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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Coming off the Jabs - please tell me what happened?

258 replies

coconuttyz · 24/01/2026 18:12

I’ve been off Mounjaro for 2 months now. I got down to my target and started to worry about the injections so decided to stop - I’ve gained 5lbs in that time.
Currently trying to maintain by counting calories (1350 a day) 10,000 daily steps plus running 5K x3 times a week.
Was anyone able to maintain following a similar pattern?
I’m sure the 5lbs gained has gone straight to my stomach and hips, but otherwise I still feel quite lean.

Any advice and tips welcome!

TIA Flowers

OP posts:
coconuttyz · 27/01/2026 15:02

@maz99I’m 5 foot 6!

OP posts:
AmythestBangle · 27/01/2026 15:05

@thetallfairy yes, 2.5mg per week, and I have neither gained nor lost weight for six months. My provider is happy with maintenance support and I get my 2.5 pen every month, just as I did for the previous six months when I was losing (which I did mostly on 2.5mg, with only about six weeks on 5mg).

maz99 · 27/01/2026 16:47

coconuttyz · 27/01/2026 15:02

@maz99I’m 5 foot 6!

Then with your actvity level 1350 calories probably isn't enough for healthy maintenance

I'm 5'7" and 55
My BMR calculates to 1324 calories and sedentary TDEE 1457 calories
(BMR decreases with age)

If I change the actvity level to Lightly active. (Walking around a good amount, retail jobs. 1–3 hours per week of light exercise.)
Then TDEE = 1632

BMR is important... it is the minimum amount of calories your body needs to function optimally

I used this site to calculate
keto-calculator.ankerl.com/

ShawnaMacallister · 27/01/2026 20:30

coconuttyz · 27/01/2026 15:02

@maz99I’m 5 foot 6!

How did you calculate your TDEE?

thetallfairy · 27/01/2026 21:30

AmythestBangle · 27/01/2026 15:05

@thetallfairy yes, 2.5mg per week, and I have neither gained nor lost weight for six months. My provider is happy with maintenance support and I get my 2.5 pen every month, just as I did for the previous six months when I was losing (which I did mostly on 2.5mg, with only about six weeks on 5mg).

Amazing

Thank you so much

SummerIsComingNowish · 28/01/2026 20:00

Planner2026 · 24/01/2026 20:42

I have been on a low dose of Wegovy (0.25 shot every other week) to maintain my loss since I reached my goal 2.5 years ago.

Is this helping you maintain- as I was thinking of doing similar and tapering down

ResusciAnnie · 29/01/2026 10:06

Was thinking about this on my run this morning (well, I think it was a different, more sneery 'you can't be on WLIs forever!!' thread but that seems to have gone poof)...

I haven’t come off yet but I suspect this is why 1/2/5 year plans are so important.

For me:

YEAR 1:
June 2025 - June 2026
Aim: lose 3 stone

  • have already lost 2 stone - 30lb in 31 weeks so nothing crazy. Categorically couldn’t do that without the jabs, hence taking the jabs in the first place.
  • before I’d even lost any weight my autoimmune inflammation reduced hugely allowing me to:
  • think clearly across the board, including around food choices
  • exercise without pain - have completed c25k which was a completely different experience compared to when I did it off that jabs. SO much less pain and recovery!
  • I'm still eating everything, just far far less and minimal to zero stress eating. It doesn't even occur to me to finish the kids' food. I am resting more without even realising it. The relief is unmatched.
  • finished c25k and doing first ParkRun this weekend.
  • So, I want another stone down by June 2026.

YEAR 2:
June 2026 - June 2027
Aim: ingrain exercise habit and clean up diet. Lose another couple of stone?

  • Sept 2026 DD will be going to school and I will be keeping my work the same, so will have 2 days a week TO MYSELF in which to exercise and prep food etc and get other stuff done meaning the rest of the week will be less stressful across the board. Am currently only ever at work or with the family so I'm looking forward to being less guilt-ridden when taking time for myself
  • find a nice friendly weight lifting place
  • meal prep lots
  • continue running 2-3x a week
  • Great South Run in October 2026
  • Will take discipline not to fill up my 2 free days with work, as a self employed person there is always more to do

YEAR 3-4
A plan will form as these years get closer. These things evolve. I may find a love of team sports (highly unlikely) or I may lose a leg, you know? You never know. We move. We'll see what happens but we're ok.

But by YEAR 5 I plan to not even have to think about things anymore and my life will be set up in such a way to support my new lifestyle. Whether I'm microdosing WLI or not is beside the point. I will have tweaked my food intake needs as I get smaller but also fitter. I have no idea how much I will weigh. If I lose the remaining stone this year, and then the 2 in year 2, I will be down to the smallest I have ever been since age 13, but will still be 'obese'. So who knows where I will end up.

I tend to clump those anti-WLI people into the same categories as either those who would refuse other drugs - immunisations, chemo (and ironically may just eat bananas to heal their cancer etc) - or those who just love to see others fail.

I think a lot of people fail to realise that illness is a huge part of obesity. Some of us are fat because we're ill. Some of us are ill because we're fat. But either way, wtf is wrong with taking medicine to help?

Binus · 29/01/2026 10:11

Was thinking about this on my run this morning (well, I think it was a different, more sneery 'you can't be on WLIs forever!!' thread but that seems to have gone poof)...

Is that the one from a couple of weeks back where the poster started calling everyone kn WLIs bad mothers? It was absolutely batshit if so!

I understand why the mods delete threads that take that much work, but it's a shame in the truly ridiculous ones can't stand, for posterity. I think it might assist some posters in realising the full context these discussions take place in.

SummerIsComingNowish · 30/01/2026 08:00

If anyone likes a podcast- check out Dr Tyna Moore- she believes that women benefit from micro dosing glp1s for inflammation and hormones.
it makes sense anyway- I’ve never felt better in my own body on them and I’m looking into tapering down and micro dosing this year

Placestogo · 30/01/2026 08:49

SummerIsComingNowish · 30/01/2026 08:00

If anyone likes a podcast- check out Dr Tyna Moore- she believes that women benefit from micro dosing glp1s for inflammation and hormones.
it makes sense anyway- I’ve never felt better in my own body on them and I’m looking into tapering down and micro dosing this year

What counts as microdosing? Also “microdosing” might be quite different for someone who had to go up to 15mg to someone who went max 5mg.

how low can you go to retain some benefits in terms of hormones and inflammatiion? Feeling very confused.
i wonder if it is more a case of “whatever works for you” rather than “microdosing”?

SummerIsComingNowish · 30/01/2026 12:09

Placestogo · 30/01/2026 08:49

What counts as microdosing? Also “microdosing” might be quite different for someone who had to go up to 15mg to someone who went max 5mg.

how low can you go to retain some benefits in terms of hormones and inflammatiion? Feeling very confused.
i wonder if it is more a case of “whatever works for you” rather than “microdosing”?

If you listen to her podcast she will give the data and dosages she recommends- less than a starting dose as a micro dose I think
im not sure about mj as I’m on wegovy and the starting dose is 0.25

im planning to start tapering down first though and see how I go

MJsidekick · 31/01/2026 22:54

Sal7252 · 25/01/2026 14:00

I asked whether it could help me lose a similar amount of weight to what people typically achieve on the injections. It did a comparison based on my weight and the average results from the main jabs. It’s said it will take a bit longer based on what’s realistic for me feel full enough but not significantly and I’m loosing about 1. - 2 lb a week at the moment.

I’ve just been checking in with it - telling it when I’m hungry, what I’ve eaten, and how I’m feeling - and it’s helped me work out what to eat and when (I do a coffee, two meals and a small snack). I use it like I’m talking to a person.

I really hate weighing everything, so I don’t. I mostly estimate calories with its help and only weigh certain things, like cheese. It must be fairly accurate. It is a bit agreeable though so if I say I want another coffee for example it sometimes tells me that’s totally understandable because I’m tried/need something warming and we’ll work on it tomorrow so it’s not perfect but the most helpful thing I’ve tried in a while.

It is a bit agreeable though so if I say I want another coffee for example it sometimes tells me that’s totally understandable because I’m tried/need something warming and we’ll work on it tomorrow so it’s not perfect but the most helpful thing I’ve tried in a while.

You can tell it not to be agreeable. You can do that either while you're chatting or in the settings so it stays that way. Tell it to be objective and act like a PT (personal trainer) as well as a friend so that if you want to do something and it thinks it's not healthy, it should tell you not to or atleast warn you about it instead of agreeing fully with you.

You can program the AI chatbots however you want it to respond to you. Agreeable is just its default setting.

Maryb54 · 16/02/2026 15:28

Hosoan · 24/01/2026 21:04

How are you managing this with getting the prescriptions? Who are you with please?

Yes, I’d like to know this too, please.

cupfinalchaos · 16/02/2026 22:49

Solasum · 24/01/2026 20:25

I think the reality is that most adults age 40+ leading a sedentary life probably only need two meals worth of calories per day if they are not going to gain weight.

Edited

I’m in my 50’s and found this to be sadly true. If I eat 3 meals a day I gain even if I’m in the gym 3 days a week.

SnacklessWonder · 17/02/2026 10:15

cupfinalchaos · 16/02/2026 22:49

I’m in my 50’s and found this to be sadly true. If I eat 3 meals a day I gain even if I’m in the gym 3 days a week.

It's so depressing. I look at a carb and I am 2lb heavier!

Now mid-40s, with a sedentary job, my maintenance calories are around 1500.

Over that, and I start to gain so I tend to not eat until late morning/lunch which I suppose is classed as intermittent fasting but it's not intentional, I just find that I can get to lunch easily enough without eating.

StrongLikeMamma · 18/02/2026 20:11

Solasum · 24/01/2026 20:25

I think the reality is that most adults age 40+ leading a sedentary life probably only need two meals worth of calories per day if they are not going to gain weight.

Edited

OP is not being sedentary or eating enough calories

StrongLikeMamma · 18/02/2026 20:13

Op try lifting weights - it’s incredibly good for you and burns loads of calories
Focus on protein, healthy fats and fibre and shed loads of water
If your calorie intake is too low your body might be holding onto fat.

thetallfairy · 27/02/2026 10:44

6.5 stone down

I am over the moon

on 10mg
I find 5 days in the food noise is def there

I am hoping to titrate down as much as I can
I will be on the jabs two years in sept so maybe from now slowly ease myself off?
Not going to lie I have no clue how to even go about all of this

I walk around 2 hours at a fast pace each day
dont eat sugar

love crisps

needs more protein and to do more strength training

anyway tips would be most appreciated

thanks all xxxxx

Lollylavender · 28/02/2026 07:48

cupfinalchaos · 16/02/2026 22:49

I’m in my 50’s and found this to be sadly true. If I eat 3 meals a day I gain even if I’m in the gym 3 days a week.

Surely this will depend more what those 3 meals consist of!

I eat three healthy meals per day, I exercise most days and my weight is stable at a healthy bmi. I’m mid 50s.

cupfinalchaos · 28/02/2026 11:27

Lollylavender · 28/02/2026 07:48

Surely this will depend more what those 3 meals consist of!

I eat three healthy meals per day, I exercise most days and my weight is stable at a healthy bmi. I’m mid 50s.

I guess we all have different metabolisms.

OntheTrainX · 28/02/2026 12:50

TBH I’m 53 and haven’t struggled to keep the weight off. No issues with metabolism.

My struggle is with a temptation to binge but that’s something else.

thetallfairy · 01/03/2026 14:13

my temptation to binge some days is very high

I used to binge eat a lot after leaving an abusive relationship

thetallfairy · 16/03/2026 12:59

so in all reality do most feel that they will be microdosing long term?

thanks all for the tips so far very helpful

SilenceInside · 16/03/2026 13:04

@thetallfairy I plan to continue taking one of the standard doses long term, lowering the dose if I can, and see if I can eventually move off the medication in the longer term. I am prepared to take it long term if necessary. Or restart if necessary. I don't see the point of microdosing a tiny amount of medication as I don't think that it would have any real effect.