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Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

Ivf anyone starting stimms next week?

523 replies

naty1 · 29/01/2014 21:35

Im starting stimns next week for icsi(dependent on blood test)?
Anyone at the same time want to join.

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suzylee73 · 18/09/2014 21:01

It's a cheaper option and they say it more successful too so it makes sense :)

Egg collection tomorrow, so exciting. I think it's tomorrow for you already though?!

5 is fantastic, lets just hope for at least one good strong fertilised egg, thats all you need. Will be thinking about you :)

Shellster52 · 18/09/2014 21:31

Interesting that it is more successful. Just thinking, Are you going to get any advice about your lining/periods Suzy? I wonder if that is the reason two 5 day blasts failed to implant? Don't mean to add more concern to everything that must be already going through your mind right now, but I just want this to work so badly for us all and I wonder if getting help with that would help your chances before you fork out more dough.

Yep, EC today. It's tomorrow when I get their phone call to tell me how many embryos I have that I want to hurry up and get over with. Last time I had only 1 and it died just before day 5. So even though you are right that one perfect embryo is all I need, I would really like 3 to feel that I have a chance of one making it to day 5.

Crazy as it sounds, I think I would like twins. Even though I have one, and originally only wanted two children, now the fact that this will be my final time is making me want two. I have advised that I want 2 transferred if 2 are available. And I would really like to experience a daughter, so two would up the odds of that happening. I know that all sounds very greedy when I already have one and here I am being so picky now requesting another two and for one to be a girl. Really, with my history, I will be lucky to get one blast, let alone a BFP.

naty1 · 18/09/2014 21:42

I certainly think your situation should be (and luckily is over there) grounds to have 2 put back.
Where it wouldnt be right to get a woman to keep stimming when they cant get many eggs.

Dud you say this is even if they are blasts?

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Shellster52 · 18/09/2014 21:49

Yes, even if they are blasts, I am having two put back.

After 7 failed IVF attempts, I am really wanting to up the odds a bit.

But as I said, will be lucky just to get one to blast.

Guess I will have more of an idea in a few hours when I report back with egg count.

naty1 · 20/09/2014 16:56

How did it go?

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suzylee73 · 20/09/2014 19:33

I'm worried that it might be bad news

naty1 · 20/09/2014 19:49

And me. Fingers crossed for an embi.

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Shellster52 · 20/09/2014 21:04

Was a bit of a disaster.
Something went wrong with the trigger
Last time hubby read instructions and made it up, so I just injected it at 90 degree angle like all the rest of my injections.
This time, hubby was out so I read instructions.
It said to inject at a 45 degree angle.
I did this but it really hurt going in and plunger was hard to press on syringe.
Next day I had hard red sore swollen lump where trigger went in.
Didn't think much of it at the time.
Then only 4 eggs of which only one was mature.
Because trigger went wrong, the eggs were still stuck to follicle wall and those that did come away when flushed were immature.
Really annoyed that this time I followed clinic instructions and it went wrong!
All instructions videos on internet show that same trigger being injected at 90 degree angle - not 45.

That one egg did fertilise.
Having transfer tomorrow morning (day 3)
Will get a call if it dies before hand.

naty1 · 20/09/2014 21:54

Oh no! But that 1 has fertilised though so 1/1 is a good rate.That is odd about the trigger.
I wonder the same about some of the stim injections especially when 1 bled a bit.

Which trigger was it? The same as usual?

Also could this be to do with the menopur?

I had very similar in jan 4/9 mature.
But they said extra trigger would put me at risk of hyper / but guess you could do that next time - trigger is really cheap here. And that it has worked for , i think they said 40 eggs.

I wonder which egg it was that was mature.
I wish they could check on U/S before they do the op to see that they have matured.

Where i had the cancelled cycle i also did 3/4 injections myself where always was OH.

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Shellster52 · 21/09/2014 10:10

It was the definitely Pregnyl trigger. Second time I used it. Last time I injected it straight in and no problems. This time I thoroughly read instructions and injected at 45 degree angle. Never had swollen hard red sore lump like that for days after trigger before. The 45 degree angle meant it didn't get under the skin enough.

Really feel like I should get a discount on next IVF with their incorrect instructions. But of course I can't prove that this was the problem and they will say 'sometimes, not all eggs are mature, blah blah blah'.

Will try to put that out of my mind for now. Just deal with this one embryo and go in for transfer tomorrow. Will chat to clinic about this issue once I have an outcome with this embryo.

suzylee73 · 21/09/2014 20:52

I know it's bad news but it's also great news that you have an embryo :) it's taken a lot of time and money to get this far, I'm excited for you

I can't wait to hear your update tomorrow

Shellster52 · 22/09/2014 00:39

Well unfortunately the update is bad news.
I was about to walk in to my 'pre IVF acupuncutre' appointment when I got a call on my mobile.
I knew it could only be bad news.
The embryo has died.
Tried to then explain to the nurse how the trigger went wrong but she was very quick to cut me off and say that wasn't the issue.
I am 110% certain it was.
Will speak to my Dr when I see her for follow up appointment.
Would like to try again, but the cost is getting a bit much.
Off now to work out my finances.

suzylee73 · 22/09/2014 07:49

Oh I'm so sorry I wish I could make you feel better :(

You can't give up now, you were so close this time. I know you have to draw the line somewhere but if the trigger had been better I feel like you would have had a good chance

naty1 · 22/09/2014 20:11

Devastating.

In my experience they arent too interested in what went wrong (unless i expect you said you forgot completely to take it or took it late)
Its just too easy to go wrong
In the last cycles i have
Taken pill late
Forgotten nasal spray 2hr late once or twice
Wasnt alternating nasal spray

I bet lots of people go wrong on something (without instructions even being wrong)

Then clinic have been wrong about
hydro
Size of follicles as im sure this time some shrank
Lots of immature eggs , possibly follicles too small as about 15mm - should have triggered following day
Missed 1 embi fertilising and 'found it on day 3'
Should have upped my dose earlier last time

Thats without mischarging (just remembered they havent refunded yet. Oh and last tine gonal f delivered instead of menopur

Nhs is quite poor service in general though.

When can you go again?

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Shellster52 · 22/09/2014 22:54

They missed one embryo fertilizing and found it day 3?!?!
You mean they told you there was one less embryo fertilised than there was.
Then on day 3 they told you that you had an extra embryo?

My clinic got the follicle size wrong at my day 6 scan this cycle too.
They said they were all 17-18mm.
I went home upset as they were growing too hard and fast and knew the cycle was over.
I ate junk food and had a big alcoholic drink
Then next scan they were back to 10-11mm!

I am seeing my IVF Dr to schedule next IVF on 1st Oct.
With all IVF's combined, I have had 6 of 14 mature eggs fertilize.
I read a study that showed eating diet of more than 35% protein and less than 40% carbs for 2 months prior to IVF increases blast rate from 30% to 50%.
Well right now with my 6 embryos, I have a 0% blast rate.
I have been trying to eat some protein daily since reading that study, but now I have become a member of 'Calorie King' website and am going to make sure my protein and carb amounts are within this range.
Also going to lose the 6kg I have put on over last two IVF's.
Will have a one or two cycle break (see what Dr says) and work on my IVF protein diet and weight in that time.
I pay less for subsequent IVF's in the same year so it makes sense to try again before this year is out.

Shellster52 · 22/09/2014 22:56

Oh, and I plan on telling my Dr I would like to try just FSH rather than FSH/Menopur combination after reading that Menopur creates dominant follicles.
Will be very interested to see how the FSH alone works for you next cycle since we seem to have the same prob of starting with lots of follies but only a few mature.

naty1 · 23/09/2014 10:12

Yes it will be interestibg.
Though the cancelled cycle i was trying to eat the protein , dont think that worked for me , though it could have been any number of factors.
I have had a but of a gorge on ice cream mainly for the last couple of weeks. And will try to start being a bit healthier from now as i have started the pill today, spray on thurs.
At least the ivfs get cheaper.
Does your clinic close over xmas? Will you have to avoid some dates?
My weight has been quite stable after losing a lot in jun/jul so hopefully that is good

OP posts:
Shellster52 · 24/09/2014 05:05

So you've started the pill and about to start spray.
But when do you actually start stim injections?
Never done the down reg protocol before so I have no idea.

The protein study showed that embryos surviving to blast increased from 30 to 50%.
Did not show that it produces more mature follicles which was your issue last cycle (and my constant issue too!)
I am doing it now to feel I am doing something pro active for next IVF instead of sitting around waiting and aging.
But gorging on ice cream for emotional comfort sounds like a great plan too!

Not sure when my clinic closes over xmas.
That's one question I will ask at my IVF Dr appt on 1st Oct.
I think I should have enough time see this IVF cycle out, then have a two cycle break before starting IVF the following cycle.
I am thinking that would be best physically to allow my body to recover and get a better result.
But emotionally I want to just have a one cycle break and then start IVF the following cycle. I want this ordeal over with.
Will discuss with Dr at appt and make a decision.
Has your clinic ever given you advice how long to wait between cycles?

naty1 · 24/09/2014 10:21

I think it was at least 1 after the bleed coming off the progesterone.
I wont have had any natural bleeds after the cancelled just that noreayerone induced one and the next noresterone one in a in a week during this new cycle.

Yes they did find an extra embi that they hadnt seen fertilise so werent sure if it was abnormal 2pn or 3pn but that could be DD.

I see what you mean about the protein. Sounds like a good plan

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Shellster52 · 24/09/2014 22:45

Okay, so you have an induced bleed in a week and then you start the meds.
So three weeks until egg collection.
That seems to have come around fast, although to you it probably feels like forever.
I am just so curious to hear how you get on with the FSH alone since that is what I plan to do next cycle.

My protein theory went out the window yesterday.
I had one perfect day the day before, but yesterday I had such a bad day at work that I cam home, sat in front of the TV and ate chips.
Not a good start when I can't even do the diet for two days!
Must get back on track today.

naty1 · 25/09/2014 22:16

My TSH is 2 (needs to be under 2.5) so good provided nurse got it right.
It had been 2.4 so has gone down - i upped my dose so it was probably down at 1.5 during last failed ivf.

Under 2 is where it should be according to internet so it is a bit high really but not enough to mess with it again (my DSis was under 1 when her ivfs worked )
Mine has been 4 in jan and maybe 1.5 aug so for me it looks like the higher it is the more pcos i have (diagnosed pcos around 2.1 so they have never got a low result)
Think my solution would be to get my tsh very low but then use much higher stim dose. Which would be normal for my age.
Impossible with such small dose changes to keep my tsh down it is deteriorating rapidly 12.5 mcg to 25 to 32.5 in just a year - and the gps are happy for it to be around 4 no wonder people complain of weight gain etc
dSis is due in next few weeks. Will be before my next treatment Dn was 3 wks early so could be any time.
BIL has been quite insensitive. Complained how difficult it has been with worries then talking about photos of Both their kids together. They have no concept of how hard this is when it doesnt work.

Suzy have you made any decisions yet?

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Shellster52 · 26/09/2014 02:08

My sister is due 13th Oct.
Very hard knowing I will have to go visit her in hospital and fake a smile.
She got pregnant while on the pill so she has absolutely no idea how hard it is for the likes of us.

You really sound like you have an extra stress with this TSH issue.
The Dr's don't seem to be too concerned about it which is probably putting extra stress on you as it makes you then research and worry that you have got it right rather than the Dr's taking that on board for you.
I got my TSH checked amongst other things and will get result when I next go for acupuncture appointment.

I am also keeping detailed log of my food intake and ensuring protein is above 25% and carb below 40% as per study.
Before last IVF, I just generally tried to eat more protein but never kept track.
It's a real eye opener how much little things add up and makes me realise that I was probably not as good in the lead up to last IVF as I thought I was.
Just need to do something to feel like I have hope next time.
14 mature eggs so far and 0 blasts.
Something needs to change.
I hope this diet is it.

naty1 · 26/09/2014 09:40

I know what you mean my usual diet is probably 90% carb/fat if not more im not a bit protein eater.
I did the protein drinks last time as even milk is 50% carb.
I think my dsis is about 11th oct (though shes abroad so no visiting baby)
It would have been so different we could have had cousins 1mth apart.

OP posts:
Shellster52 · 29/09/2014 12:17

Does that make things easier with your DSis abroad?
Mine is just around the corner so no getting out of this one.
I am really trying to work hard on my attitude before the next IVF.
But I am sure visiting her and with family all talking about her and gooing and gahhing over baby, I will be feeling quite down in the dumps.

I'm not big on protein either.

Getting quite annoyed at myself with each day that passes putting me closer to my next IVF and I still can't help but choose carby foods.
I am vegetarian so it's a real chore swallowing dead fish daily and much easier to talk myself into something else!

naty1 · 29/09/2014 12:57

Not a big meat eater. And DH wont eat much fish. Most protein i have carbs with like rice, bread, pasta so still eat more carbs than protein.

Did you say if you tried protein shakes?

Yes think it will be bit easier with her abroad. As not dealing with it every day. May have to cut back talking to DM though if she keeps going on about baby. I was just about giving birth with DD when DSis got pg with DN so she luckily didnt have to go through the same issues. Though, she had never been sure she wanted kids so not sure how upset she would have been if it didnt work, even with this baby i dont get the feeling she would have been as upset as i have been.

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