The difference between this and No Offence, Holistic, is that our society is massively skewed towards privileging males. The very fact that No Offence is unusual in foregrounding women (and not particularly commenting on, or making plot issues out of, them being women) indicates that there is still a way to go.
I do look forward to the day when I can get angry about a show for its reductive and misandrist portrayal of men, and rant about how it perpetuates stereotypes and maintains the status quo at men's expense, because that will mean that the balance in gender portrayal has changed to such a degree that we have to call out sexism against men, just as we call out sexism against women now.
I haven't seen Coupling so can't comment on it, but I have thought since about Series 2 of Sherlock that Moffat's wife and MIL being on the team has meant that his most self-indulgent urges (not just the sexism but the wildly convoluted and smartarse plots and situations, the smug banter etc) have gone unconstrained. A more distanced senior production team might have been able/willing to rein him in a bit.
Greg Lestrade has never really been brought more to the fore than in Series 1, in contrast to Molly et al; yes, his character has a small role and doesn't develop, but in a sense that's better than the women's roles developing, considering the ways in which they've developed.
Yes, it is interesting to consider Elementary, and to ponder on why the writers/producers on that show came up with a female Watson when Moffat and Gatiss didn't. And of course there's still the question of will we ever see a female Holmes...?
I don't accept the argument that anything is 'just a TV show', any more than I accept the accusation often seen on MN that people are 'overthinking'. Everything is part of the culture and the conversation and can, or should, stand being talked about and thought about.
Cave, at most I'd say Sherlock was weak regarding Irene, yes, but equally she needed him to save her.
Mrs Hudson's character could have been developed in many ways; I maintain that it is interesting to consider why they decided out of all the options available to writers with fertile imaginations to develop her into someone who drives a fast car while on the phone and is into handcuffs.