A vaccine is very likely to happen

[FreierFall]

I've worked in big Pharma for years. I am 99% sure an effective vaccine will be produced this year. It's gonna happen, have faith in scientists. They will be working their butt off....

"Pfizer CEO Albert Bourla told The Wall Street Journal the company's COVID-19 vaccine could be ready for emergency distribution by the fall. The company could further be ready for a broader rollout by the end of the year, he added"

God, thank god you reminded us about testing regimes and thalidomide.. the scientific and pharmas might have clean forgotten 🙄

Yep, it will come out when enough people have died, around about the 53k mark.
We'll all be so desperate to get it, whatever it contains.

I know we all really want there to be a vaccine, but just a reminder there's no vaccine for AIDS yet, 40 years on...

HIV is a retrovirus, which makes it extremely difficult to find a suitable vaccination. SARS COV 19 is not.

Not sure ds will be able to have any vaccine as he is allergic to something (they think it is a preservative) we just don't know what.
He cant have the flu vaccine as it is a nasal spray for him so might have the unknown in. I guess we just do what we did with his asthma drugs first and have it in a hospital environment where he can be monitored. Doubt that would be thier first priority to arrange tho.

@ErrolTheDragon animal testing is largely about safety not whether it will work in humans

"Pre-Clinical Stage
Pre-clinical studies use tissue-culture or cell-culture systems and animal testing to assess the safety of the candidate vaccine and its immunogenicity, or ability to provoke an immune response. Animal subjects may include mice and monkeys. These studies give researchers an idea of the cellular responses they might expect in humans. They may also suggest a safe starting dose for the next phase of research as well as a safe method of administering the vaccine"

OP thank-you for providing a bit of hope.

Yes there are the doom and gloomers.
Yes it's scary getting a new vaccine.
But you know what, we can't live like this for months never mind years.
Children need education
Adults need to work.
Retired need to get out and do stuff.

We all need company, we all need a social life.

I'd have it.
Yes it is probably riskier than a vaccine that has been around for years, but it's not like we are certain covid itself has no long term effects. I would rather trust my covid immunity to human scientists who have done their best to make it safe than to Mother Nature who is completely indifferent to my wellbeing!

I agree OP, There is a lot of money to be made from this vaccine so they are competing to get an effective one out asap.

I understand that scientists were working on vaccines for other corona viruses and the work was shelved since they didn't spread as expected, some work will now take off where the previous research ended.
The top scientists are working and sharing research so it will be much quicker than usual. Usually scientists work separately and sharing now on an unprecedented scale.
I hoping for the Autumn

Read in a BBC article that a team in oxford had already been working on a SARS virus for some time, and the lead scientist gave an 80% rate of it being successful. They've already started the process if mass producing the vaccine, and I believe she said September is when she expects it to roll out, providing it is effective.

@Springcatkin That must be so tough, but this is exactly why mass vaccination is so important for any illness which spreads like this. The more of us who can have it that do have it, then the less is will spread within the wider population, so the risk of exposure to those who can't is significantly reduced.

And I know this has built on work already carried out for SARS which is why it is so quick.
I always knew those talking about waiting years for a vaccine did not know what they were talking about.

Assuming this occurs, I'm sure OP could give some insight into how this could be distributed.

I heard the Oxford Professor on Andrew Marr last week saying that the vaccine they are testing comprises ingredients rehashed from products already safely checked so not a concern with this vaccine.

@springcatkin
Can he not have the flu injection instead?
My son can't have the spray so has the injection. He is 5.

The biggest problem with the testing is that with lockdown still going on they’re going to struggle to get enough cases of the virus in the control groups to prove efficacy. Not a lot you can do about that, just recruit an awful lot of testers and be patient.

Justajot Wed 29-Apr-20 15:02:28
"I am particularly concerned that it might be developed in the US with Trump's insanity reigning."

If Trump is involved then we will be injecting bleach....lol

This is a 'joke' by the way. I am pro vaccine and will take it when it is available. I have taken many vaccines, the usual childhood ones, holiday vaccines and also if the last few years seasonal flu vaccines.

Oh my god you already know sue and Bob the Mumsnet dementors know better than the world's leading scientists. I mean just look at the Mumsnet facts. Hilary will be president (she isn't) remain will be the outcome (it wasn't) labour will be elected (they weren't) thanks for a glimmer of positivity op

Thank you for the positivity, OP. Good luck & fingers crossed for you & your colleagues in kicking this virus’s arse.

I work in aviation, an industry which has been decimated by covid. The work you & your colleagues are doing is incredibly important, for public health and for the economies on which our health services depend.

I don't think it would be rushed out would it? Why would pharmaceutical companies want to expose themselves to mass lawsuits down the line? And forfeit their reputations?

I don't think it would be rushed out would it? Why would pharmaceutical companies want to expose themselves to mass lawsuits down the line? And forfeit their reputations?

And governments have an equally vested interest in a vaccine being safe - there's no way they'll roll out anything that risks just swapping one health crisis for another one.

The BBC global podcast was discussing the importance of making sure the vaccine was available to all and not just the highest bidder. To this end the money is being provided upfront and not at the end when any drug is usually sold. Im still suspicious that the US will end up trying to get access to it first as a trump is an unscrupulous bastard but hopefully it will work AND be available to all.

An Oxford bod working on a vaccine said it had already done well at the animal stage of testing so it does sound as if at least one team have gone through that stage

www.google.com/amp/s/www.nytimes.com/2020/04/27/world/europe/coronavirus-vaccine-update-oxford.amp.html

This article talks about the vaccine being effective in monkeys so don't read if it you get upset about animal testing. But that aside it's brilliant news.

The biggest problem with the testing is that with lockdown still going on they’re going to struggle to get enough cases of the virus in the control groups to prove efficacy. Not a lot you can do about that, just recruit an awful lot of testers and be patient.

There was a piece and interview with the oxford academic in the Sunday Times a couple of weeks ago which discussed this - I have forgotten the details but I think they were hoping to do trials in a country which wasn't locking down. I posted sharetoken links, not sure if they'll still work and now I can't find the thread... sorry, not very helpful!