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Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

Assisted conception after recurrent miscarriage

1000 replies

duggs1976 · 22/05/2013 19:49

Hey super ovulators and those struggling with infertility after miscarriage this is where we are! Come on over ...

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Pebbles73 · 19/07/2013 17:52

That sounds great Sue, so glad it all went well. Can't believe how cheap the intralipids are!!

Pebbles73 · 19/07/2013 17:54

Also meant to say hope you get some answers tomorrow Brown, let us know how you get on.

Mel3062 · 19/07/2013 18:37

Hi ladies not sure why I've not been able to get updates :/ still here now. Sue best of luck and pebbles. Brown let us know what happens!
Going Mexico fri but if weather continues I could've stayed home but we def need a break.
Waves to all x

Mel3062 · 19/07/2013 18:41

Sue wow to your appointment!!

Buzzybee123 · 19/07/2013 23:24

brown any news on your scan today

sue that sounds like an amazing appointment, interesting about AMH being dumped, I think that test has caused women no end of misery. Onwards and upwards for you

mel at least in Mexico you'll have nice beaches :)

brownstag · 20/07/2013 08:21

sue, that's great news! And hooray for being able to forget about rubbish AMH!
I had my scan at 2.30 which showed one large follicle within one ovary, although this morning I had a temperature rise, so it was obviously released yesterday.
Everything looked normal as far as retained products go so that's good. I tried not to be too obvious about looking for what else was going on, but she said I was mid-cycle and I could see a lining of 10mm at day 15. Is that good? I only know what it should be at trigger injection. I was a bit disappointed that there was only one egg on 7.5mg letrozole, but I've now realised I took agnus castus at the same time! Also I took it days 3-7, not 2-6.
They left a message on my phone about the blood test results as I had gone to bed (apparently they are never meant to leave messages but I said they could) and all it said was you're not pregnant. Errr, well I knew that, but what was the actual result? Was there any hCG at all? Off on hol today so don't know if I'll have time to ring them.
Waves to all and have a lovely time in Mexico Mel.
Just one question that occurred to me. If you release two eggs, you presumably have two corpus luteums (lutea?) producing progesterone. If you then conceive with one egg, presumably one continues to produce it? How does the body know which one, or do they both do so?

duggs1976 · 20/07/2013 19:02

That lining size is fine brown I know they want over 9mm to trigger so you are about right. Smile

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Pebbles73 · 23/07/2013 13:51

A bit late but have a fab holiday Mel,

Brown lining sounds good, good luck.

Still trying to decide about having this scratch done, so much more convenient to start ivf now but want to do everything possible to give this a chance. Just phoned up and had a chat to Mr Gafar, was quite surprised how easy it is to speak to him. He basically said he is not sure how much of a difference it makes but they like to offer it to people with failed ivf/implantation. Said I had read an article in the times which says can improve chances by nearly 50% and as he punted out you have to be careful what you read in the press. He suggested I go in for a scan at beggining if month and if bleeding not too heavy he can do the scratch now in the same month as treatment rather than waiting but I read on one study that it made implantation less likely if done in same month.[confused{

duggs1976 · 24/07/2013 06:28

I've just read ideal time is 2 weeks before egg transfer... So presuming ET is day 12 then work back from there ?

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Pebbles73 · 24/07/2013 08:57

That's strange as everything I have read has advised previous cycle to stimulation. Where did you read that Duggs as that would be great as could start ivf this cycle in just over a week!

duggs1976 · 24/07/2013 09:34

Just googled "ideal time for endometrial scratch" ..lots of links came up all saying between day 19 and 25 of cycle before or 14 days before egg transfer which ends up pretty much the same thing ! Have a search!

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BellyD · 24/07/2013 15:23

Hi everyone, sorry for going dark, but we have been away for a much needed and lovely hol.

Sue your appointment with Dr N sounds really positive - he does come across as more caring than some of the others, don't you think? What time were you there on Friday? We were there for our follow up appointment at lunchtime that day. I hope that you feel good about having a plan. Dr N felt that there was too much fragmentation on our embryos so we are going to try DHEA and then cycle again in October. In the meantime we are going to have a monitored natural cycle next month, followed by letrozole cycles for the next couple of months until October. Onwards and upwards..

Mel and Brown hope you have/are having great holidays.

Ari thinking of you. Wondering if you had a lovely holiday and that you are feeling as well as can be expected.

Duggs thanks for the weblinks recently - am going to check them out when I finish writing this.

Lemon hope your DS is fine now and that the breast feeding is getting easier.

Buzzy how are things with you?

Pebbles glad Mr Gafar is easy to get hold of. Don't know much about scratch's I'm afraid. There is something called embryo glue you can use too, but don't know a great deal about that either! Not very helpful, sorry Confused. Hope your dad is getting on ok. Are you going to cycle over your 40th or afterwards?

I was going to the theatre with my sister last night near where the Royal baby was in hosp, and went round to have a sneaky peak to see what was going on. We had to leave to go to the show so missed them leaving by 5 mins, although got a glimpse of them driving past us. Was dreading the birth as so near my due date for No. 6 but am actually really happy for them. I often feel like this with friends etc, dread the birth but then find it is fine because it is not my baby. Does anyone else feel like this?

Sorry for the long post!

lemonsherbet · 24/07/2013 16:31

belly your appointment sounds like progress. I would guess that DNA fragmentation may be a cause of some of your other miscarriages? It sounds like they are looking after you.

Again I do not know anything about endometrial scratch. I think Ari had it in greece with her last cycle. Though I could be making that up.

Breastfeeding having good and bad days but hopfully getting there.

Waves to all.

Mel3062 · 24/07/2013 16:38

Thanks ladies, I'm not able to get an update for some reason so have to do a search everytime!
Well we go fri am. Did test today as af due mon but bfn :( now I don't know if to keep testing til fri. Just worried that ill get a bfp over there and won't have my steroids or clexane! Though if bfn fri I think that's conclusive!
waves to all and hope were all moving forward abit x

duggs1976 · 24/07/2013 18:58

Belly did dr n say if he though your man might be a DNA fragmentation issue like mine was? Because if you have until October you can address his problem in 90 days if no underlaying causes like hidden infections and that just takes another month of strong anti bs? Sorry wasn't sure if he suspected you or him?

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Pebbles73 · 24/07/2013 19:49

Oh god I think I have been an idiot and got all confused re this scratch thing!! I have been reading it is needing to wait a month to start ivf rather than just having the scratch in the previous cycle! Can I use the excuse if stress from the situation with my Dad?! Blush Thanks Duggs. Smile
So I have scratch booked for tomorrow on day 26 with Mr Gafar and then now assume I will start my short protocol when af starts, all that worrying for nothing!

On the plus side my Dad hasn't been doing too badly last few days and we have found him a care home that specialises in dementia. Just hope he will get used to it and settle in now, don't think it will be easy as he wants to go home.

Good you have a plan in place Belly

Enjoy your hols Mel and is still early for a bfp!

Mel3062 · 24/07/2013 21:01

Thanks pebbles.good luck with scratch. Glad things are going ok with your dad. My worst nightmare would be to get bfp when away and have no injections or pred, I really don't know what to do about that!

duggs1976 · 25/07/2013 07:08

Ok pebbles ! Can I ask how much is this scratch with mr Gafar? Wonder I I should have one?

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duggs1976 · 25/07/2013 07:09

Oh and mel where r u off to ? You might be ok?

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Mel3062 · 25/07/2013 07:27

Mexico, I'm going to ask doc to give me a note and take them just in case I think, it may seem daft but I'd rather have them in case rather than not as it would be bad enough without hcg and intralipids!

joycep · 25/07/2013 18:16

Hi ladies, i hope you don?t mind me diving in...i?ve done it on and off over the years(!). I was just wondering whether anyone knows why some people are given IVIG and others are given intrallipds? After 3yrs of ttc and one natural m/c behind me, I had my first ivf in Jan at the Argc which resulted in a twin pregnancy. Sadly i lost them both at 10wks. This was a chromosome issue. But I have high nk cells and I was on IVIG and steroids etc. I plan to go again in Sept and I really don?t want to have ivig again. This is partly because of what it is but also the sheer cost. It left a very bitter taste that we spent so much money getting to 10wks and it ending and I wasn?t quite convinced i actually needed this £1500 a go treatment when many people with high nk cells normally are just on pred.
So does anybody understand why some are put on intrallipids and others on ivig and does it actually make a difference? Am really curious to know.
sue - read with sheer glee that ZW now don?t look at amh. They were always really keen on that as an indication of fertility. Mine was about 3 over a year ago so i expect it is much less now. But every time i think about it , this panic runs through me!

duggs1976 · 25/07/2013 18:40

Hi Joycep, sorry to hear of your losses. From what I understand some people don't respond to intrallipids - dr Gorgy actually does the test as part of his investigations as to how both intrallipids and Ivig affect your killer cells. This sorts out who needs Ivig as intrallipids not effective enough. I'm not sure if ARGC just throw the book at every patient and go for the stronger one rather than fanny-ing about? From what I know of them that might be the reason why it's a blanket? If your issue was chromosomal for sure then the Ivig worked but you could ask dr g (or another immune dr who looks at this area)!to just test that aspect so at least you'd know. Test is £400 odd with dr g and £150 for consultation so. I guess an investment up front that could potentially save u longer term if answer is what you hope. If it isn't then at least u know you have no choice. Best of luck. R u cycling with ARGC again?

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joycep · 25/07/2013 21:13

Thanks so much Duggs - that's all really helpful to know. I had no idea that you could get tested. It would be a great help to know so at least if ivig is the only option at least I would know. I am going back to the argc for one last throw of the dice!

Pebbles73 · 25/07/2013 22:30

The scratch was £150 Duggs, just like a smear and the scratching just feels crampy. All over in about five mins, fingers crossed it helps, just need to wait for af in about five days now and have baseline scan and start stimming.
Was it beginning of August you start?

Welcome to the thread Joy and so sorry to hear what you have been through.

Mel3062 · 26/07/2013 04:19

I didn't know that either duggs I may ask to be tested too when I do go see him after all it's a lot of money to waste if it doesn't work for you!!
Pebbles fingers crossed for you! I think/ hope I had a scratch done when I had my hysteo.
Ill try keep looking when I'm away good luck ladies x

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