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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro October starters - Thread 5!

1000 replies

Fizzleawayy · 26/11/2024 22:57

Thread 4 is nearly full so making the next one so we can all carry on chatting ☺️

OP posts:
Thread gallery
21
Vegemite123 · 14/12/2024 21:20

Thank you @Tohaveandtohold , @Losingthetimber , @Pegsmum and @TheChosenTwo for your comments about the red patches.

Last week I did wonder if it was the different brand, but as the gauge and length are identical it seems unlikely.

I have always alternated thighs, worrying that the side effects might be worse in my tummy. But I wonder if I have a poor technique - I try to pinch the front of my thigh, but it is fairly solid and and hard to maintain hold of it! Grabbing a stomach roll would be easier.

Gr3atEscape · 14/12/2024 21:22

Vegemite123 · 14/12/2024 21:15

Yes! It’s just so freeing to not constantly be thinking about food! I went to a drinks party last night - had one drink, zero snacks and didn’t feel at all deprived. It’s so much more peaceful.

Peaceful is a great word for it

Fizzleawayy · 14/12/2024 22:07

@ChaosDream @letshavetea The dress was from new look but I picked it up in June in the sale for £11 and they don’t have it anymore.

I never buy their stuff full price but now and again they have something that’s decent in the sale.

OP posts:
Fizzleawayy · 14/12/2024 22:14

Also I discovered these in Aldi, 217 calories for this one and 99p. It’s the perfect size for our smaller appetites and it only takes 1 min in the microwave.

I know pasta is quick and easy to make ourselves but honestly I like seeing the calories on the packet and I like that I can grab them for lunch at work when I am running late for work in the morning 🤣

I sometimes chuck some chicken chunks in it to bulk it out and add protein.

Mounjaro October starters - Thread 5!
OP posts:
JustKeepsBreathing · 15/12/2024 00:22

Vegemite123 · 14/12/2024 21:20

Thank you @Tohaveandtohold , @Losingthetimber , @Pegsmum and @TheChosenTwo for your comments about the red patches.

Last week I did wonder if it was the different brand, but as the gauge and length are identical it seems unlikely.

I have always alternated thighs, worrying that the side effects might be worse in my tummy. But I wonder if I have a poor technique - I try to pinch the front of my thigh, but it is fairly solid and and hard to maintain hold of it! Grabbing a stomach roll would be easier.

You don’t need to pinch the skin with the uk KwikPen- just slide it straight in x

igivein · 15/12/2024 06:47

Weigh-in day for me and a disappointing, but not unexpected, no change. Which is a big shame because I’m 2lb away from a three stone loss. I really hope I can hit it before Christmas.
It would be just my luck to plateau now - I’m 11 weeks in and I’ve lost 15% of my starting weight so it’s bound to happen soon, but I’m really hoping the no loss has more to do with a couple of meals out and the work’s annual mince pie tasting …
I jabbed yesterday with 5mg (a move up from 4.5 last week) and I’m actually hungry this morning - what’s that all about!
This was the second dose out of my second 5mg pen. I’ve been gradually creeping up from 3.75mg over the two pens. I’ll get another three doses out of this pen and then I think I’ll need to move up to 7.5, which is a shame as I would have liked to stay on 5mg for longer, but I don’t think it will work. I want to progress slowly through the doses as I’ve such a lot to lose and don’t want to reach the maximum dose and it stop working whilst I’m still obese.

Anyway … stats for this week:

SW 20st 2lb
CW 17st 4lb

Loss this week: 0lb 😒

WafflingDreamer · 15/12/2024 06:54

igivein · 15/12/2024 06:47

Weigh-in day for me and a disappointing, but not unexpected, no change. Which is a big shame because I’m 2lb away from a three stone loss. I really hope I can hit it before Christmas.
It would be just my luck to plateau now - I’m 11 weeks in and I’ve lost 15% of my starting weight so it’s bound to happen soon, but I’m really hoping the no loss has more to do with a couple of meals out and the work’s annual mince pie tasting …
I jabbed yesterday with 5mg (a move up from 4.5 last week) and I’m actually hungry this morning - what’s that all about!
This was the second dose out of my second 5mg pen. I’ve been gradually creeping up from 3.75mg over the two pens. I’ll get another three doses out of this pen and then I think I’ll need to move up to 7.5, which is a shame as I would have liked to stay on 5mg for longer, but I don’t think it will work. I want to progress slowly through the doses as I’ve such a lot to lose and don’t want to reach the maximum dose and it stop working whilst I’m still obese.

Anyway … stats for this week:

SW 20st 2lb
CW 17st 4lb

Loss this week: 0lb 😒

I know it's dissapointing but you've lost a huge amount so far, must be around 40lbs right? In 11 weeks that's still an average of more than 3.5lb a week which is amazing.

igivein · 15/12/2024 07:10

Thanks @WafflingDreamer . I know, 40lbs is amazing and I’m feeling the benefits of it every day. I think I’d got into the mindset that the weight loss is automatic each week and I’m panicking a bit that the magic might be gone now. I know that’s not rational, but I’m in the last chance saloon as far as weight loss is concerned (post menopausal, battled obesity my entire life).
Time to give my head a shake and climb back on the wagon …

ItsMintUpNorth · 15/12/2024 07:25

@igivein drink a shit load of water today and tommorow and I bet those 2lbs could be gone. I am pretty certain it will be water weight from the saltier food eating out, I am 3lbs up this morning from my Thursday weigh in but I know it's from the food and drink I've had the last couple of days.

ItsMintUpNorth · 15/12/2024 07:30

So on that note my official week 11 weigh in I am 1lb up since last week but I am really classing it as a 2lb loss before the eating and drinking to excess!

SW: 17st 4
CW: 16st 3 or 16st on Thursday Grin

Week 2 on 7.5 has been absolutely fine with no side effects again, I think I'll order a new pen sooner rather than later so it doesn't get held up by Christmas delays so going to go 7.5 again and hope for the best.

igivein · 15/12/2024 07:36

Thanks @ItsMintUpNorth I’ll definitely give it a go. I don’t have any ‘social eating’ to do until Friday so I’ll try to have a sensible week and hope it does the trick.

Losingthetimber · 15/12/2024 07:42

igivein · 15/12/2024 06:47

Weigh-in day for me and a disappointing, but not unexpected, no change. Which is a big shame because I’m 2lb away from a three stone loss. I really hope I can hit it before Christmas.
It would be just my luck to plateau now - I’m 11 weeks in and I’ve lost 15% of my starting weight so it’s bound to happen soon, but I’m really hoping the no loss has more to do with a couple of meals out and the work’s annual mince pie tasting …
I jabbed yesterday with 5mg (a move up from 4.5 last week) and I’m actually hungry this morning - what’s that all about!
This was the second dose out of my second 5mg pen. I’ve been gradually creeping up from 3.75mg over the two pens. I’ll get another three doses out of this pen and then I think I’ll need to move up to 7.5, which is a shame as I would have liked to stay on 5mg for longer, but I don’t think it will work. I want to progress slowly through the doses as I’ve such a lot to lose and don’t want to reach the maximum dose and it stop working whilst I’m still obese.

Anyway … stats for this week:

SW 20st 2lb
CW 17st 4lb

Loss this week: 0lb 😒

It doesn’t stop working. That’s a TikTok /social media myth I’m afraid, and not why you move up the doses.

you start low, to build up tolerance, you move up every four weeks, and you keep moving up, the full dose is 15mg.

The optimal and correct dose for any individual is the dose below the one they can’t tolerate (which I get is a bit of a shit way to find out, but we all know there are ways to find out as we move up) and then you stay on that optimal dose for you for however long you need, including life. It does not stop working, it works for ever.

the reason it stops working at lower doses is you’re not on the correct dose, it’s just too low. And people have been dragging out the lower doses thinking it stops working, when it doesn’t, and I guess to save money etc,

if we think logically, of course it doesn’t stop working, it’s approved for diabetes, and about to be for cardiovascular and kidney disease, if it stopped working people would die.

I think basically people on social media got confused, and started purporting this myth that you had to move up slowly as it stopped working, simply as they didn’t under stand why you moved up each month, what the dosing schedule was, or how the drug worked. And as usual. Didn’t think logically about that, because of course it doesn’t stop working when you’re on the correct dose. How could it. It would literally kill people. And of course would not be approved for life for weight loss.

the stop working myth also came from the 2 years approval to use , for wegovy and ozempic, and as you reach a plateau where you have lost a certain percentage of weight and can’t lose more. But that’s also not quite correct on the latter, as cals in impacts.

so just,move up the doses, follow the manufacturer’s guidelines, and don’t be concerned, it genuinely doesn’t stop working. That’s just the usual social media hysteria. ☺️

igivein · 15/12/2024 08:08

That’s really interesting @Losingthetimber . I was thinking it was more like opioids, where your tolerance increases and you need more to achieve the same ‘hit’.

Losingthetimber · 15/12/2024 08:16

igivein · 15/12/2024 08:08

That’s really interesting @Losingthetimber . I was thinking it was more like opioids, where your tolerance increases and you need more to achieve the same ‘hit’.

No that’s not what this drug is. And if you think about it logically. There is no way any of the global regulatory authorities would ever, ever approve and license such a thing. Or approve a drug you could keep taking that no longer worked.

the drug doesn’t ever stop working, the issue is people don’t follow the manufacturers guidelines, don’t move to the correct dose for them, and for them, it of course stops working at each point on the way up , as they do months on the wrong dose.

in addition some people don’t follow the guidelines on what to eat, which is very clear, so they then deal with gastro issues, and they also multiple dose, ie micro dosing.

it’s all a bit crazy really and social media can be very damaging. There is clearly no risk if you just keep taking below your correct dose, other than it’s led some Ill. Informed folks on Tik tok, twitter etc to then spread the mis info that mounjaro stops working, these drugs have been extension tested, and in use for decades. And as said, not one regulatory authority, from the fda on, would ever ever approve a drug for life when it stopped working or that you had to keep consuming more and more, as the risk with the latter would be enormous, as some fools would then start dosing on 20mg, or 25 etc.

rockingbird · 15/12/2024 08:25

Morning all, stepped on the scales this morning.. wasn't expecting much! 1lb down.

SW: 11.13
CW: 9.13

So onto week 8 (jab day yesterday) I did 45 clicks of the 5mg pen as suppression seemed to have worn off recently on 2.5mg.

Goal weight is 9st and I'm hoping to hit that by early March as a birthday present to myself!

igivein · 15/12/2024 08:38

Well done @rockingbird !
I think it’s worth acknowledging that’s a two stone loss 👏👏👏

Losingthetimber · 15/12/2024 08:40

Well done rocking bird, you must feel and look amazing. !

rockingbird · 15/12/2024 08:46

igivein · 15/12/2024 08:38

Well done @rockingbird !
I think it’s worth acknowledging that’s a two stone loss 👏👏👏

Oh yeah  I hadn't registered that bit!! Frick me. My swim suits are going down in size for sure..but still hiding away in my fat clothes.

lickycat · 15/12/2024 09:11

Losingthetimber · 15/12/2024 08:16

No that’s not what this drug is. And if you think about it logically. There is no way any of the global regulatory authorities would ever, ever approve and license such a thing. Or approve a drug you could keep taking that no longer worked.

the drug doesn’t ever stop working, the issue is people don’t follow the manufacturers guidelines, don’t move to the correct dose for them, and for them, it of course stops working at each point on the way up , as they do months on the wrong dose.

in addition some people don’t follow the guidelines on what to eat, which is very clear, so they then deal with gastro issues, and they also multiple dose, ie micro dosing.

it’s all a bit crazy really and social media can be very damaging. There is clearly no risk if you just keep taking below your correct dose, other than it’s led some Ill. Informed folks on Tik tok, twitter etc to then spread the mis info that mounjaro stops working, these drugs have been extension tested, and in use for decades. And as said, not one regulatory authority, from the fda on, would ever ever approve a drug for life when it stopped working or that you had to keep consuming more and more, as the risk with the latter would be enormous, as some fools would then start dosing on 20mg, or 25 etc.

This is really interesting to read. And has made me wonder about my decision to stay on 5mg pen for another month. I was taking advice from my prescriber, though, who suggested that as I was losing weight and doing ok on 5mg, there was no reason to ‘move up’. Wondering now if that advice was incorrect (and after years navigating HRT, I’m primed to suspect prescribers of not having the full and correct information).

NearlyNewHip · 15/12/2024 09:18

My chemist explained the dosing in the same way as @Losingthetimber. I didnt take everything in at the time (excitement...wanted to get home to jab and start) and knew I can ask again when needed .
It was something along the lines of move up the doses, the only reason for sticking on the lower doses is tolerance. You then just stay on 15 mg pens (if you tolerate that dose) until you're done and then move down to maintain, dropping down in pens until you hit the balance of being able to manage without putting on or losing, which may be any of the lower pens, for the foreseeable.
I have a goodly chunk to lose (4.5 stone from when he weighed me) so he estimated that I'd prob go all the up to 15, for someone with less to lose they may hit their target along the way of tritating up and his advice may have been different x

Fizzleawayy · 15/12/2024 09:27

rockingbird · 15/12/2024 08:25

Morning all, stepped on the scales this morning.. wasn't expecting much! 1lb down.

SW: 11.13
CW: 9.13

So onto week 8 (jab day yesterday) I did 45 clicks of the 5mg pen as suppression seemed to have worn off recently on 2.5mg.

Goal weight is 9st and I'm hoping to hit that by early March as a birthday present to myself!

Well done! 2 stone off and in the 9s! What an achievement!

OP posts:
NearlyNewHip · 15/12/2024 09:28

My chemist is really my chemist and had all of my prescriptions pulled up as we were chatting about things (currently pain meds and HRT) and said he'd always check and give me a call if something new was added that he thought would need another look because of MJ

Fizzleawayy · 15/12/2024 09:33

lickycat · 15/12/2024 09:11

This is really interesting to read. And has made me wonder about my decision to stay on 5mg pen for another month. I was taking advice from my prescriber, though, who suggested that as I was losing weight and doing ok on 5mg, there was no reason to ‘move up’. Wondering now if that advice was incorrect (and after years navigating HRT, I’m primed to suspect prescribers of not having the full and correct information).

I was also told by my prescriber that there was no need to go up the doses if you find one that works for you and that you can stay at one for a 2/3 pens if needed.

If would be interesting if the above was posted on the main board to get a broader idea of what other prescribers are telling people. Very interesting.

OP posts:
Fizzleawayy · 15/12/2024 09:41

ItsMintUpNorth · 15/12/2024 07:30

So on that note my official week 11 weigh in I am 1lb up since last week but I am really classing it as a 2lb loss before the eating and drinking to excess!

SW: 17st 4
CW: 16st 3 or 16st on Thursday Grin

Week 2 on 7.5 has been absolutely fine with no side effects again, I think I'll order a new pen sooner rather than later so it doesn't get held up by Christmas delays so going to go 7.5 again and hope for the best.

Glad you are getting no side effects on 7.5! I’m ordering my next pen tomorrow, I still have a whole 7.5 to use but I want to make sure I got a spare over the Christmas and new year period, just incase.

OP posts:
Losingthetimber · 15/12/2024 10:03

lickycat · 15/12/2024 09:11

This is really interesting to read. And has made me wonder about my decision to stay on 5mg pen for another month. I was taking advice from my prescriber, though, who suggested that as I was losing weight and doing ok on 5mg, there was no reason to ‘move up’. Wondering now if that advice was incorrect (and after years navigating HRT, I’m primed to suspect prescribers of not having the full and correct information).

That’s not necessarily wrong though, as 5mg maybe the right dose for you.

im also wary of some “prescribers” though, as often it’s a customer service person responding, who has little to no training and isn’t medically qualified. Rather than any medically qualified person.

I swear though, social media will end up killing someone one day, due to th4 amount of shite and misinformation that is posted. Mounjaro stopping working being a key one. It’s bullshit and defies any form of logic, it simply stops working if you’re on too low a dose and the wrong one for you.

the right one is the one below the one you can’t tolerate, and the doses are 5 10 and 15, the .5 doses are just prep to get you there.

the other nonsense folks post is that they didn’t test the .5 doses so don’t know. Which if you think about it, the decades of testing, the stringent requirements, is utterly nonsensical. The thought any regulatory body would approve and licence drugs where the manufacturer didn’t bother their arse testing different levels is crazy, simply it was done in earlier trials. Of course they know exactly what the dose is.

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