Anyone taking part in the Response Medical Trial or any other medical trial?

[sizethree]

Hi, I'm taking part in the Response medical trial and wondering if anyone else on here is too?
It's been a very difficult year and a half and I have had three consecutive miscarriages, 1st in Nov 2013 at 12 weeks, 2nd in July 2014 at 7 weeks, 3rd in Nov 2014 at 9 weeks. It's a 4 month waiting list for my Recurrent Miscarriage Clinic so I'm taking part in the trial as want to keep things moving as worried I'm running out of time (I'm 36 this year - although I was 33 when first started TTC) but I'm in the 2WW and feeling terrified.
There's a lot of extra support offered as part of the trial but I'm feeling a bit lonely and out on a limb about it.
Anyone else on the same boat or had medical trial experience?

Yippee that's great news sizethree!! Just keep your cool and get through today. Nearly there my lovely, bet it's been a loooong day!
Just try not to think about it too much, that's what's been helping me! How many dpo are you?

Popped into town with dh earlier and bumped into my mum and dad and went for a cuppa.
We were saying how it's so hard that we can't get excited etc, and unfair. With ds I was planning everything as mc didn't even occur to me!!
She said 'you WILL have this one!' (She's a retired mw). We'll just have to see won't we.
I just want to tell everyone, especially ds as he's 3.6 now so he would be so excited, but we just can't :( so unfair!

Claire you catch pretty quickly don't you? Hopefully because you've got onto the trial you won't have to go through the heartache any more x

I guess once you 've had a miscarriage finding out your pregnant again will never really be the celebration it should be . That's really sad Part. Miscarriage never really entered my head with ds but I can't imagine never not thinking about it now. What a wonderful career your mum had I wish I had became a midwife I still may look into that in a few years as its my dream.
You can tell ds soon enough he 'll be so excited I bet.
I'm having a bad couple of days as sorted through my ds baby clothes to look for things for my sister and she's been none stop pregnancy/New baby talk (understandably) these last few days xx

Choccywoccydodah I have caught quickly this last year yes but for some reason I feel panicky about it all this time xx

It's totally not sunk in yet. Hopefully my positive will show up string enough tomorrow to start the injections. But I still kind of feel like I'm imaging things!
Also, the trial manager said that I'm the first in Scotland to be starting the trial. Which is quite exciting. As although I know it's completed randomised, I can't help thinking I must have better odds with being the first (which is statistical nonsense I know!)
Not going to retest tonight but I will try not to be very hydrated as I want my wee to be really good for strong BFP.
Yep, pregnancy after miscarriage is a real mixed bag of emotions. It's impossible to regain that blissful innocence, but equally you can't help get carried away with planning the future. Due date, what size a bump would be at that event in a few months etc.
I'm extra nervous as I don't have any children at all yet, so I don't know I am actually able to carry to full term. Very much hoping that this will be my chance.
Sometimes I can't believe the babies I've lost. I don't know how you've coped so well Choccy. You have incredible tenancity.

Hoe exciting sizethree! Yes it would be amazing if you got the drug esp being the first :) you'll go down in history lol!
I'm sure you'll be fine in the morning. As long as it's min 4 hours it should be ok. Keep positive thoughts!

So, sickness has hit me tonight like a truck. Dh went out to get some chips and the thought made me (literally) sick in my mouth. I've just had 3 pieces of toast to try and fill me and settle me.

*2 not 3!

Yay for sickness. It's a good sign that your horemones are raging in all the right ways! I remember craving haribo, the fruity sweet softness took the edge off, especially on the bus in the morning. But cravings are so random.
My tests showed up faster and darker today. So hopefully they'll wirk at the hospital at 11am. But I'll need to hide them from now on as I iften freaked mysf out with previous pregnancies by noticing the lines get lighter before I miscarry. Need to steer clear of that spiral on this one.
Gosh, it's all becoming a bit more real.

Fab news with the tests! Now pack them away! I'm like you testing and testing, but I haven't tested since I got a + at the hospital.
Hope all goes well today, exciting stuff!!!
Funnily enough from about 10 weeks with ds I craved jelly and jelly sweets ha ha :)

Just had my appt, all good. Scan booked for 1pm next tues eeeeeeeek!!! Gonna be a loooooooong week!

Thinking of you sizethree x

brilliant news sizethree hope your app goes well.x

Glad all went ok choccywoccydodah yes no doubt this week will drag but it will soon be here for you xx

How was today sizethree? :)

It was long and exhausting.
As I'm the first participant there was a lot of waiting around, but all sorted evebtually. Missed a lot of work today, but my health comes first.
As I'm 2 days before my period is due, I took 1 injection today and take one tomorrow, but need to go back in on Thursday for next weeks pack. My appointments will be on Thursdays. It's so much to take in!
The hardest bit was injecting myself. I've never had to do it before (I'd make a terrible drug addict!) and felt very apprehensive. But when I did it I don't know why I fussed so much as I couldn't even feel it.
So I'm trying to stay cool, calm and collected. And try to remember that I've got the same chance as any other woman to have the actual drug and I'll be getting the best possible care.
Still doesn't feel real yet.
How're you getting on?

So glad all is ok sizethree :) was starting to panic when we'd not heard! Don't do that to us lol!
Injections are a doddle aren't they :)
I had to go back at 4 weeks too hence my first appt was the Friday and had to go back tues.
So exciting isn't it!!
Does your work know about your appts?

You'll be here soon Claire, we're both rooting for you!!!!

All good here. The dreaded day is tomorrow, but am feeling really positive. Just want to get to friday, then my scan tues.
We're seeing some friends saturday who know all about what's been going on, (it was her who was here with her ds and we had to shovel out the door when I had my very first appt and they sent me home due to a non + at Hosp, can't remember if I mentioned that), but we've not told them I'm preg. Terrified questions will be asked tbh. I don't mind them knowing, but just wanted to get to the scan first.

*dd not ds!

just take every day at a time.....you will both get there and all will work out I really hope so for you both. choccywoccydodah once you get weekend over you 'll feel so much better and then your scan will be here. how exciting.
Glad all ok yesterday sizethree.
you 'll both be experts by the time I start injections!x

Sorry for late reply yesterday. I had to rush back into work then I had a life drawing class.
I've had to tell 2 people at work. I work in a big design agency and timings are pretty tight for work flow. I started in Jube, and suffered two out of my three miscarriages within this job so have had to take a lot of time off. They have been wonderfully supportive and I feel a lot calmer this time around knowing that they are looking out for me and know the plans.
I've told a couple of close friends too, as previously I'd only told them once I'd miscarried. But this time around I need as much support and handholding a possible, so I've got a good network around me if the worst happenes.
It's not long at all til your scan Choccy. How exciting!
Claire you'll be a pro on this trial with all our combined knowledge

Morning ladies how are we?

All good here, am officially the same as my longest now :)

It's great you have the support sizethree. It's really what we need.
Funny actually a friend text me an hour ago telling me she had a dream about me last night and did I have anything to tell her!! She ALWAYS has a dream about me a few days after I catch, it's really odd!!
Anyway I've told her. It's actually nice to have told someone tbh.

I'm having a little pale yellow discharge too since yesterday and started to panic but apparently it's normal in early pregnancy! Jeez, this is going to be a long 8 months!!

That's great news Choccy. These milestones are so important. I'm very relieved for you.
Yes, I decided to tell a few people as they are the ones that know about the pre you'd MCs, and it must've been strange them learning if the MCs but never actually knowing when i was pregnant. I'd only ever discussed it after. But I'm nog believing in 'temptung fate' this time.
I'm feeling terrified still and so paranoid every time I wipe and at any niggle of pain.
Have you had cramps and stretchies Choccy?
Today is the day my period would have been due so I'm extra alert to any physical symptom.
But my boobs are sore and I'm shattered and feeling awful. All good signs I reckon.
And yesterday after I took my injection, about an hour later I felt a big whoosh of pain in my boobs and abdomin which I am convincing myself is the drugs working and making sure horemones and implantation is super secured!
How are you Claie? What CD are you on?

Ha, I do should've proof read that! So many typos, sorry.

Hi ladies
Ahh that's excellent choccywoccydodah, I'm so pleased your as far as you 've been before.

sizethree glad your okay and sounds like your symptons are starting so that's a good start. its good that you feel like the injections are helping...... I'm on CD7 so with my cycles varying from 24-32 days I have to start doing opks tomorrow I think. I might use my cheapies for 1st few days as the ones they gave me won't last long.......I'm still on 1st period since miscarriage but think it's almost finished.
hope you two are feeling positive once you get weekend out of way you both have apps next week. yippee.
scan for you choccywoccydodah eeek bet you can't wait xx

Ooooo Claire yes get testing!!! You never know you may have a quick cycle this time! Sending you lots of baby dust as they say :) would be amazing for you to catch this month.

Sizethree all your symptoms sound great! Yes I had the stretching thing and slightly crampy. Glad you're finding the jabs ok.

All good here, today is my official furthest day!!!!
I am feeling ok, I haven't had many symptoms as such, but I had absolutely nothing with ds either, so am hoping I kinda go the same way, although a little sickness would be reassuring!
All I've had for the last couple of days is tiredness, slight nipple tenderness and extremely smelly farts!!!! To a point I don't want to even fart on my own as it makes me feel sick!!! Like cabbage or rotten eggs. Dh was not impressed with me yesterday in the car, and even ds told me last night I was smelly!

Yay! Congrats Choccy. Great milestone.
Smelly farts Huh. Full of the joys of pregnancy! I'm always quite pumpy so haven't noticed an increase. Classy one aren't i!
My boobies are achey and still pully stretchy cramps, hopefully indicating that everything is nestling in.
Still AGES til my scan. And I get very nervous of them as never have good news at that time. I get scanxiety!
But again, I'm just taking one day at a time.
How are you Claire? You started ov testing?

Hi ladies I'm okay thanks ...... congrats choccy on your furthest day brilliant.
Your scan will soon come round sizethree easy for me to say I know but I also would be terrified of a scan.... to be honest I'm terrified of a positive pregnancy test..... I opk tested earlier negative but that's what I expected its usually day 14-16 but it could be anytime this month.

so pleased you ladies are both well xx

Any news Claire? Ov + yet?

How you doing sizethree?

All good here. Still no spotting or anything WOOHOO!!

Felling ok. Bit sicky today with no appetite, but had something Philly cheese and crackers but didn't really help.
Sore nips and tiredness is really all I'm feeling mostly. And today I just feel freezing!

Told our friends last night. They're happy for us if a bit gutted as we're all going to Dublin in April and I won't be drinking lol. Not that I do really anyway, but you know what I mean.
It's nice to tell someone though :)
They're the only ones who know about the scan tues, parents think it's weds