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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

May 2026 Mounjaro starters - thread 2

604 replies

madeinthe80z · 20/06/2026 04:47

Can’t believe we are in a new thread! Keep It up everyone StarSmileStar

OP posts:
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13
Boreded · 20/08/2026 00:51

NettleTea · 19/08/2026 22:23

Im still going strong on 2.5. Im not quite sure how, but it does seem to be working pretty much as well as it ever did. I have my lymphodema massage tomorrow so will be interesting to see if she notices a difference as havent seen her for 2 months

I bet she does…let us know what she says

NettleTea · 20/08/2026 13:27

Boreded · 20/08/2026 00:51

I bet she does…let us know what she says

she was really impressed, she said the skin and flesh in my whole leg have changed completely, and she is able to see the vessels right down to the last bit of weird fat storage left in my toes. It is most noticable in the right foot and ankle, which were the worst affected, so hopefully todays treatment has helped soften up those areas and will help to get them moving and out. I dont have to see her again for about 9 weeks now, rather than every 4 weeks not really being enough.
I have the lymphodema clinic in two or 3 weeks time, so that will also be interesting as I will need to be remeasured for the specialist garments and there will be a quantative proof of any change.

Boreded · 20/08/2026 13:57

NettleTea · 20/08/2026 13:27

she was really impressed, she said the skin and flesh in my whole leg have changed completely, and she is able to see the vessels right down to the last bit of weird fat storage left in my toes. It is most noticable in the right foot and ankle, which were the worst affected, so hopefully todays treatment has helped soften up those areas and will help to get them moving and out. I dont have to see her again for about 9 weeks now, rather than every 4 weeks not really being enough.
I have the lymphodema clinic in two or 3 weeks time, so that will also be interesting as I will need to be remeasured for the specialist garments and there will be a quantative proof of any change.

Ah that sounds brilliant. Pleased you’re seeing such a big difference…keep it up

KittensAndCupcakes · 20/08/2026 16:31

Such great news! 😃

TeamsThemeTune · 20/08/2026 18:32

Lovely news @Boreded!

I have a 5mg pen waiting for my 15th shot tomorrow but I am going on holiday on Sunday for 10 days. After last week's reckless foray into the unknown, which I think was around 3mg, I emerged largely unscathed so I am planning on 40 clicks (which is 3.3mg) and then will miss the following week. Does that sound like a plan?

Boreded · 20/08/2026 19:04

TeamsThemeTune · 20/08/2026 18:32

Lovely news @Boreded!

I have a 5mg pen waiting for my 15th shot tomorrow but I am going on holiday on Sunday for 10 days. After last week's reckless foray into the unknown, which I think was around 3mg, I emerged largely unscathed so I am planning on 40 clicks (which is 3.3mg) and then will miss the following week. Does that sound like a plan?

Yeah. Don’t want to be jabbing on holiday, I mean you’ve stuck to the diet for 14 weeks already, I think it’s ok to have a little break on holiday isn’t it…besides your stomach will have shrunk so how much extra could you really eat?

I know I have to be very careful when I’m away, I’ll be going from a sedentary lifestyle to 15k steps a day in 95 degree heat. If I jab I think I will really struggle to get enough in me because I feel sick too much, I need to be able to eat some higher calorie stuff to give me the energy to keep going.

I think it’ll be interesting for all of us this summer. Looking forward to seeing how we all cope :)

mollio · 21/08/2026 00:52

TeamsThemeTune · 20/08/2026 18:32

Lovely news @Boreded!

I have a 5mg pen waiting for my 15th shot tomorrow but I am going on holiday on Sunday for 10 days. After last week's reckless foray into the unknown, which I think was around 3mg, I emerged largely unscathed so I am planning on 40 clicks (which is 3.3mg) and then will miss the following week. Does that sound like a plan?

Sounds pretty good ! One week off is totally fine - it didn’t have an effect on me ( well 1 lb holiday weight gain that hasn’t gone just yet , but that’s ok ). You need to be able to enjoy your holidays without feeling sick. You could do 45 clicks which is 3.75 . That’s a common be for people to do . I didn’t for a month before moving to 5mg and it worked well

mollio · 21/08/2026 00:53

NettleTea · 20/08/2026 13:27

she was really impressed, she said the skin and flesh in my whole leg have changed completely, and she is able to see the vessels right down to the last bit of weird fat storage left in my toes. It is most noticable in the right foot and ankle, which were the worst affected, so hopefully todays treatment has helped soften up those areas and will help to get them moving and out. I dont have to see her again for about 9 weeks now, rather than every 4 weeks not really being enough.
I have the lymphodema clinic in two or 3 weeks time, so that will also be interesting as I will need to be remeasured for the specialist garments and there will be a quantative proof of any change.

That’s absolutely fabulous . It’s a miracle drug to be honest xx

PuppyKeep · 21/08/2026 13:21

Another 2lbs off this week.

Also, since starting MJ my psoriasis has improved. It's not clear but it's significantly improved 👏

TeamsThemeTune · 21/08/2026 15:24

I should have jabbed this morning but forgot because I've been in and out of the house all day, and my offspring have decided today is the day they want to talk my ear off every time I come back home. Bugger off!

I did however, remember to weigh in this morning, and am another 2lbs down this week. Total loss of 11.45kg / 25lbs in 14 weeks. Haven't managed the 2 stone loss I was hoping for before my holiday, but it's pretty close.

Have to go out again later, so I think I'll jab in the car somewhere quiet. 🙄

TeamsThemeTune · 21/08/2026 18:18

Jabbed in a car park and lobbed the box in a bin - oh the glamour!

I did 40 clicks because a) I'm nervous about digestive effects, and b) I would like to be able to actually enjoy all the lovely Greek food. I'm particularly looking forward to my first pizza in 3 months. I hope I don't regret it.

KittensAndCupcakes · 21/08/2026 22:18

TeamsThemeTune · 21/08/2026 18:18

Jabbed in a car park and lobbed the box in a bin - oh the glamour!

I did 40 clicks because a) I'm nervous about digestive effects, and b) I would like to be able to actually enjoy all the lovely Greek food. I'm particularly looking forward to my first pizza in 3 months. I hope I don't regret it.

Teams, I wish I had been a fly on the wall of your car - you must have looked well dodgy! But well done for finding a solution and have a brilliant holiday! When are you off?

PS What did you do with your sharps?!?

PPS Amazing weight loss!

TeamsThemeTune · 21/08/2026 22:50

KittensAndCupcakes · 21/08/2026 22:18

Teams, I wish I had been a fly on the wall of your car - you must have looked well dodgy! But well done for finding a solution and have a brilliant holiday! When are you off?

PS What did you do with your sharps?!?

PPS Amazing weight loss!

Yeah, shooting up in a nearly deserted car park like a junkie isn't my usual MO!

Used needle came home with me heavily wrapped in tissues and went in my sharps bin hidden in the back of my wardrobe.

Off on holiday early Sunday morning. I've still got laundry to do (nobody in my family can understand the instructions "don't wear anything this week that you want to take away"), and I haven't even tried on any of my holiday clothes which have been in storage!

This isn't like me at all, I'm usually all over this sort of organisation, but this year I just can't be arsed and I'm winging it for some reason. I'm sure it will all be fiiine. 😬

NettleTea · 23/08/2026 09:57

first time having a gain - only 300gm so hardly the end of the world. I have been lax in my tracking. scary to see how close the 'lose weight' calories are to the 'gain wait' ones though - Im certainly not going for the sprint, and I am only on the low dose of 2.5mg though, so I just need to keep on top of things and keep hydrated.

MrsBuntyS · 23/08/2026 11:32

Hi ladies haven’t been here for ages hope everyone is well. Has anyone gone up to 7.5mg yet? I’m about to finish my second 5mg pen and I’m ok. Have had bad lower abdo pain the last few days but I think it’s ‘women’s problems’ rather than stomach issues as it’s very low down. I am still losing but I’ve noticed the appetite supression is going off on 5mg. I’m also worried that they won’t give me the 7.5mg the closer I get to goal but then I don’t know if actually need it?!?

mollio · 23/08/2026 22:59

MrsBuntyS · 23/08/2026 11:32

Hi ladies haven’t been here for ages hope everyone is well. Has anyone gone up to 7.5mg yet? I’m about to finish my second 5mg pen and I’m ok. Have had bad lower abdo pain the last few days but I think it’s ‘women’s problems’ rather than stomach issues as it’s very low down. I am still losing but I’ve noticed the appetite supression is going off on 5mg. I’m also worried that they won’t give me the 7.5mg the closer I get to goal but then I don’t know if actually need it?!?

I am still on 5mg too - my 2nd pen I think …I went up to 3.75 before increasing to 5. The suppression is still very strong , but I am able to eat at times … it’s weird as it comes and goes . I have only just gone down to my pre- holiday weight , so it’s a bit slower . I think I need to do better with my water etc .
people have started to comment now recently that I have lost weight. So that’s been interesting ! I have been very honest if asked , I don’t care if anyone knows . What I did notice on holiday was how I felt so much more self confident and happy in my skin . I don’t consider myself a vain person , but I do like to look the best I can , for my own self esteem . I really felt the best I have in many years . I have had a lot of self loathing I think, that I have pushed down with clothes shopping and frantic exercise …. It’s been a revelation

mollio · 23/08/2026 23:01

NettleTea · 23/08/2026 09:57

first time having a gain - only 300gm so hardly the end of the world. I have been lax in my tracking. scary to see how close the 'lose weight' calories are to the 'gain wait' ones though - Im certainly not going for the sprint, and I am only on the low dose of 2.5mg though, so I just need to keep on top of things and keep hydrated.

You’re doing very well on 2.5 , perhaps a small titration up to 3.75 would be no harm ? I noticed when I did that it I kicked the weight loss back into action but with v few symptoms . The biggest symptom increase was with 5mg . I will be sticking at this for the moment

PuppyKeep · 24/08/2026 12:58

scary to see how close the 'lose weight' calories are to the 'gain wait' ones

Yes, it's super scary. This is my situation too 😭How can it be so close??

7238SM · 24/08/2026 14:37

@MrsBuntyS I've moved to 7.5mg dose just last fri, although I have been using the 7.5mg pen for a few weeks now. I went up in increments from 3.75mg (I think 2-3 doses), 5mg (2 doses), 6.25mg and last week 7.5mg. I did have mild diarrhoea the next day but can't say if that was diet related or moving up a dose? Generally I've had constipation if anything. Suppression does feel slightly more than the 6.25mg so shall stay on this dose for a while.

KittensAndCupcakes · 24/08/2026 17:17

PuppyKeep · 24/08/2026 12:58

scary to see how close the 'lose weight' calories are to the 'gain wait' ones

Yes, it's super scary. This is my situation too 😭How can it be so close??

It is normal for our body weight to fluctuate! We don’t need to be scared. Just wait a bit and watch for trends - then we can make wise decisions about what to do next.

NettleTea · 26/08/2026 10:16

mollio · 23/08/2026 23:01

You’re doing very well on 2.5 , perhaps a small titration up to 3.75 would be no harm ? I noticed when I did that it I kicked the weight loss back into action but with v few symptoms . The biggest symptom increase was with 5mg . I will be sticking at this for the moment

I still have the reduced food noise - so what does the increase in medication do beyond the food noise. I know Im using it for the anti inflammatory effects for my lymphodema and was told to stay low, but I wasnt sure if there were other things going on. I dont want to end up more constipated if it reduces gut movement further, as only just about on top of it now!

NettleTea · 26/08/2026 10:17

although I see that the 2.5 is not considered a full medical dose

PuppyKeep · 27/08/2026 11:54

Split dosing is still working well. That's all I have to report atm.

Weigh day tomorrow 😬

mollio · 27/08/2026 16:31

NettleTea · 26/08/2026 10:16

I still have the reduced food noise - so what does the increase in medication do beyond the food noise. I know Im using it for the anti inflammatory effects for my lymphodema and was told to stay low, but I wasnt sure if there were other things going on. I dont want to end up more constipated if it reduces gut movement further, as only just about on top of it now!

yes I suppose if it’s not broken don’t fix it !!
I found my willpower weakened closer to day 5 and I nemeses to go up to get more suppression for longer . I think I need to be a bit stricter on my water at the moment though . I am plateaued on my pre- holiday weight ( which could be worse I know !)

Boreded · 28/08/2026 10:40

NettleTea · 26/08/2026 10:17

although I see that the 2.5 is not considered a full medical dose

I’m still doing the 2.5, the way I see it is that it is working so why go up.

I haven’t jabbed this week before the holiday, and honestly besides a small amount of hunger there really isn’t much difference, so I am glad that I stayed on the 2.5 so there wasn’t a drastic drop off.

My last jab didnt seem to be as effective either, it was like number 7 from the pen I think, so it was day 43. I didn’t get the usual side effects of a sore mouth or feeling sick for 2 days, and I had increased hunger.

One of my biggest worries was whether I would be able to eat the right stuff when I wasn’t jabbing, but honestly I’ve noticed no change other than a bit of hunger so looks like I’ve trained my body to stop looking for food (though truth be told I wasn’t a snacker I was a drinker/takeawayer).

Anyway…the official check in for today with my final pre-holiday weight is just under 220lbs which is a smidge over 50lbs down and meets my holiday stretch target (which felt too high for a long time) so here’s hoping I don’t do too much damage.