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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Weight gain on mounjaro

232 replies

Polkadotdash · 17/01/2025 10:32

Any else experience this? I’m just starting my 4th week on 2.5mg. I lost a few pounds in my first week on it, but these are back on now. I’ve had no effects at all from the injections - good or bad. I’ve already bought the 5mg dose to start next week, but I’m starting to wonder if it’s worth the cost. I bought from a big online pharmacy so I’m assuming that I haven’t been sent a placebo or anything. But it’s really doing nothing for me, apart from costing me money! Am I alone in this?

OP posts:
mollymazda · 17/01/2025 21:15

Polkadotdash · 17/01/2025 21:11

I’m reticent to ‘eat less’ because I can’t see what I can cut out without starving/getting faint. According to the calculator I already eat 200 cals less than I need. And since I’m not getting the appetite suppression from MJ that others get (yet), what do you suggest I stop eating in the meantime? Or is it the mystery calories you seem to think I’m consuming?

for example what do you eat on a normal day? have you replaced full fat milk with semi skimmed or other low fat alternatives..

you really are coming across like you intend to put no work in and expect instant results without changing anything

Polkadotdash · 17/01/2025 21:16

GirlWearsRed · 17/01/2025 21:07

But you are only on the initial dose of 2.5, so you have no idea whether MJ will do that or not. You have been told numerous times you need to step up the dose to 5mg. I have been on MJ since July last year, I've lost 6 stone in that time, I felt very little effect on 2.5mg, as soon as I moved up to 5mg it kicked in. You have barely started your MJ journey. It's not a quick fix, or a magic drug, it takes time, and yes, some willpower too.

Edited

Yes I know, welcome to the thread.
I am not disputing that I need to try the 5mg dose. If you read all the posts, I’ve said it several times. The basis of the discussion was comparing my experience with others who have lost on 2.5mg whereas I’ve gained. The chat is now on to why I’m eating as much as 2000 cals a day, which is the same as before starting MJ because MJ is having no effect on my appetite.

OP posts:
Polkadotdash · 17/01/2025 21:21

@mollymazda i put my typical daily food in an earlier post.
I don’t drink much milk (two teas and one decaf coffee a day) so reductions on that wouldn’t make much difference.
As I wrote in an earlier post, my expectation in starting mj was that I would feel fuller so eat smaller portions and not get crazy hungry before meals.
Never had food noise issues, so wasn’t needing that.

OP posts:
Polkadotdash · 17/01/2025 21:23

Kind of feel like this thread is going around in circles now.

OP posts:
mollymazda · 17/01/2025 21:24

Polkadotdash · 17/01/2025 21:21

@mollymazda i put my typical daily food in an earlier post.
I don’t drink much milk (two teas and one decaf coffee a day) so reductions on that wouldn’t make much difference.
As I wrote in an earlier post, my expectation in starting mj was that I would feel fuller so eat smaller portions and not get crazy hungry before meals.
Never had food noise issues, so wasn’t needing that.

it wont make you feel fuller? it doesnt fill you up? it surpresses your appetite? but... i wish you well

mollymazda · 17/01/2025 21:26

Polkadotdash · 17/01/2025 21:23

Kind of feel like this thread is going around in circles now.

only because you are refusing to accept that you need to put some work into your weight loss journey rather than expect it to just happen.

you know you need a calorie deficit of 500 a day, yet you refust to do that. weight loss is very simply, its calories in verses calories out.

you are sitting there, taking your injections, refusing to change your liefstyle and then wondering why it wont work

Polkadotdash · 17/01/2025 21:27

mollymazda · 17/01/2025 21:24

it wont make you feel fuller? it doesnt fill you up? it surpresses your appetite? but... i wish you well

I’m not following you. Are you saying mj doesn’t make you feel fuller or suppress your appetite so I shouldn’t have expected that?

OP posts:
IDontHateRainbows · 17/01/2025 21:28

I lost a stone which came off quite quickly once I came off the starter dose, I was eating vast amounts of food before and now eat a fraction of what I was but the weight loss has stalled. I was prescribed it for diabetes so only had 2 stone to lose, if I can get the second stone off great if not the health benefits and getting back in my old clothes has been worth it plus it hasn't cost me a penny in fact I'm quids in as food spending has gone right down plus I've saved on buying clothes.

Polkadotdash · 17/01/2025 21:29

@mollymazda you’re really not making sense now. Of course weight loss is more calories out than in. If I could easily do that, I wouldn’t need a weight loss drug.

OP posts:
mollymazda · 17/01/2025 21:33

Polkadotdash · 17/01/2025 21:27

I’m not following you. Are you saying mj doesn’t make you feel fuller or suppress your appetite so I shouldn’t have expected that?

it does not make you feel fuller...

...what it does is suppress your appetite! so it makes you not want to eat as much!

but you have to learn to listen to the signals... you can still 'eat through' them! It makes you not want to eat! and i know its sounds the same but i assure you its not..

GirlWearsRed · 17/01/2025 21:33

Polkadotdash · 17/01/2025 21:16

Yes I know, welcome to the thread.
I am not disputing that I need to try the 5mg dose. If you read all the posts, I’ve said it several times. The basis of the discussion was comparing my experience with others who have lost on 2.5mg whereas I’ve gained. The chat is now on to why I’m eating as much as 2000 cals a day, which is the same as before starting MJ because MJ is having no effect on my appetite.

2000 calories IS a lot if you are wanting to lose weight.

If your TDEE is 2200, aim for 500 less a day, so 1700. That will give you a deficit of 3500 a week which should result in at least 1lb a week loss, you may find its more. Adjust & recalculate as the weight comes off. You unfortunately may/will need to use willpower whilst you find the dose that is right for you. Some find that to be 5mg, others 15, like I said it's a journey, everyone's body is different.

Once you do get the right dose though it will be like a switch has been flipped and it will be a VERY noticeable change. You ARE/WILL still essentially be on a diet, but you won't have the hunger, cravings, etc that you would have just with dieting alone. You will find dieting easy/easier. That is the point of MJ, you just clearly are not on the right dose yet and that's literally your answer that's been given to you by people including myself who have been on MJ for a long time with months and months of experience and success. There's not much else anyone can tell you other than stick with it.

PsychoHotSauce · 17/01/2025 21:34

It sounds like you missed what MJ actually does before you bought it. Dieting is hard, you get hungry. You're still supposed to diet on MJ, the jabs just make it easier. It's a long process, and it's not some miracle fat cure!

It's a tool to aid dieting, you do actually have to try and reduce your calorie intake. You seem to have thought that somehow you could eat the same and it would 'aid weightloss'. It doesn't.

You're also fucking with your blood sugars a lot with all the carbs you eat, then feeling faint during a crash, so you need to eat more. Can't you see how you're sabotaging yourself and throwing money down the train by refusing to work with the jab to stabilise your blood sugar?

Also, if you're only in a 200 calorie deficit that doesn't give you much leeway if you miscalculate/guesstimate some things. Depending on what app you use, they're not always accurate either, you have to check closely. Most of us tend to underestimate the calories we eat, even with the best of intentions, meaning we're not in the deficit we thought we were.

You seem quite closed to the idea of eating less and eating differently, as if somehow expecting MJ to do all the work. You won't 'starve' if you eat a bit less. Your body will draw on your fat stores for energy. Reduce the carbs and eat nutritious food and you won't feel faint.

mollymazda · 17/01/2025 21:35

Polkadotdash · 17/01/2025 21:29

@mollymazda you’re really not making sense now. Of course weight loss is more calories out than in. If I could easily do that, I wouldn’t need a weight loss drug.

i'm out!

GirlWearsRed · 17/01/2025 21:38

mollymazda · 17/01/2025 21:33

it does not make you feel fuller...

...what it does is suppress your appetite! so it makes you not want to eat as much!

but you have to learn to listen to the signals... you can still 'eat through' them! It makes you not want to eat! and i know its sounds the same but i assure you its not..

I'm not sure you fully understand how MJ works either. It literally DOES make you feel fuller. The whole process of GLP-1 is that it mimics naturally occurring peptides that send messages to the brain that you are satiated and no longer want to/can eat anymore, resulting in you wanting to eat only small portions.

Polkadotdash · 17/01/2025 21:41

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Weepixie · 17/01/2025 21:43

@Polkadotdash reduce your calorie intake down to 1700 per day which is a deficit of 500 from your TDEE. Just try it for a couple of weeks. We can help with some meal planning if you like but using an app like nutracheck or mfp would also help you. 1700 calories per day is a really good amount of food to eat.

mollymazda · 17/01/2025 21:44

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i beg your pardon? you are refusing to listen to anything anyone is saying.. all you basically want is for someone to come on here and say

'hey its ok, when you are on the higher does it'll just fall off you!' and are refusing to see the bigger picture with these injections.

you're only happy i was going because you knew i was actually talking sense!

Polkadotdash · 17/01/2025 21:45

@PsychoHotSauce I wasn’t expecting to eat the same. I was expecting to want to eat less. To stay fuller longer so I didn’t snack. To be happy to not have breakfast. What I didn’t expect was to put weight on.

OP posts:
Polkadotdash · 17/01/2025 21:45

mollymazda · 17/01/2025 21:44

i beg your pardon? you are refusing to listen to anything anyone is saying.. all you basically want is for someone to come on here and say

'hey its ok, when you are on the higher does it'll just fall off you!' and are refusing to see the bigger picture with these injections.

you're only happy i was going because you knew i was actually talking sense!

Ah you’re still here then 🙂

OP posts:
mollymazda · 17/01/2025 21:47

Polkadotdash · 17/01/2025 21:45

Ah you’re still here then 🙂

i am.. and you are still refusing to listen.. report me all you like, makes a lot of sense now to be honest...

i will say it until the cows some home... you need to be in calorie deficit to lose weight, doesn't matter what chemicals you put in your body, you still have to take some personal responsibility and at least TRY.. and give it more than 3 weeks before complaining that its not working

GirlWearsRed · 17/01/2025 21:49

Polkadotdash · 17/01/2025 21:45

@PsychoHotSauce I wasn’t expecting to eat the same. I was expecting to want to eat less. To stay fuller longer so I didn’t snack. To be happy to not have breakfast. What I didn’t expect was to put weight on.

To address the gaining weight thing, weightloss is not linear, even on MJ, you have will losses, you will have gains, you will have plateaus even ON Mounjaro. There are a number of reasons for this, time of the month for example. But everytime I have gained it has dropped off at the next weigh in.

Not being hydrated enough is a BIG cause of people gaining on MJ. The old saying "the more you drink the more you shrink" is spot on, because we literally pee out our metabolised fat. Are you drinking enough? Aim for at least 2ltres of water a day. It is so important.

I think you have unrealistic expectations of what MJ will and can do and you were always going to be disappointed because it seems like you expected it to magically start dissolving your fat and that is not what it does. You have had so much good advice and replies and yet you're taking none of it in.

Gettingbysomehow · 17/01/2025 21:52

Shrinkingrose · 17/01/2025 10:35

No, you won’t be alone, 15 percent of people it has no impact on at all it doesn’t work for them. So I’d try the 5 and if it doesn’t work, then stop, but 5 maybe might work. Good luck.

2,5 is just initiate treatment, it’s not even a full dose, and is not supposed to cause weight loss, of course it does in many but in it not doing so, you’re far from alone.

Wow is it that much? 15%? Mine worked almost immediately. I could have stayed on 2.5 for much longer.
It seems to have had an accumulative effect as well.

PsychoHotSauce · 17/01/2025 21:57

Polkadotdash · 17/01/2025 21:45

@PsychoHotSauce I wasn’t expecting to eat the same. I was expecting to want to eat less. To stay fuller longer so I didn’t snack. To be happy to not have breakfast. What I didn’t expect was to put weight on.

OK. You're supposed to diet, with MJ to help you. All the things you found hard about dieting before the jabs? They won't be as hard, but you still need to apply yourself to losing weight. And considering MJ is working bloody hard at stabilising your blood sugars and you're working equally hard at throwing them out, maybe have a think about whether you're willing to make the changes so the jab actually works for you, or whether you'll just quit and tell everyone you were one of the unlucky special ones with the heavy bones and the bad genes that it 'doesn't work for'.

TakeMeToKernow · 17/01/2025 22:10

OP, I’m the same as you. I’ve just done the 4th injection of 5mg and I’ve gained about 2.5lbs since starting.

I think I’m feeling the smallest bit of effect now (I took the 4th injection 2 days early) and I’m going to see if 7.5mg has an effect.

I have also had spells on ozempic and wegovy. Wegovy was the easier to persist with (less side effects) but bugger me, ozempic was like a MAGIC WAND. Honestly, magic.

I wasn’t expecting to eat the same. I was expecting to want to eat less. To stay fuller longer so I didn’t snack. To be happy to not have breakfast.

What you’ve described here is EXACTLY what happened when I tried ozempic and wegovy. And lost nearly 3 stone that way. I switched to MJ because of price, but I wonder if it has been a false economy.

Shrinkingrose · 17/01/2025 22:13

Gettingbysomehow · 17/01/2025 21:52

Wow is it that much? 15%? Mine worked almost immediately. I could have stayed on 2.5 for much longer.
It seems to have had an accumulative effect as well.

Yes in clinical trials it was 15 percent.

to the poster who keeps havering on it doesn’t make you feel fuller. It does, it slows your digestion so you feel fuller for longer, and it also triggers your brain to feel satiated, that’s how it works.

however op, the poster is right, 200 cals a day under isn’t going to do it for you, if you’re very rigid and ensure your tdee is absolutely correct and your cal intake is, so it’s absolutely 200, then that would see you lose less than half a pound a week. You need 500 under for a lb a week.

i don’t think you’re in the right head space for it. You want your food, and that’s ok, but you won’t lose weight. As you are not now, as clearly you are not exact with your 200 under, you’re gaining. And to gain a pound a week you are earring 500 a day over, so if you’re bmr is 2200, then you eat an average of 2700. No way round this. If you gain 2 lbs in a week, you’ve over ate by 1000 cals a day, so 3200. Again, no way round this, you’ve gained, so you’ve eaten way more cals than you think

for some reason yoh keep posting you’re undereating and refusing to accept that if you’re gaining then you are over eating.