Coming off the Jabs - please tell me what happened?

[coconuttyz]

I’ve been off Mounjaro for 2 months now. I got down to my target and started to worry about the injections so decided to stop - I’ve gained 5lbs in that time.
Currently trying to maintain by counting calories (1350 a day) 10,000 daily steps plus running 5K x3 times a week.
Was anyone able to maintain following a similar pattern?
I’m sure the 5lbs gained has gone straight to my stomach and hips, but otherwise I still feel quite lean.

Any advice and tips welcome!

TIA

That’s thing she honestly won’t do any of that. Perhaps for the next month, but there’s a reason she needed the jabs in the first place and I suspect a lot of others are in the same position too.

I lost 3 stone on Mounjaro. Since then, in the past 6 months or so, i got a single 2.5ml pen and injection every couple of months. It stopped my appetite returning and seems sustainable. I looked into if it is dangerous to keep using it longer than the recommended month. It just says on google that it might lose its efficiency so it’s definitely safe. It appears to me that it is just as efficient as ever. I haven’t regained any weight.

I lost 2.5stone on MJ. Kept it off for a year by increasing exercise (running and weights) as well as maintaining food discipline (such as 2 home-made healthy meals per day). Put half a stone on when undergoing IVF treatment. Now back on MJ (lost a stone in 6weeks) and coming off again next week. The time off it was hard. But better for me than paying out for the injections.

I think this is an excellent strategy. I suggested someone look into doing that on another thread a while back and was shot down in flames

It makes perfect sense.

As long as it is noted there is absolutely no therapeutic benefit to a tiny dose several weeks apart, and it is likely psychological only. It’s like saying I’m staving off a heart attack as I take a quarter of an aspirin every six weeks,

Has it be studied and tested?

Who cares if its psychological, lots of things we do for ourselves to make changes are 'psychological'. If it works, it works

But why won’t she exercise or eat healthily? Not only to lose weight but to build muscle and be healthier?!

I stopped in August and have kept it off by avoiding snacks and doing lots of weight training, golf and walking.

No of course not, who on earth would bother to study and test that, 😂

To find out if in fact there is therapeutic benefit. That was the point of my question

Just because something hasnt been studied (yet) it doesnt mean that people arent finding a therapeutic benefit from it that hasnt been scientifically proved.

Well they know there is no therapeutic benefit in 2.5 weekly, so why would they test less?

I stopped for a month and gained a stone. Back on it now! Probably be on it for life, or until I’m too old to care about being fat.

Lets come back in years to come and see.

Not the “Japan” fallacy again 😂

Thank you.
I get mine from “a friend “ like the other poster 😂
It’s been great and I am very happy with my weight loss (I wasn’t massively overweight but wanted to lose weight )

I’ve accepted that I will have to micro dose every so often for the rest of my life

but it’s cheap and worth it for me

I don’t really care what other people think
nothing taste like skinny feels.
( think I got that quote right )

They don't 'know' that at all. Plenty of people experience genuine effective treatment at that dose.

But they do know they have tested it. They even state it, there is no therapeutic effect on the body from 2.5 mg. The first therapeutic dose is 5mg.

I had significant appetite suppression at 2.5mg, I never went higher!!

But that’s not therapeutic.

Came off December 2024, weighing 8st 11.6lb. Am now 8st 5lb. Haven;t been trying to lose weight, just maintain.

This is my plan

I have lost six stone been on them for 18 months

I am on 10mg at the moment so aiming to go low each week and then do it every other week?

Have no idea really to be fair

Op they are def the best thing I have ever done

I was binge eating due to ptsd

I think there is a lot still to be unpicked on how different doses work in different people. I lost all my weight on 3.75mg, 5 was way too strong for me, I could barely eat and it gave me the raging shits, but I lost 5 stone on 2.5-3.75 before I came off. It was definitely having the effects as stated (evidenced when I got Norovirus and threw up recognisable food I’d eaten 24+ hours earlier which was a bit grim!) whereas for other people they need to get up to the higher doses before they notice anything. But even on my first dose of 2.5, within four hours my appetite was gone, I remember thinking how wild it was!

Some people seem to be far more sensitive/super responders while others need to go up to 15mg, and I wonder if that has some influence on how easy it is to come off them. I think there’s probably a lot more to discover!

Some people are classed as super responders and will only ever need lower doses…equally, some people have barely any result from being on the top dose…..there’s always a genetic / individual response to any medication ( …did you know red headed people often need higher doses of analgesia because they respond less!)

I don't think that's quite the right interpretation of the clinical trial data @Wickedlittledancer . What they found was that on 2.5mg there was no statistically significant weight loss, but you can see if you look at the trial data that participants lost weight (on average) during weeks 0 to 4 when they were all on 2.5mg. For example, from the SURMOUNT-1 trial, you can see on the average weight loss graph (figure 1) that after 4 weeks, those on tirzepatide lost around 3% of their starting weight, compared to around 1% for those on the placebo. So clearly the 2.5mg was having an effect and more than the placebo.

Continuing on 2.5mg was not something that was studied, so the lowest dose that is discussed as effective for long term weight loss is 5mg. That's what can be proven to give significant weight loss for the majority, on average. People can and will lose weight on 2.5mg, but not enough on average for it to be considered a dose that people would expect to lose a statistically significant amount of weight on. On average. If you want to call the 2.5mg dose a non-therapeutic dose, you'd still have to acknowledge that everyone on the trials lost weight when on that dose, and that many people will continue to lose weight if they stay on that dose. We don't know how effective 2.5mg is long term, because that dose level wasn't tested in any of the trials and isn't being studied on any of the continuing trials as far as I am aware. It is likely to be somewhere between the placebo and the 5mg curve on the graph I mentioned previously.

You can google, el Lilly state it is a non therapetic dose to to the lack of glyaecimic control.