I thought it was a very good piece right up to the point quoted by BiologyMatters. She seemed to pull her punches towards the end, failing to make the fairly crucial point that "transwomen" these days are largely cross-dressers rather than men with gender dysphoria. Perhaps the Guardian made her tone it down.
I was glad she mentioned the boy Madigan, though. I expect he will add it to his collection of examples of being "bullied".
Deborah Orr was sacked by the Guardian when they relaunched as a tabloid in January.
About the comments being switched off - I agree it's incredibly annoying but I can also understand why they do it. On any controversial subject, e.g. racism, Islamophobia, trans rights, rape etc. the Guardian mods would always have to work flat out deleting offensive comments (or in the case of trans rights, fairly sensible, reasonably-worded comments, but heigh ho). So I can see why they just decided to disable comments on those pieces. They don't have a moral obligation to let readers comment on articles - it's entirely up to them.