I'm really interested in the discussion about cortisol. @Mounjaropen do you happen to know which segment of R5Live it was on?
I've got PCOS and it has got harder to lose weight as I got older. Then Gestational Diabetes leading to pre-diabetes (I was on the cusp of T2 but reversed it be drastically cutting carbs). I strongly suspect I've got some insulin resistance going on.
I spent a good 3 months of this year in a consistent calorie deficit, plus exercise, and lost nothing. I spoke to my GP who did some blood and hormone tests but everything came back normal. I used to joke that I could eat 3 plain salads a day and still gain weight. So the comment about lettuce really resonates!
I have a completely non-qualified theory that mounjaro is working well for me because I have the conditions it is designed to help with. Not suggesting that it doesn't work for others, but it helps me to understand why this works when nothing else did