I can quite imagine wanting a second opinion on someone who seems to be suffering some sort of malaise, especially someone who doesn't know all the business of you and your family and everyone else in the district.
There was talk of a depression of the spirits in the 17th century, but it wasn't really used as a medical term till the mid 19th, century. There were also plenty of dodgy treatments for hysteria in women.
But if you can see the change in someone after being with another person and now how the other person seemed to thrive on travelling, I'd be tempted to recommend the same to the person currently suffering a depression, melancholia, whatever.