@TheSunIsStillShining specifically for Crohn’s and Colitis I imagine that would be incredibly hard data to collate. Flaring isn’t a yes no question (and I say this as someone who has had Crohn’s for 25 years), for most patients it isn’t a switch between two states but a spectrum, how would you quantify it? Disease scores are good for tracking the same patient over time for a Crohn’s drug trial, but not for a short term snapshot for a non Crohn’s drug.
I for example continuously bleed from my small intestine (I don’t have a large intestine) and empty my pouch between 10 and 20 times a day. For some people that would be a score off the charts, for me it’s totally normal and I’m not even currently taking anything as I reserve that for when it gets worse. If I had been in the vaccine trial, how would my Crohn’s score be reported?