I have a job where my commute varies massively. I also have a long term health condition and generally commute by car (which has both pluses and minuses but is more tiring than by train, but cheaper).
The difference to my health, the state of the house, my work life balance, between a commute that's under 45mins and over an hour is extraordinary.
I don't have a husband to have dinner ready for me when I get home, or to deal with the cleaning or whatever. If I did, and I could really genuinely work 9-5, and the train lines were reliable and I was likely to get a seat, then I think I could do that commute. But it would still really be a case of up, train, work, train, eat, shower, sleep, repeat. I wouldn't like to be around for that little of family life though.
TBH I'd probably take a big pay cut to get rid of my commute. I'm firmly of the belief that you need enough money not to constantly worry but that beyond that time tends to be more important. But I'm naturally frugal and so my perspective may well be different from yours.
I'd deffo think if there was anywhere you could move either to a) be able to walk to a station or b) walk to work from the mainline station and/or c) make the house prices such that you could do it for a year or two, pay the mortgage down like crazy and then afford to give it up for something local if you hated it.