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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Has anyone NOT regained weight after stopping WLI?

149 replies

gettingalife · 25/01/2026 08:18

I’ve just read the responses to another thread about what happens when you stop WLI. The majority or people say they’ve regained all weight lost. This is so depressing.

I’m at my target weight now, after losing 3 stone on 5mg, and am terrified of regaining when I stop. I’ve injected 2.5mg for the last 2 weeks and already feel my appetite increasing. I’m tracking calories (1500 - I’m 5ft 1), run 5k 3x a week and walk at least 10,000 steps a day so I’m doing what I should (I think?). Anyone not regained? And what have you done?

OP posts:
FlyHighLikeABird · 28/01/2026 11:31

climbintheback · 27/01/2026 19:18

I know I may be missing something but if you know what you are eating when you get to goal why not carry on the same diet when you have stopped the jab - because if you don’t you have wasted thousands of pounds

I can explain why if you like.

I found that I was a slow loser on Wegovy and stopped within a few kg of my goal weight, which should have been slightly lower to get me into a healthy BMI but I did not want to stay on the WLI due to fatigue and tiredness.

The first six months I managed to keep the weight off, but I found in the second half of the year, when the inevitable stress hit, that my weight did start to creep up again.

I wish I'd had a better 'cushion' from which to start.

I have currently regained half of what I lost- which was not a huge amount, over 5kg, but enough that I'm annoyed about it.

I am currently back on dieting/calorie counting without the WLI.

I'm happy that I'm at a lower weight than before, and losing that 5-6kg has stayed off, I'm not so happy I didn't manage to keep it all off, but I am being kind to myself and understanding that unfortunately my body was 'happier' at the slightly higher weight.

As to why I don't constantly live on a calorie controlled diet, I would have thought that was obvious- you only need a couple of dinners out with friends, night out with partner and Christmas. I wasn't drastically over-eating, but the level of calorie restriction needed to lose is quite high, and I couldn't keep that up indefintely.

I hope by being honest, and realistic, this helps someone else. The key thing I would do, if I didn't struggle so much on the jabs, is leap in if I put on more than 2kg, and restart them.

I am happy I took them though, otherwise likely I would be the same weight as before, or even higher.

lovealongbath · 28/01/2026 11:35

LivingInMinecraft · 28/01/2026 11:23

So people are actually hearing voices in their head “chattering” about food? This sounds really disturbing, more like a neurological disorder.

Yes! On a bad day, it can be constant.

Clefable · 28/01/2026 11:41

LivingInMinecraft · 28/01/2026 11:23

So people are actually hearing voices in their head “chattering” about food? This sounds really disturbing, more like a neurological disorder.

Food noise is basically a constant narrative in you head around food, appetite, hunger. Most people (not all) have an internal voice narrating thoughts, and for some people that narration is very heavily food-oriented.

Thoughts heavily revolve around food: when is the next food, what is the next food, can I wait till X time?

Constant anxiety around food: will this portion be enough? What if I’m still hungry? Is this too much food?

Guilty thoughts: I’ve eaten this bad thing so I won’t eat anything else today; then inevitably spending the next few hours fretting about being hungry, eventually eating something again and the cycle continues.

I don’t really have it any more, I don’t think about food much now, my internal narrative is thankfully more about other stuff, but when I was struggling with my weight my inner voice was very much based around food and hunger.

SilenceInside · 28/01/2026 11:41

@LivingInMinecraft if you think having an internal voice and an internal conversation with yourself is some kind of disorder? I think for most people that’s pretty normal, except that it isn’t constantly about food and not so constant perhaps. For me, being on Mounjaro shuts that all up, mostly, which to me indicates it’s driven in part by the hormonal system related to feeling full and hunger. Which as someone who was morbidly obese, that system was clearly not doing what it “should”.

Alltheyellowbirds · 28/01/2026 12:06

LivingInMinecraft · 28/01/2026 11:23

So people are actually hearing voices in their head “chattering” about food? This sounds really disturbing, more like a neurological disorder.

It’s not “hearing voices”, it’s your own voice 🙄

You have thoughts inside your head right? You think things like “must remember to do a load of laundry when I get home” or “I wonder if there’s a good movie on TV”.

Well it’s that same internal voice, but for people with food noise a huge percentage of those thoughts are around food and eating.

MollyFeather · 28/01/2026 12:09

I’d go as far as to say that nobody is actually maintaining yet, you’d be deemed to have maintained after 2 years plus

Lollylavender · 28/01/2026 12:15

lovealongbath · 28/01/2026 08:19

Google sums it up perfectly……

Food noise is not simply a lack of willpower, but rather a complex, often biological, issue rooted in brain chemistry, genetics, and hormones. It represents a persistent, involuntary, and intrusive mental chatter about food that drives eating behaviors beyond physical hunger, making it a medical or physiological issue rather than a moral failing.

Have You tried intermittent fasting? Just don’t eat anything in a 12-16 hour time window. And don’t buy any ultra processed or other unhealthy foods so that you’re not tempted.

northernlight20 · 28/01/2026 13:06

Lollylavender · 28/01/2026 12:15

Have You tried intermittent fasting? Just don’t eat anything in a 12-16 hour time window. And don’t buy any ultra processed or other unhealthy foods so that you’re not tempted.

haha, im sure shes never thought of that right 🙄. seems some of you think that people who struggle with weight are stupid.

Disturbia81 · 28/01/2026 13:11

northernlight20 · 28/01/2026 13:06

haha, im sure shes never thought of that right 🙄. seems some of you think that people who struggle with weight are stupid.

Yes I haven’t met an overweight person who doesn’t know what to do. It’s not about a lack of knowledge.

HangryBrickShark · 28/01/2026 13:14

From what I've read the tablets will be available in the first half of this year.

But in order to be eligible for these from one provider named as Chemist4U, you must be 18 years or older and:

  • be medically obese (have a BMI of over 30)
  • or be overweight with weight-related issues (a BMI of over 27 and a condition like: high cholesterol, high blood pressure, or type 2 diabetes)

Trouble is as most of us have lost weight on Mounjaro/Wegovy or a combination of both, we won't be over the BMI now. Inever had any of the weight related issues but I was over 8 stone heavier than I should have been. I've lost 3st 8lb so far and plan to stay on for life if I can.

DeftGoldHedgehog · 28/01/2026 13:22

You might be able to transfer if those are the requirements though. As you can between Mounjaro or Wegovy.

DeftGoldHedgehog · 28/01/2026 13:42

The amount you eat is important whatever time window you eat it in.

Yes, most days I find that starting to eat at about 11am onwards helps as eating earlier just makes me eat more overall, it just seems to set off my appetite. But I don't want to be too prescriptive about evening and turn down dinner invitations as it's too late, or worry about eating pasta at 9pm after I've been to the gym or yoga class. Or worry about having a milkshake before my 8am yoga class if I feel like it. So I couldn't stick religiously to IF as my life isn't that regimented.

Lollylavender · 28/01/2026 13:56

DeftGoldHedgehog · 28/01/2026 13:42

The amount you eat is important whatever time window you eat it in.

Yes, most days I find that starting to eat at about 11am onwards helps as eating earlier just makes me eat more overall, it just seems to set off my appetite. But I don't want to be too prescriptive about evening and turn down dinner invitations as it's too late, or worry about eating pasta at 9pm after I've been to the gym or yoga class. Or worry about having a milkshake before my 8am yoga class if I feel like it. So I couldn't stick religiously to IF as my life isn't that regimented.

Interesting, as I would never eat pasta after 9pm, however hungry I was. It would spike my blood sugar and disrupt my sleep. I would rather go to bed hungry and look forward to breakfast instead.

DeftGoldHedgehog · 28/01/2026 14:17

Lollylavender · 28/01/2026 13:56

Interesting, as I would never eat pasta after 9pm, however hungry I was. It would spike my blood sugar and disrupt my sleep. I would rather go to bed hungry and look forward to breakfast instead.

Well, sometimes I have to eat my dinner after 9pm, and sometimes it's pasta. My yoga class on a Monday is 7.45pm - 8.45pm and I don't eat before it other than a light snack about 5pm as yoga on a full stomach doesn't work. On a Tuesday I'm back from the gym about 8pm so again dinner is late. I sleep absolutely fine and certainly wouldn't sleep well if I was hungry. It would be ridiculous not to eat and refuel my body. I have never suffered from blood sugar spikes or problems even though I have PCOS.

FlyHighLikeABird · 28/01/2026 14:22

I can't sleep if I'm hungry, it would keep me awake all night!

Wickedlittledancer · 28/01/2026 14:25

LivingInMinecraft · 28/01/2026 11:23

So people are actually hearing voices in their head “chattering” about food? This sounds really disturbing, more like a neurological disorder.

Curious question. You have no thoughts inside your head? None at all? Are you being disingenuous or really there are no thoughts in your head?

As the voices are really just another name for thoughts. What people are saying is they have constant thoughts about food; there is a dairy milk in the cupboard I really want it, I will only eat half, I will eat it In hour, I fancy a Chinese, how much should I order, should I now have icecream, but I’ve eaten so much today, god I want some crisps. it’s just thoughts of food, eating, not eating, how much to eat, when to eat, what to eat.

grangehilltuba · 28/01/2026 16:24

I haven’t. I took them for about six months, still had about 3 stone to lose, but ran out of money and had to stop. I initially regained a small amount of weight, but then started losing it again, and have been consistently (albeit very slowly at about a pound a week) been losing weight ever since I stopped about 7-8 months ago without consciously dieting, although i guess I must have developed healthier habits. I eat more than I did on the medication (hence losing weight slower) but my appetite just never went back to its pre-medication state. I appreciate I’m possibly an outlier though.

BlueLimes · 28/01/2026 16:48

@Lollylavender I think you said you’re not on WLI? Sone of us have been in a dieting cycle for decades - it’s not as simple as will power, not eating pasta after 8pm etc. people have complicated lives, relationships with food and health issues. I’m sure you don’t mean to but you’re coming across as lecturing us a bit.

northernlight20 · 28/01/2026 17:15

BlueLimes · 28/01/2026 16:48

@Lollylavender I think you said you’re not on WLI? Sone of us have been in a dieting cycle for decades - it’s not as simple as will power, not eating pasta after 8pm etc. people have complicated lives, relationships with food and health issues. I’m sure you don’t mean to but you’re coming across as lecturing us a bit.

I know you’re giving her the benefit of doubt, but I have a feeling she knows exactly what she’s doing. The wli board is full of people who have never taken the jab, never had a weight problem, lecturing those of us on it on how we’ll all have problems in 20yrs time, and pile it back on when we stop. Rinse and repeat.

BlueLimes · 28/01/2026 17:30

northernlight20 · 28/01/2026 17:15

I know you’re giving her the benefit of doubt, but I have a feeling she knows exactly what she’s doing. The wli board is full of people who have never taken the jab, never had a weight problem, lecturing those of us on it on how we’ll all have problems in 20yrs time, and pile it back on when we stop. Rinse and repeat.

The tone definitely feels off 😔

It does feel like some are almost gleeful about people regaining.

Lollylavender · 28/01/2026 17:50

BlueLimes · 28/01/2026 17:30

The tone definitely feels off 😔

It does feel like some are almost gleeful about people regaining.

I am sorry if I’ve said anything that comes across as gleeful or lecturing.

I genuinely believe what I say (including going to bed hungry rather than eating late - this is what our ancestors often did due to lack of food) but I will happily leave this discussion if my comments are seen as unhelpful.

Alltheyellowbirds · 28/01/2026 18:00

northernlight20 · 28/01/2026 17:15

I know you’re giving her the benefit of doubt, but I have a feeling she knows exactly what she’s doing. The wli board is full of people who have never taken the jab, never had a weight problem, lecturing those of us on it on how we’ll all have problems in 20yrs time, and pile it back on when we stop. Rinse and repeat.

Yes.

I do think some of them genuinely feel they’re helping by sharing their skinny person wisdom, and it doesn’t occur to them that we already know everything they’re saying. That actually, no-one knows more about this stuff than those who’ve been battling it for years, read everything there is to read and tried all the diets under the sun.

But then there are also those who just feel superior because they’re slim and get a kick out of talking down to the fatties.

drusilla49 · 28/01/2026 18:05

pouletvous · 25/01/2026 08:50

See , this puts me off starting. I cant afford to take the jab forever

theres no way i can run 5km three times a week nor stick to 1500 cals

spunds like a tough regime

5k three times a week is really not excessive. It’s just a good level of exercise

TorroFerney · 28/01/2026 18:26

Disturbia81 · 26/01/2026 16:20

Exactly. I don’t understand why people think it’s a magic wand that will work forever. Every human being has to work at keeping a healthy weight.

From what I understand people to say is that their "food noise" is worse than say my food noise as a slim person so whereas I can be bloody starving or would kill for a chocolate I can have a word with myself and just not eat the thing and put up with the pangs whereas a lot of people on WLI say that would have not been possible for them. So i assume coming off the drugs, that pre drugs food noise will be too loud to stop so one would have no option but to give into it and eat more than needed.

Overthemoun · 28/01/2026 18:42

Thanks for the positivity! I’m slowly going down the doses from 7.5 to 2.5 now and still maintaining and feeling in control. I hope to also be a success story.

I would be happy to stay on 2.5 if it were free tbh but hoping one more pen to eke it out, jabbing fortnightly or similar rather than cold turkey will give me the best chance

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