[quote Motorina]@Haffiana, the data from the original Pfizer trial, as published in the NEJM, did show immunity 'switching on' at around the 14 day mark. This was also the view of the JCVI.
I appreciate that the pre-print that you have linked to suggests something different. I have yet to find any further information in the public domain about this analysis than this, which is in effect an abstract. It is, however, based on a different data set and so it is unremarkable that it shows a different result.
If you're going to take digs at other posters here then you might want to make sure that they are accurate first.[/quote]
@Motorina Yes, the data showed that immunity 'switched on' at 14 days.
It did NOT show that it went to 90% at that point, which is the point of
a/ the actual preprint
b/ my post.
You are making a strawman argument over something I have not said or even inferred and also claiming that this switching on was the 'view' of the JCVI. It wasn't their 'view', it was shown very clearly in the data.
I am not having a 'dig' at anyone, but plenty of people were misunderstanding this and looking at one line on one graph of the original trial data, despite others of us who actually read the data pointing out that this was not what was shown. People still repeat this incorrect deduction in threads on here to the present.
When the early Israel data was released there was some astonishment that it did not show this -fictitious- 90% efficacy at 14 days.
This is what the preprint is reanalysing - the point at which the efficacy is actually 90%.
What has now been derived from the Israeli data according to this preprint is that 90% is achieved at 21 days - which is more or less identical with what the original Pfizer data showed.
OK? So are we back now to what the preprint and Haffiana actually said?
The Guardian HOWEVER, and as quoted by MRex has stated this preprint to say: "One Pfizer/BioNTech jab gives ‘90% immunity’ from Covid after 21 days"
I posted to point out that it says nothing of the sort. It makes no reference to 90% immunity after 21 days after 1 jab. It refers to 90% efficacy AT or BY 21 days.