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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro April 2025 Starters

1000 replies

OpheliaABC · 26/03/2025 19:28

Anyone else starting soon/in April? I've seen there has been lots of threads for new starters for the previous months which looked helpful so I'm starting one too.

Starting weight: 98kg
Goal weight: 75kg

I will be starting either at the end of this week or early next.

I have a huge appetite, lots of cravings for junk food, and I'm hoping to get my portion sizes under control. Three members in my immediate family have now been diagnosed with diabetes and I'd rather not join them.

I'm having full blood work done in a few days to make sure I don't have deficiencies, thyroid problems or overly high blood glucose levels. Trying to give myself a full health MOT but I love my food so it won't be an easy ride. I can only hope this works for me and that my portion sizes will be halved without going hungry as I've seen happen to some people.

Welcome, if you are joining me! 😊

OP posts:
Thread gallery
11
QS90 · 04/04/2025 01:05

JMSA · 04/04/2025 00:49

How are everyone’s energy levels?
Mine are fine during the day at work, as work is obviously something that I HAVE to do. But home is a different story Sad I am absolutely exhausted. I come home and can’t stop myself from having a massive nap. Then I’m awake and going to bed at crazy o’clock. I’ve barely seen my teens in days Sad
It feels like I’m in a really bad cycle. My washing pile is insane because I just haven’t had the energy to tackle it. I’m not sure how normal this is, but I’m guessing it’s not!

I am quite tired in the day, it has to be said. Need pints of coffee to get through the day, then up at night 🙄I've always been a bit like it, but definitely worse this week.

Hopefully our energy levels will be better when we've lost a bit of weight and are healthier. I feel like that's something that's supposed to happen...

JMSA · 04/04/2025 02:59

Thanks for replies re energy levels. Prior to starting Mounjaro this week, I was on a very low calorie diet. My energy levels were through the roof, so I hadn’t really expected this to change. Ah well, it’s just an adjustment, I suppose.

JMSA · 04/04/2025 06:30

Oh, and I’ve also had a tight chest since last night. Having googled it, this can be a side effect of Mounjaro.
Unless things improve, I’ll be returning to my very low calorie diet. I may have felt real hunger at points, but my energy levels were high and I generally felt fantastic.

Doidontimmm · 04/04/2025 07:05

Morning,

2nd jab day!

SW 11st 11lbs
CW 11st 7lbs

4lbs off - happy with that :)

PearlFatball · 04/04/2025 07:09

Second jab day here as well.

Also 4 lbs down. Not sure how much is just water weight as on my period but will take it for now. Probably best measured on a monthly basis in any case even menstrual cycle fluctuations.

wordywitch · 04/04/2025 08:22

I’m 24 hours post injection and don’t feel any difference really. I had my usual level of hunger when I woke up this morning and had scrambled eggs with veggies for breakfast. Will be interesting to see if I get hungry again before lunch or not.

Raffles134 · 04/04/2025 08:27

I’ve done it! 1st injection this morning and I did it myself as I needed to know I could do it.
And guess what….i didn’t even feel it 🤣
Have been stressing about it so much and yesterday I thought I’d leave it til Monday so I could have the weekend to eat & drink what I liked but woke up this morning and just wanted to get started.
I ate absolute rubbish yesterday and didn’t want another day of bad eating. I won’t risk eating like that today now for fear of side effects!

Starting weight 98.43 kg

So glad to have found this group for reassurance.
Thank you!

Raffles134 · 04/04/2025 08:41

OpheliaABC · 03/04/2025 13:25

I just had a look at this thread. I think I will try to get a fifth dose out with an extra syringe and take it, if there's enough left.

www.mumsnet.com/talk/weight-loss-injections/5258100-the-extra-dose-of-mounjaro?page=1

I will still order my next pen as normal. It will stay safe in the fridge unopened until I need it on week 6 (or week 5 if I don't manage to extract the "bonus dose" from the previous pen). :)

Thanks, have been reading about extracting the 5th dose. Think I will try this too! Have you ordered the 8mm syringes that were recommended?

TimeToGetThin · 04/04/2025 08:52

I’m nearly 36 hours past 1st injection and not feeling hungry at all despite my last meal being 11 hours ago.

I’m still struggling with the head hunger - feel like I should be eating something. I think if I can stay on these jabs long enough (at least 1-2 years) it could recalibrate my emotional relationship with food.

I feel my usual level of exhaustion (2 small kids!) and last night had cramping in my upper abdomen and this morning have some chest tightness.

I’m also 1&1/4 lb down but I tend to fluctuate 4lbs anyway over the span of a day.

Mounraine · 04/04/2025 08:58

First jab last night and I too felt tightness in my chest most of the night. Kept telling myself it was yesterday's yoga class.

I normally eat two meals a day, but am going to do three small meals on 16:8 where I can, instead.

ValliBec · 04/04/2025 09:25

Morning,
I took my first dose yesterday late afternoon and I had chest tightness over night too - reassuring to hear others experienced the same thing (although sorry you’ve had it too!) I have asthma so I wasn’t sure whether it was just coincidental but thinking it was a side effect now.
I also had a slight headache and felt really cold overnight, to the point I had to put socks on in bed but by morning I started to feel really warm!? Wasn’t sure how long side effects take to kick in - I think the headache may have been from stressing myself out before actually doing it 😀
haven’t eaten anything this morning yet but that’s not unusual for me, I’m not normally hungry when I wake up.
Hope everyone else is doing ok 👌🏻

GreenSalon2 · 04/04/2025 09:46

Morning, having read these threads for months while trying other ways of losing weight, I’ve taken the plunge as I managed a total 6lb weight loss in 3 months. First dose this morning via Superdrug. I tried ordering with Lloyds but got fed up with their upload system so asked for a refund.

CW: 90.2kg
TW: 70kg though would be happy with 76kg.

70kg is still slightly overweight for me height wise but I think it’s a more achievable goal thinking of future sustainability if I get there.

I’m 54 and have been 90kg since going through early ish menopause 12 years ago and my metabolism slowing right down with age. I take HRT and would not be without it but have been in denial about my weight until a year ago when I realised if I don’t tackle it now, it’s not going to happen. I’ve been weightlifting and working with a pt since last year to build up good habits first. I’ve gone from being entirely sedentary to non negotiable workouts 3 times a week and a minimum daily step count of 10,000. But I NEED to get this weight shifted now and hopefully get to something sustainable.

TC4 · 04/04/2025 09:48

So week one done. I’ve chosen to do daily weighs at the moment, today I’m 5lb or 2.4kg down from my starting weight, with daily weighs the biggest I’ve seen is 6lb down but obviously there will be fluctuations. I didn’t suffer side effects except slightly cold, a very slight headache one morning and a sudden need to 💩 after a Mother’s Day chocolate waffle 😂😂. My hunger has returned a bit since yesterday and I did make a couple of bad decisions yesterday but today I was hungry and had one piece of toast with a banana. Il do my next injection this evening once my little girl is in bed.

im not sure if some of what I’ve noticed is psychological but either way its positive as I’ve been finding getting up and down off the floor with my daughter a bit easier and I’ve had energy to go on long walk/jog/runs with her on her scooter I have actually done well over 10000 steps on the majority of days this week which is unusual for me. So im happy with that and my sister has convinced me to join a boot camp exercise group which starts next week so all positive - let’s see what the next week brings

Lundier · 04/04/2025 10:09

What concerns me, and the reason I haven't done this before, is that I'm not especially anxious about my body. I've got fat from eating and drinking too much, in my merry life, not from sadness.

I don't weigh myself or look in the mirror or take pictures or any of the other anxious stuff my friends who have bigger body issues do. I don't want to adopt these practices because I can see how unhappy they make my lovely friends. But the programme already seems to invite a lot of weighing and thinking about my body as some kind of separate thing to myself. I've always just felt like I am my body and I don't want to disassociate in this way. :/

I think I might be giving myself a complex that I didn't need. It's put me at level 1 on movement, which surprised me as I don't have a car and I live on a big hill so I walk everywhere, and climb a lot of hills. Have I lost touch with what is normal? Are most people walking 10k a day?

HesDeadBenYouCanStopNow · 04/04/2025 10:20

@GreenSalon2 it sounds like you're my weight loss twin.

I'm also 54

I started at 90.6kg 17 weeks ago. I'm 68.9kg today and just starting trying to maintain.

Good luck with your journey

wordywitch · 04/04/2025 10:21

I had a panic moment this morning that I didn’t do the injection properly yesterday, that perhaps I didn’t prime it properly and therefore didn’t get the full dose. Can anyone tell me if this is what the pen should look like after one dose? Is the plunger in the right place?

Mounjaro April 2025 Starters
Incognitoburrito88 · 04/04/2025 10:23

Ok I’m officially a member of the MJ club! I took my first jab at 9:30 this morning. I was very nervous about doing it - but the instructions were easy to follow and it didn’t hurt.

Height 5 ft 7
SW 13st 7lb
GW 10st 7lb

obviously not feeling anything yet. We usually have homemade pizza for dinner and I’m on the fence about eating it tonight as don’t want to make myself feel ill. Will weigh myself tomorrow and Sunday morning but will then be away for two weeks.

it’s great reading everyone’s messages and knowing we’re all in the same boat. @GreenSalon2 good to have someone who’s injected the same day as me. I’m keen to compare symptoms and side effects (hopefully none).

off to drink a pint of water now before my usual Friday routine of driving children back and forth to various activities!

TC4 · 04/04/2025 10:23

Lundier · 04/04/2025 10:09

What concerns me, and the reason I haven't done this before, is that I'm not especially anxious about my body. I've got fat from eating and drinking too much, in my merry life, not from sadness.

I don't weigh myself or look in the mirror or take pictures or any of the other anxious stuff my friends who have bigger body issues do. I don't want to adopt these practices because I can see how unhappy they make my lovely friends. But the programme already seems to invite a lot of weighing and thinking about my body as some kind of separate thing to myself. I've always just felt like I am my body and I don't want to disassociate in this way. :/

I think I might be giving myself a complex that I didn't need. It's put me at level 1 on movement, which surprised me as I don't have a car and I live on a big hill so I walk everywhere, and climb a lot of hills. Have I lost touch with what is normal? Are most people walking 10k a day?

It sounds like you have a really good relationship with your own body which is great. You only need to weigh as often as you want to don’t you?? I’m only doing daily weighs at the moment as I want to see how I fluctuate over the month and around cycles! I’ve also got to where I am through enjoying my life as well but have got to the point where somethings were a bit of a struggle when I don’t want them to be as I want to enjoy my time with my little girl. I have seen a few photos lately that I haven’t really liked so now is the time to sort it out so I can be back to how I was.

it’s great you do lots of walking and activities - I have to do a lot of driving around or confined to one room while at work and don’t always get a proper break to allow me to get out but definitely having more energy is going to be a huge positive for me

when you say you have been out on level 1 for movement- what program is this?? Which company have you gone with?

SaddlebagSal · 04/04/2025 10:24

12 hours after my first jab and the only side effects so far are a slight headache and thirstiness. I’m tracking my food intake in my fitness pal. Not to control my calories but to be aware of how much I’m eating.

I expect once the medication kicks in I’ll lose weight easy enough as I lose 10lb without trying when I’m stressed and eat less (then put it back on when I’m ok). But I also expect that at some point I’ll plateau when my “natural” eating matches my calorie need for that weight, and then I’ll need to actively start calorie watching to continue to lose. TBH I always find it a complete faff and don’t want to be a calorie bore, but the act of recording what I eat does make me more mindful and make better food choices.

Lundier · 04/04/2025 10:24

QS90 · 04/04/2025 00:28

I have had similar thoughts - it really does feel like a transitional time! So many potential knock-ons. Changing society's attitude to food, possibly? Will it also drastically reduce the amount of diabetes / endometriosis / heart disease etc? Will our great grandchildren be agast at pictures of hoards of overweight people? Really interesting to think about.

Also, it's interesting to me, all the Big Feelings that people have about WLI and weight loss in general now. So emotive. So much weird judgment / shame etc around it. My mum is really worried / annoyed that I've started, for example. But not really for any particular reason as far as I can tell, except that "there might be side effects", same as any drug.

So interesting!

I do see a lot of shame and anger and judgment around WLI. I think we've trained a lot of people to think there's something moral about eating or not eating cake. Of course there isn't, unless you're literally taking the cake from a starving person. Moral acts are, in my view, about positive action in the world: helping others, giving away things, etc. But a lot of morality has been infused into this negative action, of self denial, suppression of desires, repression of the animal body.

I wonder if it's increased because we've let go of (or at least made socially unacceptable to discuss openly) a lot of shame around sex, so it's all been focused into food instead.

Where will it go next?

TimeToGetThin · 04/04/2025 10:34

HesDeadBenYouCanStopNow · 04/04/2025 10:20

@GreenSalon2 it sounds like you're my weight loss twin.

I'm also 54

I started at 90.6kg 17 weeks ago. I'm 68.9kg today and just starting trying to maintain.

Good luck with your journey

Wow! That’s amazing!

Have you stayed on the 2.5mg doses or did you move up to higher ones and if so when?

Lundier · 04/04/2025 10:34

@TC4 I went with Juniper. You get a doctor and health coaches. There's an exercise programme, a nutrition programme, etc. It's a bit more expensive but not loads.

I thought it looked like a good level of support and medical-ish supervision, but I'm not keen on the diet industry as it honestly looks to me like a neurosis factory. And I'm finding this a bit neurotic already! I don't mean to be rude, by the way - I know feelings are very difficult around weight stuff. I do genuinely have a good relationship with my body, or rather, I just am my body. My body is me. I've never been detached from it in the way I know happens to so many people. I don't want it to happen to me.

But yeah it assessed me as level 1 of 10 for movement, so I am on the lowest level. I walk between 8 and 15 k a day. I have a treadmill desk and no car. I just got back from a hiking holiday. So I don't know. Maybe we have to quit our jobs and walk literally all day to get to level 2?

SaddlebagSal · 04/04/2025 10:36

On the moral side, I think those fortunate people who don’t suffer from “food noise” and cravings don’t understand what it’s like to live with them. And some people can be very judgy. I once worked with someone who was naturally slim and who said they could eat what they want and stay the same weight and was bemused by those of us constantly trying to “be good”. Then they had a course of steroids and they put on a stone in the blink of an eye, and understood a bit more about other people’s appetites and metabolism not being the same.

I’ve no problem telling anyone I’m on WLI, if they ask. I’m prediabetic and insulin resistant and a BMI over 30 for decades. Diets always fizzle out after a couple of months. I need to do something different and it seems to me that this medication is targeting the root causes of why I struggle to control my appetite. Time will tell if it works for me. 🤞🏻

HesDeadBenYouCanStopNow · 04/04/2025 10:42

@Lundier a lot of us weigh to track but it isn't essential apart from when reordering as they'll ask for your weight then.

You could choose to track using how your clothes feel

You've decided you want to lose weight for a reason, does that give you something to track against? Someone mentioned feeling better able to get up off the floor from playing g with the kids, someone noted their clothes felt looser.

I've noted my calorie intake through most of my journey and that's been useful as at times it dropped a bit low and it acted as a reminder to add a bit more protein in to the next meal. I also noted when I ate less I burped more, so helped me find a remedy for burping by eating something.

I've also got the same trousers in 4 sizes (I didn't throw much away as I gained weight which is lucky), so tracking moving down through those trousers is probably more an influence than the food or weight.

I haven't taken many photos as I really didn't like them much at the beginning, but recently I was in the background of someone's photo and I didn't mind how I looked so may not shy away from pics in the future.

I hope you can have the journey you want without feeling sad of getting a complex, it's a great thing that you've avoided that 😊

I've reached the stage where I feel I'm looked not bad for my age, and that feels nice 😊

TC4 · 04/04/2025 10:49

Lundier · 04/04/2025 10:34

@TC4 I went with Juniper. You get a doctor and health coaches. There's an exercise programme, a nutrition programme, etc. It's a bit more expensive but not loads.

I thought it looked like a good level of support and medical-ish supervision, but I'm not keen on the diet industry as it honestly looks to me like a neurosis factory. And I'm finding this a bit neurotic already! I don't mean to be rude, by the way - I know feelings are very difficult around weight stuff. I do genuinely have a good relationship with my body, or rather, I just am my body. My body is me. I've never been detached from it in the way I know happens to so many people. I don't want it to happen to me.

But yeah it assessed me as level 1 of 10 for movement, so I am on the lowest level. I walk between 8 and 15 k a day. I have a treadmill desk and no car. I just got back from a hiking holiday. So I don't know. Maybe we have to quit our jobs and walk literally all day to get to level 2?

Wow that sounds intense I don’t think I’d enjoy it with pressure like that either so I can’t blame you. And that’s crazy with that much activity and they say you’re on the lowest!! I think you seem like me that you will give it a go but not much pressure. I feel like I have enough knowledge to know what’s right and what isn’t so il just go about it this way, may need more support once getting towards trying to come off and maintain where I am as I do not want to be on this forever!!

I hope you get some good results but keep strong and do what is best for you x

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