in to die. It was horrific.
Now they aren't.
The difference?
A vaccination that clearly doesn't work?

And a mutated and less aggressive strain (Omicron)?

My understanding is that the better outcomes are due to a combination of the vaccine, Omicron & a better understanding of treatment options/approach & drug possibilities (antivirals etc)?

rockly · 23/01/2023 21:55

a significant number do have side effects as listed on the database that records them and it should be looked into.

This has similar vibes to the OP.

This is something that is continually being looked into, and is how specific side effects have been identified as causally associated with these vaccines.

TheWildOrchid · 23/01/2023 21:57

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TheWildOrchid · 23/01/2023 22:01

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VickyEadieofThigh · 23/01/2023 22:11

Greatly · 23/01/2023 18:51

I've had three jabs then got Covid and was pretty ill. I am not going to bother with the fourth jab unless there's some sort of new fatal strain.

I am an absolute martyr to my chest - every cold I had as an adult until the end of 2019 laid me out and I'd be barking like a feckin' weak-chested German Shepherd for weeks after.

I had 3 jabs and then finally got Covid last October, aged 63.

It was like the mildest cold I'd ever had and gone within a week.

That's my Covid anecdote.

Onnabugeisha · 23/01/2023 22:11

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The evidence has been published repetitively in terms of the death rate before and after vaccine. It’s millions of lives saved.

TheWildOrchid · 23/01/2023 22:16

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Hazelbrazil · 23/01/2023 22:20

Covid vaccines stop severe symptoms but don't seem effective at stopping transmission. Stopping severe symptoms was more useful for delta when more people were severely ill dying. Vaccine may still be useful for elderly so symptoms less severe.

Onnabugeisha · 23/01/2023 22:25

bronzepig · 23/01/2023 21:25

What do you mean?

Of course there are vaccines that have ~100% effectivness in preventing infection.

And here is the press statement from the sub study where 100% effectiveness in preventing infection was demonstrating regarding infection:

Vaccine was 100% effective in preventing COVID-19 cases in South Africa, where the B.1.351 lineage is prevalent

www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-confirm-high-efficacy-and-no-serious

As has been posted, these figures tend to wane in a real world setting, it doesn't mean they were lies though.

No one has said anyone is lying though.
It is fact that no vaccine has 100% efficacy. None.

Sorry, but you’ve completely misunderstood that press release. It’s not saying the vaccine was 100% effective against covid, but only against one particular strain of covid. In addition, the placebo group only 9 fall ill with Covid so there was very little of the virus going around anyway, which means much of the 100% in the teeny tiny sample size of 800 people could literally be due to lack of exposure:

”In South Africa, where the B.1.351 lineage is prevalent and 800 participants were enrolled, nine cases of COVID-19 were observed, all in the placebo group, indicating vaccine efficacy of 100% (95% CI, [53.5, 100.0]). In an exploratory analysis, the nine strains were sequenced and six of the nine were confirmed to be of the B.1.351 lineage. These data support previous results from immunogenicity studies demonstrating that BNT162b2 induced a robust neutralizing antibody response to the B1.351 variant, and although lower than to the wild-type strain, it does not appear to affect the high observed efficacy against this variant.”

This part of the press release has a more accurate figure:
“Results from this analysis of 46,307 trial participants build upon and confirm previously released data and demonstrate strong protection against COVID-19 through six months post-second dose. From the 927 confirmed symptomatic cases of COVID-19 in the trial, 850 cases of COVID-19 were in the placebo group and 77 cases were in the BNT162b2 group, corresponding to vaccine efficacy of 91.3% (95% confidence interval [CI, 89.0, 93.2]).”

But of course, vaccine efficiency is best measured after millions of doses and immunity over a time line of years, instead of 7 days to six months.

Onnabugeisha · 23/01/2023 22:25

Sorry autocorrect, efficacy not efficiency.

Onnabugeisha · 23/01/2023 22:27

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What you mean misinformation like you saying regular winter excess deaths are due to the covid vaccine being a complete failure? Because that’s misinformation, to pretend that vaccines = no excess deaths.

Hazelbrazil · 23/01/2023 22:33

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Economic problems in the supply chain from lockdowns are getting better. UK problems are due to Tory mismanagement including Brexit which led to reduced trade and Putin thinking west was weak enough that he could walk into Ukraine which had put up ou energy bills