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Infertility

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Assisted conception after recurrent miscarriage

1000 replies

duggs1976 · 22/05/2013 19:49

Hey super ovulators and those struggling with infertility after miscarriage this is where we are! Come on over ...

OP posts:
BellyD · 12/06/2013 14:10

Ari they like at least 5 to do CGH, I think because there is a risk of damaging the embryos during the screening so they like to have quite a few to spare. Duggs I can't remember how many you had when you did your CGH? Ideally we would have liked to have tested them to avoid a chromosonal mc but at this point we are just grateful for anything. We could freeze these and undergo another cycle with the hope of then having 5 but Dr N is reluctant to risk that.

Can totally understand the only child angst. I'd always imagined having at least three, now I would chew my own arm off to have just one - but wouldn't want them to be an oc, which will be our reality if we ever get that far.

brownstag · 12/06/2013 14:26

Meant to say excellent news Belly too. I find so many Bs confusing, sorry!

suemays · 12/06/2013 17:30

ari hoping its not an eptopic and a straight forward loss (if you know what I mean).

Well done to buzzy and belly both have a long way to go but every step is a massive success for us ladies.

I am another one whose heart breaks at the thought of my dd being an only child. Nearly every day she brings home a drawing of her and baby scarlet in the sky. I think as she is the only one without a sibling in her class she feels lonely when the others talk about theirs. It's hard not to get upset with her!

Mel3062 · 12/06/2013 18:02

Super news belly
Ari I'm glad you're having the scan, if you don't ask you don't get ;)
Don't know if to have nhs op too, I'd be awake but they do perform a biopsy which I've not had done or do I get nk cells tested with prof q, umm will nhs be able to tell I've had it done before with the cuts they did?
Yes I'll go mr gorgy if results are normal, if not i may leave it and just see if hysteo has helped. I've emailed mr braver man ( american guru) and he seems to think my uterus was part of the prob.
Gransol I know what you mean about humira hopefully it has a cumulative effect.

buzzybee123 · 12/06/2013 20:17

ari I am so sorry, its such a worrying time for you, don't worry about anything else, do you think your husband is worried about the affect this all has you on?? Is DD his, I too did think that donor embryo might be your next step, it would be cheaper and have a higher success rate.

Glad you have an appointment with EPAU

duggs good luck with your appointment

bellyd yay to 3 the musketeers

gransol · 12/06/2013 20:39

Have decided to take two more injections and hope it brings it down that little bit further

Glad scan went well buzzy

duggs1976 · 13/06/2013 05:31

Fab news belly Grin yes we had 4 embryos left at day 2 which were all tested. They all looked ok to the embryologist. 3 were ok 1 was very abnormal. However I wouldn't worry about the CGH/PDG test as i later discovered if the sperm is the issue then unless major chromosome missing or adding then the sperm DNA defect won't get picked up at a day 2 or 3 test as is too early. So really it is a test on your eggs, but they like to have more to test because with 3 they'll shove them back in anyway and freeze the rest most likely so little to gain from testing. I guess if you've had a big history of chromosomal issues like kittens it could help but she didn't have it and now she has her little man!
Saw hammersmith dr should start IVF cycle mid July.

OP posts:
BellyD · 13/06/2013 14:18

Duggs thanks for the info. Glad you have got a starting point for your ivf. It will be good to get going won't it?

2 embies survived the night and are now 2 cell (would be better if they were 4 cell by now am I right?) One is average quality - grade 2/3 and the other grade 3. They are going to pop them back in tomorrow afternoon and then we will see. Feel glad to have got this far tbh. Progesterone shots in your bum are no laughing matter mind you - are you having those, Ari omg I can barely walk! Not complaining though. Needs must.

Arianrhod · 13/06/2013 14:52

Crossing fingers for your little embies belly! No, I avoided the progesterone shots like the plague when I heard how bloomin' painful they were from the FF ladies. I use cyclogest, 3 times a day at the moment but you know, to avoid the shots I'd take them 20 times a day if I had to! :)

duggs did your Hammersmith doc tell you what protocol, is it anything different to before?

mel Serum follow Dr Braverman's protocol, he's supposed to be something of an immunological guru I think.

buzzy Yes, I'm sure OH is worried about the effect on me, bless him, but I suspect it's more than that. No, DD isn't his, unfortunately, and I really don't know how he feels about having a baby that isn't genetically his, he hasn't (and won't, no doubt) said. Hasn't commented at all, actually. Are you feeling a bit more positive after your fab scan? :)

Well, I wish I could report something from my scan this morning but unfortunately it was inconclusive. They could see a what-could-be/become a pregnancy sac but it's very small, less than 1cm. I said well surely this cannot be viable, being so small, and their answer was they can't rule it out. Really?! But when pushed, the staff nurse did say it was very unlikely. I should say! They couldn't see anything outside of the uterus, no masses, lumps or fluid - but said that because it's still very early (I'm technically 6w5d) they may not see anything even if it is ectopic anyway. They've said not to bother with any more blood tests, but to go back for another scan in one week, next Thu, to see what's changed, if anything. And to just watch out for any changes, pain etc in the meantime. The small amount of bleeding I had yesterday has stopped, and they couldn't tell where that may have come from either.

Basically they don't know, nobody knows, but whatever it is my body is hanging on to it for dear life. It may be ectopic, it may not - but we don't know.

My cr@ppy body can't do anything right!!!

/waves to everyone, choccy, are you out there?? :)

buzzybee123 · 13/06/2013 15:33

ari sorry this is dragging on for you, big hugs

Mel3062 · 13/06/2013 17:06

Aw ari sorry you're going through all this :(
Louise said mr s does the hla/dqa for £100 but there's no evidence and hel talk to me about it Saturday!

Arianrhod · 13/06/2013 18:53

If you want it mel, then stick to your guns and ask for it. He may not believe it makes much difference but boy it can do. I'm walking evidence of that!

suemays · 13/06/2013 20:49

ari could you potentially have one ectopic and then a normal uterine pregnancy? Maybe its just a slow grower? Sounds like you may still have a chance.

belly good that 2 have survived until today. I have no idea about the cell size but at least there is some hope that at least one will work. I have heard of ladies having babies with grade 3 so stay positive!

duggs glad you are moving on with next ivf round. I thought you had some frosties though from the first go???

mel I would stick to your guns too! You don't get anywhere without pushing it seems!

Well I am busy mentalling and symptom spotting on the 2ww. Have had sore boobs today but am aware its prob from the cyclogest I am taking. I have also been getting tingly teeth???! Anyone had any thing like this on cyclogest when not pregnant? I seriously don't think I am preg as not due to test for another week yet - only 6dpo today.

suemays · 13/06/2013 20:57

ari just googled it and it can happen. It's called heterotopic pregnancy.
community.babycenter.com/post/a6829895/concurrent_ectopic_intrauterine_pregnancy

miscarriage.about.com/od/miscarriagecauses/p/heterotopic-pregnancy.htm

BellyD · 13/06/2013 22:14

Did you guys see this article www.telegraph.co.uk/journalists/laura-donnelly/10113451/New-tests-to-check-on-pregnancy-progress.html not sure if it's a good thing for ladies like us or whether it would just add to the mentalling.

Mel3062 · 14/06/2013 05:03

I think I'll have it done and then it's done and its cheaper than mr gorgy. Would mr gorgy interpret results if needed even if I didn't have the test with him?
Mr braver man said "Yes that is correct an defect in the uterine cavity can also be responsible for these losses. A full HLA analysis not just DQalpha would also help to try and elucidate the problem."
I'm cross though as still no results and rmc lady said shed chase them up Monday so now I don't know if to cancel mr s tomorrow as he wanted me to go with results for next steps argh! I don't know what to do as I'd like to go for this test but don't want to end up going again when I get results!
Does he charge cancellation fee?

duggs1976 · 14/06/2013 06:54

Mel i would def cancel dr s (feign illness if necessary). You are going to be paying for advice based on no results and having a further test for an area he "doesn't have experience in" as he doesn't "believe in" which is contrary to many others. In my experience he will give you if's and buts and be VERY positive which he always is which is nice for a bit but pretty pointless if you've got no further! Hope they arrive soon. Have you decided to stay with dr s over the other options then?

OP posts:
Mel3062 · 14/06/2013 07:03

Thanks duggs or shall I just email Cheryl and just say results aren't back or will illness be better?
It does seem bizarre paying a couple of hundred if not more if I haven't got the results!
Ill stay with dr s if results show chromosome or chicken pox issue as then it couldn't be helped. If normal I'm hoping the hysteo has helped and will def get hla/dqa test done so alots riding on the results really! Frustrating!!

Mel3062 · 14/06/2013 07:20

Ill be cross if I cancel appt then rmc lady emails me it at 8.00 tonight! She's emailed me at that time before!

Arianrhod · 14/06/2013 09:43

Crikey, thanks sue ... I hope it's not that, how much more complicated can this get! :) Thanks for the links, they made interesting reading. I've never had tingly teeth either pg or not, so can't help you on that one, but I know lots of women have all kinds of odd symptoms so maybe that could be one for you?

mel Can you not ring your RMC lady?

suemays · 14/06/2013 10:02

ari I have never heard of it either but I might explain why your hcg levels are going up and down and why the pregnancy sac is small. There is still a chance it might keep growing.

mel I would be honest and tell them the results are not in. I have had to cancel appts and nlc were fine with it. I am still convinced I lost a baby last year due to chicken pox even though the blood test showed I had immunity. My dd had a bad case of it and then I came up with a weird rash and a cold, seems too much of a coincidence to me!

Mel3062 · 14/06/2013 10:38

Thanks sue the rmc lady is on call though wasn't in clinic yest but should be able to get emails. Her secretary's on hol! I think I'll have to cancel there's no point otherwise, ill give it til later on and just be honest I think! X

Mel3062 · 14/06/2013 12:38

Rmc lady emailed:- Have just phoned the lab - unfortunately the sample failed to grow in culture so we will not get a result. This happens in over half the samples we send as there is often only a small amount of tissue. Unfortunately it doesn't help us understand why your last pregnancy failed
Helpful :(

Pebbles73 · 14/06/2013 14:08

Sorry to hear you are stuck in limbo Ari you must be feeling mightily fed up with it all!! Sounds like it is trying to hang in there.....

What a bugger Mel , are you still going to see Mr S?

Arianrhod · 14/06/2013 14:30

Oh no mel, what a let-down after all that waiting and chasing!! Will you still see Mr S?

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