So let's look at the exact quote by Charlie Kirk you are referring to:
Please fact check the following quote by Charlie Kirk:
Firstly he was discussing four specific women, Michelle Obama, Supreme Court Justice Ketanji Brown Jackson, political commentator Joy Reid, and the late Congresswoman Sheila Jackson Lee, while talking about Diversity, Equity, and Inclusion (DEI) programs.
If we had said [those women] were affirmative action picks, we would have been called racists. Now ... They're coming out and saying 'I'm only here because of affirmative action.' We know. You do not have the brain processing power to be taken really seriously."
Now let's look at the quotes from those women in question:
Sheila Jackson Lee (speaking on the House floor post-SCOTUS ruling): Acknowledging she “may have been admitted on affirmative action” to Yale and the University of Virginia School of Law but emphasizing she graduated on her merits.
Joy Reid (on MSNBC): Stating she got into Harvard “only because of affirmative action.”
Michelle Obama (from her memoir Becoming and related interviews): Describing how her high school counselors doubted her Princeton admission due to low test scores, implying affirmative action helped overcome barriers.
Ketanji Brown Jackson (during her 2022 Senate confirmation hearings): Noting she benefited from diversity initiatives in her career, though she didn’t explicitly tie it to her Harvard admissions.
So three of the four explicitly stated that they were assisted by DEI. The exception is Michelle Obama where it is implied that she benefited from DEI for university entry because of on low test scores .
However it is entirely possible that she may for example have done a stellar interview?