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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro - 10 Stone or more to lose - Thread 14

223 replies

TheBroonOneAndTheWhiteOne · 08/05/2026 21:10

Wow. Thirteen threads behind us and many friendships forged.........

We've even been turned into a Group Thread.
Grin

All are very welcome.

OP posts:
Thread gallery
5
52soon · 14/05/2026 19:26

@Springflowers2 I have only ever lost 1lb a week, it takes me 12-14 weeks to lose a stone and I used to compare myself with all the big losers but after being on it a year I’m very happy with my 1lb a week and it all adds up eventually the difference in my photos are incredible, you have done amazing take a look back through your photos to remind yourself of how far you’ve come.

Springflowers2 · 14/05/2026 20:23

52soon · 14/05/2026 19:26

@Springflowers2 I have only ever lost 1lb a week, it takes me 12-14 weeks to lose a stone and I used to compare myself with all the big losers but after being on it a year I’m very happy with my 1lb a week and it all adds up eventually the difference in my photos are incredible, you have done amazing take a look back through your photos to remind yourself of how far you’ve come.

Thankyou.xx

Doggymummar · 14/05/2026 20:30

Springflowers2 · 14/05/2026 17:38

What is everyone else doing..who is loosing weight very slowly..are you all just sucking up the cost and staying on 15 mg pens s ??
And can we have a conversation about what people are planning to do when they get near the finish line ..are you all planning to just stay on it for forever?
I should really of thought about this before now

Sinc3 I lost my job I can't afford mj anymore so switched to wegovy. I gained ten pounds last month as they have me start on1.7 and it did nothing. Started 3.4 or whatever on Monday and I am back to suppression again so hopefully will work. I've less than a stone to get BMI 25 but hav3 stayed th3 same for about a year now, not laterally just lis3 5 gain 6 lis3 7 etc

MCR24 · 14/05/2026 20:34

@Springflowers2 I'm now half a stone from my end goal. Since 1st January I've lost 1 stone 6 lb.

I'm expecting it's going to take quite a while to lose this last half a stone because I can't eat any less than I am now, so it's harder to be in a calorie deficit.

I'm carrying on with 15mg until I'm at goal and then I'm going to try and go back down to lower doses until I get the combination of sensible eating and maintaining the weight. I am expecting to need it in the long term. I read you should be on it for maintenance for the same time you were losing weight, I don't know how true that is.

TheBroonOneAndTheWhiteOne · 14/05/2026 23:59

Springflowers2 · 14/05/2026 17:18

I'm not sure ..but it's a stone since January and every now and again I drop a pound

As you're still losing, I'd carry on with the 15mg.

I know your rate of loss seems slow but it's the same rate most of us are at, by this stage.

I've been losing 2lb a month for ages. I'm perfectly happy with that.

OP posts:
TheBroonOneAndTheWhiteOne · 15/05/2026 00:10

I've only got to lose another 1lb to get to 10st off.
That's always been my goal.
I'm nearly there.

I'm a size 8 - 10 now, even though my BMI is very slightly in the overweight range. It's madness.

Anyway. Give me a couple of weeks and I should be there.

My next plan will be to titrate down the doses until I'm back on 2.5mg, where I hope to maintain. I'm going to buy 15mg pens and microdose from them.

OP posts:
tescovaluebread · 15/05/2026 07:18

Hope all is well!!

SW 144kg
CW 84kg
GW 75kg

Cant believe I have less than 10kg to go until I am at goal.

I remember specifically being 80kg at the age of 11. And actually I feel quite sad for myself and kinda get why I felt so huge and out of place because I was an adult weight??? This whole journey is actually quite emotional.

Anyway some NSV

  • dressing up more even when around the house. I Wfh, but I was wearing my jeans, belt and necklace yesterday rather than my joggers.
  • I can't hear my thighs rubbing together as I walk now! And I walk so fast 😅
  • I'm quite vain and keep looking at myself in mirrors and myself on teams. And just randomly start posing 😂

Any help on a shopping addiction I have developed 😭 for those who are at goal did your body size change much for the last 10kg? Because I keep buying clothes out of excitement and conscience that in 10kg time they might not fit 👀

Springflowers2 · 15/05/2026 08:16

MCR24 · 14/05/2026 20:34

@Springflowers2 I'm now half a stone from my end goal. Since 1st January I've lost 1 stone 6 lb.

I'm expecting it's going to take quite a while to lose this last half a stone because I can't eat any less than I am now, so it's harder to be in a calorie deficit.

I'm carrying on with 15mg until I'm at goal and then I'm going to try and go back down to lower doses until I get the combination of sensible eating and maintaining the weight. I am expecting to need it in the long term. I read you should be on it for maintenance for the same time you were losing weight, I don't know how true that is.

Ok ..that's probably what I need to do as well.

Springflowers2 · 15/05/2026 08:27

So one of the things I asked chat gtp was if someone comes of monjroro,but eats exactly the same calories as when on monjroro,will they put on weight.
And chat gtp said yes they would because the body won't burn sugar it will convert it to fat and store it with out monjroro stoking the fire in the background.
Some of the times I'm asking questions,I rephrase it in different ways and I get completely different answers ..so I'm not convinced it's to be relied on .
It talked about people being in starvation mode but not loosing weight ..yet I didn't think that was a thing ,as otherwise how would people be anorexic .
It kept telling me to talk to my provider of monjroro..but they are a business and want to make money,so won't want anyone coming of it .
I keep seeing in the media...reports of people piling the weight back on when they come of monjroro,then going back on it ,and it becomes a merry go round similar to people joining and leaving slimming world.
Then I read articles saying we need this drug for life , because it's like blood pressure meds or diabetes meds ...but who is pushing the theory we need this drug for life ..is it fact ???? Or is it drug companies pushing it.
I feel I can't get any straight answers

SilenceInside · 15/05/2026 08:51

@Springflowers2 AIs like ChatGPT are definitely not something that is fully reliable. They can include invented information, wrong information, information that's not in the sources that they reference. As you've experienced, how you ask a question makes a difference, along with how you respond to the each of its responses. The thing to remember is that contrary to the name, there is no actual intelligence to AI, not in the sense that we usually use it to mean. It is just a computer program which produces output according to its current set up. It's attempting to "learn" by improving the output based on the responses that it gets.

An AI should also be telling you to speak to your medical provider alongside any information or advice it comes up with.

The thing about Mounjaro, Wegovy etc is that they were invented and designed to help people lose weight not maintain weight loss. So the goal is to produce 5% of starting weight or more weight loss. Mounjaro is excellent at that! But, there really won't have been much consideration as to what people do once they've lost the weight. That wasn't part of the clinical trials done to get it approved.

Now that people have been using them for a while, people are now starting to think about what maintenance is and how that might work. There's no one answer, which is why it can seem confusing and contradictory. I think that each one of us will decide on what we would like to try which might be very different, depending on lots of different things. Someone who has never been morbidly obese, or who hasn't been obese for their whole life might make different choices to someone like me who has never been a healthy weight and had been morbidly obese for a long time. I definitely need to use Mounjaro as necessary to keep my weight stable for a decent amount of time before I try to manage without medication. Once I am at goal, I will move down doses slowly and see how I adjust. Hopefully at some point I will be able to stop altogether but I am not in a rush to do that.

Springflowers2 · 15/05/2026 09:22

@SilenceInside I did not know ,there was no studies done on coming of it or maintenance,that explains a lot ,and why I keep getting conflicting advice..
But if the NHS is now prescribing this ,don't they need to know what happens long term..or are they just planning on keeping people on it for life

FattyBumBumNoMore · 15/05/2026 10:29

I haven’t posted in ages but always read - keep going losers!

I’m now a smidge over 6 stone down, a whole Emperor Penguin as of this morning. I’m also on the cusp of falling into the merely overweight category. My target is still another 3 stone to lose though (literally feels like a stone on my tummy and one on each thigh). Dare I think now about how I’m edging towards maintaining?

So, my questions are…. If you’ve done 18 months on 2.5mg like me, how on earth do I titrate down when I’m ready? Even when you’re in healthy BMI will they still prescribe as I’m aiming for the mid point? I’ve just done 3 months with Fylde and they’ve been amazing, but I’ve noticed they’re not on the monj site anymore. What does that mean and should I be worried? They’re still claiming to be registered.

im hoping some of you long term losers might have some insight.

Rahgh · 15/05/2026 10:29

Hello I’m a long term lurker. Sorry as I feel that I’ve not really contributed and am now after advice and support. You were all very helpful when I started last August.
I’ve lost 3.5 stone but it’s been painfully slow since January. I was at 7.5 but I’ve come down to 5 as I am getting diorrhoea and gurgly tummy (still on 5mg 😫). I am definitely finding the suppression not as easy since January.
My MH has been a bit bleurgh (not weight related) and whilst I’m so happy to have lost the weight I have but I want to lose so much more and get solidly and consistently in the 16st bracket. I did start sertraline and counselling in December and have now been diagnosed with ADHD. I went a bit loopy on December and wondered if it was the mounjaro causing it but was happy to take the hit as sertraline and counselling means I am in a much better place. But I’m now wondering if the sertraline is causing the stall in weight loss.
I keep thinking “this week I’ll be good, more exercise, no snacks, prioritise protein and water” but then don’t really.
I guess I just want to vent as I’m frustrated with myself and fed up with gurgly belly and not being able to trust a fart!

TheBroonOneAndTheWhiteOne · 15/05/2026 10:36

Springflowers2 · 15/05/2026 09:22

@SilenceInside I did not know ,there was no studies done on coming of it or maintenance,that explains a lot ,and why I keep getting conflicting advice..
But if the NHS is now prescribing this ,don't they need to know what happens long term..or are they just planning on keeping people on it for life

I am quite sure that most people who need MJ are going to need it for life.

I'll certainly try to live without it, but I believe that I'll have trouble. So my plan is to:

  • reach goal
  • start going back down the doses
  • keep a close eye on the scales
  • see what actually happens if I do come off it
  • have no problem starting again and hopefully just needing 2.5mg

The NHS is always years behind in research. ChatGPT doesn't understand this.

I also think you should stop asking ChatGPT for medical advice @Springflowers2 There are too many variables for it to be reliable.

♥️♥️

OP posts:
MoneyJo · 15/05/2026 10:48

@FattyBumBumNoMore I'm nowhere near maintenance but you could titrate down by going for 1.25 from a 2.5 pen.

@Springflowers2 I am sure people are researching that side of things but it takes time and the main concern was getting weight off.

FattyBumBumNoMore · 15/05/2026 11:03

MoneyJo · 15/05/2026 10:48

@FattyBumBumNoMore I'm nowhere near maintenance but you could titrate down by going for 1.25 from a 2.5 pen.

@Springflowers2 I am sure people are researching that side of things but it takes time and the main concern was getting weight off.

That’s very true actually. Need to think outside the box!

Newnammmme · 15/05/2026 11:18

Morning everyone.
dropping in to keep updated.

start weight 315lb jan 25
current w. 206lb
using 15mg

next mini target 199 !

im starting to think of targets … I actually can’t believe it.

SilenceInside · 15/05/2026 11:26

@Springflowers2 the NHS are prescribing for weight loss at the moment to people with several serious health conditions. I would hope it would be an individual decision based on how those conditions are improving rather than a hard and fast general criteria. But, given it's the NHS, they might just do a hard cut off after some number of months based on no evidence at all, but just cost!

@FattyBumBumNoMore Fylde seem ok to me from their website, they are GPhC registered and passed their last inspection in May 2025. Whether or not they appear on Monj is down to the people who run Monj and might be related to business decisions by them rather than anything sinister. You can contact Monj and say that Fylde is missing and ask for it to be added back.

For maintenance, there are lots of pharmacies that will continue to prescribe. I don't know what Fylde's policy is but you could ask them. I agree that if you wanted to titrate down from 2.5mg you could just do partial doses and see how you get on.

@Rahgh sorry you're having a rough time of it at the moment. Constant diarrhea is clearly not what you want. Hopefully moving down a dose will help to resolve it. I don't know much about sertraline, hopefully someone else here can advise. Putting on weight is a side effect of sertraline according to the NHS website.

@Newnammmme great progress and fab to be heading towards new targets, you're closing in on onederland!

TragicMuse · 15/05/2026 11:49

Morning!

I’m feeling as though 12.5 is less effective than 10 ever was. I could eat the world today…

On a 7-day regime I’d be injecting on Sunday but I’m going to pull it forward to tonight. I’m just starving and not suppressed at all.

I’m planning to get to my target and titrate to a maintenance dose that suits me. I have T2D so I think I’ll always need it for that anyway. And I do not want to have worked and spent hard and then fuck it all with a regain.

But I need to get there first and it’s proving a challenge at the moment.

mounjaroatlast · 15/05/2026 14:05

Hi, thanks for the replies. To answer a couple of questions, the 3kg loss is over 3 almost 4 weeks.

The nurse told me to go up to the 5kg after 3 weeks at 2.5 because the suppression had stopped and the snacking was coming back and I wasn't feeling any effects at all. All of that has gone away now on the 5mg.

I have just ordered some dioralyte to make up some minerals, as my last blood test showed that I was low on potassium (3.5) and that was before starting MJ. I am drinking plenty as well, and am on other medication for the T2D that helps to protect the kidneys.

The symptoms have eased off a bit, I just managed a tiny bowl of soup and 1 piece of wholemeal bread.

Fingers crossed that I don't get the same again on the 2nd dose.

SilenceInside · 15/05/2026 14:13

Bit surprised that the nurse would recommend skipping ahead to 5mg without completing the 4 weeks on 2.5mg. The medication builds in your system each week, so another week at 2.5mg would still have overall increased the amount of medication in your system.

Anyway, it’s done and can’t be changed now. Glad you’re feeling a bit better, hopefully that will continue.

newtothegreen · 15/05/2026 16:18

TragicMuse · 15/05/2026 11:49

Morning!

I’m feeling as though 12.5 is less effective than 10 ever was. I could eat the world today…

On a 7-day regime I’d be injecting on Sunday but I’m going to pull it forward to tonight. I’m just starving and not suppressed at all.

I’m planning to get to my target and titrate to a maintenance dose that suits me. I have T2D so I think I’ll always need it for that anyway. And I do not want to have worked and spent hard and then fuck it all with a regain.

But I need to get there first and it’s proving a challenge at the moment.

I have just moved up to 12.5 and feel a little the same as you do. My suppression seems much lower now than it did on lower doses, which is strange but I wonder whether just par for the course in terms of taking a medication for a long-ish period of time. I can certainly physically eat more than I was able to at the start of my journey and also feel like I want more.
However, I am going to take your advice and move to a different regime in terms of frequency of jab to see if 10 every 5 days is a winner!
As another lovely poster has recently said, the amazing thing on this thread is that we may all have started with what on the surface looks to be the same issue, but the difference in each journey is truly staggering!

OvertiredandConfused · 16/05/2026 00:11

Hello lovely people, I’m back!

I’ve officially been approved to restart Mounjaro and I’m just waiting for my prescription to be delivered. The doc was utterly wonderful and has prescribed 5mg to start but suggested I just do a half dose to start with and see how I get on.

For those that don’t remember me, I had my gallbladder removed a few weeks ago and had to stop taking Mounjaro four weeks before surgery so I went cold turkey which was pretty tough.

This last week has been the hardest. I am now recovered from my surgery and can eat normally so sticking even within maintenance calories has been a struggling. I can’t wait to get back to normal now.

Looking forward to checking in here much more frequently again. I’ll do a proper weigh in when I know exactly what day I’ll be starting. In the meantime, I’m giving myself permission not to stress about what I eat over the next couple of days. I’m really not going to do any long-term damage between now and whenever the pen arrives!

Missingducks · 16/05/2026 07:35

Welcome back @OvertiredandConfused hope you're not too sore and the tooth fairy gave you something for your gall bladder (if you put it under your pillow for her).

RenegadeKeeblerElf · 16/05/2026 08:10

Morning all! Weigh in day and I'm tantilisingly close to being under 200lbs - fingers crossed I'll get there next week! I have been at this sort of weight before, but only briefly the last time I lost significant weight, and I didn't manage to maintain it for long, so it still feels exciting and new, even though I've still got a fair way to go.

SW 139.7kg

W1 -3.8 2.5mg
W2 -1.9
W3 -1.7
W4 -0.9
W5 -1.5
W6 no change
W7 -2.3
W8 -1.2
W9 -1.3
W10 -0.3
W11 -2.0
W12 -0.6
W13 +0.7
W14 -1.1
W15 -1.6 increase to 3.75mg
W16 -1.5
W17 -1.0
W18 -0.9
W19 -1.0
W20 -0.4
W21 -0.2
W22 -2.1
W23 +0.1
W24 +0.7 (Xmas)
W25 -1.9 increase to 5mg
W26 -0.7
W27 -1.8
W28 -1.3
W29 -2.3
W30 -0.6
W31 -1.3
W32 +1.1 (holiday)
W33 -3.2
W34 -1.0
W35 -0.4
W36 -1.2
W37 -0.7
W38 -0.4
W39 -1.6
W40 -1.0
W41 -1.1
W42 +0.7
W43 -2.3
W44 -1.4

CW 91.4kg, 48.3kg lost in 44 weeks