Meghan was 100% channeling Wallis Simpson and Diana in that interview.
From the moment the British press started turning on her, she was ready to cut and run (I think she was still giving it a chance for that brief period around the wedding when it seemed the nation was in love with her and she was making Catherine look dowdy and drab in her frock coats and actually looked like the rising star of the RF. But she was flailing around behind the doors of Nott Cott and in the presence of W&C, all the bullying was happening and she wasn't in control. Not a feeling she likes. The decision will have been easy).
Since the Oprah interview she hasn't said a word publicly about the RF, other than (what she thinks are) cryptic references to her time in the family here and there. Radio silence during Spare, no public statements around QE2's funeral just the appearances, not at Charles's coronation. Nothing other than bland wishes for a speedy recovery for Catherine some time last year which I'm pretty sure will have been instigated by Harry.
She hates - HATES - the lot of them. She's adept at dropping people she no longer wants in her life. She doesn't want any of Harry's family in her life, she doesn't want the British people in her life. She only ever looks forward to her singular goal of fame and money in a small circle in California. Meghan is for Meghan. So much so that the channeling of WS at the time of Oprah was a deliberate "fuck you" to all of them: you expelled Wallis and Diana, but I'm in control here and listen to me dump you. I'm out like these two women, and it's my choice (and I think she said later that after that interview she had nothing more to say about the whole RF debacle). She's on record as knowing exactly how each and every handbag and earring is scrutinized in the press, she knew exactly what she was doing with that dress and that eyeliner, and saying the things she said.
I'm confident that in the Olive Garden house, she will be wondering why Harry cares so much, why he's going back now and begging, telling him to take control of his life just move on. She doesn't realise that he wants to go back because he loved them and they loved him: he wants that back.
I don't think it's obvious to Brits in the UK just how irrelevant the country is to 99.9% of Americans. Meghan has used, dumped and ghosted the entire nation and its monarchy. She got what she wanted, she's moved on.