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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

September 25 starters thread2 - gliding into autumn

979 replies

outofofficeagain · 04/10/2025 19:36

We go (vy) again …

OP posts:
Thread gallery
31
Georgelassosthemoon · 24/10/2025 10:40

Weigh day for me too, 2lbs off this week. However it’s definitely not linear for me.

SW 17.13
CW 16.11
TW 16.5

I’m not setting a long term target - 12 stone 7 gets me out of the overweight range for BMI but that seems impossible. I’d be happy with about 13.

wodantimbercoaster · 24/10/2025 10:43

8th jab last night, went for 2.5mg again from my 5mg pen. Weigh in day this morning. I nearly didn't do it, as I've felt like I haven't been as good this week (no gym, drank much less water, have been out a couple of times and eaten more than I have been plus had quite a bit more alcohol). Plus I'm going on holiday for a week today, so bound to be slightly more relaxed. However, I did weigh myself and I somehow lost 3lbs! Which is odd, as I've been losing a steady 2lb each week since week 3. It was a nice surprise. Weight loss journeys are definitely weird aren't they?! Anyway, that's 22lb in 7 weeks. I'm very happy with that!

outofofficeagain · 24/10/2025 11:08

I’m about to go on a week’s
all inclusive. Wish me luck!

Are you all getting 5 or 6 weeks out of 3.75 on a 5 pen? Or wasting the rest?

OP posts:
UnimaginableWindBird · 24/10/2025 11:28

Good luck. I've got a 3 day, 2 night conference coming up which is a bit nerve-wracking, but part of this journey is going to be about making the best choices in situations where I don't have a lot of control. I checked, and at least the hotel has a gym.

MoreIcedLattePlease · 24/10/2025 12:45

outofofficeagain · 24/10/2025 11:08

I’m about to go on a week’s
all inclusive. Wish me luck!

Are you all getting 5 or 6 weeks out of 3.75 on a 5 pen? Or wasting the rest?

Have the best time! Don't forget, a small gain after a holiday is just temporary and usually bloat!

Definitely no wastage here, I can't afford to throw meds away!! I've used all my clicks in my 5mg pen now, but have the golden dose left. Used it for 3.75 pretty consistently.

I have a 7.5mg pen in the fridge now, not sure whether to do half dosing and stick at 3.75mg, or move up to 5mg. The food noise is creeping up, suppression creeping down and the side effects have fully settled now. I'll see how I get on this week.

So far my journey looks like:

W1: 2.5mg
W2: 2.5mg
W3: 2.5mg
W4: 2.5mg
W5: 2.5mg (GD)
W6: 3mg
W7: 3.75mg
W8: 3.75mg
W9: 3.75mg
W10: 3.75mg

I've lost 24lb in total, but due to weigh on Sunday and hope that will drop again.

I'm not in any sciatica pain anymore, thankfully. I've also got to the point where I can sit down again! Big deal, because I was struggling to eat at all as I simply couldn't stay upright long enough. Slowly getting back to activity now through walking, but I'm frustrated that this episode may have affected my progress.

I've also switched from Juniper to Bupa today for the rest of my journey. They are in line with the cheapest discount prices on monj.co.uk up to 10mg (I don't intend to go above this) but also include monthly calls with a health coach which I'm hoping will help guide me through the changes I can make without setting off some form of joint issue again!

Congrats to all this week on weight loss - funny how many of you seem to have had a 3lb week!

Ihateslugs · 24/10/2025 13:05

Elliebearblues · 24/10/2025 08:51

Hi all, did anyone get supression on 2.5mg?
I’ve been on MJ for 3 weeks so far losing weight very slowly - 4.2lb in 3 weeks not a great load but I suppose at least it’s a loss considering I don’t have any food supression

2.5mg had no impact on me, I did lose a few pounds though as I was in calorie deficit. I’ve just begun feeling some loss of appetite in that I cannot eat as much, not even salad, now I’m on 5mg. Still getting hunger pangs though and was yearning a gin and tonic last night but my will power is good as I was dieting for a few months prior to using Mounjaro.

Ihateslugs · 24/10/2025 13:29

Weigh in day for me but I postponed my jab from yesterday until today as I’m going out tonight and don’t want the usual side effects to hit me while I’m out! I’ll wait until I get back home this evening as I’ve not got anything planned for this weekend.

SW 17.7st. 248lb
CW 16.8st. 236.5lb
TL 11.5lb
Lost 3.5lb

This is over 6 weeks, I’m due to take my 7th jab tonight. I did have a week with no loss and a couple with just 1lb so I was pleased with a 31/2lb loss this week.

I have now lost 32.5lb in about 5 months through dieting before going on Mounjaro ( am guessing at length of time as I have no idea when I first started my weight loss journey as I didn’t have any scales at first and did not record the dates I weighed once I bought the scales!).. I’m basing my total loss on what I weighed three years ago when I last saw a Consultant to discuss knee replacement surgery and he advised me to lose weight first. I know I put weight on due to binge eating crisps, cakes, biscuits, bread, chocolate pies etc, often in the middle of the night and also drinking far too much gin!

Im hoping to see the Consultant again in a couple of weeks so I hope I’ve done enough!

Chopsy123 · 24/10/2025 13:53

I’m on 2.5mg and took my 9th dose today. I took the golden dose from my first pen with a syringe and intend to do the same again next Friday.

I’ve bought a 5mg pen and will stick with 2.5mg or possibly move up to 3.75mg. I haven’t decided yet.

I still get enough suppression to not over indulge towards the end of the week so I’m happy with a slower weight loss 1-2lb a week on average.

My weigh in day is Saturday mornings.

We have family visiting next week so it will be interesting to see how that affects things. DIL is very tiny (Japanese) and eats very healthily and tends to ask awkward direct questions sometimes. 😂

I haven’t lost enough weight for it to be noticeable so I’m hoping I’ll stick to eating less and either she won’t notice at all or I’ll tell her I’m dieting again….! (Which is true 🤷🏻‍♀️)

Elliebearblues · 24/10/2025 14:21

Ihateslugs · 24/10/2025 13:05

2.5mg had no impact on me, I did lose a few pounds though as I was in calorie deficit. I’ve just begun feeling some loss of appetite in that I cannot eat as much, not even salad, now I’m on 5mg. Still getting hunger pangs though and was yearning a gin and tonic last night but my will power is good as I was dieting for a few months prior to using Mounjaro.

Well done, I’ve been pretty good on the willpower front, but the fact that I’m losing maybe around 1lb and week and not really getting supression makes me think after next weeks jab that I should move up a dose. Did you go straight to 5mg?

Atalosswhat2do · 24/10/2025 15:18

@Chopsy123 thank you I really appreciate that!

I went from 10st to 15st 6lb in 4 years after almost dying, and subsequently being left ‘disabled’ during the birth of my youngest son in Nov 2015.

My physical and mental health were horrendous, I tried hard to lose weight but the lack of mobility and my low self worth always got the better of me. I did manage to get just over 3st off between 2021 & 2024, but could never get any further. 😞

MJ has completely transformed my whole world in 6 weeks mentally & physically.

You CAN absolutely get there, I’m going to be keeping an extra lookout for your updates, and will be cheering you along. 🫶🏻

Elliebearblues · 24/10/2025 16:03

Chopsy123 · 24/10/2025 13:53

I’m on 2.5mg and took my 9th dose today. I took the golden dose from my first pen with a syringe and intend to do the same again next Friday.

I’ve bought a 5mg pen and will stick with 2.5mg or possibly move up to 3.75mg. I haven’t decided yet.

I still get enough suppression to not over indulge towards the end of the week so I’m happy with a slower weight loss 1-2lb a week on average.

My weigh in day is Saturday mornings.

We have family visiting next week so it will be interesting to see how that affects things. DIL is very tiny (Japanese) and eats very healthily and tends to ask awkward direct questions sometimes. 😂

I haven’t lost enough weight for it to be noticeable so I’m hoping I’ll stick to eating less and either she won’t notice at all or I’ll tell her I’m dieting again….! (Which is true 🤷🏻‍♀️)

That’s great you’ve managed to lose on the lower dose definitely cheaper for you also. I’m going to do 2.5 Monday then move up the week after. Just unsure whether to go to 3.75 or 5. Decisions decisions. Hope the family visiting next week goes well

Ihateslugs · 24/10/2025 18:09

Elliebearblues · 24/10/2025 14:21

Well done, I’ve been pretty good on the willpower front, but the fact that I’m losing maybe around 1lb and week and not really getting supression makes me think after next weeks jab that I should move up a dose. Did you go straight to 5mg?

Yes I did, I get my pens from a local pharmacy and have a check in with the pharmacist while there. I’ve not liked to discuss adjusting the doses as I’m not sure that he will approve! But I might raise it next week when I go as dropping to 3.75 is one option to hopefully ease the side effects.

JustPickleRick · 24/10/2025 19:54

Asda were so quick today approving a new 2.5 pen for me. I put an order in and sent a message explaining that i wasn't quite ready for the 5mg pen sat in my fridge so could I go back down to 2.5. Approved within a couple of hours so I can collect tomorrow. Tonight is usually my jab night so happy to wait 1 more day :)

Pinkbox · 24/10/2025 21:50

Those who are doing doses of 3.75, how many do you get out of a 5mg pen and do you therefore use it past the 30 day mark? Is there also a ‘golden dose’ option in that size? Thanks.

Chopsy123 · 25/10/2025 08:13

@Pinkbox I’ve just bought my first 5mg pen and will start using it in a couple of weeks time.

I’m working on the assumption that;

4 doses x 5mg = 20 mg total medication in the pen (plus extra for priming)

20mg divided by 2.5mg doses = 8 doses minimum

20mg divided by 3.75mg doses = 5 doses minimum.

I haven’t decided whether to go up to 3.75mg yet but definitely don’t want to jump to 5mg so I will be using the pen past it’s 30 day recommended mark.

I took the golden dose from my first 2.5mg pen and will do the same with the current pen next week and will start on my 5mg pen on 7th November. I’m happy to take the risk with going over 30 days but you need to decide what you feel comfortable doing.

Until I get to that point, I don’t know how much liquid is left over in the latest batch of 5mg pens but there was talk of it being less than a full dose now although, if I stick with 2.5mg dose, there might be enough for at least one extra dose but that will take me to the pen being used for 56 days on 2.5mg.

Chopsy123 · 25/10/2025 08:20

Weigh in day for me after 9th jab last night.

SW. 14st 12lbs
CW 13st 6.5lbs
GW1. 12.5st and hope to achieve this by Christmas.

GW - around 10 stone.

lost 2.5lbs this week and very happy with that. ☺️

OneDayIWillLearn · 25/10/2025 08:47

@Pinkbox I didn’t initially mean to be using 3.75mg but when it came to starting my 5mg pen, it was week with a special weekend away in it and I just didn’t want to take a risk with ruining it! So I did 3.75mg to play it a bit safe.

But actually I got pretty strong suppression on 3.75mg and wouldn’t have really wanted more (especially given another albeit less special weekend away!) so did another week of 3.75mg week. I’ll probably do the same again next week but I might go up to 5mg before I get to the end of the pen depending how the suppression goes. I am comfortable going beyond 30 days if it works out like that, but agree with @Chopsy123 you've got to make your own mind up about that.

Domino’s went alright last night - we got thin crust and I had four slices and strawberries plus a little bit of ice cream for pudding and it sat fine.

Pub lunch coming up next, the menu looks quite heavy from a first glance! I need to take another look….

Atalosswhat2do · 25/10/2025 09:54

Chopsy123 · 25/10/2025 08:20

Weigh in day for me after 9th jab last night.

SW. 14st 12lbs
CW 13st 6.5lbs
GW1. 12.5st and hope to achieve this by Christmas.

GW - around 10 stone.

lost 2.5lbs this week and very happy with that. ☺️

Brilliant, well done! 👏🏼 You can absolutely smash that first target over the next 9weeks! 💪🏻

Ihateslugs · 25/10/2025 11:36

I went to a pot luck type supper with a WI group last night, the theme was American food so rather rich and high calorie! I’d not eaten much all day in anticipation, I had a homemade high protein cookie for breakfast and two hard boiled eggs with rice cakes then some prunes and a kiwi - still eating high fibre foods as I’ve not had a poo since my bout of diarrhoea after my 6th jab.

I helped myself to a small amount of most of the dishes and was really surprised at how little I was able to eat, I did not feel over full, just did not want anymore! I did eat more of the desserts, one of which I took, a peanut butter and jam cheesecake which was really high calories! I found it easier to eat the sweet things than the savoury ones which surprised me. All in all though I ate a lot less than I usually would which I was pleased about and I’m beginning to think the Mounjaro is now having some impact. I still had way more calories than I should have but I’ll not eat much today to compensate.

I had my 7th jab last night and and am now waiting for the usual side effects, I’m not going out socially for a couple of days so can stay near my bathroom!

Kazzaa46 · 25/10/2025 16:50

@Ihateslugs its great to hear it’s finally starting to work for you.

@Pinkbox I’m on 3.75mg, 3rd dose tomorrow. I’m hoping to be able to dial 5 doses on it based on the number of clicks it allows but I’ll report back when I get to that stage if I have any issues. Dose 6 would be my GD and I can tell from my pen size it’s an old style one so should have enough left. I’m undecided whether I’ll do the GD at this stage though, more due to my needle anxiety and not liking the thought of using a separate syringe. I’ve only just managed to use the pen needle without having a panic attack 😆

SoUncertain · 25/10/2025 17:11

outofofficeagain · 24/10/2025 11:08

I’m about to go on a week’s
all inclusive. Wish me luck!

Are you all getting 5 or 6 weeks out of 3.75 on a 5 pen? Or wasting the rest?

You can have five doses within the 30 days limit (day 0, day 7, day 14, day 21, day 28). Tbh I'll take six because it's SO expensive and I'm not worried about an extra five days.

Best of luck with all inclusive! I had a weekend away with food included and found i could just have smaller portions but still enjoy treats etc. and lose weight. Are you planning to stay in your calorie goal or just enjoy yourself? I think either is perfect tbh. I want a holiday!

SoUncertain · 25/10/2025 17:25

Ihateslugs · 24/10/2025 13:29

Weigh in day for me but I postponed my jab from yesterday until today as I’m going out tonight and don’t want the usual side effects to hit me while I’m out! I’ll wait until I get back home this evening as I’ve not got anything planned for this weekend.

SW 17.7st. 248lb
CW 16.8st. 236.5lb
TL 11.5lb
Lost 3.5lb

This is over 6 weeks, I’m due to take my 7th jab tonight. I did have a week with no loss and a couple with just 1lb so I was pleased with a 31/2lb loss this week.

I have now lost 32.5lb in about 5 months through dieting before going on Mounjaro ( am guessing at length of time as I have no idea when I first started my weight loss journey as I didn’t have any scales at first and did not record the dates I weighed once I bought the scales!).. I’m basing my total loss on what I weighed three years ago when I last saw a Consultant to discuss knee replacement surgery and he advised me to lose weight first. I know I put weight on due to binge eating crisps, cakes, biscuits, bread, chocolate pies etc, often in the middle of the night and also drinking far too much gin!

Im hoping to see the Consultant again in a couple of weeks so I hope I’ve done enough!

Edited

I'm so glad it's starting to work for you :) x

SoUncertain · 25/10/2025 17:39

I'm finding suppression pretty good on 3.75mg. I have been ill with a cold for a week and a half now which is making me feel bleh, but I don't think it's the MJ. Need to make sure I have more healthy options on hand. I haven't wanted to go for shopping this week so not been the healthiest week. Still lost some weight (official weigh in tomorrow), but that's the suppression rather than my hard work.

outofofficeagain · 25/10/2025 18:02

Actually @SoUncertainthe all inclusive is going well so far.

DS (16) is getting his money’s worth and so am I as I’m eating mainly protein.

eggs and ham for breakfast, barbecue meat for lunch and didn’t load my plate with chips. Also managed to resist the pastries.

it’s actually easier than at home!

OP posts:
JustPickleRick · 25/10/2025 19:20

outofofficeagain · 25/10/2025 18:02

Actually @SoUncertainthe all inclusive is going well so far.

DS (16) is getting his money’s worth and so am I as I’m eating mainly protein.

eggs and ham for breakfast, barbecue meat for lunch and didn’t load my plate with chips. Also managed to resist the pastries.

it’s actually easier than at home!

That sounds perfect 😍