whereyouleftit when we first meet rory he is wearing his nurse's ID badge and it is dated 1990. yet the action is supposed to be taking place in the present-ish day and he is supposed to have grown up with amy, so should be roughly a similar age to her - and so cannot have been a nurse in 1990.
it has been said that it was just an error in the props department, but some people still suspect it means something.
certainly there is an argument that time in leadworth was messed up even before what we see in Amy's Choice - and yes this can probably be explained away by the crack in time messing everything up but it could point to a longer term arc.
eg - also in eleventh hour, the doctor flies over london which has the London Eye in place, which was only constructed for the millennium. this means that the next explosion must take the tardis back in time for him to crash land at Amelia's house when she is a child...
or else the tardis has landed in a leadworth where time is not what it seems. and that may mean rory and amy are not what they seem, either.
the timeline with melody/mels' regeneration does not add up, either. she regenerated in 1969 and yet still grew up as a peer of rory and amy? again, she probably time-travelled somehow to end up on the right timeline, but how? or again does this point to time still not being quite right among our happy little family?