Meet the Other Phone. Only the apps you allow.

Meet the Other Phone.
Only the apps you allow.

Buy now

Please or to access all these features

Covid

Mumsnet doesn't verify the qualifications of users. If you have medical concerns, please consult a healthcare professional.

Anybody been invited and declined the jab?

716 replies

Devlesko · 19/04/2021 14:03

Beginning to think I did the right thing now.
Anybody else?

OP posts:
Terracotta9 · 20/04/2021 12:48

The regulators class the mRNA vaccines as gene therapy. You may argue that they are wrong to do so because the term is too scary for the masses to cope with, but it doesn’t change the fact that this is the currently terminology used by the regulators.

Also, literally no one here has brought up altering DNA on this thread except you.

oldegg123 · 20/04/2021 12:57

@Terracotta9

The regulators class the mRNA vaccines as gene therapy. You may argue that they are wrong to do so because the term is too scary for the masses to cope with, but it doesn’t change the fact that this is the currently terminology used by the regulators.

Also, literally no one here has brought up altering DNA on this thread except you.

??

My post regarding COVID vaccines not altering your DNA was a direct response to the PP copied below, you then jumped on my response.

I'm not an anti-vaxxer. Always have my vaccines and my kids are fully vaccinated.

But the covid 'vaccines' are experimental gene therapy, not traditional vaccines. They are technically still in trial stage (not finished until 2023) and are still unlicensed - they were rushed through and given emergency approval. The long-term effects are simply unknown. For people who are under 55 or so it's madness to take the risk of this experimental medical procedure when the risk of dying from or being seriously ill with Covid is so incredibly low.

Terracotta9 · 20/04/2021 13:01

Yes, you responded to that poster who (correctly) stated that the vaccines are gene therapy, but who didn’t mention anything about altering DNA.

PhilCornwall1 · 20/04/2021 13:03

I have read of people who are getting texts and phone calls because they have not booked an appointment.

If my GP surgery is anything to go by, they are enjoying sending the text messages.

CorianderBee · 20/04/2021 13:11

No had both of mine now, glad I did. First one felt quite ill but second one I was fine. All done now.

MaxNormal · 20/04/2021 13:11

@TheVanguardSix I am so sorry to hear that.

Roonerspismed · 20/04/2021 13:21

But does gene therapy always mean altering DNA?

And please remember the words “highly unlikely” to alter DNA have been used.

I haven’t been offered any vaccine yet but in my view the long term effects of mRNA vaccines are unknown even if such risks are remote.

Parker231 · 20/04/2021 13:22

It is not a new vaccine.

Researchers have been studying and working with mRNA vaccines for decades. Interest has grown in these vaccines because they can be developed in a laboratory using readily available materials. This means the process can be standardized and scaled up, making vaccine development faster than traditional methods of making vaccines.

mRNA vaccines have been studied before for flu, Zika and rabies. As soon as the necessary information about the virus that causes COVID-19 was available, scientists began designing the mRNA instructions for cells to build the unique spike protein into an mRNA vaccine.

Parker231 · 20/04/2021 13:25

I thought the ‘it changed your DNA’ had been covered already. mRNA never enters the nucleus of the cell, which is where our DNA is kept. It does not change your DNA.

Terracotta9 · 20/04/2021 13:26

But does gene therapy always mean altering DNA?

No.

According to the FDA:

Human gene therapy seeks to modify or manipulate the expression of a gene or to alter the biological properties of living cells for therapeutic use

“Altering biological properties of living cells for therapeutic use” describes the mRNA covid vaccines, the alteration is making the cells generate the spike protein

Terracotta9 · 20/04/2021 13:53

It is not a new vaccine

The covid vaccines are the first mRNA vaccines licensed for human use.

The covid vaccines (and 2 Ebola vaccines licensed recently) are the first viral vector vaccines licensed for human use.

BuggerBognor · 20/04/2021 13:57

This reply has been withdrawn

Message from MNHQ: This post has been withdrawn

UnderTheSkyInsideTheSea · 20/04/2021 14:03

Yet there are no increases in the usual death rate confused In fact a few months ago it was lower than average.

This is dangerous misinformation, @Devlesko. Why are you spreading lies? Is it deliberate, or are you just believing nonsense memes on social media? Hmm

Parker231 · 20/04/2021 14:15

@Devlesko. Not sure where your information is coming from?
In the 52 weeks to Christmas Day 2020 , 604,045 deaths were registered in England and Wales.
If you look at civilian deaths, the only other year in which more than 600,000 people died in England and Wales was 1918, when the final year of World War One coincided with the Spanish Flu.

FloconDeNeige · 20/04/2021 14:26

The regulators class the mRNA vaccines as gene therapy. You may argue that they are wrong to do so because the term is too scary for the masses to cope with, but it doesn’t change the fact that this is the currently terminology used by the regulators.

This is patently untrue. Neither the FDA nor EMA consider RNA vaccines as gene therapy, for the simple reason that they’re NOT.

RNA is an inherently unstable molecule, which is rapidly degraded and in the case of the vaccines, it never enters the nucleus of the cell (where DNA is housed). Ergo, it cannot alter DNA.

Stop peddling unscientific and dangerous rubbish. What the fuck is wrong with you? Do you go around licking products on supermarket shelves as well?

Terracotta9 · 20/04/2021 14:36

Read the fucking thread, please.

Ergo, it cannot alter DNA

Something doesn’t have to alter DNA to be classed as gene therapy. For the THIRD time I will post the FDA definition of gene therapy:

Human gene therapy seeks to modify or manipulate the expression of a gene or to alter the biological properties of living cells for therapeutic use

This describes what the mRNA vaccines are doing - they “alter the biological properties of living cells for therapeutic use”, by getting them to make the spike proteins

Both Moderna and BioNTech acknowledge in their SEC filings that US and EU regulators consider mRNA technology to be gene therapy.

grapewine · 20/04/2021 14:59

civic duty to have a vaccine... give over.

FloconDeNeige · 20/04/2021 15:02

@Terracotta9
How about you quote the FDA definition in full, eh? You forgot this bit;

*Gene therapy is a technique that modifies a person’s genes to treat or cure disease. Gene therapies can work by several mechanisms:

Replacing a disease-causing gene with a healthy copy of the gene

Inactivating a disease-causing gene that is not functioning properly

Introducing a new or modified gene into the body to help treat a disease*

RNA vaccines do not modify DNA and are therefore not gene therapy

The regulators DO NOT consider them to be either.

www.google.co.uk/amp/s/www.forbes.com/sites/brucelee/2021/03/17/covid-19-mrna-vaccines-are-not-gene-therapy-as-some-are-claiming/amp/

Parker231 · 20/04/2021 15:04

Saying that having the vaccination is your civic duty is overkill although I’m all for everyone who medically can having the vaccine.
I’ve had one vaccine so far. Having the second AZ next month.

MarshaBradyo · 20/04/2021 15:08

Probably better to avoid terms like civic duty as it makes many dig their heels in even more.

Eg A pp mentioned declining partly in protest earlier.

Parker231 · 20/04/2021 15:10

Anyone who declines as a protest is a total idiot!

Terracotta9 · 20/04/2021 15:10

@FloconDeNeige

Moderna’s own SEC filing acknowledges that:

Currently, mRNA is considered a gene therapy product by the FDA.

And from BioNTech’s SEC filing:

Although we expect to submit BLAs for our mRNA-based product candidates in the United States, and in the European Union, mRNA therapies have been classified as gene therapy medicinal products, other jurisdictions may consider our mRNA-based product candidates to be new drugs, not biologics or gene therapy medicinal products, and require different marketing applications.

So tell me, why are the vaccine companies saying to their shareholders that the US and EU regulators consider mRNA technologies to be gene therapy?

Is it just for fun?

ConstantlyChanging · 20/04/2021 15:22

But I do feel fairly judgemental about people refusing the jab, getting ill, and taking up NHS resources for something completely preventable.

A huge amount of what the NHS deals with is ‘completely preventable’ though. Do you also feel judgmental about all treatment for people who are overweight (most of the population), all smokers, all those who injured themselves doing something they didn’t need to when they could have stayed home or done a safer alternative (horse riding, skiing, jogging on an uneven surface... ), all those in car accidents on non essential journeys, all those who got bitten by a dog they didn’t need to have or at the park they didn’t need to go to? Or is the NHS literally only to be used for viruses you caught despite your best effort?

tonystarksrighthand · 20/04/2021 15:24

Yes I did. I politely declined.

ConstantlyChanging · 20/04/2021 15:25

I had my first but have declined my second for now (AZ). We don’t know enough about these vaccines in my opinion. I don’t think our government is right and all the others are wrong.