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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

kljdslhs877 · 28/06/2026 11:15

JT1987 · 27/06/2026 00:02

ive seen a few threads on Reddit people with pots and managing ok, do you mind me asking what your symptoms are? I also have low BP, episodes of passing out etc

Predominantly issues standing up, light headed standing up. There’s a link with hormones, anxiety and IBS. MJ can exasperate symptoms. I’ve done a couple of active stand tests and my data looks classic PoTS thus far (heart rate jumps and remains 30 bpm beyond the 2/5/10 mins). But I want to collect more data on days it’s cooler, I’m better hydrated and I’m at different points of my cycle before seeing a GP.

Lorrrrrre · 28/06/2026 14:43

SandwichesAndGingerBeer · 28/06/2026 11:11

Has anyone on here come to the end of their jabs now? I have my last dose next week, I’m not quite a goal, I wasn’t planning on getting more or moving to maintenance but I’m nervous about hunger returning and see Boots now have it available for £80.

Just wondering about experiences of coming off it.

£80? Is that for Mounjaro?

Lorrrrrre · 28/06/2026 14:44

kljdslhs877 · 28/06/2026 11:15

Predominantly issues standing up, light headed standing up. There’s a link with hormones, anxiety and IBS. MJ can exasperate symptoms. I’ve done a couple of active stand tests and my data looks classic PoTS thus far (heart rate jumps and remains 30 bpm beyond the 2/5/10 mins). But I want to collect more data on days it’s cooler, I’m better hydrated and I’m at different points of my cycle before seeing a GP.

I have read that it can help with IBS-D because mounjaro slows everything down 🙂

kljdslhs877 · 28/06/2026 14:56

Lorrrrrre · 28/06/2026 14:44

I have read that it can help with IBS-D because mounjaro slows everything down 🙂

Yes, I’ve been on it since January. It can do, but it’s a bit unpredictable, I can have weeks of no IBS symptoms and then an extreme not very nice day! I had a pretty tough time on holiday when my routine changed. I’m finding MJ exacerbates my anxiety a little which in itself causes issues with IBS. So that’s why I’m exploring PoTS to see how I can get myself regulated a little better, throw in possible early peri into the mix and it’s a quagmire 😫

But on the whole my experience has been positive and I’ve already chosen to stay on it, if they let me!

Lorrrrrre · 28/06/2026 15:55

kljdslhs877 · 28/06/2026 14:56

Yes, I’ve been on it since January. It can do, but it’s a bit unpredictable, I can have weeks of no IBS symptoms and then an extreme not very nice day! I had a pretty tough time on holiday when my routine changed. I’m finding MJ exacerbates my anxiety a little which in itself causes issues with IBS. So that’s why I’m exploring PoTS to see how I can get myself regulated a little better, throw in possible early peri into the mix and it’s a quagmire 😫

But on the whole my experience has been positive and I’ve already chosen to stay on it, if they let me!

I didn’t end up starting this week because I was in a flare up, it’s settling now so hoping I can start this week. I usually get flare ups a couple of times a month, so any easing of that would be welcome. Hopefully you can stay on x

AnotherPidgey · 29/06/2026 21:58

I've got my starter pack. I'm waiting for my DOMS to settle after running a half-marathon at the weekend, so I need the energy to recover in the next couple of days. I've got a niggle that needs to settle so resting from running for a few weeks ahead and the summer holiays are on the horizon, so that's a classic time for a pound or two to sneak on which then takes months to settle. So I'm really hoping that over the summer my appetite can be brought in line with what my body actually needs.

My general diet is good, I'm very active. I just struggle to cut back hard enough to undo a holiday here, a Christmas there, an occasional social event, and being short and middle-aged it's hard to eat less than half of what my lanky teenagers and 6ft husband need. Oh and plus a carby, hungry luteal phase for 10 days out of every 27🙄

I'd like to get back to a BMI around 23-24, and undo the gradual creep of the past 6 years since lockdown.

maybethisway · 02/07/2026 09:51

Hello everyone - hope you are all doing ok.

Weekly weigh in for me!

SW: 66.1kgs

Week 1: 63.7kgs (-2.4kgs)
Week 2: 62.3kgs (-1.4kgs)
Week 3: 60.7kgs (-1.6kgs)
Week 4: 60.0kgs (-0.7kgs)
Week 5: 58.8kgs (-1.2kgs)
Week 6: 58.1kgs (-0.7kgs)
Week 7: 57.4kgs (-0.7kgs)

Can't believe I've almost lost 9kgs. Seems nuts.

I don't know whether to stop after this pen (will be in a couple of weeks time) or order another one and titrate down.

Have anyone else reached GW and stopped yet? How is it going?

Beachforever · 02/07/2026 10:23

Well done @maybethisway! That is amazing.

I’m at GW and titrating down. I’m mainly titrating for all the other benefits. I really don’t want inflammation and insulin resistance to return. I’m going to try and find a dose where I don’t lose weight but still feel the benefits.

The highest dose I was at was 2mg for a couple of weeks. I’m now 1.5mg but I’ve lost a bit this week so going to go down to 1.25mg next week and stay at that level for a few weeks and see how I go.

OP posts:
maybethisway · 02/07/2026 10:30

I think I will do the same @Beachforever

I am hoping not to slip back into drinking as much as I used to - I have been totally disinterested whilst on MJ, it's been amazing. for the last few years I have really struggled to keep my alcohol consumption under control and I've certainly drank more than has been good for me.

I am loving being able to wear all my pre-children clothes again! There is still one pair of jeans that is a bit small but I think by the time I finish this pen they'll fit (either that or I'll throw in the towel and give them to a smaller person 😂)

Proteinpudding · 02/07/2026 11:48

Really impressive @maybethisway We're a similar starting weight though my loss is a lot slower than yours, but I know I haven't been the most disciplined just recently (I have stayed on a low dose so it's only going to work if I consciously put the effort in!)
Is the weight you are now the goal you had in mind? Just curious if it's what you expected. I have an idea but it's been so long since I've been lighter I don't really know what it'll look like at this age!

maybethisway · 02/07/2026 12:00

@Proteinpudding I am actually lighter that I had planned to be (my GW was 60kgs) but I think I underestimated how much muscle I used to have (I have none now!). I used to cycle a lot and did strength training a few times a week. I didn't look 'muscly' so I'd not really considered the difference in body composition but my body fat % was very low in hindsight. I'm 2.6kgs lower than GW and I'm obviously not quite as small as I was (unless those jeans have shrunk!!)

My goal as I'm coming off the WLIs is to get back to exercising consistently. That's a time issue for me with small kids (my weight didn't stop me exercising) - my 'all or nothing' brain finds it hard to cope with just doing the exercise I have time for (vs the extremes I am naturally drawn to 🙄).

I know I need my muscle mass as I get older though (I am 41) so I must work on that. Whilst my weight never stopped me exercising I do think I'll be more motivated now I am slimmer (and also not hitting the vino so hard, which is probably the key to everything for me).

How far are you from GW now?

ConnieClue · 02/07/2026 12:26

Just a little update from me: 16 days in (mounjaro 2.5mg) & 7lbs down!

No bad side effects & really enjoying the freedom my brain has from thinking about food constantly. I'm still eating a decent amount of calories...between 1300 & 1600 daily & am very happy with progress so far. 😊

Well done to everyone else too. All doing amazingly well.

Proteinpudding · 02/07/2026 12:51

@maybethisway I'm the reverse of you I think! I've strength trained consistently for a few years now, I'm hovering around 60kg and I'm not really sure what I'll look like at the lighter weights. I used to be quite happy around 55kg but I'm not sure if that would be right for me now, I do have more muscle in my arms and back than I used to. I definitely do want to lose another inch at least off my waist though, as that's really crept up in the last 2-3 years.
I do think I'll probably go a little lower than goal to have some wiggle room though, as I think managing without will be hard!

OnTheTop · 02/07/2026 15:32

I’m not really sure what I’m doing at the moment. I think I’m starting maintenance. Feel a bit like I’m flailing about 😂

I love my strength training so I know I’ve got a decent amount of muscle already. I’ve obviously still got jiggly bits but I’m very conscious of not wanting to lose more weight than is sustainable long term. Really don’t want to be caught up in the yo yo trap.

So I think I’ll try and stick here for a bit. It’s really helpful having this thread and reading about the other experiences.

Lorrrrrre · 02/07/2026 16:19

ConnieClue · 02/07/2026 12:26

Just a little update from me: 16 days in (mounjaro 2.5mg) & 7lbs down!

No bad side effects & really enjoying the freedom my brain has from thinking about food constantly. I'm still eating a decent amount of calories...between 1300 & 1600 daily & am very happy with progress so far. 😊

Well done to everyone else too. All doing amazingly well.

Edited

Are you following a specific diet?

ConnieClue · 02/07/2026 19:33

Not really! My normal diet but less of it, less snacking (have completely cut out morning snack) & less carbs, plus keeping on eye on protein. My meals were never unhealthy but my snacks were...

Partial to a bit of chocolate, lol.

Lorrrrrre · 02/07/2026 19:48

ConnieClue · 02/07/2026 19:33

Not really! My normal diet but less of it, less snacking (have completely cut out morning snack) & less carbs, plus keeping on eye on protein. My meals were never unhealthy but my snacks were...

Partial to a bit of chocolate, lol.

Amazing! Is it the appetite suppression that is helping you eat less? I’m taking my first jab tonight 😬

ConnieClue · 02/07/2026 20:11

Good luck! Exciting 😁

Yes, although not extreme suppression as I do still feel hungry. But definitely fuller for longer and no constant food noise, which was a problem for me, and feel much more in control of what & when I eat.

Proteinpudding · 02/07/2026 20:41

@Lorrrrrre similar to the PP, though I find it's not just appetite supression, because let's face it, my chocolate cravings often weren't hunger. It's that on WLI I don't have the same craving for dopamine, and I don't get a dopamine hit for chocolate like I used to. Same as for alcohol. It was most noticeable to me when I had fries in a local pub and I asked my DH to taste them because I couldn't taste the salt on them. They did have salt, but my brain wasn't reacting to the salt/fat combo and it was so noticeably missing that they tasted bland and disinteresting!

IDontKnowWhatYouMean · 02/07/2026 20:58

I'm pretty much at goal now (BMI is 23). I'm going on holiday this weekend and it's so good to feel happy about myself.

I'm just about to start a new pen, which will last me for a minimum of 4 weeks from Saturday (depending on whether I adapt the dose or not), then it will be decision time .....

I'm on Wegovy and have found the whole experience very positive - no side effects, just enough appetite suppression to stop the over-indulging, still able to enjoy food and drink - I'm reluctant to stop for all those reasons. It would be a no-brainer if it wasn't for the cost!

AnotherPidgey · 02/07/2026 21:38

I've done my first dose (Wegovy) tonight. I'm hoping I don't get digestive effects as that would be highly inconvenient at work!

I'm in the throes of my luteal phase when my energy is lowest and craving for quick fixes is highest. It will be interesting to see if the edge comes off that in the next few days...

At least my flabby mum tum is perfectly insensitive to put the needle in. I didn't actually notice it! (It always felt quite numb after the over-stretched pregnancy/ CS combination)

Lorrrrrre · 02/07/2026 22:58

Ahh just did my first jab in my thigh. Literally felt nothing, the needle is so fine, I am quite worried nothing has gone in?! 😂

It is definitely not as bad as the gestational diabetic tests in pregnancy!

kljdslhs877 · 02/07/2026 23:00

Lorrrrrre · 02/07/2026 22:58

Ahh just did my first jab in my thigh. Literally felt nothing, the needle is so fine, I am quite worried nothing has gone in?! 😂

It is definitely not as bad as the gestational diabetic tests in pregnancy!

I jabbed in my thigh when I went up a dose, I weirdly did find the SE less but maybe a coincidence. I bruised though!

kljdslhs877 · 02/07/2026 23:02

@AnotherPidgey I generally found my SE (when I had them) came 48 hours later, so hopefully you’ll be ok with work (assuming Wegovy is similar to MJ)

AnotherPidgey · 02/07/2026 23:09

kljdslhs877 · 02/07/2026 23:02

@AnotherPidgey I generally found my SE (when I had them) came 48 hours later, so hopefully you’ll be ok with work (assuming Wegovy is similar to MJ)

It did seem worth leaving it to the tail end of the week for that.

Plus while recovering from racing at the weekend, I have no important runs planned, but my general energy is back up from earlier in the week.