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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro Feb 2025 starters (thread 4!)

933 replies

Nicecuppatea2025 · 18/03/2025 18:03

Welcome one and all to the next instalment of our magical weight-loss journeys!

Good luck over the next few weeks. Loving all the ongoing support and encouragement.

Has anyone seen a badger? I’ve lost one!

OP posts:
Thread gallery
16
SpiralSister · 07/04/2025 11:07

I’m sorry you’re feeling low, @Zibb . I won’t give you platitudes, but a virtual hug.

sweetpickle2 · 07/04/2025 11:13

Zibb · 07/04/2025 10:57

I'm feeling very down and demotivated lately. I have such a long way to go before I'm a healthy weight and now I just keep worrying that I won't ever actually reach it. I'm not hitting any of my targets. I can't see a difference when I look in the mirror. I'm tired all the time, I've been quite mean and snappy as well. I don't feel like Zibby right now, just some miserable imposter instead.

Weigh day yesterday and after about 10? days of being stuck at 98.something the scales finally shifted.

SW: 115.8kg
CW: 96.5kg

In 7 weeks.

I should be pleased with that but i think because I can't see it or really feel it I just feel a bit crap.

I don't think 5mg agrees with my brain. I felt brilliant on 2.5mg so I'm going to go back to it I think. No point staying on 5mg and who knows what 7.5mg would feel like. I don't want to feel worse than this. I don't have any physical side effects, just the really low mood.

Need to give my head a wobble and get a grip.

I'm sorry you're feeling low- if you think the medication is causing that, then I would definitely think about going down in dosage.

You've lost over 3 stone in 7 weeks though, that's a huge amount! There is no way you won't be able to see that, even if YOU can't. Your clothes must be fitting better/too big?

Are you taking measurements around your waist etc? I find this easier to see a different sometimes than weight.

Mounjaronewbie25 · 07/04/2025 11:48

@Flamethrowers @mumandgran24
Yes "twat" is certainly one word I would use for these preachy thin people lol.

Thats interesting @aylis because some of the nastiest comments I’ve seen online have been from men!

It is true you wouldn’t expect someone to suffer through any other medical condition without treatment or medication to get it under control! I hope with time society will understand it better and become more accepting of it.

Zibb · 07/04/2025 11:53

Thank you @SpiralSister

@sweetpickle2 You're right that it is noticeable in certain ways but my brain just doesn't see it. It's just disordered thinking/body dysmorphia. Just like I never really saw how fat I was getting. I mean, I did, but I didn't. My picture of me in my head is just a bit messed up.

I do take measurements and I try to focus on the NSVs, and all the other sensible things I recommend to other people, I'm just terrible at following my own advice!

This is why this thread is so great, I am already getting a grip. I think it helps being able to confess and put my feelings out there.

Marypoppinsisnosaint · 07/04/2025 12:23

Hiya all,

Monday check in:

Sw: 17st 2lb
Cw: 15st 3lb

1st 7lb in 7 weeks, 4lb gone and this week. Seems mad I've just taken my 8th dose already!

Really didn't think I'd lost anything this week, I haven't drank nearly enough and my DH has done quite a few meals this week which was impossible to calorie count. I just stopped once I was full and it was reasonable mj friendly 🤣

Hope you all have a great week 😊

OvertiredandConfused · 07/04/2025 12:31

Zibb · 07/04/2025 10:57

I'm feeling very down and demotivated lately. I have such a long way to go before I'm a healthy weight and now I just keep worrying that I won't ever actually reach it. I'm not hitting any of my targets. I can't see a difference when I look in the mirror. I'm tired all the time, I've been quite mean and snappy as well. I don't feel like Zibby right now, just some miserable imposter instead.

Weigh day yesterday and after about 10? days of being stuck at 98.something the scales finally shifted.

SW: 115.8kg
CW: 96.5kg

In 7 weeks.

I should be pleased with that but i think because I can't see it or really feel it I just feel a bit crap.

I don't think 5mg agrees with my brain. I felt brilliant on 2.5mg so I'm going to go back to it I think. No point staying on 5mg and who knows what 7.5mg would feel like. I don't want to feel worse than this. I don't have any physical side effects, just the really low mood.

Need to give my head a wobble and get a grip.

I didn't see much movement on 5mg even though 2.5mg had been great. Doctor advised moving up to 7.5mg and it's much better with a 3 1/2lbs lost in the first week.

Like you, I have a lot to loose and can't see much of a difference. I'm still wearing the same size clothes, although a couple of pairs of trousers that were too tight now fit properly.

I had 24 hours before the second 7.5mg jab where supression wore off. Worked well for me this time as I had a couple of days where I actually ate my full calorie allowance. Injected last night and can only manage water so far today. Will try and have some fruit and a protein shake for lunch

obsessedlex · 07/04/2025 13:42

HI All
Can anyone talk to me about side effects please - My 4th 5mg dose on Friday and by friday afternoon I was completely bedridden with nausea - no actual sickness just the most horrendous nausea for the whole weekend, have only managed a couple of pieces of toast forced down each day since - how can it come out of nowhere when I havent had any other side effects at all before. The only chnage is that I did it on Friday rather than Thursday so a day later, but that should mean that the amount in my body is less and not more.... Terrified to do another 5mg jab if I am honest, I might titrate down to 3.75....

aylis · 07/04/2025 15:05

obsessedlex · 07/04/2025 13:42

HI All
Can anyone talk to me about side effects please - My 4th 5mg dose on Friday and by friday afternoon I was completely bedridden with nausea - no actual sickness just the most horrendous nausea for the whole weekend, have only managed a couple of pieces of toast forced down each day since - how can it come out of nowhere when I havent had any other side effects at all before. The only chnage is that I did it on Friday rather than Thursday so a day later, but that should mean that the amount in my body is less and not more.... Terrified to do another 5mg jab if I am honest, I might titrate down to 3.75....

Have you tried pepto bismol? I read that this is really good for most of the gastric issues so I tried it for the burping and nausea. It's pretty good - I was having a terrible time last night with nausea but a couple of swigs of pepto bismol settled things down. It feels counter- productive to eat when you feel so sick but I also find that eating something small (crackers etc) sometimes helps with the nausea. Unless my stomach is physically hurting, which has happened a couple of times. This is also on 5mg.

WLINewbie · 07/04/2025 15:24

Hello Everyone :)

Another one here struggling a wee bit with 5mg. The 2.5 was great, food noise gone but could still eat proper meals and treats, felt like a normal person. The last week on 2.5 I'd been pretty hungry so thought it was only right to go up to 5mg.

First week on 5 felt fine, similar to 2.5. From the 2nd week I started to feel higher suppression which I liked, was eating generally clean and feeling full. Took 4th 5mg dose on Saturday and feel the past week or so I've been uncomfortably full, not enjoying meals and the thought of just foods makes me feel sick. Except sweet things like fruit and chocolate 😒😒😒😒😒.

Making myself eat but struggling to get to 1000cals, never thought I'd be like that. I've been absolutely exhausted too, not enjoying the lovely sun as too tired.

Next dose I'm going to drop to 3.75 I think. Hopefully get back to the good early days and continue making gym progress.

Dozycuntlaters · 07/04/2025 15:56

Hi All

Weigh in and jab day today

SW 13st 4
CW 11st 10

I stayed on 2.5 for the first 2 pens, took my golden dose last week from my 2.5 and had enough for 3.75. I am due to start my 5 mg pen today but as I felt totally fine on 3.75 last week I am going to just do 45 clicks and keep to that for now. I'm losing 2 to 2.5 lbs a week and I'm good with that as it feels more sustainable.

I have to say, I feel very focused at the moment which is something I struggled with before MJ. I watched a really interesting thing on line last week where someone was asking a lady on MJ if her weightloss was better than when she was on SW. She said the losses were pretty similar but consistency was better on MJ and I totally agree. On SW I could lose 3 lbs, then gain 1, then stay the same. I have had a consistent loss each week since starting the jab, just easier to keep focus.

OntheTrainX · 07/04/2025 16:37

Yeah the nausea and fullness on 5mg hasn’t been pleasant. That’s why I haven’t gone up to 7.5 (third order arrived yesterday). I find chewing gum helpful. And exercise takes my mind off it although on days 1 and 2 I don’t really feel like doing any, such is the fullness and sickness.

It’s worth it though. Of that I am sure.

MatriarchCaz · 07/04/2025 17:09

This reply has been withdrawn

This message has been withdrawn at the poster's request

MatriarchCaz · 07/04/2025 17:10

Wrong thread so have asked mumsnet to delete x

Slowrunning · 07/04/2025 17:44

ivegotthekeyivegotthesecret · 07/04/2025 10:07

Good luck with it. Did you know day one is the day after you've taken your injection, as in 24 hours later. I hadn't realised that at first 😊

Nope, I assumed day 1 was the injection day rather than the day after. A lot of people seem to jab in the evening though and I might try this too and see if it helps the nausea. I’m going to do 2 mg on Saturday and another 2mg on Wednesday.

Slowrunning · 07/04/2025 17:53

Zibb · 07/04/2025 10:57

I'm feeling very down and demotivated lately. I have such a long way to go before I'm a healthy weight and now I just keep worrying that I won't ever actually reach it. I'm not hitting any of my targets. I can't see a difference when I look in the mirror. I'm tired all the time, I've been quite mean and snappy as well. I don't feel like Zibby right now, just some miserable imposter instead.

Weigh day yesterday and after about 10? days of being stuck at 98.something the scales finally shifted.

SW: 115.8kg
CW: 96.5kg

In 7 weeks.

I should be pleased with that but i think because I can't see it or really feel it I just feel a bit crap.

I don't think 5mg agrees with my brain. I felt brilliant on 2.5mg so I'm going to go back to it I think. No point staying on 5mg and who knows what 7.5mg would feel like. I don't want to feel worse than this. I don't have any physical side effects, just the really low mood.

Need to give my head a wobble and get a grip.

Zibb you have lost a massive amount of weight in a very short period of time. Are you eating plenty? If you are not getting enough calories then you will be tired, snappy and feeling down. Just remember that this is not a quick fix. As a previous poster just said the advantage of this medication is that it helps us be consistent. Maybe have another look at your TDEE to make sure you are getting enough nutrients and although you may not see a difference I can guarantee that other people will have noticed.
Mounjaro can definitely affect your mood so reduce the dose if you need to. Is there anyone who knows you are taking it that you can talk to about how you are feeling?

Zibb · 07/04/2025 19:03

Slowrunning · 07/04/2025 17:53

Zibb you have lost a massive amount of weight in a very short period of time. Are you eating plenty? If you are not getting enough calories then you will be tired, snappy and feeling down. Just remember that this is not a quick fix. As a previous poster just said the advantage of this medication is that it helps us be consistent. Maybe have another look at your TDEE to make sure you are getting enough nutrients and although you may not see a difference I can guarantee that other people will have noticed.
Mounjaro can definitely affect your mood so reduce the dose if you need to. Is there anyone who knows you are taking it that you can talk to about how you are feeling?

Thank you for this very kind response.

I know it is a lot to lose in a short amount of time. I weigh and track all of my calories carefully. I originally didn't plan to track closely but ended up doing it to make sure I was eating enough.
I eat an average of 2100 calories a day currently and my average daily calorie burn is 3200 (according to fitbit, though I know it can be wildly inaccurate). I have a fairly active job and walk about 60km a week with my dogs.
I'm very focused on my nutrition, I eat plenty of protein and fibre, lots of veg, but I struggle to eat carbs. I just don't feel great if I eat loads of them. Although I do have a wedge of cake almost every day or a pastry (I work in a bakery, the temptation is too much)!
I'm eating more now than when I first started. So with that deficit I should be losing 1kg week but it's more like 2kg. I had a big loss at the start, 6kg in 1 week, but it was literally water weight and inflammation. I was very bloated and swollen when I started MJ.
I've struggled with depression before but it's just such a drastic change in mood when I was feeling incredible on 2.5mg. Less than a week on 5mg and I noticed the low mood creeping in and it keeps getting worse.

Right, putting all my thoughts out there has just cemented my plan to go back to 2.5mg. Hopefully that will be the fix.
I don't want to go back on antidepressants, I would rather stop taking mj than do that.

Hangryfastjo · 07/04/2025 20:01

Hey @Zibb you've made me think about my mood. On 2.5 I felt really good, work stress/anxiety seemed really manageable, and nothing got to me as much.
On 5mg I feel like I'm going back to overthinking, being annoyed with people and ruminating when trying to go to sleep. It feels significant to me.
Sorry you're feeling like you are, hopefully it will pass soon.

ivegotthekeyivegotthesecret · 07/04/2025 20:30

Slowrunning · 07/04/2025 17:44

Nope, I assumed day 1 was the injection day rather than the day after. A lot of people seem to jab in the evening though and I might try this too and see if it helps the nausea. I’m going to do 2 mg on Saturday and another 2mg on Wednesday.

Yes I'd also assumed day one was the injection day.

I also jab at night as late as possible after dinner and close to bed time. I find this works well though does cause a bit of insomnia, and my sleep quality is already pretty mixed.

Nicecuppatea2025 · 07/04/2025 20:37

@Zibb you’re doing great, you really are!!

OP posts:
Ohsoverytired11 · 07/04/2025 21:20

Forgot to add my weigh in yesterday. Now on week 9. Took my 4th dose of 3.75mg. Start date 9th feb so nearly 2 months in. Another 1.8lb off this week.

SW 14st 2.6lb
CW 12st 10.8lb
Total loss 19.8lbs

Lots of people are noticing now. Feel so much different in myself. Another 8lb off and I'll be overweight rather than obese!

LaurenW · 07/04/2025 21:23

Two days in after my first 7.5mg. Side effects completely minimal in comparison to how I struggled with 5mg. I had two weeks of feeling very poorly on 5mg, but it’s been fine so far! Appetite suppression is back. Fingers crossed it stays this way.

Nicecuppatea2025 · 07/04/2025 21:44

Have not been building good habits yet at all.

Typically having an evening meal (tonight was a very yummy homemade chicken Caesar salad) and that’s pretty much it.
Yesterday was a couple of mackerel fillets for lunch, and a burger with salad and three new potatoes for dinner. Also had a cocktail and half a Gu pud.
The day before was a chicken fillet and half a bottle of Prosecco!

.. so I am all over the place. Maybe up to 7.5mg is the way to go. Anyone else having a similar problems? Or any thoughts? Written down, that diet sounds a bit shit doesn’t it!

OP posts:
Nicecuppatea2025 · 07/04/2025 22:39

LaurenW · 07/04/2025 21:23

Two days in after my first 7.5mg. Side effects completely minimal in comparison to how I struggled with 5mg. I had two weeks of feeling very poorly on 5mg, but it’s been fine so far! Appetite suppression is back. Fingers crossed it stays this way.

Thinking going up might be a good plan.

OP posts:
LaurenW · 07/04/2025 23:04

Nicecuppatea2025 · 07/04/2025 22:39

Thinking going up might be a good plan.

I was going to stay on 5, but supply issues and weight loss plateauing changed my mind. Don’t regret it at all.

MynameisJune · 07/04/2025 23:22

Nicecuppatea2025 · 07/04/2025 21:44

Have not been building good habits yet at all.

Typically having an evening meal (tonight was a very yummy homemade chicken Caesar salad) and that’s pretty much it.
Yesterday was a couple of mackerel fillets for lunch, and a burger with salad and three new potatoes for dinner. Also had a cocktail and half a Gu pud.
The day before was a chicken fillet and half a bottle of Prosecco!

.. so I am all over the place. Maybe up to 7.5mg is the way to go. Anyone else having a similar problems? Or any thoughts? Written down, that diet sounds a bit shit doesn’t it!

Not building amazing habits here yet either, but I’m in this for the long haul. It hasn’t even been 2 months for me yet. So I’m giving myself a bit of grace, my body needs to adjust but my mind needs time to figure it out too.

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