I think its perfectly possible but it depends on your personality. I think the more you do the more you can do and juggling becomes second nature. Ive always juggled in my job. Now i juggle my family life as well. We used a nursery not a nanny. We have no other help.
We do have a rule that one of us is in our home city. Not easy on me as dh works a 2.5 hour commute away 3 days a week so im restricted on travel options 2 out of my 4 working days.
Our dc are 3 years apart which gives a bit more breathing room. I have a cleaner who helps with laundry. Dh does as much as me domestically. I have a team at work who i delegate to so i can be flexible. Sometimes if someone is working all day on a project they wont need your input until the evening. Its good to be flexible .
I do work PT but 4 days (always 5 days of hours which i dont get paid for!!) and often do long hours around family commitments. I figure flexibility has to work both ways so if i work from home and take an hour out for a school assembly or docs appt i will work the time elsewhere and work get a lot more out of me than i do from them.
My directorship got lost in the post and yes no doubt my career would have progressed faster if i hadnt had children. My promotion is taking me longer than i hoped but i keep at it because i have a longer term goal and that will take me into my children's adulthood. Id hate to be knocking around the house unless we were superwealthy and i could do what i liked!
I only have one school aged dc the other is still in preschool. I cant do all the after school activities that some dc do but he does 4 a week which is enough for 7yo. Ds2 age 4 has finally started one activity on a weekend. I think its enough but others see an endless round of activities as essential. Each to their own.
I find the school run a slog on the one morning a week i have to do it. Much more stressful than the orderly nursery/breakfast club drop off which is quivk and easy. Still ds likes that i go to school one day a week and i see his teacher if i need to.
Its also nice to be able to afford holidays or a nice car, meals out, clothes (not all at once in my case sadly!). Work facilitates this. Also being able to provide for the kid's future: tutors, university, music lessons, travel, experiences etc. I think thats worth it too. Some people are lucky enough to do that on one salary. Others are happy with much less.
I think do what suits you. We are all different and gain fulfillment in different ways.