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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

October '25 Starter - Thread 2

791 replies

jaelato1 · 13/11/2025 10:45

@cheekysausage123I have created another thread (hope you dont mind) as first thread has been closed.

Weighing today but decided not to as its time of the month and I feel very bloated.

OP posts:
Thread gallery
7
Elliebearblues · 16/11/2025 12:23

VioletandMauve · 16/11/2025 08:31

So after 4 weeks on 2.5mg I’ve lost another 2lbs this week making a total of 10.5lbs!! Over the moon with this. Am staying on 2.5 as it’s working really well for me so don’t feel the need to move up any more at the moment.

That’s fabulous x

VioletandMauve · 16/11/2025 13:25

@Elliebearblues - thanks! I know how you feel as I’ve had a terrible cold and cough since Friday am hoping to feel better tomorrow. Difficult to eat at the moment but I think that’s down to the cold and not the Mounjaro!

StrongLikeMamma · 16/11/2025 15:43

Calyx72 · 16/11/2025 12:11

Hellooo again thanks for the new thread and the heads up! I am staying on 2.5 and did jab 8 this morning. My 166lb plateau has stopped, I am now 163lbs which is a relief! I am a size 16 instead of an 18 Grin. Total loss so far is 13lbs so almost a stone in 8 weeks.

I’m so looking forward to being able to wear a smaller size - well done! 👏

Lovesabadboy · 16/11/2025 17:32

Elliebearblues · 15/11/2025 17:20

The first weekend I took the 5mg about 7hrs later I did have stomach cramps which lasted into the next day, then on the Sunday I had sulfer burps and diarrhoea which lasted the day. Not very nice but I kinda guessed I may have some side effects when moving up a dose. Last weekend wasn’t to bad but I did have diarrhoea a few times on the Sunday and touch wood this weekend after my 3rd jab of 5mg has been ok. My stomach has been cramping a bit but that started before the jab, I suffer with IBS and I got a feeling the mushrooms I had Wed/thur didn’t agree with me x

Eeek, those side effects sound a bit unpleasant, but it sounds as though they are easing as each week passes.

I am about to do my 6th jab this evening and I weighed in again this morning (after an interim weigh in on Thursday). I have now lost 11lbs in 5 weeks, so am more than happy with that. This also takes me down into the next stone bracket, which feels like quite a milestone in itself!

Onwards and downwards everyone!

cheekysausage123 · 16/11/2025 18:28

Great work @Lovesabadboy@VioletandMauve@Moosey898@Calyx72@Elliebearblues and amazing on the pjs fitting more comfy too @Elliebearblues!

Also got a cold @VioletandMauve but it’s not affecting my appetite as far as I can work out. 😂

Down 2.8lb this week, 19lb down overall since end of Sept. 🥳 Doing my 8th jab tonight.

Elliebearblues · 16/11/2025 19:51

Lovesabadboy · 16/11/2025 17:32

Eeek, those side effects sound a bit unpleasant, but it sounds as though they are easing as each week passes.

I am about to do my 6th jab this evening and I weighed in again this morning (after an interim weigh in on Thursday). I have now lost 11lbs in 5 weeks, so am more than happy with that. This also takes me down into the next stone bracket, which feels like quite a milestone in itself!

Onwards and downwards everyone!

They weren’t very nice 😩 touch wood I’ve been ok after this Fridays jab (3rd 5mg) a bit of nausea yesterday and today but not to bad

StrongLikeMamma · 16/11/2025 20:26

Jab 5 due tomorrow am 13lbs down.
So it’s working well.
Sticking with 2.5 as I feel the effects so strongly.
The fatigue is a bit annoying - I went to the gym yesterday and have been completely useless today.
Am really trying hard to meet my protein goals.
I am really intrigued to see what month 2 brings.

putthehamsterbackinitscage · 16/11/2025 20:37

StrongLikeMamma · 16/11/2025 20:26

Jab 5 due tomorrow am 13lbs down.
So it’s working well.
Sticking with 2.5 as I feel the effects so strongly.
The fatigue is a bit annoying - I went to the gym yesterday and have been completely useless today.
Am really trying hard to meet my protein goals.
I am really intrigued to see what month 2 brings.

Well done Mamma!

that’s a great loss! You are doing fab!

I’ve got jab 5 due Wednesday if I stick to 7 days this time (have been doing 5/6 days as suppression seemed non existent). I’ve got a 5mg pen waiting in the fridge but will do extra dose from 2.5mg first….

Not sure yet whether I will jump to 5 or not next week. I’m going to order my 3rd one tomorrow though as medexpress will open my order window and I want to try to build stock.

no real side effects so far …. A bit constipated but using Movicol lead to loose stools so going to just have to take the drier days…. Suppression wears off on day 5 but that’s a chance to learn to manage food intake without help as well.

Elliebearblues · 16/11/2025 21:21

StrongLikeMamma · 16/11/2025 20:26

Jab 5 due tomorrow am 13lbs down.
So it’s working well.
Sticking with 2.5 as I feel the effects so strongly.
The fatigue is a bit annoying - I went to the gym yesterday and have been completely useless today.
Am really trying hard to meet my protein goals.
I am really intrigued to see what month 2 brings.

13lbs is amazing, when I first started the jabs I felt fatigued but now that’s the only symptom I don’t get 😂. I’ve been rubbish at protein goals lately but am trying to get a bit more in slowly. Hoping to get back to the gym next week, it’s the nausea this week that’s affecting me the most x

Clumsykitten · 16/11/2025 22:04

I’m having a conundrum. I should be doing my second 5mg jab on Tuesday… but I’m trying to work out whether to stick at 5mg or drop back to 2.5. I have not enjoyed this week. Plus I have a horrible cold.

Elliebearblues · 17/11/2025 07:11

Clumsykitten · 16/11/2025 22:04

I’m having a conundrum. I should be doing my second 5mg jab on Tuesday… but I’m trying to work out whether to stick at 5mg or drop back to 2.5. I have not enjoyed this week. Plus I have a horrible cold.

I would say it depends on, so you have good supression and weight losses on 2,5mg? If so yes I’d drop back down, but remember when you go back up to 5mg you may get side effects again. This week has been so much better on 5mg but taken until this 3rd jab to not feel as rubbish xx

Moosey898 · 17/11/2025 08:55

Clumsykitten · 16/11/2025 22:04

I’m having a conundrum. I should be doing my second 5mg jab on Tuesday… but I’m trying to work out whether to stick at 5mg or drop back to 2.5. I have not enjoyed this week. Plus I have a horrible cold.

I would do a second jab at 5mg to see if the symptoms eased as your body gets used to it. It takes time for things to settle at higher doses sometimes.

jaelato1 · 17/11/2025 08:59

@cheekysausage123 @StrongLikeMamma @Elliebearblues Amazing losses! Finally did my weigh in and I am 1.5lb lighter,

Has anyone noticed any changes with their period? This month mine seem to be lighter but longer, it would stop then show up again - it's pissing me off.

OP posts:
putthehamsterbackinitscage · 17/11/2025 12:04

Just placed another order with Medexpress - decided to stick with 5mg for pen3 although I won’t start pen2 till next week…

I’ve lost a total of 11 lbs in 3 weeks so I’m happy with my losses although I brought doses 3 and 4 forward by 1-2 days as felt suppression had worn off. Extra dose this week then decide what to do - full 5mg or not.

@jaelato1sorry - can’t help as I am menopausal.

Calyx72 · 17/11/2025 14:52

jaelato1 · 17/11/2025 08:59

@cheekysausage123 @StrongLikeMamma @Elliebearblues Amazing losses! Finally did my weigh in and I am 1.5lb lighter,

Has anyone noticed any changes with their period? This month mine seem to be lighter but longer, it would stop then show up again - it's pissing me off.

Edited

I’m perimenopausal but yes some spotting now and again between periods

putthehamsterbackinitscage · 18/11/2025 16:17

Weigh in last night - 11lbs since 25th October ~3.5 weeks. I have slowed down since week 1 but I’m happy with that as I am not restricting what I eat and drink more than how much… definitely eating less junk but nothing is completely off limits as I have previously lost weight by cutting things out or vlcd and this time I want to make it sustainable.

i’ve taken my 5th dose earlier using a syringe - got about 0.8 ml out so roughly 3.33 mg dose and will see how that goes before deciding on full 5mg next. So far, no side effects - will see how the next few days go!

DakotaFanny · 18/11/2025 16:55

I probably shouldn’t really be celebrating this but after 5 weeks of 2.5mg and NO side effects or visible benefits, I moved up to 3.75mg on Sunday and today I had sulphur burps- yaaaaay! Go me!!! 😂😂😂😂

putthehamsterbackinitscage · 18/11/2025 16:56

@DakotaFanny I think that’s worth celebrating! Sometimes we need some reassurance even if it is negative 😂😂😂😂

jaelato1 · 18/11/2025 18:51

@DakotaFanny you cracked up me lol needed the laugh, been down with cold since yesterday.

OP posts:
Meandmypooch · 18/11/2025 20:12

Week 7 weigh in after a 3.75mg jab and funnily enough there was more food noise than on the 2.5mg so trying 5mg
Still lost 1.2 kg though
SW 129.1 kg
CW 116.1 kg
TW 100 kg

Lost just over 2 stone in total so well chuffed 😄

Clumsykitten · 18/11/2025 20:28

I’m debating 2.5/3.75/5mg this evening. Definitely got the food cravings and noise back today… so I’m wondering if lower dose/higher frequency might work for me in the long run….

Clumsykitten · 18/11/2025 20:29

Also…. Er…. Congratulations @DakotaFanny😆

StrongLikeMamma · 18/11/2025 21:16

DakotaFanny · 18/11/2025 16:55

I probably shouldn’t really be celebrating this but after 5 weeks of 2.5mg and NO side effects or visible benefits, I moved up to 3.75mg on Sunday and today I had sulphur burps- yaaaaay! Go me!!! 😂😂😂😂

Congrats! 🙌

DakotaFanny · 18/11/2025 21:33

Thanks everyone! 😂 I presume now that I will wake up 4 stone lighter tomorrow as well… ??

Elliebearblues · 19/11/2025 07:42

DakotaFanny · 18/11/2025 16:55

I probably shouldn’t really be celebrating this but after 5 weeks of 2.5mg and NO side effects or visible benefits, I moved up to 3.75mg on Sunday and today I had sulphur burps- yaaaaay! Go me!!! 😂😂😂😂

Those Sulfer burps are horrible x