Mounjaro September Support (4)

[EatingTillIDie]

A new thread before the old one fills up!

Those of you who are still on 2.5 - is it because of side effects? Surely worth trying a 5 pen before giving up?

out of nowhere I’m having crazy suppression this week. It’s a mystery as it’s my third pen at this level, and it’s been tailing off loads. Ate a boiled egg earlier and felt fuller than I did after christmas dinner!

It's weird how it seems to come and go isn't it

@MissBPotter my TDEE is around 1600cals so around 1000 should be fine for losing weight. I have always lost very slowly through, that is one of the main reasons I turned to MJ. My usual diet process was to lose about 2lbs in 6 weeks, then go out for dinner and gain it all back again in a night!

@EBoo80 I've not struggled too badly with side effects, but I get quite high suppression to the point that I have to force myself to eat in the first few days after the jab. I want to go up as I think eating less than I currently do wouldn't be healthy. I'm certainly not planning on quitting as this is working better than anything else in the past, but I think I just have to accept that it won't be as quick as some others and it may be a while before I reach my goal.

@EBoo80 I had good supression on 2.5mg and stuck there for a couple of pens. Started creeping up the doses in November. The level of supression was high and I felt I was making excuses to ther people for not eating well when I visited, and on holiday just sitting staring at a plate of food having nibbled at my starter. When I eventually took the full 5mg I felt so awful, couldn't think about food and had to cancel friends coming for lunch and another event. I went back down to 2.5mg for the 2 weeks over Christmas to make it manageable.

I'm back up to 3.3mg (30 clicks again) and will do 35 clicks for my next jab. It is so weird how we all react differently. I see people taking 12.5mg and heading for 15mg. I just cannot imagine that would ever work for me.

@20bloodypounds you sound quite similar to me, although I haven’t braved 5mg to know how it would affect me yet!

It’s amazing how individual it is. I would love to understand the science behind that better.

@EBoo80 It's fascinating isn't it? It makes me wonder whether there's similar variation for other medications. I never really got on with hormonal contraceptives, the impact on my mood was horrendous. Yet other people are fine.

I also wonder if because so many of us are taking this on private prescription and engaging on forums like this, whether we are taking more control of how we manage the doses and the impact. A friend of mine was prescribed Wegovy by her GP, and followed the path for increasing doses. I recently heard she'd stopped, because of the side effects. Maybe if she'd felt more in control of that herself she'd have titrated up more gradually, rather than blindly following her doctor's instructions. A busy overworked GP is understandably going to be following standard guidelines, not researching the ins and outs of microdosing.

I certainly imagine that if I had been part of an MJ clincial trial, with a set protocol and no flexibility I'd have dropped out of the trial as soon as there was the first dose increase to 5mg. It wold have been recorded as adverse side effects. There's no room in an ethically approved trial to start messing around with the doses.

This is more like citizen science where we are all contributing our own experiences to a body of data. It is interesting to see how that data is being used - for example some pharmacies offering more flexible options around maintenance, whereas the mainstream large clinical trials followed a standard path of increasing to 15mg and maintaining on that dose, even once a BMI of 25 had been achieved.

I watched a youtube video about microdosing on MJ. The presenter was describing the vast number of GLP 1 receptors across the body: panceas, brain and stomach being the key ones for the mechanism that results in appetite supression, satiety, and leads to weight loss. But there are also receptors in the kidneys, heart, blood vessels. I can only assume that there is a normal human variation in a) the number of receptors that individuals have; and b) the sensitivity of those receptors.

Am I being thick but how is 3.3mg 30 clicks. Of what strength one? Sorry if it's a daft question 😆🤣

Hi everyone,

I fully subscribe to the January comfort food eating mentality and trying not to give in. My scales have broken and it's interesting how much more I'm eating without the reward / check and balance of the scale moving down / up. I've ordered another set to arrive soon. It will be nearly 2 weeks without weighing w Christmas travel.

Separately, my GP has ordered bloods due to my hair loss. I will report back whether it's an underlying nutritional deficiency highlighted by weight loss or MJ itself when I get the results back. Love this idea of citizen science indeed.

Good weekend all!

Ach! I posted the wrong thing. 40 clicks of a 5mg pen = 3.3mg. That's what I did. I'll go up to 45.

I woke up really hungry this morning. In fact, that is what woke me up.

Week 17
Lost 3lbs this week. I think this is the post I have ever lost in a week.

Total weight loss 2 stone 9lb 16.2%.

I don't feel thirsty at all on MJ. My appetite has decreased on 7.5mg. the food noise is quieter.

I am so grateful to be able to take MJ. I can almost see myself overweight then a normal weight. That would not happen without MJ. I do think I will be more mindful about what I consume. I may always take a GLP1 to stay in a healthy weight range. It is too far away to think about.

@20bloodypounds ah I see 😆 I was on forty clicks of my five pen last week and have braved 45 this week too 👌🏽

I'm now 3 stone 8.5lb down since the 10th of September! So happy and I'm now only 1.5lb away from dropping into the next stone bracket and then I won't be far away from 4 stone loss. The little milestones are keeping me happy!

That’s brilliant @SpaceFairy8 👏

I’ve been a little slower than others, but after a few weeks of the same 2lb coming on and off, I dropped 5lbs and it’s stayed off for about a week now 🙏🏼 2 and a half stone down since starting MJ 🙌🏼

Hi all, hope you are all ok. I’m 2 pounds down this week and now 4 pounds from my target. I’m just about to order my last pen which means I’ll be stopping MJ at the end of February. Hopefully I’ll be at target then! I went up to 45 clicks of a 5 pen and suppression felt strong this week. I am very interested as to how I’ll navigate everything post MJ.

It would be great to hear about your experience stopping Mj @Seldomseenkid

Well done to you on your 5lb loss@GoldieLocks09.

Nearly 4 stone loss is awesome @SpaceFairy8. I have lost a stone less than you over the same timescale and am up to a 7.5mg. I check in on the slow losers board and know I am lucky really. It is strange how differently MJ impacts individuals.

@MandarinDentistTiger that is still an amazing loss!!! How are you finding 7.5mg I jump up for my next pen in a week and I'm sooooo nervous!

Very exciting @Seldomseenkid! It must feel so good to know you are almost at target, what an achievement! You will definitely have to keep us posted on how you get on once you finish, I think we are probably all starting to think about life after MJ.

How are you getting on with c25k @85reasons? I started week 2 today, still feeling quite easy but I remember that it starts to step up quite quickly!

Had a dig through my photo archives today and found a load of pics I took a year ago to try to motivate myself to lose weight. I redid them all today to compare and contrast. Obviously toning is a serious need but there's definitely a difference after 4 months on Mounjaro.

Gah - terrible weigh in this morning, and back up 3lb to where I was early December. Salty dinner last night and water retention is probably to blame for some of it, but I need to go back to basics for a couple of weeks.

@InfoSecInTheCity well done, I kind of wish I'd taken photos like that. All I have are the ones I took to get my first MJ prescription and I was trying to hide as much as possible!

@EBoo80 do you know why? (apart from the salt and water retention). Have you been eating bigger portions, or the wrong type of food? However, the good thing about MJ is that you can be sure it will come off. On a regular diet that kind of frustrating weigh in can result in falling off the wagon completely (at least that's what happens to me).

I was pretty relaxed over Christmas, so it’s not a total surprise but seems delayed… as well as half a pizza last night I had wine on Friday (rarely drink), and my cycle isn’t very regular so it could be I’m closer to my period than I thought…
Will do daily weigh ins this week to keep a track, and am guzzling water likes it’s going out of fashion today.
But I think it’s probably a good wake up call (was meant to be transitioning to maintenance at end of this month) that I have to take calorie deficit seriously.

Great pictures @InfoSecInTheCity. I'm at my halfway point so will take some photographs now. I'm mostly using clothes I used to fit into to track progress.

@SpaceFairy8 I have had no issues going up doses. I have been slower at losing but not many side effects.

@EBoo80 I find I am bloated and retain water for two days after my jab. I always put a few lbs off but lose on the week overall.

I’ve lost the weird early January gain finally and am now down another half pound - it all counts.

I thought this was interesting though. I’ve been trying to concentrate on strength/weighs exercise and this is the graph of the change in my percentage body fat since I started MJ. I know scales aren’t accurate for this but this is consistent from the same scales so it must count for something. I think it’s a good reminder of the inner healthy changes we are making to our bodies.