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Weight loss injections/treatments
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August 2026 starters (Thread 2!)

203 replies

chocolatecoveredpretzels · 30/09/2026 22:53

Hi everyone and thanks for the bestowed honour of starting the new thread, Puzzled!

It’s so lovely to have all of you along for the ride on here. Thanks for keeping me company! I love reading how things are going for you and being able to ask questions or share things.

Yesterday, I tried on a fleece top I bought last year. It fit me so snugly last year, I looked like a burst sausage in its casing. Now it’s actually loose. My rings are starting to feel a bit loose too- I wear my mum’s engagement and eternity rings and on the cold mornings, they’re starting to slip down my fingers.

I’m down 1.9kg this week and, although I’m still feeling hungry, it’s not an all-consuming hunger that leads to binging. I’ve actually needed to add more food as what I’ve eaten today and yesterday ended up being 1300 calories and 1100 calories. Given that my watch is still estimating approx 3000 calories burned on a typical day at school, I know I need at least 1600 to have enough oomph. Is anyone else finding the same?

I’ll link this thread in the old one so everyone can find their way here.

OP posts:
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BrokenMetabolism · 15/10/2026 22:48

Hi. Found my way to this website as I was feeling disappointed with my weight loss on Mounjaro and needed some support. Reading about lots of people with huge weight losses and very few people like me makes me wonder if I’m going to be one of the non responders?

Lost three pounds in the first week but we’d just come back from hols and my holiday weight always drops off quickly when we get home. Since then I’ve just been stuck around 11 stone. This has gone on for seven weeks.

I am eating less, about 1200 -1400 cals per day. Cake/chocolate/sugary stuff/white flour only one serving per week as a treat on weigh day, but I have to say I don’t enjoy it like I used to. No cravings for the first time in my life. Eating lovely healthy food. Medium-low carb. So why am I not losing weight?

My face has slimmed down. My belly has gone down by an inch. But the scales are not moving.

Decided to stay on 5mg for another month as my appetite is really quite suppressed and I have to make myself eat my dinner in the evenings. I do eat a good breakfast and lunch though.

I’m on it because I have prediabetes and my hba1c didn’t budge despite losing 10% of my body weight last year. Cholesterol went down beautifully, but not my hba1c.

I did try to lose the remaining stone to get down to bmi 23 but just couldn’t make it. Ran out of willpower. And the weight began creeping up again.

Can’t understand why my body is behaving differently from how it’s behaved when I’ve dieted in previous years.

Sorry for the essay. And really glad for all of you that are doing so well on Mounjaro 💐

MiaN · 16/10/2026 06:37

@PuzzledObserver I would be annoyed too. People often say you are looking great when they mean you are doing great compared to what you were. Now if you told me you are BMI 20 and getting the jabs to get skinny, like some celebrities do allegedly, I will get it. Comparing you to someone like this, considering all the effort that you have put and all the success you have achieved so far is just silly. You deserve to live in healthy weight body and feel good and any comments that you should settle for less area not helpful or medically sound.

However people, even skinny people have thier own battles going on an the comment is reflection on them, not you

MiaN · 16/10/2026 06:42

@BrokenMetabolism welcome, we are chatty and supportive crowd. I don't think you are non responder as you are describing the desired effects such reduced hunger. I am sorry you aren't seeing the progress yet. I don't hate any advice, sorry but maybe a session with dietitian could help. I know most day have few weeks off data/food diary is great.

MiaN · 16/10/2026 06:49

I am feeling absolutely drained from my period and will be taking it easy again today. One of the worse side effects I had with ozempic was I my periods were every two weeks and that started when I moved to 0.5. I have no reason yet to think this time will be the same but I can't help but panic little. I am glad I am taking it slow going up doses, it gives me better odds to handle potential situations.

Twice this year, the first time before the jabs I went abroad and both times I skipped period for a month. Its probably normal to have a heavy period after skipping a month and being 48 it can be sign of peri. I hope it's just coincidence me going to 4mg for first week.

Greatfull to be working from home today.

PuzzledObserver · 16/10/2026 09:04

@MiaN You speak such sense, thank you! I’ve got no insight on the effect of MJ on periods - they are a distant memory for me - but sending you a virtual hot water bottle anyway.

PuzzledObserver · 16/10/2026 09:15

@BrokenMetabolism Welcome. I’m not sure if I’ve got the full picture here….. you lost 10% of your body weight last year to get to around 11 stone, but it didn’t reduce your HbA1C….. started MJ to try to lose the final stone to get to BMI 23…. Which would put you just over 25 at the moment, right?

Thing is, type 2 diabetes (and prediabetes) responds to weight loss in the vast majority of people, but not everyone. There are two components to it, insulin resistance and reduced insulin production. Weight loss improves the first, but not the second.

For most people the insulin resistance comes first, as a result of fat being deposited inside the liver. It will be there for a decade or more before insulin production isn’t able to keep up, and blood glucose starts to rise. Only then do you get diagnosed with prediabetes or type 2. And the reduced insulin production follows later, when fat gets deposited inside the pancreas and clogs up the beta cells. Both aspects are potentially reversible, by removing fat from the liver and pancreas. In most cases, that is achieved by losing weight overall.

However, MJ was developed initially as a diabetes drug, so even if you don’t lose much weight on it, you may find your HbA1C improves. I’ve read it is particularly good at removing visceral fat, which is what is needed to put your prediabetes into remission.

How have you accessed it - privately or NHS? I imagine they will check your HbA1C after 3 months.

Belladog1 · 16/10/2026 09:35

I'm loving reading everyone posts. They give me clarity and makes me feel I'm not alone in this journey.

I'm still not having any appetite suppression and the weight loss is woeful. I am calorie counting and I am mostly in deficit, but the scales aren't showing much loss. This week I wanted to lose 2 stone for my holiday (yep, that was a joke) and instead I lost 1Ib 🤔However, it's one pound .... so yey. It's better than nowt.

I have amended my next dose, due mid November to 1mg, which seems scary. I'm on 0.5mg at the moment, and to double it blows my mind. But it says that I should get more (any would be nice) appetite suppression on it. I should have gone up tomorrow, but I chose not to, so as not to ruin my last holiday of the year.

I have to say that, now I am over a stone down, my clothes fit nicer. Nothing is loose or baggy, but things that stopped fitting as they were too tight, now fit lovely and as they should. It has opened up my wardrobe again. I ordered two new jumper dresses this week, and I was debating what size to buy. I have been an 18-20 for a long while, mainly because I have HH boobs!! So I bought them in an 18, and I did think one looked a little large. But it will be fine. I also treated myself to a new jacket, but I got it in a size 16, and you know .... it fits. Maybe slightly snug over the boob area, but it does up OK. It was a winter coat, so hopefully by the time I wear it, I might have lost another few pounds.

Weirdly this week, I had a period. I am 52, and my periods stopped at 49. When I started the weight loss journey, my progesterone increased which caused spotting for 2 days. But last weekend I got a proper period - which has baffled me. Maybe I'm not taking WLIs and instead my pen got mixed up with the Benjamin Button injection, and I am getting younger? 😅

BrokenMetabolism · 16/10/2026 10:13

@PuzzledObserver
Last summer my routine blood test showed an hba1c in the prediabetes range and a high cholesterol. I self referred to the Oviva diabetes prevention programme and over the next six months went from 12 stone to 10 1/2 stone. Cholesterol dropped to normal but my hba1c did not budge!

GP advised to lose more weight and get down to BMI 23, but I’m afraid that I just couldn’t manage it and my weight started drifting up again. So, I started on Mounjaro hoping that it would make it easier for me to eat healthily like I did last year. Buying it from ASDA online as it’s easier for me to pick up at my convenience rather than wait in for deliveries.

It has made it easier, and I am eating as I did when I was losing weight last year ….but I’m just not losing weight!

Thank you for your advice and interest. I also have read that Mounjaro may improve insulin sensitivity even without weight loss. Planning to ask GP to repeat Hba1c after three months on Mounjaro.

In the long term I’m hoping to get down to a healthy weight and come off Mounjaro. Thought about my lifestyle last night while I was posting on here and the two things that have slipped are sleep and stress management so I think I’ll focus on that for a bit.

Thanks again 💐

BrokenMetabolism · 16/10/2026 10:17

@MiaN
Thanks! Yes, food diaries are really helpful and I’m tracking my intake in an app.

PuzzledObserver · 16/10/2026 11:50

@BrokenMetabolism Ok, got you, thanks for the further info. With that, a couple more thoughts, plus a minor correction.

I said above that weight loss doesn’t improved reduced insulin production, but realise that is not accurate. It can do, because those clogged beta cells can recover when the fat that shouldn’t be there is removed. But that takes months to reach its full potential, whereas the improvement in insulin sensitivity will be seen within weeks.

In both cases, if the underlying cause is something other than ectopic fat deposits in the liver and pancreas, then losing weight doesn’t make much difference, if any at all.

The other factor is that blood glucose is a function of the amount of glucose you’re putting in to your system. Simply put, the fewer carbs you eat, the smaller your blood glucose spikes a faster eating. Over time, that means a lower average blood glucose and a lower HbA1C. Is reducing your carb intake something you think you could do? It would need to be something you felt you could sustain long term.

You mention that your face has slimmed down and belly reduced by an inch. So actually, you ARE losing fat. Hang on to that, irrespective of what the scale says.

And finally….. if you carry on eating in a way which used to produce weight loss and now no longer does, there may be something else going on - something hormonal, which potentially could be addressed. So at some point, it would be worth asking your GP about that. But my advice would be NOT to cut your calories any further, 1200-1400 is already pretty low.

Do you exercise, and if so, what sort? Strength training is vital to preserve muscle when losing weight, doubly so for people on GLP-1’s. Muscles are also a great glucose sink. The more muscle you have, the better you will cope with glucose challenges at meal times.

PuzzledObserver · 16/10/2026 11:56

@Belladog1 just to say that I learned from the fasting program I’m on that there are loads of women who thought they had gone through menopause, but once they addressed their insulin resistance, their periods returned. Cos what was actually happening was PCOS/PMOS, which is another manifestation of insulin resistance rather than menopause.

Unexpected pregnancy is a possibility…..

But also -that any bleeding after menopause should be investigated. Unless you are 100% certain that it is an ordinary period, may be worth mentioning to your GP to be on the safe side.

BrokenMetabolism · 16/10/2026 17:02

@PuzzledObserver
Thanks.

I tried Michael Mosley’s Fast low carb diabetes reversal diet but didn’t get on with it so I keep my carbs to around 100 per day now, with a bit extra as a weigh day treat.

I’m actually quite active and strong. A new to me thing in the diabetes prevention programme was to move after meals, so I now clean the kitchen/dance/do squats after my main meals!

Other than that I do housework and gardening, look after grandchildren, walk three days a week x 60 mins and do callenetics three days x 15 mins.

Hoping for a little smidge of weight loss on the scales tomorrow but will try to focus on non scale changes too!

Gonksmum · 16/10/2026 18:29

I've just had my second weigh-in at the pharmacy after 4 weeks on 5mg MJ.

Pleased because I lost 3kg which is an average of 1.65lbs per week and in the recommended range. It seems that my 1500 cals daily is doing what it says on the tin. All good and I'm carrying on with 5mg for my next pen.

Housemum · 16/10/2026 18:57

I’ve not been on the thread as life has just been busy, good to catch up and see we are all getting there x

weigh in day for me:
SW 12 st 12
CW 11st 12 (week 7, 1 stone down!)
GW 11st

just about to reorder, torn whether to go for 2 months of 5mg as it’s obviously working or whether I might need the 7.5mg if loss slows down, but it costs about another £50.

There are bundle offers for ordering 2 x 5mg or a 5 and a 7.5mg which is why I’m dithering

Anseranser · 16/10/2026 20:21

I dithered too, @Housemum , but went for 7.5mg in the end as I have no side effects and suppression isn't particularly strong. First jab at that dose will be Tuesday next week.

Annoyingly this week my jab site has been pink for several days, but thankfully not sore. I must have chosen a poor location! Hopefully back to no reaction next time.

chocolatecoveredpretzels · 16/10/2026 20:32

Lovely to see everyone’s updates. You are all so helpful and knowledgable and I’m learning so much from you all.

I’ve got two more doses of 5mg in my current pen, but my doctor sent through 7.5mg on prescription for the next one, which I picked up today. I have had a trickier week and a bit and my weight loss has slowed, plus suppression doesn’t feel as strong as the first month on 5mg (or maybe I’m used to it now?)

I don’t know whether to go another two weeks on 5mg or dose up with the current pen to maybe 6mg then switch to the 7.5 the week after? What do you think?

OP posts:
Belladog1 · 17/10/2026 12:46

I currently don't have appetite suppression, but i have noticed that the jabs are helping me with buying healthier choices.

I went to Lidl today. I've never been to one before, but a new store opened 20 mins drive away (I live very remotely, so everywhere is a long drive). I went and in my past life I wouldn't have been able to resist the bakery section. The bread, cakes and pastries looked delicious, but you know what I bought ..... a multigrain bread roll to have for my tea tonight. I swerved the pizza and cakes, and instead bought a tuna steak for dinner, salad and I treated myself to a small bar of dark chocolate with hazelnuts.

It's very strange. I noticed it previously in Tesco once. I normally get a delivery, but once I physically had to go in store, and I was nervous. But again, I was unintentionally really good and resisted the yummy stuff.

Housemum · 17/10/2026 14:32

I’m really torn on whether to go up a dose (5 to 7.5), part of me wonders if it’s better to try to cope and lose weight on 5 as it’ll make coming off it easier? Also, while I don’t think I’m getting side effects regularly, last night my stomach felt “off” (not quite full on nausea) and it was jab day. A week or so ago I had a random vomit, can’t remember if that was jab day or not

Gonksmum · 17/10/2026 17:45

My 9th weigh-in day today and, after a mammoth Saturday sleep of 15.5hrs(!) I have lost 3lbs - 11.5 lbs in total since 22nd August when I first weighed. I am very pleased but realise that some of this will be dehydration due to sleeping so long.

@Housemum I would stick to 5mg if you're still losing. It's a tricky one with your bundle offers, though, as your loss may slow towards the end of the second 5mg pen. I am on my second 5mg pen and have just had my 9th dose. I'd like to stay on this strength next time too but will see how I get on in the next 4 weeks.

It's difficult to anticipate how your body will react to it going forward, isn't it?

SW - 15.12.25
CW - 15.0.75

Housemum · 17/10/2026 20:27

I decided to go with 5, got a pen from MedExpress as a new customer so saved a bit there

RemakeRemodel · 18/10/2026 12:56

I'm midway through my second month on 5mg and have lost nothing in 2 weeks. Wishing I'd gone up to 7.5mg but you never know, maybe I'll get a little whoosh. 6.5kg total in 2.5 months.

BrokenMetabolism · 18/10/2026 14:18

Weigh day yesterday - one pound off!
Not as much as lots of people on here but I’m hoping it will be the start of a steady downward trend 📉

PuzzledObserver · 18/10/2026 17:43

Weigh-and-jab day for me, 1.2lb down this week for a total of 17lb since starting MJ, with 22.3lb to go.

Jabbed 4mg for the 3rd time. Hoping I don’t get the sulphur bursts like last week, bleurgh! We went out for lunch today which means our evening meal will be lighter, Hoping that will help with not feeling so overfull come bedtime.

As of tomorrow I’m going to start monitoring my fasting blood glucose. My plan is to test it twice a week, on Mondays and Fridays, keeping a consistent time lag from my jab on a Sunday, then track the moving average. It goes in the spreadsheet with the record of my weight and the dose I have taken. This should enable me to see whether my fasting BG changes as I lose weight, and when (if) I increase dose. I’ll be able to tell if losing weight is not making any difference, as that suggests there’s no particular he’s;th advantage in trying to get lower. And then when I start trying to reduce the dose, I’ll be able to see if my BG starts creeping up.

Anseranser · 19/10/2026 13:37

This week's discovery: really nice soup. I used to love the Yorkshire Provender pearl barley vegetable soup, but I've not been able to find it for years now. Tried their "rustic vegetable and tomato" for lunch today and it's so tasty. I recommend it if you're looking for an easy and satisfying meal.

Rustic Vegetable & Tomato Soup

Rustic Vegetable & Tomato Soup

Wholesomely hearty rustic vegetable broth generously combined with lentils and red quinoa, finished with fresh Yorkshire parsley.

https://www.yorkshireprovender.co.uk/soups/rustic-vegetable-tomato/

HappyNewt · 19/10/2026 15:58

A somewhat different question for the group...
Shapewear - I will be looking for some good shapeware - a body or perhaps the body with the slip (but I don't really get how those don't ride up!).

I will need it to go under a full skirt and white blouse which is ever so slightly transparent....so either white or nude. I expect to still have to wear a bra. I will be sitting for a fair amount of time that I will be wearing it. Maybe just a cami will work...

Does anyone have a go to brand/ones to avoid tip?

Thanks!

For regular group update info. I went up to 7.5 MJ for my third pen - first jab last week and I have to say that I have finally started to feel more like I did first time around on the jabs. More suppression. The first 2 pens did not feel as effective. I will see what the effect has been on weight later in the week.