Mounjaro 10st or more to lose - Thread 5

[TheBroonOneAndTheWhiteOne]

Come and join us!

Thanks @SilenceInside the 10ml pen is exactly the same price as the 7.5ml so price isn’t factored into my decision. I’ve got 2 more doses in the current pen (including the 5th dose) and it’s so difficult to know how I’m going to be feeling in 3 weeks time!

It’s tricky, but the 10mg pen would give you the option of either dose, and you would be able to get a 5th dose of 7.5mg out using the pen if you used it for 4 x 45 clicks.

I was stable on 7.5mg for such a long time that it took me a while to figure out it was time to move up. With the benefit of hindsight, I think I would have moved up a month earlier. But I didn’t think that at the time, if you see what I mean.

Yeah, I've been on since March 23 and went up every 4 weeks,no even using the fifth dose. Guidance seems to have changed more recently

Hello all
I had my first jab of MJ 2.5 yesterday (I had a headache before I jabbed so maybe should have waited but I wanted to get going.) I had a headache all day and the thirst is unreal but no other side effects so far.

I have well more than ten stone to lose and have never managed more than five on any diet (which I've done a few times but then always put loss and a bit more back on when I fall off the wagon) so hoping the suppression affect might be the thing that helps me this time.

Tracking calories on my fitness pal to make sure I don't go too low (another thing I've done previously i know)

I did the same apart from 2pens at 10 but which I had gone to 12.5 sooner

3rd dose taken, fingers crossed for less side effects than last week!

I did as well.
I feel like I've been on 15mg for a hundred years.
🤣

That’s a lovely boost of confidence @Motnight what cheeky buggers!

@PearlsPearl that was lovely to read ☺️

@Lozzie118 only my family know, if I’m asked how I’m losing weight I say I’m 5:2 fasting (which I am). There’s too much negativity out there for me to just come out with it.

I did the same, I was always advised to move up through the doses as quickly as you can tolerate too as you are aiming to get to 15mg as an optimal dose so this is what I did (apart from two lots of 7.5mg which I instantly regretted). In the trials people were consistently losing for the 72 weeks on 15mg. Obviously advice seems to have changed (but it’s hard sometimes to weed out the real advice from the made up stuff), but cost also plays a big part for many.

Does anyone think it affects their mood, mine has been a bit all over the place today up then down then up again and now back down x

I don’t think the advice has explicitly changed, but I think it’s just been made clearer that the dosing schedule is the suggested schedule and can be varied due to individual response. In the trials some people could only tolerate the 5mg dose, some the 10mg and others could manage the 15mg. So not everyone went up to the maximum dose and stayed there for the duration of the trial.

I'm the same, but dont know if the mounjaro is contributing or not. My friend died last month, we knew it would come eventually (stage 4 cancer) but was still quite unexpected. That, last six months of a PhD, clearly menopausal, hitting 50 later this year. Think it's all making me miserable! Am wondering if my iron is low too as its historically been low and needed iron infusions and it's not been checked for 3 years.

On doses, my friend started in October and has stayed on 2.5mg and lost over 4 1/2 stone. She wanted to still feel a bit hungry and need to use willpower. I kind of wish I'd done the same now.

Tho she may have not coped with high doses and 15

2.5/5 did nothing for me

tbh 15 still didn’t stop the urge for crisps chocolate pizza takeaways etc

I never had the oh j can’t eat /face that that so many talk about

equally I’ve never had any side effects or losing hair that so many mention

I would have to limit my self to having one

I'm still here. Lurking. And think I may be over my barely losing phase, having lost a Kg this week 😁 I went away two weeks ago, and the meals were shocking carb heavy, so I stuck to veg and protein, no carbs with breakfast and I did OK. I was very busy so didn't have time to think about snacking!

It was the first time I've been away and not carried two changes of clothes in hand luggage though. I was always paranoid about my luggage going missing and not being able to buy clothes that would fit in any shops. This time I knew I would be able to go to a Primark type place and find clothes!!

So 6st 8lb down. I was hoping to be nearly 8stone down by this point earlier in the year, but I'm feeling positive again!

Size 18 clothes are starting to be loose. I have started wearing more fitted t-shirts and culotte type trousers and loving it. I had just bought my first pair of size 26 jeans when I started this. I'm enjoying clothes again.

I’ve ordered the 10!

Just after ordering I literally had to run to the loo (and nearly didn’t get there in time 😳) faster than I’ve ever moved in my life and whoosh 💩. Typical I thought, now I get side effects on the 7.5m, then I remembered the sugar free sucky sweets I had been munching on in the car an hour or so previously……

If anyone is after cheap, effective (and nice tasting) laxatives, I recommend the ones by the tills in Lidl 🫣

Really enjoying the discussions and support. Only on Day 5 of my first set of 2.5mg so the jury is still out, but no adverse side effects so far. Toying with whether to stick with 2.5mg next month or move up. I'll weigh in on week 3 and decide then.
One thing I am doing is peeing for England , so I'm hoping, at least, for a water weight loss!
One thing I was wondering about the hormones that these drugs emulate... do folks like us, the not naturally slim folks and those who struggle with "self control" etc, actually lack or have less of those hormones prevalent in our systems naturally? It's not like we're ever tested for their levels... I've always envied folks who can, without thinking, it seems, stop eating when full and leave food on their plate. What have they got that I haven't?
Just a thought...

NSV - I managed to take my wedding ring off! It has been trapped on my finger for well over a decade. In fact I was worried that at some point I was going to need to get it cut off.

Morning.

I've been away for the weekend (coming back tongiht!) and just read up on the thread. Hello to lovely new people 😊.

Im curious about the dosing. Most things I've been reading recently have been around staying on "lowest effective dose". I'm around 6 months in and on 7.5. My average is around a kg a week but it's slowing a bit (but still over a pound a week on average) so it's worked so far as its still a good loss so I've not lost out by not going up fast. I will need to decide in 2 weeks though whether to go up and was internally wondering at what point of weight loss slowing I'd do it! I'm tempted to go up this time.

As someone who knew I'd be on it a long time spacing it out (as long as it was working) made sense to me but I'm interested that lots of those further ahead than me went up "quickly" and it's still working/worked for them so there's obviously more than one way to do it.

The trials were set at 5mg/10mg/15mg and as it was a trial for each dose the participants had to get to that dose ASAP foe them to get the data they needed and we see their average weight loss stops at about 72/85 weeks.

They haven't properly studied different patterns of dosing. I'm hoping that by following "lowest effective dose" I'll be able to keep the weight loss going for longer. But I don't think there's a clear protocol currently (other than at least a month at each dose from Eli Lily).

In other news I've been away and I've managed at least 10k steps each day and really truly enjoyed being able to "just walk" and move my body. I'm so grateful to MJ. Much of that's the weight loss but as it happened early on it must be the anti inflammatory effect and I do wonder if I'll still need that when I've lost weighf.

And get this - I went UP a lighthouse!! I wouldn't have dreamed of doing this a year ago as I'd have been aware I'd need to stop on steps or be scared of needing to come down. I even went up theast ladder bit! My kids were celebrating with me after.

They've taken some photos and I do still look very round. I do carry much of my weight in the middle so I look very fat still which was a bit disappointing. The photos don't reflect how I feel unfortunately. But the fact I feel good and can walk has been amazing. When I planned this trip I'd been researching car parks and places we wanted to visit to check I could "manage" the walk from the car park etc. Its shocking to see the photo of an obviously very large person when I feel so much slimmer and more able inside!

But the main thing here is that I can do more. And have eaten differently to usual but mostly not ocerinduged. Our meal out yesterday I had soup as just was not hungry. The breakfast on the other hand I definitely had an egg and hash brown as well as the yoghurt and fruit. It was a really good breakfast! But I guess in times gone by I'd have eaten even more....

Hope everyone's okay. I will have to have a ponder over the next couple of weeks about my next dose!

@MontysMissus

I do think there may be a deficiency or lack of response to certain hormones in people who are very overweight. Not all which is why mounjaro doesn't work for everyone.

I'm on mounjara because I am T2 diabetic. I am noticing a massive change in the food I am wanting to eat. Previously I was a real bread monster. Now I no longer want to eat large amounts of bread or pasta.

We had a takeaway for dinner yesterday, shish kebab for me. I only wanted the bits if the pitta which had meat juices soaked in, less than 10% of it. In previous times I would have eaten all of it without thinking.

@FatsiaJaponicaInTheGarden I'm another middle weight carrier. I can tell weight has come off arms and legs but the middle barrel shape remains!

Yes there must be something going on mustn't there. I'm similar in that I don't crave the carby food I used to (although I'm not diabetic). It feels so much easier to eat as I used to want to - real foods, moderation, stop when full type approach.

And yes to people being at their goal already. I've not gone back to my starting month thread as I wasn't good with all that although I know that's my issues.

I lurk on a Facebook group for my provider where we mostly started in January and I'm dipping into that less as so many people are at maintenance or close..

I think as mounjaro has taken off a lot of people are now using it for a few stone which is a compeltley different game to us.

I also wonder about those who plan to just use it for a few months and come off how that will work or if it will as they don't have the issues we have in the first place.

I occasionally read the threads where people either want to or admit to using it when not eligible and that makes my brain spin.

@FatsiaJaponicaInTheGarden well done on the lighthouse! I feel really pleased for you about that. I'd not have the courage yet to do something like that.

I've never seen that chart before. Now it's making me think I should go up the doses, it's clear there is much more weight loss on the higher doses. I'm on week 10 of 2.5 and losing consistently so figured there was no rush to go up, but now I'm wondering if I should. I have a 5mg pen in the fridge, I wasn't sure if I was going to use it or get another 2.5mg pen first.

Also I hate the regain figure. 17% 😣I can't bear the thought of regain. I want this to be life changing for good. I guess there's no data yet on people who just stay on it indefinitely. Which I'd be more than happy to do.

The thing about those charts is that they are averaged across a large number of people. I’ve already lost 40-odd % of my starting weight, and still going, and I’ve only recently moved onto 10mg. I’m at 55 weeks on Mounjaro, I think.

I also wonder how many in the trials had the kinds of BMIs that most of us here have started with, high 40s and 50s. I think the average starting BMI was somewhere in the 30s, which I’ll see if I can check. A lot of people will have stopped losing weight because they had reached a healthy weight range and probably were not actively trying to lose any more weight.

I definitely found that on ozempic, I thought I was going mad at one point! Peri menopause, a full time masters and children with multiple issues had an effect as well, but once I went up to the next dose it eased off again so deff think it was connected!

Re regain - I also like to think that as we have lost a large amount of weight (or will have) over a longer period of time, we are more likely to have a better chance of maintaining that loss in comparison to someone who has lost a couple of stone in a much shorter period of time. I know that I can maintain weight by 5:2 fasting, I just can’t lose it by fasting alone. That’s the main reason for continuing the fasting ‘habit’ so it doesn’t feel like I’m depriving myself when I get to the point where I need to maintain.

Another thing I’ve noticed recently - skin tags, I have them around my neck and would always wear my hair down to hide them, but they’ve shrunk! They are barely noticeable now - more wizardry??