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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro 10st or more to lose - Thread 5

999 replies

TheBroonOneAndTheWhiteOne · 30/06/2025 12:41

Come and join us!

OP posts:
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38
FatsiaJaponicaInTheGarden · 28/07/2025 15:01

I'm not sure about bmi - I vaguely remember there were some categories I'll see if I can find.

But mean starting rate was 106.7kg so lower than I am after 6months....

So yes there's definitely an element that most people will have got to a healthy weight which will definitely affect why it levels out.

I think with the chart we could read it that higher doses "did more" on average. But that doesn't necessarily correlate with a need to get there quickly. What they didn't do was respond to individuals weight losses as they had allocated people to the groups so that's the dose they got. I'm still wanting to stay on a dose while it works so I've still got doses to go up to but again it depends what we mean by "it works". Some people won't be happy with a pound a week others will.

And yes Silences point is good and helped me v early on. They are dealing in averages. 20% of 13 stone would get you under 11 stone. Someone 13 stone wouldn't have 50% to lose like I do!

Id love to know more about the individual journeys but they've not released that. (Probably won't as it wouldn't be anonymised then?)

When I went down a Reddit rabbit hole there are all the options and experiences - people for whom they feel they wish they'd gone slower as they have "nowhere to go" as well as those who would have gone up faster. Or those who went fast and lost lots or those who micro dosed and managed to lose consistently on sub 5mg doses.

I think we just don't yet know - which is also why these type of threads are useful to hear what other people are doing. Especially as doing this for over a year is very different to knowing you can get to goal in 6months.

SecretSquirrel703 · 28/07/2025 15:53

@Iwouldratherbesinging skin tags can be associated with insulin resistance, so reduction highly likely to be MJ linked.

justteanbiscuits · 28/07/2025 17:14

I wish I had gone slower. When I was losing OK (1.5lb - 2lb a week) on a dose, I wish I'd been able to stick with it longer. But as my prescriptions are consultant led, he wanted me to get to 15mg if I didn't have side effects. I do find the effect wears off, and I don't want to go any higher (consultant is willing to prescribe up to 20mg, but that's because I am using it 'off label' and weight loss is a very desirable side effect!). BUT, saying that, as I've not been prescribed it for weight loss, and it has massively helped the symptoms of my adrenal tumours (benign) that it's been prescribed for, I shouldn't complain. I've gone from having adrenal / cortisol crashes multiple times a week to maybe once a month.

Wibbs · 28/07/2025 17:24

I have spent the last few days reading through this thread and want to thank posters for providing both inspiration and knowledge. Particular thanks to whoever recommended Meredith’s exercise for seniors on YouTube - not that I have actually attempted one yet, but they look exactly what I need ☺️.

Early days for me - third injection due on Wednesday and I am undecided whether to stick to 2.5mg or up the dose to 3.75 or 5mg next. I definitely will be using the golden doses though. I have been dieting on and mostly off for 4 decades. I have been able to lose weight in all sorts of ways from healthy eating and exercise to VLCDS. I do well, but have never been able to keep it up for more than 6 months with the weight I have lost (plus more) piling back on. So far I am very encouraged, it has never been so easy to keep well below 1,500 calories - I am tracking what I eat but haven’t placed any restrictions thus far.

I don’t have a goal weight as my primary aim is to increase mobility and general health. I may change my mind, but I think I would be happy just with a BMI below 35, but that decision is year or more off unfortunately.

TragicMuse · 28/07/2025 18:17

Hello losers! Welcome to new loser-friends!

I’m back from Latitude. It went well, walked loads because our working spot and camping were both uphill from the main arena areas.

I discovered the joy of the child’s portion size from the food vendors that I visited, which was revelatory! We also cooked in camp which was good for portion control. I’ll be back to my daily weigh tomorrow to see the impact.

It was great but knackering!

Iwouldratherbesinging · 28/07/2025 18:22

Thanks @SecretSquirrel703, I didn’t know that!

MontysMissus · 28/07/2025 18:27

Evening all! Day 5 for me and had my first supermarket shopping trip. It was a really weird experience.
I was looking for something to eat tonight and NOTHING appealed to or excited me. A couple of items would fleetingly grab my attention , and then poof, the feeling was gone. My normal shopping experience involves buying all kinds of shit and talking myself OUT of putting stuff in my trolley, not the other way round. If this is the future, then I'm all in!
DH is worried that I'm now not eating enough, so I need to find a balance.
Loving all the success stories, hints, info and tips. Keep it coming, and good luck!

Iwouldratherbesinging · 28/07/2025 18:32

Nice to see you back @justteanbiscuits and 6 stone 8 down too! I’m also enjoying clothes, I’m having to reign it in a bit though, I buy stuff (all Vinted though) wear it a few times then it’s too big again 😁, I need just a few things not loads!

@FatsiaJaponicaInTheGarden climbing up a lighthouse is pretty impressive! I keep going down Reddit rabbit holes, I can’t help myself…

hello @Wibbs, your story is very familiar and I’m sure that we can all relate 😊

welcome ‘home’ @TragicMuse sounds like you had a wonderful time, hope the rain didn’t affect you too much!

TheZingyFish · 28/07/2025 18:59

Week 16
SW 24st 9lbs
CW 21st 7lbs
Total lost 3st 2lbs

Has been a strange week, for the first time I started to wonder that the effects were wearing off and started to panic as I’d just taken delivery of my third 5mg pen so worried I should have ordered the 7.5mg. I’ve found I’ve been picking a little bit although still massively under my calorie allowance.

That said I bought a pair of size 24 trousers from Next and they fit! I started this journey wearing size 28 jeans, but can now wear a 24 comfortably. I’m so close to being able to shop on the high street, am dying to go to M&S and see if I can get into their size 24s now. My top half isn’t shrinking in the same way, still in size 26/28 but my shape has improved. I do have a large bust so will need to ensure I keep updating bras, no shortcuts with a K cup unfortunately, but not quite there yet!

I feel reassured so if I do need to move up a dose I will just roll with it this month, and go with the flow. I know this works so I’m happy to go a bit slower this month if need be. In some ways it will do me good to have to use a little more will power as that will be the reality the future.

OvertiredandConfused · 28/07/2025 20:08

Unbelievably, I’ve lost 1lb this week, despite being on holiday!

I’ve learned that, as long as I drink lots of water and make a few sensible choices, the medication really does do its job! I’ve had tasting menus, cocktails, wine and every time I’ve eaten much less than I usually would. A couple of times I’ve wished I could eat more, but it hasn’t been a struggle so far.

Six days to go and even if I gain a bit, I know it’ll be manageable

TragicMuse · 28/07/2025 20:38

OH, I completely forgot to add this earlier!

Our usual routine is to set up our workshop and then our crew go and hit the festival Oxfam shop. I have never been able to buy anything in the years I’ve gone because they never have my size. One of my hopes was that I might be able to participate and enjoy looking at the shop rather than having to look happy only looking at sunglasses or bags.

LOSERS! I did! I bought a tunic/short dress. It’s River Island. It has a ruched elastic back panel. It fits. IT’S A SIZE 16!!!!!

Meanwhile, the jeans I bought a few weeks ago are already loose.

IT’S MAGIC AND I AM HERE FOR IT!!

TheBeesTrees · 28/07/2025 20:56

Everyone is doing really well!

I didn't need the peptobismol for the sulphur burps in the end, I took a tablet for wind that I already had and it seemed to ease off, but good to know for future occurrences (altho I hope they don't happen!).
I have minimal appetite on 5mg so far although it's only day 3 so we'll see how the week goes.

afaloren · 28/07/2025 21:28

Great losses and NSVs everyone!

My NSV from recent days is that I went on a march and was able to keep going for the whole two hours. My back hurt a bit by the end but at my biggest I could barely walk for twenty minutes. Feels great to be able to participate in things that are important to me.

I also went through my wardrobe and donated three big bags of too-big clothes to charity. Discovered other things that fit properly but were previously too small so now when I go in my wardrobe I’m not overwhelmed by stuff that doesn’t fit. Feels good!

Doggymummar · 28/07/2025 21:38

Some lovely stories here. Weird NSV for me. I bought some Levis for my other half 513s 32 32 and they were too big for him tried them on and they fit me perfect, well about three inches long so I am keeping them. £2 on WHATNOT bargaliscious

Bulldogsummer · 29/07/2025 06:31

Iwouldratherbesinging · 22/07/2025 22:24

I know we all say at the beginning of this journey how far we have to go, and yes, in the early days it’s so daunting and can be overwhelming when thinking about how long it will take, but I can honestly say that once you get halfway, or even before you reach that point, it really doesn’t feel so far out of reach, all the nsvs along the way are like mini victories and such morale boosters.
This isn’t the same as the misery of a restricted diet where you are constantly thinking about your next meal and what you can or can’t have. I’m the happiest I’ve been for a long time, I don’t really care about how long this will take anymore, I know that I will get there and then I’ll be worrying about maintaining/gaining and I don’t want to think about that for a while as I’m happy in my ‘little’ weight loss bubble.

Absolutely this
I can cross my legs now ,like actually sit in a chair and comfortably cross my legs ,it's unreal ..
Over 7 and a half stone off ,I tract my calories and I eat anything I fancy ,I just work it in ..
I'm so near to the weight I was getting married,I can't believe it
Better than any antidepressant for me

eibbed999 · 29/07/2025 10:43

MontysMissus · 28/07/2025 18:27

Evening all! Day 5 for me and had my first supermarket shopping trip. It was a really weird experience.
I was looking for something to eat tonight and NOTHING appealed to or excited me. A couple of items would fleetingly grab my attention , and then poof, the feeling was gone. My normal shopping experience involves buying all kinds of shit and talking myself OUT of putting stuff in my trolley, not the other way round. If this is the future, then I'm all in!
DH is worried that I'm now not eating enough, so I need to find a balance.
Loving all the success stories, hints, info and tips. Keep it coming, and good luck!

I was exactly the same in the first week, @MontysMissus, struggled to find anything I fancied! It was quite liberating but also I knew I wasn't eating enough, so had to employ some will power to make myself eat some nutrition rich foods to keep the calories up. Very strange feeling as the whole of my life it's been the other way around! For most people it does settle down and you find a balance as your body and mind adjust.

Rahgh · 29/07/2025 10:46

Hello, please can I join you all? I love your positivity and support for one another. I’ll join the monthly threads but I think I could really do with some support from people on a longer journey. I have just ordered my first dose from Numan am planning to start mounjaro on Friday or Saturday (our darling dog has to have his teeth cleaned under sedation on Friday and if he has teeth removed I want to be fit to nurse him!).
I have been reading as much as I can on here for weeks to be as prepared as possible. I have over 10 stone to lose - in theory - so I need to go steady. I remember being 13 stone when I was 13 and I can’t even imagine being less than that! Currently almost 21st. I echo a lot of your comments about having years and years of records from failed attempts to lose my weight. I’m so desperate to be able to tolerate the side effects and finally get myself healthy before I turn 50 - 2 years away!

You’re all giving me so much hope that things can change. My husband knows and I will tell my teenage children but scared to tell friends.

Any tips you have please let me know! What would you tell someone starting out? So far I have noted:

  • Clean eating 48 hrs prior
  • Take probiotics
  • Expect SE worst for first 48 hrs
  • Have Rennie, pepto bismol and anti nausea meds on stand by
  • Drink lots of water
  • High protein snacks through the nausea, I’d like to avoid shakes etc as processed foods can give me migraines.
  • Try to keep calories high (worked out TDEE) so i can reduce as get nearer target - chat GPT recommends 1800 so I’ll need to eat what other people will consider a very “normal” amount.
  • Ginger chews/ biscuits and mint tea for sulphur burps.

I’m so scared it won’t work or tolerate the side effects but I’m of the opinion if I don’t try, I won’t know! I am scared of side effects as I can be a bit IBSy at the best of times.

eibbed999 · 29/07/2025 10:59

Morning all - loving your stories! Especially yours @TragicMuse, you always sound so enthusiastic! I think it's week 18 for me, but I've moved my jab day around a few times for various reasons so I've lost track a bit.

Feeling a bit bleeeugh at the moment, a bit weedy and shaky. I'm definitely eating enough, drinking water etc, and haven't changed dose, so I think maybe I'm about to come down with something. Off to dog sit down South tomorrow - so hoping it goes away!

Was feeling so squiffy yesterday I think I might have sent the wrong parcel to a Vinted buyer, switched two up, but I won't know until they get there. I got so stressed by this, and had to give myself a good talking to - what's the worst that can happen, a bad review on Vinted?? That's not the end of the world but for some reason my mind was trying to convince me it was! Silly mind. On the Vinted front though, I bought a Nobody's Child dress in an 18 (and they fit small) and it fits! A little snug on the boobs but it fits. So then I was elated and flounced around the house feeling like a foxy nymph, until I stood still, looked in the mirror, and thought: 'Yuck, you're still enormous!' These rollercoaster rides are such fun!

Anyway, weigh in/jab day and all is well. I hit exactly 18 stone today, which means next week (all being well, we are away!) I will both head into the 17s, and hit my 4 stone loss.

SW: 307lbs
CW: 252lbs
GW: ??

eibbed999 · 29/07/2025 11:07

Welcome @Rahgh, sounds like you've done your research! Mainly I'd say keep an open mind, and always be aware of how differently the drug seems to affect people. Nobody's journeys are the same. Also, try not to be too hyper focused on side effects - the more you search for them the more likely you are to find them! Give everything a chance to settle down. Good luck and looking forward to hearing how you get on.

Elle771 · 29/07/2025 11:13

Love all the NSVs and buzzing for your oxfam joy @tragicmuse 😊

Have just ordered my 3rd 5mg pen but wishing I had ordered 7.5 as feel the momentum slowing a little BUT as everyone says on here will just keep going and trust the process!

Starting to think about low level exercise now... more to help mentally but also might help firm up a little as I hopefully continue shrinking!

How do people tend to manage mini plateaus/bleurgh times when we are all in it for the long haul?

MontysMissus · 29/07/2025 11:17

Had an email saying my GP referral to the Tier 3 weight loss programme has been successful and I've been registered with Oviva. Has anyone else got experience with them? Apparently there's a 15 week wait for a consultation but I'm happy with that and reckon tge further down the line I've got on my own steam, the more likely they'll accept me. Fingers crossed.

MummyInTheNecropolis · 29/07/2025 11:34

I’m just back from my holiday in Majorca, had a fabulous time, easiest journey ever as I fit perfectly in the plane seat, even had to tighten the seatbelt! Felt confident in swimwear for once and actually wore a bikini for the first time ever! I ate and drank whatever I wanted (which was much less than usual!) and just stopped when I’d had enough - so unusual for me! Really savoured and enjoyed the food and cocktails but found it liberating not to be constantly thinking about what to eat and drink next. Did lots of walking and swimming so I’m hoping I haven’t done too much damage. Have decided not to weigh myself until Thursday which is my official weigh in day. Even if I’ve gained a few pounds, I won’t care, it was well worth it and I know I’ll lose them again easily.

PositiveAttitude · 29/07/2025 11:35

Hello everyone.

Welcome to the newbies here.

Some lovely NSV for lots of you. I can't wait until I can cross my legs again. It makes me feel so much more ladylike!!

Well, I have had a bit of a week. I had my first 5mg on Wednesday evening. Thursday I was fine, then Friday at work I nearly collapsed. I was hot and cold at the same time, not seeing straight and was all over the place. I got home and spent the next 48 hours in bed. I thought it was a bad reaction to increasing the dose, so I confessed to DH about it (had been a secret jabber), he hit the roof, told me to stop it immediately, it wasn't worth it if I was going to be so ill, blah blah blah..... Anyway, our eldest daughter then was struck down with the same symptoms as me.... We obviously had a virus!!! 🤦🏻🤦🏻🤦🏻 It wasn't SE at all. I felt so stupid for jumping to conclusions!! DH is now on board with it and supportive.

I also got mixed up with my weight and got quite negative, thinking I had hardly lost any weight over the past week. But blame me being poorly for my lack of maths, because I have a loss of 6 lb showing on the scales this morning.
So I am now feeling far better about it all. It does feel so very overwhelming to see how much I have to lose, but I didn't put it all on over a few weeks, so I know it's going to take a few years to get where I want to be.

To the Dr for a BP check later today after it being a bit high the last few times it has been taken. I am hoping that it has already improved.

Bulldogsummer · 29/07/2025 12:39

Another NSV
Last night I cut my toenails,I just sat on the bed ,bent down and cut them
Usually I have to get in to all sorts of positions to cut them ,and I've never painted them because I could never reach .
I'm going to buy some polish and paint them .
What I'd really love is to go for a foot manicure..I've never had one ,
Maybe one day

TragicMuse · 29/07/2025 12:45

Sneaky post-jaunt WI, pretty much a STS so far and I’m totes good with that.

I’m taking my scales on holiday - we’re going to my mum’s so it’s not that weird!

I haven’t told my mum anything about it but I think it’s going to be noticeable. A few years ago I implemented a total ban on discussions about my body - after decades of weight-scrutiny - and after a few false starts she’s been able to not say anything. I don’t know if that will hold as it’s starting to be visible that I’ve lost a fair bit now - my festival crew friends all noticed!

AND I’ll have the jabs in her fridge!

So I guess we’re probably going to have to have the conversation, and then hopefully let it go.

Eh. Let’s see how it goes!!