Mounjaro February to April 24 starters - Thread 5

[DesparatePragmatist]

Continuing the journey for those of us who have been on MJ since early 2024. Previous thread here:

https://www.mumsnet.com/talk/weight-loss-injections/5262448-mounjaro-february-to-april-24-starters-thread-4?page=39&reply=146714858

I know this thread isn’t all that active but I thought I’d check back in regardless. I still really enjoy seeing how everyone’s getting on.

I still can’t believe I’ve lost over eight stone. It’s like a dream come true. My body has firmly decided my weight should be 10 stone (size 10/12). Even at 15mg and a very restrictive calorie intake I held solid for months and months and months so I bit the bullet and very slowly titrated down.

I’m now on 5mg and the oddest thing has happened, I find it’s too strong and it gives me the worst D&V…just like when I first took this dose on the way up. It’s almost like my body hates this particular sized dose. Still no additional weight loss though despite total appetite suppression (the likes of which I never had at 15mg).

I’m going to move down to 2.5mg for a few months or more and then attempt to stop.

I still struggle with people commenting on my looks so I now have a good few lines to deflect it.

…unless it’s people being rude and direct and telling me not to lose more weight, I just tell them I’m a perfectly healthy BMI and very happy (which is absolutely true).

I have to keep reminding myself that even though it’s been a two year journey for me it seems more of an overnight transformation to people that don’t see me often.

@MountKilimounjaro that is amazing! Well done. That’s an incredible loss. My weight loss is very low and slow that’s why I’m not posting as I feel I’m failing. I started officially 1st January or maybe a week earlier and to date I’ve lost 1 stone and 3lb which I feel I could easily have done without the mournjaro. I feel deflated! Any tips please?

@MountKilimounjaro fantastic loss, well done 😊

I’m aiming to do the same as you. I’m on 5mg and have been for a while but the goal is 2.5mg max. I’d like to come off permanently but I don’t think I can.

I’ve just been away for a week and my weight has gradually climbed each day. Ive put on about 3lb which isn’t bad, but I’d already put on 6lb so I’m almost 10st now which would be bmi25. I’m loath to go back up to 7.5mg as was saving that pen for doing 3.75mg.

good luck with reducing your dose and please keep us updated :)

@Georock January this year? In which case that is great progress. Most people on this thread have been on their journey for about two years and I think the majority of advice would be take it slow and steady, focus on nutrition and changing habits. My loss took a long time, at times I felt like nothing was changing and yet here I am now, an entirely different person.

@PissedOffNeighbour22as much as I’d like to stop entirely I think realistically it’s going to be for the very long term too. Hopefully at 2.5mg but let’s see!

I think finding where you’re happy and where your body wants to be is key. Your gain doesn’t sound huge at all and the fact you’re able to monitor and adjust habits where needed is great.

The hardest habit to get out of is thinking you need to always be losing.

@Georock Do you mean January 2026? That’s actually a pretty good loss. It took me 8 months to lose 22kg, which was about 1.5 lbs a week. If that’s your loss over 13 weeks, it’s not bad.
What dose are you on? If it is not providing sufficient appetite suppression to allow you to restrict calories enough to lose weight, then go up a dose.
MJ does not cause weight loss, it affects appetite.

@Moanranger @MountKilimounjaro

thank you both. Yes 2026 January.

This is really interesting. I’ve kept ordering 15mg pens although I’m at target, because I find I have very little suppression so didn’t want to drop the dosage (although I have a 5mg and a 7.5mg pen from the panic buying time). This makes me wonder if I could titrate down and still feel suppression.
For me it’s been neatly a year since hitting target. I went as low as 139lbs (at 5’9) but seem to have found an equilibrium at around 145lbs. Very much able to eat A LOT however these days and need to be careful to moderate my eating. Unfortunately some unrelated mobility issues mean that I’m unable to exercise so that doesn’t help.

@Femeiait really is the oddest thing, I was on 15mg for about a year so my body was very used to the dose and I could definitely eat a lot if I wasn’t careful so I was worried about titrating down.

I’ve just started digging into what’s happening and apparently it’s a re-sensitisation of receptors, as you drop down doses they become more sensitive again. It’s something called upregulation and not uncommon in hormone based drugs.

When I was on 15mg I was experiencing downregulation - my receptors were less sensitive as there was too much stimulation for a long time.

I still move injection sites regularly, mainly arms and stomach.

The suppression returning on lower doses is great, the side effects not so much. I really hadn’t missed the dreaded sulphur burps!

I know this thread isn't very active anymore, but its comforting to know it is here! We're all in the same boat, about 2 years in (I'm 2 years this month) and its incredible how far we've come. But I still have questions and sometimes want to check if something is normal, and only those who have had our experience can help me! We really were trailblazers! I'm taking 3.5mg and maintaining, have gained a lb from my goal especially over this easter weekend, I did overindulge easily but I do feel like the MJ stops me going totally crazy over food even on such a low dose.

Still here plodding along.

I’ve been taking 7.5 from a 15 pen for a couple of weeks. Somehow went for a week on all inclusive and stayed the exact same weight. Then since returning I’ve lost 3lb in less than a week.

Its all a mystery to me until take it.

I’d like to get down to 9 stone 6 again and see if I can maintain that without self sabotaging. So about 1 stone still to go.

That’s really interesting. Also the changing injection sites - I’ve always done stomach but maybe I should mix it up. I wouldn’t mind the sulphur burps again if it meant proper suppression!

I always check back on this thread to see the new posts. I’m glad we still pop up. It all seems so long ago we were posting constantly, losing, weekly weigh in.

Really interesting on suppression coming back on lower doses. I am taking 12.5, but I don’t count down to jab day now. It really ebbs and flows.

My new boobs are settling well. I almost wish I had gone bigger. 😂 They were done five months ago now. Time does fly.

I am still a gym nut who needs it for my mental health more than physical.

I have also had six months of therapy now. That has been very tough.

Still arguably tiny and I can now see it.

New clothes addiction tempered off.

It is lovely to see you all.

I’ve put on a few pounds and seem to be a lot heavier than most here. I’m around 11 st 10 but still wearing size 10 sometimes 12 at 5’11”. Someone on another site said I must be really dense 🙃

Less than 6 months now to my 360 fdl and arm lift flitting from nervousness to excitement! Titrated down to 5 mg every 8 days now back up to 10mg every 6 days. Think I’ll continue slowly going up and down for a few years yet.

Lovely to see familiar faces here again. Good for you @flappyfishkeeping up the gym, that’s a great thing to do. Wish I had that motivation!

@Scalessayeekthat’s impressive being a size 10! I’m 10 st 4, 5‘9 and very much a 12-14 still. It’s the boobs

Hello everyone, good to hear some updates.

I'm still plodding along, on 2.5mg or a bit less (i budget for 6 doses out of a pen so preparing for losing the 5th dose). Weight is not very stable; i bob around 9st 3 to 9st 6. I find i can gain really easily but equally shift it again in a day or two. As long as my size 10s still fit comfortably, I try not to worry.

My alcohol use has increased which is a shame as I was doing really well for many months but the MJ affect seems to have stopped completely - strange, as I still get reasonable affects on my appetite for food. Anyone else noticed the same?

I'm trying to be consistent with exercising every other day. I find i get really stiff and achey and some shoulder pain so definitely need rest days...my age i suppose.

Overall I'm pretty happy with myself but a bit bored with the whole thing now after 2 years - I'd like to drop the constant worry about weighing, measuring, gaining and losing but realise this is how things have to be for life. I also wish I'd carried on buying 5mg pens so I'd have more doses from my pen, and not sure if pharmacy would let me increase while bmi is below 20.

My weight has kept rising after my holiday and I’m now over 10st 😭. One more pound and I’ll have put on a stone in a year (next week is a year since my wedding when I was 9st 3).

It’s worrying that I’m still regularly taking the jab and it’s still such a big gain. So would I have put more on without it? Or am I wasting my money being on it at all? Still can’t decide.

@MountKilimounjaro I've just passed my 2 year mark. I'm 4 st down - I took it very slowly.
Can I ask....when you say you've gone down the doses, have you actually been buying the lower dose pens or have you used a higher dose pen for a longer period?
I'm taking 5mg every 5 days from a 15mg pen. My weight has been steady for a few months now and I think its time to try and reduce my dose.
At the moment, I can eat a lot although I'm trying to make good choices.
Its interesting to hear what you say about the higher suppression on the lower dose, and I'm wondering if its to do with the actual dosage or the pen. Does that make sense? I'm probably not explaining myself well!

Also, the skin on my face suddenly looks awful. My wrinkles are terrible!
Unfortunately, I've always loved the sun and probably have not been as good in my youth as I should have been with the sunscreen. However, it seems overnight, all elasticity has disappeared.
Anyone have any tips?

TIA

Hey all, nice to see everyone's updates. Good and bad. Slightly worried about the Wegovy feedback as I will be moving onto that soon.

I am on my last 15mg pen and decided the last month to just go for 15mg to try and lose what I have gained. I have actually started losing again and before easter got to 11st 3lbs. I believe after Xmas I was up to about 11st 10lbs. (From trying to reduce down to 10mg). So glad that I am able to lose. But also gutted that I only have 3 doses left of 15mg then I am switching to Wegovy. Only 1mg as that's what Zava would sell to me. My lowest weight was about 10st 4lbs.

I am hoping I can titrate up on Wegovy and start losing again. I assume that I will need to get to at least 2.4mg to start feeling much on it. Hoping I don't get bad side effects from it. I did start on wegovy back before MJ for one pen and mostly felt ok. So hope it's ok for me and I can lose.

Will see how it goes and will report back once I have started on wegovy! I am maid or honor for a wedding in August, so want to get down a bit to look nice in a dress. That extra Stone and half did really make a difference to how my body looks. Funny how that happens the lighter you are!

@Femeia can highly recommend changing injection sites, it increases bio availability. On the way up if a dose stopped having an impact I’d move injection sites before moving up, always gave me a few more weeks at higher suppression.

@Dontfearthe It’s been a mix of spreading lower doses across a higher dose pen, I’ve also used lower dose pens. So no, I don’t think it’s pen related but that’s a good question.

From my research it seems to be a well documented effect on hormone based medications. I’m pleasantly surprised. My 2.5mg this week (taken Sunday) is like when I first started.

Loving seeing so many familiar faces popping back up. I don’t think I’d have been as successful as I was without you all. It’s been such a valuable resource for sensible well balanced advice and ideas. I’m also very grateful that we recognise the psychological issues around weight that we’ve all been dealing with our entire lives. I shudder when I think about some online forums for weight loss injections.

@FlappyFish I'm supised you're up to 12.5mg. I remember you lost most of your weight on 2.5mg. Shame that 2.5mg doesn't continue to work well for you.

@MountKilimounjaro I’m going to try your suggestion. I have always injected in stomach but will switch to thigh next ime. I just need to shift that 2kg above goal. I have always been on 5 but suppression is weak. Fine for maintenance but not doing it for weight loss.
@Dontfearthe subcutaneous fat plumps out wrinkles & when you lose weight, this goes too. You could go the plastic surgery/fillers route. I am not. I just use lots of high quality skin products, moisturising masks, etc & wear scarves, high necks, etc. I got much more wrinkly, but I still prefer being a size 10. I also take Nutrition Geeks glow up collagen, but no idea if that is really working

Thanks @MountKilimounjaro and @Moanranger for replying.

I'm definitely going to try coming down the doses now. I dont really want to lose any more although would be happy with a lb here and there.
I've a few pens in reserve...from the dreaded price hike last year and having to continue ordering so as not to be cut off. Obviously the higher dosage pens are better value but perhaps its time to start ordering smaller pens.
I've eeked out my ordering to every 8 weeks and no one so far has had a problem with this. I just keep telling them that I had a couple of doses to go before ordering the last pen and this seems to answer their questions.

No, I'll not be getting fillers. I have however considered botox for the deeper 11s, forehead, crows feet and around the mouth. I would need an injector to been 100% honest as to whether its worth getting those done when I'll still be left with deflated wrinkly cheeks!
Honestly though, its a 1st world problem and I'm just happy to not be carrying that extra weight which was making me feel sick and depressed.

Happy anniversary for next week!

I do worry about the fact that even on the highest dose I’m not losing - albeit I am in maintenance so that’s intentional, but really I was hoping to maintain at a lower and cheaper dose. And I am concerned about not being able to come off it at all, with the added cost and the uncertainty over being on it for a long time.

I am pretty pissed off with oushk. Because I completely needed the wegovy out of my system, they are forcing me to 2.5 mj. They ar saying there is too long since I've been on mj... But that's because I took wgvy 🤦🏽‍♀️

Is it swift Dr who people use here? Can't remember the name of the the other pharmacy who does decent maintenance.

I haven't weighed in over a month. But I know I am definitely eating more.

Pharmulous are also GP led, so can take a more tailored approach like SwiftDr.

I also tried Nulife recently who are "maintenance specialists". They were great and want to develop a relationship to support you. Prices were great and I could choose a delivery date too.